المؤلفون: Laszlo Kondacs, Priyanka Parijat, Alexander J. A. Cobb, Thomas Kampourakis

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Physiology, Pharmacology, Biotechnology, Virology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, thin filament structure, positively charged tail, positively charged residues, cardiac muscle contraction, fingolimod hydrophobic headgroup, cardiac troponin c, thin filaments acts, sp , nctnc – ctni, cardiac troponin, fingolimod derivatives, switch region, longer derivatives, contractile myofilaments, conformational change, biophysical characterization, better inhibitors

العلاقة: https://figshare.com/articles/journal_contribution/Synthesis_and_Biophysical_Characterization_of_Fingolimod_Derivatives_as_Cardiac_Troponin_Antagonists/25176766Test

الإتاحة: https://doi.org/10.1021/acsmedchemlett.3c00511.s001Test
https://figshare.com/articles/journal_contribution/Synthesis_and_Biophysical_Characterization_of_Fingolimod_Derivatives_as_Cardiac_Troponin_Antagonists/25176766Test

المؤلفون: Syed Mohammed Basheeruddin Asdaq, Abdulhakeem S. Alamri, Walaa F. Alsanie, Majid Alhomrani

المصدر: Molecules; Volume 26; Issue 17; Pages: 5137

مصطلحات موضوعية: SOD, catalase, garlic oil, diallyl disulfide, carvedilol, cardiac troponin C, IL-1β, TNF-α, IL-6, NF-b p65

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Natural Products Chemistry; https://dx.doi.org/10.3390/molecules26175137Test

الإتاحة: https://doi.org/10.3390/molecules26175137Test

المؤلفون: Maicon Landim-Vieira, Jamie R. Johnston, Weizhen Ji, Emily K. Mis, Joshua Tijerino, Michele Spencer-Manzon, Lauren Jeffries, E. Kevin Hall, David Panisello-Manterola, Mustafa K. Khokha, Engin Deniz, P. Bryant Chase, Saquib A. Lakhani, Jose Renato Pinto

المصدر: Frontiers in Physiology, Vol 10 (2020)

مصطلحات موضوعية: genetic analysis, cardiac troponin C, missense variant, dilated cardiomyopathy, TNNC1, Physiology, QP1-981

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/article/10.3389/fphys.2019.01612/fullTest; https://doaj.org/toc/1664-042XTest

الوصول الحر: https://doaj.org/article/d54c1495d9574db285c1dbf940168414Test

المؤلفون: Papp, Zoltan, Agostoni, Piergiuseppe, Alvarez, Julian, Bettex, Dominique, Bouchez, Stefan, Brito, Dulce, Cerny, Vladimir, Comin-Colet, Josep, Crespo-Leiro, Marisa G., Delgado, Juan F., Edes, Istvan, Eremenko, Alexander A., Farmakis, Dimitrios, Fedele, Francesco, Fonseca, Candida, Fruhwald, Sonja, Girardis, Massimo, Guarracino, Fabio, Harjola, Veli-Pekka, Heringlake, Matthias, Herpain, Antoine, Heunks, Leo M. A., Husebye, Tryggve, Ivancan, Visnja, Karason, Kristjan, Kaul, Sundeep, Kivikko, Matti, Kubica, Janek, Masip, Josep, Matskeplishvili, Simon, Mebazaa, Alexandre, Nieminen, Markku S., Oliva, Fabrizio, Papp, Julius G., Parissis, John, Parkhomenko, Alexander, Poder, Pentti, Poelzl, Gerhard, Reinecke, Alexander, Ricksten, Sven-Erik, Riha, Hynek, Rudiger, Alain, Sarapohja, Toni, Schwinger, Robert H. G., Toller, Wolfgang, Tritapepe, Luigi, Tschoepe, Carsten, Wikstroem, Gerhard, von Lewinski, Dirk, Vrtovec, Bojan, Pollesello, Piero

المساهمون: HUS Emergency Medicine and Services, Helsinki University Hospital Area, University of Helsinki, HUS Heart and Lung Center

مصطلحات موضوعية: acute heart failure, advanced heart failure, hemodynamics, inodilator, inotrope, neurohormone, regulatory clinical trial, DECOMPENSATED HEART-FAILURE, IMPROVES RENAL-FUNCTION, AMYOTROPHIC-LATERAL-SCLEROSIS, RIGHT-VENTRICULAR FUNCTION, CARDIAC TROPONIN-C, EXTRACORPOREAL MEMBRANE-OXYGENATION, GLOMERULAR-FILTRATION-RATE, CALCIUM SENSITIZING DRUG, CORONARY BLOOD-FLOW, ARTERY-BYPASS GRAFT, 3121 General medicine, internal medicine and other clinical medicine, 317 Pharmacy

وصف الملف: application/pdf

العلاقة: Papp , Z , Agostoni , P , Alvarez , J , Bettex , D , Bouchez , S , Brito , D , Cerny , V , Comin-Colet , J , Crespo-Leiro , M G , Delgado , J F , Edes , I , Eremenko , A A , Farmakis , D , Fedele , F , Fonseca , C , Fruhwald , S , Girardis , M , Guarracino , F , Harjola , V-P , Heringlake , M , Herpain , A , Heunks , L M A , Husebye , T , Ivancan , V , Karason , K , Kaul , S , Kivikko , M , Kubica , J , Masip , J , Matskeplishvili , S , Mebazaa , A , Nieminen , M S , Oliva , F , Papp , J G , Parissis , J , Parkhomenko , A , Poder , P , Poelzl , G , Reinecke , A , Ricksten , S-E , Riha , H , Rudiger , A , Sarapohja , T , Schwinger , R H G , Toller , W , Tritapepe , L , Tschoepe , C , Wikstroem , G , von Lewinski , D , Vrtovec , B & Pollesello , P 2020 , ' Levosimendan Efficacy and Safety : 20 Years of SIMDAX in Clinical Use ' , Journal of Cardiovascular Pharmacology , vol. 76 , no. 1 , pp. 4-22 . https://doi.org/10.1097/FJC.0000000000000859Test; a703c1f7-7d74-4e83-8cb7-df92d159b51f; http://hdl.handle.net/10138/320495Test; 000563273900002

الإتاحة: http://hdl.handle.net/10138/320495Test

المؤلفون: Jose R. Pinto, Tiago Veltri, Maicon Landim-Vieira, Michelle S. Parvatiyar, David Gonzalez-Martinez, Karissa M. Dieseldorff Jones, Clara A. Michell, David Dweck, Andrew P. Landstrom, P. Bryant Chase

المصدر: Frontiers in Physiology, Vol 8 (2017)

مصطلحات موضوعية: cardiac troponin C, hypertrophic cardiomyopathy, slow skeletal muscle, skinned fibers, myofibrillar ATPase, Physiology, QP1-981

وصف الملف: electronic resource

العلاقة: http://journal.frontiersin.org/article/10.3389/fphys.2017.00221/fullTest; https://doaj.org/toc/1664-042XTest

الوصول الحر: https://doaj.org/article/de0f01d82986440e8a1a28beedc74a76Test

المؤلفون: Vishal V. Undhad, Dhaval T. Fefar, B. M. Jivani, Hemant Gupta, Dineshbhai J. Ghodasara, Bholanath P. Joshi, Kantibhai S. Prajapati

المصدر: Veterinary World, Vol 5, Iss 8.000, Pp 508-511 (2012)

مصطلحات موضوعية: Cardiac troponin C, I and T, myocardium, cardiac biomarkers, Animal culture, SF1-1100, Veterinary medicine, SF600-1100

وصف الملف: electronic resource

العلاقة: http://www.scopemed.org/fulltextpdf.php?mno=20703Test; https://doaj.org/toc/0972-8988Test; https://doaj.org/toc/2231-0916Test

الوصول الحر: https://doaj.org/article/1f525993a34b468682300222809ba8cfTest

المؤلفون: Spuches, Anne Marie, Rayani, Kaveh, Seffernick, Justin, Li, Alison Yueh, Davis, Jonathan P., Van Petegem, Filip, Solaro, R. John, Steffen Lindert, Steffen, Tibbits, Glen F.

مصطلحات موضوعية: calcium, magnesium, human cardiac troponin C

وصف الملف: application/pdf

العلاقة: http://hdl.handle.net/10342/11063Test

الإتاحة: https://doi.org/10.1016/j.jbc.2021.100350Test
http://hdl.handle.net/10342/11063Test

المؤلفون: Liang Li, Béla Reiz, Brittney A. Klein, Thomas Kampourakis, Brian D. Sykes, Ian M. Robertson

المصدر: ACS Medicinal Chemistry Letters

مصطلحات موضوعية: Nitrile, 030204 cardiovascular system & hematology, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, levosimendan, 0302 clinical medicine, Drug Discovery, medicine, Moiety, Reactivity (chemistry), Solubility, 030304 developmental biology, Malononitrile, 0303 health sciences, Chemistry, Organic Chemistry, Biological activity, Cardiac troponin C, Levosimendan, Note, Combinatorial chemistry, 3. Good health, malononitrile, Covalent bond, reversible thioimidate bond formation, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::292e152faa4f221cd79f91c7c32f1c80Test
http://europepmc.org/articles/PMC7227049Test

المؤلفون: R. John Solaro, Alison Yueh Li, Steffen Lindert, Filip Van Petegem, Kaveh Rayani, Anne M. Spuches, Jonathan P. Davis, Glen F. Tibbits, Justin T Seffernick

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, thermodynamic integration, TF, thin filament, myofilament, Regulatory site, cTn, cardiac troponin, Biochemistry, Troponin complex, Troponin I, Magnesium, education.field_of_study, CaM, calmodulin, biology, Chemistry, ITC, isothermal titration calorimetry, Cardiac muscle, TI, thermodynamic integration, musculoskeletal system, cTnC, cardiac troponin C, medicine.anatomical_structure, Thermodynamics, sTnC, skeletal muscle troponin TnC, calorimetry, Protein Binding, Research Article, Calmodulin, Cations, Divalent, Population, contractility, cTnI, cardiac troponin I, 03 medical and health sciences, PDB, Protein Data Bank, medicine, cTnT, cardiac troponin T, Humans, education, Molecular Biology, Actin, Binding Sites, 030102 biochemistry & molecular biology, FF, fast-flow, Myocardium, Isothermal titration calorimetry, MD simulation, Cell Biology, ITC, molecular dynamics, 030104 developmental biology, Biophysics, biology.protein, Calcium, Troponin C

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28f98bcd3bdeebfd40de75f4f8c2cf35Test
https://pubmed.ncbi.nlm.nih.gov/33548225Test

المؤلفون: Reinoso, Tyler R, Landim-Vieira, Maicon, Shi, Yun, Johnston, Jamie R, Chase, P Bryant, Parvatiyar, Michelle S, Landstrom, Andrew P, Pinto, Jose R, Tadros, Hanna J

مصطلحات موضوعية: Cardiac troponin C (cTnC), Cardiomyopathy, Genetic variant, Heart, Post-translational modification, TNNC1

وصف الملف: application/pdf

العلاقة: Journal of muscle research and cell motility; https://hdl.handle.net/10161/21939Test

الإتاحة: https://doi.org/10.1007/s10974-020-09592-5Test
https://hdl.handle.net/10161/21939Test