دورية أكاديمية
Postoperative blood loss reduction in computer-assisted surgery total knee replacement by low dose intra-articular tranexamic acid injection together with 2-hour clamp drain: a prospective triple-blinded randomized controlled trial
| العنوان: | Postoperative blood loss reduction in computer-assisted surgery total knee replacement by low dose intra-articular tranexamic acid injection together with 2-hour clamp drain: a prospective triple-blinded randomized controlled trial |
|---|---|
| المؤلفون: | Paphon Sa-ngasoongsong, Thanaphot Channoom, Viroj Kawinwonggowit, Patarawan Woratanarat, Pongsthorn Chanplakorn, Bussanee Wibulpolprasert, Siwadol Wongsak, Umaporn Udomsubpayakul, Supaporn Wechmongkolgorn, Nantaporn Lekpittaya |
| المصدر: | Orthopedic Reviews, Vol 3, Iss 2, Pp e12-e12 (2011) |
| بيانات النشر: | Open Medical Publishing, 2011. |
| سنة النشر: | 2011 |
| المجموعة: | LCC:Orthopedic surgery |
| مصطلحات موضوعية: | computer assisted surgery, total knee replacement, intra-articular, tranexamic acid, blood loss., Orthopedic surgery, RD701-811 |
| الوصف: | A high-dose local tranexamic acid has been introduced in total knee arthroplasty for bleeding control. We are not sure about the systemic absorption and side effects. The aim of this study was to evaluate the effect of low dosage of intra-articular tranexamic acid injection combined with 2-hour clamp drain in minimally bleeding computer-assisted surgery total knee replacement (CAS-TKR). A prospective randomized controlled trial was conducted in a total of 48 patients underwent CAS-TKR. The patients were randomly assigned to receive either of a mixed intra-articular solution of tranexamic acid 250 mg with physiologic saline (TXA group), or physiologic saline (control group) and then followed by clamp drain for 2 hours. Postoperative blood loss was measured by three different methods as drainage volume, total hemoglobin loss and calculated total blood loss. Transfusion requirement and postoperative complications were recorded. All patients were screened for deep vein thrombosis and the functional outcomes were evaluated at 6 months after surgery. The mean postoperative drainage volume, total hemoglobin loss and calculated total blood loss in TXA group were 308.8 mL, 2.1 g/dL and 206.3 mL compared to 529.0 mL, 3.0 g/dL and 385.1 mL in the control group (P=0.0003, 0.0005 and |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2035-8237 2035-8164 64425827 |
| العلاقة: | http://www.pagepress.org/journals/index.php/or/article/view/3225Test; https://doaj.org/toc/2035-8237Test; https://doaj.org/toc/2035-8164Test |
| DOI: | 10.4081/or.2011.e12 |
| الوصول الحر: | https://doaj.org/article/e7b64425827a4377a73ca7b40681dd9bTest |
| رقم الانضمام: | edsdoj.7b64425827a4377a73ca7b40681dd9b |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20358237 20358164 64425827 |
|---|---|
| DOI: | 10.4081/or.2011.e12 |