التفاصيل البيبلوغرافية
| العنوان: |
State of local cervical immunity in women with infertility ; Состояние локального цервикального иммунитета у женщин с бесплодием ; Стан локального цервікального імунітету в жінок із непліддям |
| المؤلفون: |
Середа, К.В. |
| المصدر: |
Ukrainian Journal «Health of Woman»; No. 5(168) (2023): Ukrainian Journal Health of Woman; 28-33 ; Ukrainian Journal «Health of Woman»; № 5(168) (2023): Ukrainian Journal Health of Woman; 28-33 ; Український журнал "Здоров'я жінки"; № 5(168) (2023): Український журнал Здоров’я жінки; 28-33 ; 2786-6017 ; 2786-6009 |
| بيانات النشر: |
Group of Companies Med Expert, LLC |
| سنة النشر: |
2023 |
| المجموعة: |
Scientific Periodicals of Ukraine (Ukrainian Research and Academic Network) / Наукова періодика України |
| مصطلحات موضوعية: |
бесплодие, интерлейкины, ранние цервикальные поражения, лактоферрин, секреторный ингибитор лейкоцитарной протеиназы, непліддя, інтерлейкіни, ранні цервікальні ураження, лактоферин, секреторний інгібітор лейкоцитарної протеїнази, infertility, interleukins, early cervical lesions, lactoferrin, secretory leukocyte proteinase inhibitor |
| الوصف: |
Purpose - to study certain indicators of local immunity in women with infertility of various origins and early cervical lesions Materials and methods. The state of local cervical immunity was examined in 496 women, who were divided into groups depending on the cause of infertility, and each group was divided into subgroups A and B depending on the presence of cervical epithelial lesions. 128 women in the Group I had an endocrine cause, 122 patients in the Group II had a tubal-peritoneal factor of infertility, and 121 patients in the Group III had a male factor of fertility disorder. 125 healthy women formed the control group (CG). Subgroup A included women with NILM liquid cytology results: IA - 100 women, IIA - 70, IIIA - 68, GCA - 88. Subgroups B included women with ASC-US (atypical squamous cells of undetermined significance), LSIL (low-grade squamous intraepithelial lesion) and HSIL (high-grade squamous intraepithelial lesion): IB - 28 patients, IIB - 52, IIIB - 53, CGB - 37. In all patients, the content of interleukin-8 and -6 (IL-8, IL-6), lactoferrin and secretory leukocyte proteinase inhibitor in the material obtained for liquid cytology was determined by polymerase chain reaction. Results. In all patients with infertility, an increased concentration of secretory leukocyte proteinase inhibitor (from 314.1 to 398.7 pg/ml) and a decreased lactoferrin content (from 13.6 to 28.6 pg/ml) were found compared to the group of healthy women (114.8 and 64.8 pg/ml, respectively). In women with tubal and peritoneal infertility and male infertility, higher concentrations of IL-8 were found (659.9 to 878.8 pg/ml) than in the group of endocrine infertility (302.9 pg/ml) and in the group of healthy women (282.4 pg/ml). Conclusions. IL-8 content in cervical mucus is probably higher in women with tubal-peritoneal infertility (838 pg/ml) and male infertility (659.9 pg/ml) than in healthy women (289.4 pg/ml) and in women with endocrine infertility (302.3 pg/ml). The content of secretory inhibitor of leukocyte proteinase in ... |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
Ukrainian |
| العلاقة: |
http://ujhw.med-expert.com.ua/article/view/296779/289764Test; http://ujhw.med-expert.com.ua/article/view/296779Test |
| الإتاحة: |
http://ujhw.med-expert.com.ua/article/view/296779Test |
| حقوق: |
Авторське право (c) 2023 Український журнал Здоров’я жінки ; https://creativecommons.org/licenses/by-nc/4.0Test/ |
| رقم الانضمام: |
edsbas.2B3E50B2 |
| قاعدة البيانات: |
BASE |
