المؤلفون: Pauline Morigny, Doris Kaltenecker, Julia Zuber, Juliano Machado, Lisa Mehr, Foivos‐Filippos Tsokanos, Hanna Kuzi, Chris D. Hermann, Michael Voelkl, German Monogarov, Christoph Springfeld, Victor Laurent, Bernd Engelmann, Helmut Friess, Inka Zörnig, Achim Krüger, Jeroen Krijgsveld, Olga Prokopchuk, Søren Fisker Schmidt, Maria Rohm, Stephan Herzig, Mauricio Berriel Diaz

المصدر: Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 5, Pp 1333-1351 (2021)

مصطلحات موضوعية: Cancer cachexia, PLA2G7, Mouse models, Cancer patients, Darapladib, Biomarker, Diseases of the musculoskeletal system, RC925-935, Human anatomy, QM1-695

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2190-5991Test; https://doaj.org/toc/2190-6009Test

الوصول الحر: https://doaj.org/article/7b8d070d96e44d258b9018906027d16eTest

المؤلفون: Wihastuti TA, Aini FN, Tjahjono CT, Sulfia YH, Sholichah Z, Heriansyah T

المصدر: Vascular Health and Risk Management, Vol Volume 15, Pp 503-508 (2019)

مصطلحات موضوعية: il-1b- type cytokine, il-6- type cytokine, kidney organ, diabetes melitus type 2, darapladib, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

العلاقة: https://www.dovepress.com/lp-pla2-selective-inhibitorTest-darapladib-effect-in-lowering-the-expressi-peer-reviewed-article-VHRM; https://doaj.org/toc/1178-2048Test

الوصول الحر: https://doaj.org/article/11fee68e123e44f483e97fc585370537Test

المؤلفون: Morigny, P., Kaltenecker, D., Zuber, J., Machado, J., Mehr, L., Tsokanos, F.-F., Kuzi, H., Hermann, C.D., Voelkl, M., Monogarov, G., Springfeld, C., Laurent, V., Engelmann, B., Friess, H., Zörnig, I., Krüger, A., Krijgsveld, J., Prokopchuk, O., Schmidt, S.F., Rohm, M., Herzig, S., Berriel Diaz, M.

المصدر: J. Cachexia Sarcopenia Muscle, DOI:10.1002/jcsm.12758 (2021)

مصطلحات موضوعية: Biomarker, Cancer Cachexia, Cancer Patients, Darapladib, Mouse Models, Pla2g7

وصف الملف: application/pdf

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/34427055; info:eu-repo/semantics/altIdentifier/wos/WOS:000687456400001; info:eu-repo/semantics/altIdentifier/isbn/2190-5991; info:eu-repo/semantics/altIden; https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=62883Test; urn:isbn:2190-5991; urn:issn:2190-5991; urn:issn:2190-6009

الإتاحة: https://doi.org/10.1002/jcsm.12758Test
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=62883Test

المؤلفون: Wihastuti Titin Andri, Heriansyah Teuku, Hanifa Hanifa, Andarini Sri, Sholichah Zuhrotus, Sulfia Yuni Hendrati, Adam Aditya Angela, Refialdinata Jeki, Lutfiana Nurul Cholifah

المصدر: Endocrine Regulations, Vol 52, Iss 2, Pp 69-75 (2018)

مصطلحات موضوعية: darapladib, atherosclerosis, type 2 diabetes mellitus rat model, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1336-0329Test

الوصول الحر: https://doaj.org/article/f86c69e1ff364b888452bae779ae9e01Test

المؤلفون: Teuku Heriansyah, Aditya Angela Adam, Titin Andri Wihastuti, Mohammad Saifur Rohman

المصدر: Asian Pacific Journal of Tropical Biomedicine, Vol 7, Iss 2, Pp 134-138 (2017)

مصطلحات موضوعية: OxLDL, Serum, Aorta, Lp-PLA2, Darapladib, Foam cell, Arctic medicine. Tropical medicine, RC955-962, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2221169116300983Test; https://doaj.org/toc/2221-1691Test

الوصول الحر: https://doaj.org/article/ad67c055c1d4413f8b9e93c1941065c5Test

المؤلفون: A. Delage

المصدر: Douleur et Analgésie. 34:195-198

مصطلحات موضوعية: chemistry.chemical_classification, Reactive oxygen species, medicine.medical_specialty, business.industry, medicine.disease, Pathophysiology, chemistry.chemical_compound, Anesthesiology and Pain Medicine, Lysophosphatidylcholine, Endocrinology, chemistry, Fibromyalgia, Darapladib, Internal medicine, Hyperalgesia, Nociceptor, Medicine, Biomarker (medicine), medicine.symptom, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::28924b2dae7bcd12e979406f97944d9bTest
https://doi.org/10.3166/dea-2021-0169Test

المؤلفون: Mauricio Berriel Diaz, Helmut Friess, Lisa Mehr, Maria Rohm, Michael Voelkl, Julia Zuber, Bernd Engelmann, Inka Zörnig, Søren Fisker Schmidt, Christoph Springfeld, Olga Prokopchuk, Foivos-Filippos Tsokanos, Hanna Kuzi, Pauline Morigny, Doris Kaltenecker, Jeroen Krijgsveld, Victor Laurent, Achim Krüger, Juliano Machado, German Monogarov, Chris D. Hermann, Stephan Herzig

المصدر: J. Cachexia Sarcopenia Muscle, DOI: 10.1002/jcsm.12758 (2021)
Journal of Cachexia, Sarcopenia and Muscle
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 5, Pp 1333-1351 (2021)

مصطلحات موضوعية: Oncology, medicine.medical_specialty, Cachexia, Inflammation, Diseases of the musculoskeletal system, Mouse models, Systemic inflammation, PLA2G7, Mice, Physiology (medical), Internal medicine, Darapladib, Pancreatic cancer, Oximes, medicine, Animals, Humans, Orthopedics and Sports Medicine, Prospective Studies, Wasting, business.industry, QM1-695, Cancer, Cancer cachexia, Cancer patients, Original Articles, Biomarker, medicine.disease, Pancreatic Neoplasms, RC925-935, Benzaldehydes, Human anatomy, 1-Alkyl-2-acetylglycerophosphocholine Esterase, Cancer Cachexia, Cancer Patients, Mouse Models, Pla2g7, Biomarker (medicine), Original Article, medicine.symptom, business, Biomarkers

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24de913b366aa3702551914ffe2ca9afTest
https://doi.org/10.1002/jcsm.12758Test

المؤلفون: Gregson, John M., Freitag, Daniel F., Surendran, Praveen, Stitziel, Nathan O., Chowdhury, Rajiv, Burgess, Stephen, Kaptoge, Stephen, Gao, Pei, Staley, James R., Willeit, Peter, Nielsen, Sune F., Caslake, Muriel, Trompet, Stella, Polfus, Linda M., Kuulasmaa, Kari, Kontto, Jukka, Perola, Markus, Blankenberg, Stefan, Veronesi, Giovanni, Gianfagna, Francesco, Mannisto, Satu, Kimura, Akinori, Lin, Honghuang, Reilly, Dermot F., Gorski, Mathias, Mijatovic, Vladan, Munroe, Patricia B., Ehret, Georg B., Thompson, Alex, Uria-Nickelsen, Maria, Malarstig, Anders, Dehghan, Abbas, Vogt, Thomas F., Sasaoka, Taishi, Takeuchi, Fumihiko, Kato, Norihiro, Yamada, Yoshiji, Kee, Frank, Mueller-Nurasyid, Martina, Ferrieres, Jean, Arveiler, Dominique, Amouyel, Philippe, Salomaa, Veikko, Boerwinkle, Eric, Thompson, Simon G., Ford, Ian, Jukema, J. Wouter, Sattar, Naveed, Packard, Chris J., Majumder, Abdulla al Shafi, CKDGen Consortium, Int Consortium Blood Pressure, CHARGE Inflammation Working Grp, MICAD Exome Consortium, EPIC-CVD Consortium, CHD Exome Consortium

المساهمون: Institute for Molecular Medicine Finland, University of Helsinki, Quantitative Genetics

مصطلحات موضوعية: Human genetics, target validation, coronary heart disease, lipoprotein-associated phospholipase A(2), darapladib, CORONARY-HEART-DISEASE, ACTIVATING-FACTOR ACETYLHYDROLASE, PHOSPHOLIPASE A(2) ACTIVITY, GENOME-WIDE ASSOCIATION, CARDIOVASCULAR-DISEASE, ARTERY-DISEASE, RISK, VARIANTS, EVENTS, Biomedicine, Genetics, developmental biology, physiology, General medicine, internal medicine and other clinical medicine

وصف الملف: application/pdf

العلاقة: The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The work of the coordinating centre was funded by the UK Medical Research Council (G0800270), British Heart Foundation (SP/09/002), British Heart Foundation Cambridge Cardiovascular Centre of Excellence, UK National Institute for Health Research Cambridge Biomedical Research Centre, European Research Council (268834), European Commission Framework Programme 7 (HEALTH-F2-2012-279233). The Supplement includes a list provided by investigators of some of the funders of the component studies in this analysis.; Gregson , J M , Freitag , D F , Surendran , P , Stitziel , N O , Chowdhury , R , Burgess , S , Kaptoge , S , Gao , P , Staley , J R , Willeit , P , Nielsen , S F , Caslake , M , Trompet , S , Polfus , L M , Kuulasmaa , K , Kontto , J , Perola , M , Blankenberg , S , Veronesi , G , Gianfagna , F , Mannisto , S , Kimura , A , Lin , H , Reilly , D F , Gorski , M , Mijatovic , V , Munroe , P B , Ehret , G B , Thompson , A , Uria-Nickelsen , M , Malarstig , A , Dehghan , A , Vogt , T F , Sasaoka , T , Takeuchi , F , Kato , N , Yamada , Y , Kee , F , Mueller-Nurasyid , M , Ferrieres , J , Arveiler , D , Amouyel , P , Salomaa , V , Boerwinkle , E , Thompson , S G , Ford , I , Jukema , J W , Sattar , N , Packard , C J , Majumder , A A S , CKDGen Consortium , Int Consortium Blood Pressure , CHARGE Inflammation Working Grp , MICAD Exome Consortium , EPIC-CVD Consortium & CHD Exome Consortium 2017 , ' Genetic invalidation of Lp-PLA(2) as a therapeutic target : Large-scale study of five functional Lp-PLA(2)-lowering alleles ' , European journal of preventive cardiology , vol. 24 , no. 5 , pp. 492-504 . https://doi.org/10.1177/2047487316682186Test; http://hdl.handle.net/10138/231885Test; 5ae9ed0e-c2f2-4796-a474-a442353a47dd; 85014459877; 000397434800006

الإتاحة: http://hdl.handle.net/10138/231885Test

المؤلفون: Maciej Banach, Jure Tršan, Zlatko Fras

المصدر: Archives of Medical Science. 17:954-964

مصطلحات موضوعية: biology, business.industry, Vascular inflammation, General Medicine, Disease, Phospholipase, Bioinformatics, Clinical trial, chemistry.chemical_compound, Phospholipase A2, chemistry, Darapladib, biology.protein, Medicine, Biomarker (medicine), Varespladib, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::229a65e00591802c8f6f22d45dbd4ea1Test
https://doi.org/10.5114/aoms.2020.98195Test

المؤلفون: Rixin Zhang, Min Yang, Weiqi Wang, Zifan Zeng, Wenqiang Gan, Tiegang Li, Yufang Hou, Silin Lv, Zheng Yan

المصدر: Acta Pharmacol Sin

مصطلحات موضوعية: Male, Cardiotonic Agents, Inflammasomes, Cardiac fibrosis, Anti-Inflammatory Agents, Cardiomegaly, Inflammation, Pharmacology, Article, Fibrosis, Darapladib, NLR Family, Pyrin Domain-Containing 3 Protein, Oximes, medicine, Animals, Macrophage, Pharmacology (medical), Enzyme Inhibitors, business.industry, Angiotensin II, Macrophages, Interleukin, Heart, Inflammasome, General Medicine, medicine.disease, Mice, Inbred C57BL, Benzaldehydes, 1-Alkyl-2-acetylglycerophosphocholine Esterase, medicine.symptom, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddf40fc13411cbbbfbce935ad4e395abTest
https://doi.org/10.1038/s41401-021-00703-7Test