المؤلفون: Andrew W. Robertson (1411456), Jorge Sandoval (5316437), Osama G. Mohamed (10519783), Yihao Zhuang (10519786), Erin E. Gallagher (5316443), Jennifer Schmidt (161812), Lisa Caratelli (10519789), Arya Menon (4592212), Pamela J. Schultz (493234), Rachel M. Torrez (10519792), Catherine L. Hay (10519795), Bailey A. Bell (10519798), Paul A. Price (10519801), Amanda L. Garner (163009), Ashootosh Tripathi (1485115)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Genetics, Molecular Biology, Pharmacology, Immunology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, molecule ligands, molecule modulators, pre-miR -21-selective maturation in., product inhibitor discovery, MicroRNA Processing, protein translation, high-throughput screening, RNA-binding inhibitors, HTS campaign, chemical space, gene expression, depsipeptide class, Dicer-mediated miRNA processing, noncoding RNAs, enzyme-linked click chemistry assay, Cat-ELCCA MicroRNAs

العلاقة: https://figshare.com/articles/journal_contribution/Discovery_of_Surfactins_as_Inhibitors_of_MicroRNA_Processing_Using_Cat-ELCCA/14363974Test

الإتاحة: https://doi.org/10.1021/acsmedchemlett.1c00046.s002Test

المؤلفون: Emmanuelle Thinon, Ursula R. Rodgers, Antonio D. Konitsiotis, Anthony I. Magee, Naoko Masumoto, Edward W. Tate, George Bodakh, Raymond J. Owens, Thomas Lanyon-Hogg

المساهمون: Cancer Research UK

المصدر: Analytical Biochemistry

مصطلحات موضوعية: YnC15, heptadec-16-ynoic acid, Peptide, Protein lipidation, 01 natural sciences, Biochemistry, OTG, n-octyl β-d-glucopyranoside, Substrate Specificity, PATHWAY, PCR, polymerase chain reaction, SONIC-HEDGEHOG, Protein palmitoylation, TBTA, tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine, Enzyme Inhibitors, Sonic hedgehog, PROTEIN LIPIDATION, chemistry.chemical_classification, 0303 health sciences, Palmitoyl Coenzyme A, biology, Click chemistry, Chemistry, HRP, horseradish peroxidase, HTS, high-throughput screen, Hedgehog signaling pathway, MBOAT, membrane bound O-acyltransferase, Acyltransferase, Hh, hedgehog, Physical Sciences, Fatty Acids, Unsaturated, Shh, sonic hedgehog, RT, room temperature, Oligopeptides, Life Sciences & Biomedicine, 0301 Analytical Chemistry, CoA, coenzyme A, Biochemistry & Molecular Biology, SDS, sodium dodecyl sulfate, TCEP, tris(2-carboxyethyl)phosphine, Lipoylation, Recombinant Fusion Proteins, Detergents, cat–ELCCA, catalytic assay using an enzyme-linked click chemistry assay, PBS, phosphate-buffered saline, Biophysics, Enzyme-Linked Immunosorbent Assay, click–ELISA, click chemistry armed enzyme-linked immunosorbent assay, CHAPS, 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate, HEK293a, human embryonic kidney 293a, Article, Biochemical Research Methods, PROBES, 03 medical and health sciences, Palmitoylation, HHAT, Hhat, hedgehog acyltransferase, 0399 Other Chemical Sciences, Hedgehog acyltransferase, Humans, Biotinylation, Hedgehog Proteins, Maltose, DDM, n-dodecyl β-d-maltopyranoside, Molecular Biology, PAGE, polyacrylamide gel electrophoresis, 030304 developmental biology, Science & Technology, 010405 organic chemistry, HUMAN-CELLS, GOAT, ghrelin-O-acyltransferase, Chemistry, Analytical, CANCER PROGRESSION, 0601 Biochemistry And Cell Biology, Cell Biology, Peptide Fragments, MBOAT, 0104 chemical sciences, HEK293 Cells, Immobilized Proteins, Solubility, biology.protein, BSA, bovine serum albumin, Streptavidin, PTM, posttranslational modification, INHIBITORS, Protein Processing, Post-Translational, Acyltransferases

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deba21c0917231d911f1a22f0e2c2864Test
https://doi.org/10.1016/j.ab.2015.08.025Test