Appropriate use of cancer comprehensive genome profiling assay using circulating tumor DNA
| العنوان: | Appropriate use of cancer comprehensive genome profiling assay using circulating tumor DNA |
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| المؤلفون: | Kuniko Sunami, Tetsu Hayashida, Kazuto Nishio, Shinji Kohsaka, Ichiro Kinoshita, Hiroyuki Uetake, Kenji Tamura, Koshi Mimori, Hideaki Takahashi, Shinichi Toyooka, Noboru Yamamoto, Hideaki Bando, Masayuki Takeda, Keigo Komine, Katsuya Tsuchihara, Yoichi Naito, Yasushi Yatabe |
| المصدر: | Cancer Science |
| بيانات النشر: | Wiley, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Oncology, Cancer Research, medicine.medical_specialty, cancer comprehensive genome profiling assay, Guidelines as Topic, Appropriate use, Japan, Report, Neoplasms, Internal medicine, Biomarkers, Tumor, medicine, Humans, Liquid biopsy, plasma, circulating tumor DNA, Blood Specimen Collection, liquid biopsy, Universal health insurance, business.industry, Task force, Gene Expression Profiling, High-Throughput Nucleotide Sequencing, Cancer, General Medicine, medicine.disease, Advice (programming), next‐generation sequencer, Circulating tumor DNA, Mutation, Genome profiling, sense organs, Transcriptome, business, Reports |
| الوصف: | Comprehensive genomic profiling (CGP) is being increasingly used for the routine clinical management of solid cancers. In July 2018, the use of tumor tissue‐based CGP assays became available for all solid cancers under the universal health insurance system in Japan. Several restrictions presently exist, such as patient eligibility and limitations on the opportunities to perform such assays. The clinical implementation of CGP based on plasma circulating tumor DNA (ctDNA) is also expected to raise issues regarding the selection and use of tissue DNA and ctDNA CGP. A Joint Task Force for the Promotion of Cancer Genome Medicine comprised of three Japanese cancer‐related societies has formulated a policy proposal for the appropriate use of plasma CGP (in Japanese), available at https://www.jca.gr.jp/researcher/topics/2021/files/20210120.pdfTest, http://www.jsco.or.jp/jpn/user_data/upload/File/20210120.pdfTest, and https://www.jsmo.or.jp/file/dl/newsj/2765.pdfTest. Based on these recommendations, the working group has summarized the respective advantages and cautions regarding the use of tissue DNA CGP and ctDNA CGP with reference to the advice of a multidisciplinary expert panel, the preferred use of plasma specimens over tissue, and multiple ctDNA testing. These recommendations have been prepared to maximize the benefits of performing CGP assays and might be applicable in other countries and regions. |
| تدمد: | 1349-7006 1347-9032 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a407ae9edae68c51f00c5b85d878b687Test https://doi.org/10.1111/cas.15022Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....a407ae9edae68c51f00c5b85d878b687 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 13497006 13479032 |
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