دورية أكاديمية
Utilizing Spontaneous Ventilation Modes in Patients Underwent Corrective Surgery for Right Ventricular Outflow Tract Obstructive Congenital Heart Disease: A Crossover Study
العنوان: | Utilizing Spontaneous Ventilation Modes in Patients Underwent Corrective Surgery for Right Ventricular Outflow Tract Obstructive Congenital Heart Disease: A Crossover Study |
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المؤلفون: | Xiaolei Gong, Limin Zhu, Mingjie Zhang, Yujie Liu, Chunxiang Li, Zhuoming Xu, Jinghao Zheng |
المصدر: | Reviews in Cardiovascular Medicine, Vol 24, Iss 5, p 143 (2023) |
بيانات النشر: | IMR Press |
سنة النشر: | 2023 |
المجموعة: | Directory of Open Access Journals: DOAJ Articles |
مصطلحات موضوعية: | congenital heart disease, mechanical ventilation, cardiac-pulmonary interaction, right ventricle outflow tract obstruction, spontaneous ventilation modes, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
الوصف: | Background: This study aimed to determine whether the hemodynamics of patients with right ventricle outflow tract obstructive congenital heart disease (RVOTO-CHD) improve after corrective surgery by changing the ventilation mode. Methods: Patients with RVOTO-CHD who underwent corrective surgery were enrolled in this study. Echocardiography and advanced hemodynamic monitoring were performed using the pulse indicator continuous cardiac output (PiCCO) technology in the pressure-regulated volume control (PRVC) mode, followed with switching to the pressure support ventilation (PSV) mode and neurally adjusted ventilatory assist (NAVA) mode in random order. Results: Overall, 31 patients were enrolled in this study from April 2021 to October 2021. Notably, changing the ventilation mode from PRVC to a spontaneous mode (PSV or NAVA) led to better cardiac function outcomes, including right ventricular cardiac index (PRVC: 3.19 ± 1.07 L/min/m2 vs. PSV: 3.45 ± 1.32 L/min/m2 vs. NAVA: 3.82 ± 1.03 L/min/m2, p < 0.05) and right ventricle contractility (tricuspid annular peak systolic velocity) (PRVC: 6.58 ± 1.40 cm/s vs. PSV: 7.03 ± 1.33 cm/s vs. NAVA: 7.94 ± 1.50 cm/s, p < 0.05), as detected via echocardiography. Moreover, in the NAVA mode, PiCCO-derived cardiac index (PRVC: 2.92 ± 0.54 L/min/m2 vs. PSV: 3.04 ± 0.56 L/min/m2 vs. NAVA: 3.20 ± 0.62 L/min/m2, p < 0.05), stroke volume index (PRVC: 20.38 ± 3.97 mL/m2 vs. PSV: 21.23 ± 4.33 mL/m2 vs. NAVA: 22.00 ± 4.33 mL/m2, p < 0.05), and global end diastolic index (PRVC: 295.74 ± 78.39 mL/m2 vs. PSV: 307.26 ± 91.18 mL/m2 vs. NAVA: 323.74 ± 102.87 mL/m2, p < 0.05) improved, whereas extravascular lung water index significantly reduced (PRVC: 16.42 ± 7.90 mL/kg vs. PSV: 15.42 ± 5.50 mL/kg vs. NAVA: 14.4 ± 4.19 mL/kg, p < 0.05). Furthermore, peak inspiratory pressure, mean airway pressure, driving pressure, and compliance of the respiratory system improved in the NAVA mode. No deaths were reported in this study. Conclusions: We found that utilizing spontaneous ... |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
تدمد: | 1530-6550 |
العلاقة: | https://www.imrpress.com/journal/RCM/24/5/10.31083/j.rcm2405143Test; https://doaj.org/toc/1530-6550Test; https://doaj.org/article/b5e1c219db1049839f885d350f1b861aTest |
DOI: | 10.31083/j.rcm2405143 |
الإتاحة: | https://doi.org/10.31083/j.rcm2405143Test https://doaj.org/article/b5e1c219db1049839f885d350f1b861aTest |
رقم الانضمام: | edsbas.BC32AC23 |
قاعدة البيانات: | BASE |
تدمد: | 15306550 |
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DOI: | 10.31083/j.rcm2405143 |