المؤلفون: Kaatje Lenaerts, Joep Grootjans, Anna M. Kip, Marco Manca, Steven W.M. Olde Damink, Bas Boonen, Cornelis H. C. Dejong, Wim A. Buurman, M'hamed Hadfoune, Joep P. M. Derikx, Erik A.L. Biessen

المساهمون: Gastroenterology and Hepatology, Tytgat Institute for Liver and Intestinal Research, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Paediatric Surgery, ARD - Amsterdam Reproduction and Development, RS: NUTRIM - R2 - Liver and digestive health, Surgery, Pathologie, RS: Carim - B07 The vulnerable plaque: makers and markers, MUMC+: MA Heelkunde (9)

المصدر: CMGH, 13(3), 681-694. Elsevier Inc.
Cellular and Molecular Gastroenterology and Hepatology : CMGH 13(3), 681-694 (2022). doi:10.1016/j.jcmgh.2021.11.001
Cellular and molecular gastroenterology and hepatology, 13(3), 681-694. Elsevier Inc.
Cellular and Molecular Gastroenterology and Hepatology

مصطلحات موضوعية: ATF4, activating transcription factor 4, CELL-SURVIVAL, eIF2α, eukaryotic translation initiation factor 2A, INDUCED INFLAMMATION, mEGF, mouse epidermal growth factor, EM, Electron microscopy, ROCK, Rho kinase, Intestinal Ischemia-Reperfusion, GADD34, growth arrest and DNA-damage-inducible protein, Transcriptome, ACTIVATION, UPR, unfolded protein response, ENDOPLASMIC-RETICULUM STRESS, Gene expression, I, ischemia, Original Research, Human Intestinal Organoids, Gastroenterology, DEATH, CHOP, CCAAT/enhancer-binding protein homologous protein, BiP, binding immunoglobulin protein, Endoplasmic Reticulum Stress, Cell biology, medicine.anatomical_structure, XBP1, X-box binding protein 1, Reperfusion Injury, JNK, c-Jun N-terminal kinase, qPCR, quantitative polymerase chain reaction, R, reperfusion, HYPOXIA-INDUCIBLE FACTOR, FACTOR-I, NF-κB, nuclear factor-κB, IRE1, inositol-requiring enzyme 1, KAPPA-B, Biology, KEGG, Kyoto Encyclopedia of Genes and Genomes, ER, endoplasmic reticulum, Organoid, medicine, KINASE, Integrated stress response, Humans, C, control, Transcriptomics, GO, gene ontology, Hepatology, Microarray analysis techniques, XBP1s, spliced X-box binding protein 1, Endoplasmic reticulum, PERK, protein kinase R-like ER kinase, Activating Transcription Factor 4, Small intestine, ISRIB, integrated stress response inhibitor, ER, Unfolded protein response, Unfolded Protein Response, HIF1A, hypoxia-inducible factor 1-α, Transcription Factor CHOP, MAPK, mitogen-activated protein kinase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76ba4ffc78867321b72f85db21a76d04Test
http://www.scopus.com/inward/record.url?scp=85121206348&partnerID=8YFLogxKTest

المؤلفون: Jennifer E. Gallagher, Dorothy Kisielewski, John F. Dillon, Shaun V. Walsh, Diane Cassidy, David J. Harrison, Ritu Sharma, Tadashi Honda, John D. Hayes, Alison D. McNeilly, Michael L.J. Ashford, Albena T. Dinkova-Kostova, Rory J. McCrimmon

المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 5, Iss 3, Pp 367-398 (2018)

مصطلحات موضوعية: NQO1, NAD(P)H:quinone oxidoreductase 1, TNF-α, tumor necrosis factor-α, IRE1α, inositol requiring kinase-1α, SCAD, short-chain acyl-CoA dehydrogenase, C/EBP, CCAAT/enhancer-binding protein, PCR, polymerase chain reaction, UPR, unfolded protein response, 0302 clinical medicine, Fibrosis, MGPAT, mitochondrial glycerol-3-phosphate acetyltransferase, ATF4, activating transcription factor-4, DGAT2, diacylglycerol acyltransferase-2, LXRα, liver X receptor α, Glucose homeostasis, eIf2α, eukaryotic translation initiation factor 2A, IKK, IκB kinase, ACOT7, acetyl-CoA thioesterase 7, Original Research, TGFβ, transforming growth factor beta-1, SLC7A11, solute carrier family 7 member 11, GSSG, oxidized glutathione, MTTP, microsomal triglyceride transfer protein, NASH, Gastroenterology, TXN1, thioredoxin-1, 3. Good health, ChREBP, carbohydrate-responsive element-binding protein, 030220 oncology & carcinogenesis, NASH, nonalcoholic steatohepatitis, medicine.medical_specialty, PARP, poly ADP ribose polymerase, qRT-PCR, quantitative reverse transcriptase PCR, GSTM1, glutathione S-transferase Mu-1, GCLC, glutamate-cysteine ligase catalytic, Nrf2, ACACA, acetyl-CoA carboxylase alpha, 03 medical and health sciences, FXR, farnesoid X receptor, Nrf2, NF-E2 p45-related factor 2, COX2, cyclooxygenase-2, Keap1, Kelch-like ECH-associated protein-1, PPARα, peroxisome proliferator-activated receptor α, PTT, pyruvate tolerance test, HMOX1, heme oxygenase-1, RC, regular chow, p58IPK, p58 inhibitor of the PKR kinase, medicine.disease, TBE-31, 030104 developmental biology, Endocrinology, COL1A1, collagen, type I, alpha-1, Unfolded protein response, CAT, catalase, 0301 basic medicine, PDI, protein disulfide isomerase, GSH, reduced glutathione, FASN, fatty acid synthase, BCL-2, B-cell lymphoma, MPO, myeloperoxidase, AP-1, activator protein 1, DMSO, dimethyl sulfoxide, medicine.disease_cause, SHP, small heterodimer partner, CDDO, 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid, CHOP, C/EBP homologous protein, TXNRD1, thioredoxin reductase-1, HF30Fr, high-fat diet with 30% fructose in drinking water, IκB, inhibitor of NF-κB, SFN, sulforaphane, ADRP, adipose differentiation-related protein, NAS, NAFLD activity score, GPX2, glutathione peroxidase-2, Chemistry, MCP-1, monocyte chemotactic protein-1, XBP1, X-box binding protein-1, SREBP-1c, sterol regulatory element-binding protein-1c, Lipogenesis, GTT, glucose tolerance test, PERK, PRK-like endoplasmic reticulum kinase, PTGR1, prostaglandin reductase-1, GSTA4, glutathione S-transferase Alpha-4, medicine.symptom, NAFLD, non-alcoholic fatty liver disease, α-SMA, alpha smooth muscle actin, ACOX2, acetyl-CoA oxidase 2, HFFr, high-fat diet with fructose in drinking water, NF-κB, nuclear factor-κB, GCLM, glutamate-cysteine ligase modifier, Inflammation, JNK1, c-Jun N-terminal kinase 1, CD36, cluster of differentiation 36, ER, endoplasmic reticulum, Insulin resistance, HF, high-fat, HF55Fr, high-fat diet with 55% fructose in drinking water, Internal medicine, ATF6, activating transcription factor-6, medicine, ApoB, apolipoprotein B, lcsh:RC799-869, CES1G, carboxylesterase 1g, ITT, insulin tolerance test, MCD, methionine- and choline-deficient, ACLY, ATP citrate lyase, Hepatology, SCD1, stearoyl-CoA desaturase-1, NOS2, nitric oxide synthase-2, PRDX6, peroxiredoxin 6, PPARγ, peroxisome proliferator-activated receptor γ, BIP, binding immunoglobulin protein, H&E, hematoxylin and eosin, lcsh:Diseases of the digestive system. Gastroenterology, Steatosis, CPT1A, carnitine palmitoyltransferase 1a, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebdd8de56b5ba950a8c970d72cce7012Test
https://doi.org/10.1016/j.jcmgh.2017.11.016Test

المؤلفون: Thomas Lahlali, Marie-Laure Plissonnier, Cristina Romero-López, Maud Michelet, Benjamin Ducarouge, Alfredo Berzal-Herranz, Fabien Zoulim, Patrick Mehlen, Romain Parent

المساهمون: Centre de Recherche en Cancérologie de Lyon (UNICANCER/CRCL), Centre Léon Bérard [Lyon]-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Instituto de Parasitología y Biomedicina López-Neyra (IPBLN-CSIC), Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), This study was supported by the European Union (Marie Curie International Reintegration grant 248364), the Bullukian Foundation, the French National Agency for Acquired Immune Deficiency Syndrome and Viral Hepatitis Research (Agence nationale de recherches sur le sida et les hépatites virales, 2011-379), Ligue Contre le Cancer, and the DevWeCan French Laboratories of Excellence Network (Labex, ANR-10-LABX-61), European Project: 248364,EC:FP7:PEOPLE,FP7-PEOPLE-2009-RG,HCV-BOUND PROTEINS(2010), Duchange, Nathalie, Hepatitis C virus virion-bound proteins: identification in clinical samples and in vitro dissection of their importance in the viral life cycle - HCV-BOUND PROTEINS - - EC:FP7:PEOPLE2010-07-01 - 2014-06-30 - 248364 - VALID, Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)

المصدر: Cellular and Molecular Gastroenterology and Hepatology
Digital.CSIC. Repositorio Institucional del CSIC
instname
Cellular and Molecular Gastroenterology and Hepatology, 2016, 2 (3), pp.281-301.e9. ⟨10.1016/j.jcmgh.2015.12.011⟩
Cellular and Molecular Gastroenterology and Hepatology, Philadelphia, PA : American Gastroenterological Association, [2015]-, 2016, 2 (3), pp.281-301.e9. ⟨10.1016/j.jcmgh.2015.12.011⟩
Cellular and Molecular Gastroenterology and Hepatology, Vol 2, Iss 3, Pp 281-301.e9 (2016)

مصطلحات موضوعية: 0301 basic medicine, Translation, DR, dependence receptor, pBic, Bicistronic plasmid, Dependence receptor, UPR, NMIA, N-methyl-isatoic anhydride, UPR, unfolded protein response, eIF2α, Eukaryotic translation initiation factor 2A, RLuc, Renilla lucerifase, PP2A, protein phosphatase 2A, UNC5, uncoordinated phenotype-5, ATF6, activated transcription factor 6, Hepatocyte, Original Research, Tu, tunicamycin, Gastroenterology, Translation (biology), mRNA, messenger RNA, 3. Good health, Cell biology, UTR, untranslated region, DAPK, death-associated protein kinase, IRES, internal ribosome entry site, HCV, hepatitis C virus, IRE1α, inositol requiring enzyme 1α, PBS, phosphate-buffered saline, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Biology, FLuc, Firefly luciferase, PERK, protein kinase RNA (PKR)-like endoplasmic reticulum kinase, ER, endoplasmic reticulum, 03 medical and health sciences, lcsh:RC799-869, Protein kinase A, [SDV.BC] Life Sciences [q-bio]/Cellular Biology, DMS, dimethyl sulfate, Messenger RNA, VR1, vanilloid receptor 1, Hepatology, ATF6, Endoplasmic reticulum, fungi, LSL, (Lox-Stop-Lox), CMV, cytomegalovirus, Molecular biology, qRT-PCR, quantitative reverse-transcription polymerase chain reaction, Internal ribosome entry site, 030104 developmental biology, HBV, hepatitis B virus, PR65β, erine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform, DTT, dithiothreitol, siRNA, small interfering RNA, Netrin, Unfolded protein response, lcsh:Diseases of the digestive system. Gastroenterology, TUNEL, terminal deoxynucleotidyl transferase–mediated deoxyuridine triphosphate nick-end labeling, HCC, hepatocellular carcinoma

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4026a075c07c861fb902610f25a9d5cTest