المؤلفون: Jiao Li, Fei Wang, Zhen Li, Jingjing Feng, Yi Men, Jinming Han, Jiangwei Xia, Chen Zhang, Yilai Han, Teng Chen, Yinan Zhao, Sirui Zhou, Yuwei Da, Guoliang Chai, Junwei Hao

المصدر: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)

مصطلحات موضوعية: Myasthenia gravis, Actionable druggable genome, Mendelian randomization, Genetic colocalization, Cell-type specificity, Medicine

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1479-5876Test

الوصول الحر: https://doaj.org/article/277194df3b5345299b9bb784dac72bccTest

المؤلفون: Daniels, Alison

المساهمون: Haas, Juergen, Nair, Harish, Schwarze, Jurgen, Tait-Burkard, Christine

مصطلحات موضوعية: RNAi Screening, Respiratory Virus Infection, Acute respiratory infections, lower respiratory tract, RNAi human druggable genome screens, human Respiratory Syncytial Virus (RSV), Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Paramyxovirus, SARS-CoV-2, Vero E6 (African green monkey), Caki-1

الوصول الحر: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.884195Test

المؤلفون: Oprea, Tudor I., Bologa, Cristian, Holmes, Jayme, Mathias, Stephen, Metzger, Vincent T., Waller, Anna, Yang, Jeremy J., Leach, Andrew R., Jensen, Lars Juhl, Kelleher, Keith J., Sheils, Timothy K., Mathé, Ewy, Avram, Sorin, Edwards, Jeremy S.

المصدر: Oprea , T I , Bologa , C , Holmes , J , Mathias , S , Metzger , V T , Waller , A , Yang , J J , Leach , A R , Jensen , L J , Kelleher , K J , Sheils , T K , Mathé , E , Avram , S & Edwards , J S 2024 , ' Overview of the Knowledge Management Center for Illuminating the Druggable Genome ' , Drug Discovery Today , vol. 29 , no. 3 , 103882 . https://doi.org/10.1016/j.drudis.2024.103882Test

مصطلحات موضوعية: database, druggable genome, knowledge management, pharos

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1016/j.drudis.2024.103882Test
https://curis.ku.dk/portal/da/publications/overview-of-the-knowledge-management-center-for-illuminating-theTest-druggable-genome(eca22382-aacb-430c-ac1f-8dd1f665602e).html
https://curis.ku.dk/ws/files/382499950/1_s2.0_S1359644624000072_main.pdfTest

المؤلفون: Mariah V. Salcedo, Nathan Gravel, Abbas Keshavarzi, Liang-Chin Huang, Krzysztof J. Kochut, Natarajan Kannan

المصدر: PeerJ, Vol 11, p e15815 (2023)

مصطلحات موضوعية: Random walk, Illuminating Druggable Genome (IDG), Pathway prediction, Data integration, Ontologies, Link prediction, Medicine, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://peerj.com/articles/15815.pdfTest; https://peerj.com/articles/15815Test/; https://doaj.org/toc/2167-8359Test

الوصول الحر: https://doaj.org/article/f9a6f8aea0fa42169043d7129c3f323fTest

المؤلفون: Manju Anandakrishnan, Karen E. Ross, Chuming Chen, Vijay Shanker, Julie Cowart, Cathy H. Wu

المصدر: PeerJ, Vol 11, p e16164 (2023)

مصطلحات موضوعية: Kinase-substrate prediction, Dark kinome, Illuminating the druggable genome, Protein phosphorylation, Text mining, Knowledge graph, Medicine, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://peerj.com/articles/16164.pdfTest; https://peerj.com/articles/16164Test/; https://doaj.org/toc/2167-8359Test

الوصول الحر: https://doaj.org/article/7f22cfd4ac3b4f05b4ac87e17b564fd2Test

المؤلفون: Maria P. Magariños, Anna Gaulton, Eloy Félix, Tevfik Kiziloren, Ricardo Arcila, Tudor I. Oprea, Andrew R. Leach

المصدر: PeerJ, Vol 11, p e15153 (2023)

مصطلحات موضوعية: Patents, Understudied targets, Bioactive compounds, Small molecules, Druggable genome, Drug targets, Medicine, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://peerj.com/articles/15153.pdfTest; https://peerj.com/articles/15153Test/; https://doaj.org/toc/2167-8359Test

الوصول الحر: https://doaj.org/article/5dbd917e301f45c7a2da3d708bdd1b1aTest

المؤلفون: Louis-Hippolyte Minvielle Moncla, Samuel Mathieu, Mame Sokhna Sylla, Yohan Bossé, Sébastien Thériault, Benoit J. Arsenault, Patrick Mathieu

المصدر: BMC Genomics, Vol 23, Iss 1, Pp 1-12 (2022)

مصطلحات موضوعية: Heart failure, Mendelian randomization, Blood protein, Network, Pathway, Druggable genome, Biotechnology, TP248.13-248.65, Genetics, QH426-470

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1471-2164Test

الوصول الحر: https://doaj.org/article/40ff65e02a6640889ea700a7aabc850eTest

المؤلفون: Alexander Lachmann, Kaeli A. Rizzo, Alon Bartal, Minji Jeon, Daniel J. B. Clarke, Avi Ma’ayan

المصدر: PeerJ, Vol 11, p e14927 (2023)

مصطلحات موضوعية: Transcriptomics, Gene expression, Gene function predictions, RNA-seq, Unsupervised learning, Druggable genome, Medicine, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://peerj.com/articles/14927.pdfTest; https://peerj.com/articles/14927Test/; https://doaj.org/toc/2167-8359Test

الوصول الحر: https://doaj.org/article/e654143c0e6244b78659b1b1d9883474Test

المؤلفون: Arnaud Chignon, Samuel Mathieu, Anne Rufiange, Déborah Argaud, Pierre Voisine, Yohan Bossé, Benoit J. Arsenault, Sébastien Thériault, Patrick Mathieu

المصدر: Human Genomics, Vol 16, Iss 1, Pp 1-17 (2022)

مصطلحات موضوعية: Atherosclerosis, Coronary artery disease, Genes, 3D genome, Mendelian randomization, Druggable genome, Medicine, Genetics, QH426-470

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1479-7364Test

الوصول الحر: https://doaj.org/article/59cd3c5154c147f89fff974ce254a412Test

المؤلفون: Khoa Nguyen, Julia Boehling, Minh N. Tran, Thomas Cheng, Andrew Rivera, Bridgette M. Collins-Burow, Sean B. Lee, David H. Drewry, Matthew E. Burow

المصدر: Cancers ; Volume 15 ; Issue 7 ; Pages: 2067

مصطلحات موضوعية: NEK family, kinase, cancer signaling, KMPlot, cosmic mutation, bioinformatics, illuminating the druggable genome, understudied kinase, dark kinome

وصف الملف: application/pdf

العلاقة: Tumor Microenvironment; https://dx.doi.org/10.3390/cancers15072067Test

الإتاحة: https://doi.org/10.3390/cancers15072067Test