المؤلفون: Anja U. Bräuer, Maria Vittoria Cubellis, Georg Fuellen, Jan Lukas, Anne-Katrin Giese, Arndt Rolfs, Mathias Ernst, Giuseppina Andreotti, Stephan Struckmann, Andreas Hermann, Linda Rebecca Haake, Anne-Marie Knospe, Claudia Cozma, Valentina Citro, Susanne Seemann, Chiara Cimmaruta, Dirk Koczan

المساهمون: Seemann, S., Ernst, M., Cimmaruta, C., Struckmann, S., Cozma, C., Koczan, D., Knospe, A. -M., Haake, L. R., Citro, V., Brauer, A. U., Andreotti, G., Cubellis, M. V., Fuellen, G., Hermann, A., Giese, A. -K., Rolfs, A., Lukas, J.

المصدر: Biochemical journal (Online) (2020). doi:10.1042/BCJ20190513
info:cnr-pdr/source/autori:Susanne Seemann ; Mathias Ernst ; Chiara Cimmaruta ; Stephan Struckmann ; Claudia Cozma ; Dirk Koczan ; Anne-Marie Knospe ; Linda R Haake ; Valentina Citro ; Anja U Bräuer ; Giuseppina Andreotti ; Maria V Cubellis ; Georg Fuellen ; Andreas Hermann ; Anne-Katrin Giese ; Arndt Rolfs ; Jan Lukas/titolo:Proteostasis regulators modulate proteasomal activity and gene expression to attenuate multiple phenotypesin Fabry disease/doi:10.1042%2FBCJ20190513/rivista:Biochemical journal (Online)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume
The biochemical journal / Reviews 477(2), 359-380 (2020). doi:10.1042/BCJ20190513
Biochemical Journal

مصطلحات موضوعية: lysosomal enzyme, genetics [Proteasome Endopeptidase Complex], Endoplasmic Reticulum, Biochemistry, genetics [Lysosomes], Molecular Bases of Health & Disease, metabolism [Lysosomes], transcriptomics, Lysosomal Storage Disease, genetics [alpha-Galactosidase], 0302 clinical medicine, metabolism [Endoplasmic Reticulum], Sphingosine, Gene expression, protein misfolding, Proteostasi, Research Articles, 0303 health sciences, therapeutic use [1-Deoxynojirimycin], biology, Pharmacology & Toxicology, genetics [Lysosomal Storage Diseases], Lysosome, Cell biology, genetics [Proteostasis], Protein Transport, drug effects [Protein Transport], 030220 oncology & carcinogenesis, ddc:540, Fibroblast, Translational Science, metabolism [Sphingosine], metabolism [Fibroblasts], Human, metabolism [Biomarkers], medicine.drug, drug therapy [Fabry Disease], Proteasome Endopeptidase Complex, 1-Deoxynojirimycin, enzymology [Fabry Disease], drug therapy [Lysosomal Storage Diseases], genetics [Mutation, Missense], Mutation, Missense, analogs & derivatives [Sphingosine], migalastat, enzymology [Lysosomes], Context (language use), Gene Expression Regulation, Enzymologic, 03 medical and health sciences, medicine, Humans, globotriaosylsphingosine, metabolism [Proteasome Endopeptidase Complex], pathology [Lysosomal Storage Diseases], Molecular Biology, drug effects [Gene Expression Regulation, Enzymologic], 030304 developmental biology, drug effects [Fibroblasts], genetics [Fabry Disease], Alpha-galactosidase, enzymology [Lysosomal Storage Diseases], proteasome inhibitor, Endoplasmic reticulum, transcriptomic, Biomarker, analogs & derivatives [1-Deoxynojirimycin], Cell Biology, Fibroblasts, medicine.disease, Therapeutics & Molecular Medicine, Fabry disease, Lysosomal Storage Diseases, Metabolism, Proteostasis, Proteasome, alpha-Galactosidase, Proteasome inhibitor, biology.protein, Fabry Disease, Lysosomes, genetics [Endoplasmic Reticulum], pathology [Fabry Disease], Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfda54713078b2d84fa25ecc480bef0aTest
https://doi.org/10.1042/bcj20190513Test

المؤلفون: Inga Antyborzec, Valerie B. O'Leary, J. Oliver Dolly, Saak V. Ovsepian, Laszlo Zaborszky, Jochen Herms

المصدر: Brain structure & function 219(5), 1527-1541 (2013). doi:10.1007/s00429-013-0583-x

مصطلحات موضوعية: metabolism [Choline O-Acetyltransferase], pharmacology [Sodium Channel Blockers], Vesicular Transport Proteins, pharmacology [Enzyme Inhibitors], Receptor, Nerve Growth Factor, metabolism [Cholinergic Neurons], rab7 protein, chemistry.chemical_compound, pharmacology [Tetrodotoxin], metabolism [Vesicular Transport Proteins], metabolism [Peptide Fragments], metabolism [Receptor, Nerve Growth Factor], Enzyme Inhibitors, drug effects [Lysosomes], Cells, Cultured, Late endosome, Basal forebrain, biology, General Neuroscience, pharmacology [Neurotoxins], Age Factors, amyloid beta-protein (1-42), metabolism [rab GTP-Binding Proteins], Cholinergic Neurons, Cell biology, Protein Transport, drug effects [Protein Transport], pharmacology [Peptide Fragments], Thapsigargin, Anatomy, physiology [Lysosomes], Sodium Channel Blockers, Neurotrophin, medicine.medical_specialty, Histology, SERCA, Amyloid beta, Neurotoxins, metabolism [Amyloid beta-Peptides], Tetrodotoxin, Article, Choline O-Acetyltransferase, early endosome antigen 1, Prosencephalon, Lysosomal-Associated Membrane Protein 1, Internal medicine, pharmacology [Thapsigargin], medicine, Animals, Channel blocker, ddc:610, Cholinergic neuron, drug effects [Cholinergic Neurons], Amyloid beta-Peptides, metabolism [Lysosomal-Associated Membrane Protein 1], rab7 GTP-Binding Proteins, Peptide Fragments, Rats, cytology [Prosencephalon], Endocrinology, Animals, Newborn, chemistry, rab GTP-Binding Proteins, pharmacology [Amyloid beta-Peptides], biology.protein, Lysosomes

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27c0b743b2ba9c6e9d9b218209022c3cTest
https://doi.org/10.1007/s00429-013-0583-xTest

المؤلفون: Beat Lutz, Tanja Brigadski, Raik Rönicke, Bianca Seifert, Julia Leschik, Volkmar Lessmann, Klaus G. Reymann, Robert Eckenstaler

المصدر: Neural Plasticity
Neural Plasticity, Vol 2016 (2016)
Neural plasticity 2016, 1-15 (2016). doi:10.1155/2016/4145708

مصطلحات موضوعية: 0301 basic medicine, drug effects [Hippocampus], Hippocampus, metabolism [Hippocampus], Hippocampal formation, 0302 clinical medicine, Cells, Cultured, Neurons, biology, Chemistry, toxicity [Peptide Fragments], amyloid beta-protein (1-42), Transport protein, Vesicular transport protein, Protein Transport, Neurology, metabolism [Brain-Derived Neurotrophic Factor], metabolism [Neurons], drug effects [Protein Transport], metabolism [Transport Vesicles], Neurotrophin, Research Article, Article Subject, Amyloid beta, drug effects [Transport Vesicles], Mice, Transgenic, lcsh:RC321-571, 03 medical and health sciences, drug effects [Neurons], Animals, Humans, ddc:610, Transport Vesicles, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Brain-derived neurotrophic factor, Amyloid beta-Peptides, Brain-Derived Neurotrophic Factor, Peptide Fragments, toxicity [Amyloid beta-Peptides], Mice, Inbred C57BL, 030104 developmental biology, nervous system, Animals, Newborn, biology.protein, Axoplasmic transport, physiology [Protein Transport], Neurology (clinical), Neuroscience, 030217 neurology & neurosurgery

وصف الملف: text/xhtml

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08466d6312713baebc71daa7f6d2aa42Test
https://pubmed.ncbi.nlm.nih.gov/26881108Test

المؤلفون: Urszula Hibner, Maciej Lipko, Magdalena Kijewska, Bozena Kaminska, Aneta Kwiatkowska

المساهمون: Institut de Génétique Moléculaire de Montpellier (IGMM), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)

المصدر: Biochimica et Biophysica Acta-Molecular Cell Research
Biochimica et Biophysica Acta-Molecular Cell Research, Elsevier, 2011, 1813 (5), pp.655--67. ⟨10.1016/j.bbamcr.2011.01.020⟩

مصطلحات موضوعية: Transcription, Genetic, Mice, Phosphatidylinositol 3-Kinases, 0302 clinical medicine, Invasion, Cell Movement, Pseudopodia, Phosphorylation, Migration, Phosphoinositide-3 Kinase Inhibitors, 0303 health sciences, NF-kappa B, Cell biology, Protein Transport, 030220 oncology & carcinogenesis, Cyclosporine, Matrix Metalloproteinase 2, MMPs, Signal transduction, Signal Transduction, Down-Regulation, Biology, Focal adhesion, 03 medical and health sciences, Transcriptional regulation, Downregulation and upregulation, Cell Line, Tumor, Matrix Metalloproteinase 14, Animals, Humans, Neoplasm Invasiveness, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Actins/metabolism Animals Cell Line, Cell adhesion, Protein kinase B, Cell Shape, Molecular Biology, PI3K/AKT/mTOR pathway, 030304 developmental biology, Genetic/drug effects, Akt/PKB signaling pathway, Cell Biology, Actins, PI3K/Akt signaling, Cyclosporin A, Focal Adhesion Kinase 1, Tumor Cell Movement/drug effects Cell Shape/drug effects Cyclosporine/pharmacology *Down-Regulation/drug effects Focal Adhesion Kinase 1/*metabolism Glioblastoma/*enzymology/pathology Humans Matrix Metalloproteinase 14/*metabolism Matrix Metalloproteinase 2/*metabolism Mice NF-kappa B/genetics Neoplasm Invasiveness Phosphatidylinositol 3-Kinases/antagonists & inhibitors/metabolism Phosphorylation/drug effects Protein Transport/drug effects Proto-Oncogene Proteins c-akt/antagonists & inhibitors/*metabolism Pseudopodia/drug effects/*enzymology Signal Transduction/drug effects Transcription, Glioblastoma, Proto-Oncogene Proteins c-akt

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4585402118e2ae396d48bae8f0e8a942Test

المؤلفون: Hans Zempel, Eva-Maria Mandelkow, Edda Thies, Eckhard Mandelkow

المصدر: The journal of neuroscience 30(36), 11938-11950 (2010). doi:10.1523/JNEUROSCI.2357-10.2010

مصطلحات موضوعية: Time Factors, Dendritic spine, methods [Microscopy, Electron, Transmission], Hippocampus, Microtubules, Rats, Sprague-Dawley, Adenosine Triphosphate, Neurofilament Proteins, metabolism [Calcium], Phosphorylation, metabolism [Protein Kinases], Cells, Cultured, Neurons, ultrastructure [Neurons], biology, General Neuroscience, drug effects [Mitochondria], Articles, Mitochondria, Cell biology, Protein Transport, metabolism [L-Lactate Dehydrogenase], drug effects [Microtubules], drug effects [Protein Transport], pharmacology [Peptide Fragments], metabolism [Neurofilament Proteins], Neurofilament, Dendritic Spines, metabolism [Microtubules], Tau protein, tau Proteins, Microscopy, Electron, Transmission, drug effects [Phosphorylation], Microtubule, Animals, drug effects [Neurons], ddc:610, Analysis of Variance, Amyloid beta-Peptides, L-Lactate Dehydrogenase, Cyclin-dependent kinase 5, Dendrites, Embryo, Mammalian, metabolism [tau Proteins], Peptide Fragments, Rats, Somatodendritic compartment, Tubulin, metabolism [Adenosine Triphosphate], pharmacology [Amyloid beta-Peptides], cytology [Hippocampus], biology.protein, Calcium, chemistry [Amyloid beta-Peptides], Protein Kinases

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b12428219a7b11d2216bc163cd02f53eTest
https://doi.org/10.1523/jneurosci.2357-10.2010Test

المؤلفون: Georg A. Sprenger, Thomas Wiegert, Roland Freudl, Natascha Blaudeck

المصدر: Journal of bacteriology 183, 604-610 (2001). doi:10.1128/JB.183.2.604-610.2001

مصطلحات موضوعية: metabolism [Recombinant Fusion Proteins], Signal peptide, Carbonyl Cyanide m-Chlorophenyl Hydrazone, pharmacology [Carbonyl Cyanide m-Chlorophenyl Hydrazone], Recombinant Fusion Proteins, metabolism [Oxidoreductases, N-Demethylating], glucose-fructose oxidoreductase, Molecular Sequence Data, Genetics and Molecular Biology, Protein Sorting Signals, Biology, Arginine, Microbiology, Twin-arginine translocation pathway, Species Specificity, ddc:570, Escherichia coli, Amino Acid Sequence, Protein Precursors, metabolism [Protein Precursors], Sodium Azide, Molecular Biology, Peptide sequence, Zymomonas, Cofactor binding, metabolism [Zymomonas], Oxidoreductases, N-Demethylating, Periplasmic space, metabolism [Periplasm], Translocon, Fusion protein, Transport protein, Protein Transport, Biochemistry, drug effects [Protein Transport], Periplasm, pharmacology [Sodium Azide], metabolism [Escherichia coli], trimethylamine dehydrogenase, Oxidoreductases, metabolism [Oxidoreductases]

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f18ebf710111092c110dcac25d0e26bbTest
https://doi.org/10.1128/jb.183.2.604-610.2001Test

المؤلفون: Kwiatkowska, A., Kijewska, M., Lipko, M., Hibner, U., Kaminska, B.

المساهمون: Institut de Génétique Moléculaire de Montpellier (IGMM), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)

المصدر: ISSN: 0167-4889 ; Biochimica et Biophysica Acta - Molecular Cell Research ; https://hal.science/hal-02193320Test ; Biochimica et Biophysica Acta - Molecular Cell Research, 2011, 1813 (5), pp.655--67. ⟨10.1016/j.bbamcr.2011.01.020⟩.

مصطلحات موضوعية: Genetic/drug effects, Actins/metabolism Animals Cell Line, Tumor Cell Movement/drug effects Cell Shape/drug effects Cyclosporine/pharmacology *Down-Regulation/drug effects Focal Adhesion Kinase 1/*metabolism Glioblastoma/*enzymology/pathology Humans Matrix Metalloproteinase 14/*metabolism Matrix Metalloproteinase 2/*metabolism Mice NF-kappa B/genetics Neoplasm Invasiveness Phosphatidylinositol 3-Kinases/antagonists & inhibitors/metabolism Phosphorylation/drug effects Protein Transport/drug effects Proto-Oncogene Proteins c-akt/antagonists & inhibitors/*metabolism Pseudopodia/drug effects/*enzymology Signal Transduction/drug effects Transcription, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology

العلاقة: hal-02193320; https://hal.science/hal-02193320Test

الإتاحة: https://doi.org/10.1016/j.bbamcr.2011.01.020Test
https://hal.science/hal-02193320Test

المؤلفون: Duitman, Erwin H., Orinska, Zane, Bulanova, Elena, Paus, Ralf, Bulfone-Paus, Silvia

المصدر: Duitman , E H , Orinska , Z , Bulanova , E , Paus , R & Bulfone-Paus , S 2008 , ' How a cytokine is chaperoned through the secretory pathway by complexing with its own receptor: Lessons from interleukin-15 (IL-15)/IL-15 receptor ' , Molecular and Cellular Biology , vol. 28 , no. 15 , pp. 4851-4861 . https://doi.org/10.1128/MCB.02178-07Test

مصطلحات موضوعية: Animals, Cell Line, drug effects: Cell Membrane, pharmacology: Dipeptides, metabolism: Endonucleases, drug effects: Endoplasmic Reticulum, Humans, pharmacology: Interferon-gamma, secretion: Interleukin-15, metabolism: Interleukin-15 Receptor alpha Subunit, drug effects: Intracellular Space, drug effects: Macrophages, Models, Biological, metabolism: Molecular Chaperones, drug effects: Monocytes, metabolism: Peptide Hydrolases, drug effects: Protein Transport

الإتاحة: https://doi.org/10.1128/MCB.02178-07Test
https://research.manchester.ac.uk/en/publications/7030627d-2efe-4c89-b3c5-d4e7996422e6Test

المؤلفون: Rossana Foti, Cristina Bellarosa, Raffaella Calligaris, H Krmac, Pablo J. Giraudi, Paola Roncaglia, Stefano Gustincich, Claudio Tiribelli

المساهمون: Calligaris, R, Bellarosa, C, Foti, R, Roncaglia, P, Giraudi, P, Krmac, H, Tiribelli, Claudio, Gustincich, S.

المصدر: BMC Genomics
BMC Genomics, Vol 10, Iss 1, p 543 (2009)

مصطلحات موضوعية: X-Box Binding Protein 1, metabolism, Autophagy, SH-SY5Y, Transcription, Genetic, chemistry/pharmacology, pathology, Neuron, Endoplasmic Reticulum, metabolism, Endoplasmic Reticulum, Transcriptome, Neuroblastoma, drug effects/genetics, Bilirubin, Homeostasis, Amino Acids, chemistry/pharmacology, Cell Line, Tumor, Cell Survival, drug effects, DNA-Binding Proteins, drug effects/genetics/metabolism, Gene Expression Profiling, Homeostasis, drug effects, Humans, Neuroblastoma, pathology, Neurons, drug effects/metabolism/pathology, Oligonucleotide Array Sequence Analysis, Protein Biosynthesis, drug effects/genetics, Protein Splicing, drug effects, Protein Transport, drug effects/genetics, Reproducibility of Results, Reverse Transcriptase Polymerase Chain Reaction, Transcription Factor CHOP, metabolism, Transcription Factors, metabolism, Transcription, Genetic, drug effects, Unfolded Protein Response, drug effects, Oligonucleotide Array Sequence Analysis, Neurons, Tumor, Reverse Transcriptase Polymerase Chain Reaction, drug effects/genetics, drug effects/metabolism/pathology, Cell biology, DNA-Binding Proteins, Amino Acid, Protein Transport, Transcription, Intracellular, Biotechnology, XBP1, lcsh:QH426-470, Cell Survival, lcsh:Biotechnology, Regulatory Factor X Transcription Factors, Biology, Cell Line, lcsh:TP248.13-248.65, Cell Line, Tumor, Research article, drug effects/metabolism/pathology, Oligonucleotide Array Sequence Analysis, Protein Biosynthesi, Autophagy, Genetics, Humans, Protein Splicing, drug effects, DNA-Binding Protein, Gene Expression Profiling, Endoplasmic reticulum, Reproducibility of Results, Bilirubin, Subcellular localization, Molecular biology, Gene expression profiling, lcsh:Genetics, Protein Biosynthesis, Unfolded Protein Response, Unfolded protein response, drug effects/genetics/metabolism, pathology, drug effects/genetics/metabolism, Gene Expression Profiling, Homeostasi, metabolism, metabolism, Transcription Factor, Transcription Factor CHOP, Transcription Factors

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f51a510d1d37bcd14aa0ae175580f810Test
https://doi.org/10.1186/1471-2164-10-543Test