المؤلفون: Darshini A. Desai, Akhil Baby, Kalyani Ananthamohan, Lisa C. Green, Mohammed Arif, Brittany C. Duncan, Mohit Kumar, Rohit R. Singh, Sheryl E. Koch, Sankar Natesan, Jack Rubinstein, Anil G. Jegga, Sakthivel Sadayappan

المصدر: Journal of Molecular and Cellular Cardiology Plus, Vol 8, Iss , Pp 100075- (2024)

مصطلحات موضوعية: cMyBP-C, Diabetes, HFpEF, MYBPC3, Mavacamten, Phosphorylation, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2772976124000151Test; https://doaj.org/toc/2772-9761Test

الوصول الحر: https://doaj.org/article/dfbdc26c598344ae941d40c3723cf9bdTest

المؤلفون: Arts, Theo, Lyon, Aurore, Delhaas, Tammo, Kuster, Diederik W D, van der Velden, Jolanda, Lumens, Joost

المصدر: Arts , T , Lyon , A , Delhaas , T , Kuster , D W D , van der Velden , J & Lumens , J 2024 , ' Translating myosin-binding protein C and titin abnormalities to whole-heart function using a novel calcium-contraction coupling model ' , Journal of Molecular and Cellular Cardiology , vol. 190 , pp. 13-23 . https://doi.org/10.1016/j.yjmcc.2024.03.001Test

مصطلحات موضوعية: Calcium, Computer modeling, Mechanics, Sarcomere, Titin, cMyBP-C

العلاقة: https://cris.maastrichtuniversity.nl/en/publications/3abdeab0-b8eb-4277-b37f-da25e233c928Test

الإتاحة: https://doi.org/10.1016/j.yjmcc.2024.03.001Test
https://cris.maastrichtuniversity.nl/en/publications/3abdeab0-b8eb-4277-b37f-da25e233c928Test

المؤلفون: Bunch, T.A., Guhathakurta, P., Thompson, A.R., Lepak, V.C., Carter, A.L., Thomas, J.J., Thomas, D.D., Colson, B.A.

المساهمون: Department of Cellular & Molecular Medicine, University of Arizona

المصدر: Journal of Biological Chemistry

مصطلحات موضوعية: actin, cardiac muscle, cardiac myosin-binding protein C (cMyBP-C), contractile proteins, fluorescence lifetime (FLT), fluorescence resonance energy transfer (FRET), high-throughput screen (HTS), phosphorylation, protein kinase A (PKA), site-directed spectroscopy

العلاقة: Bunch, Thomas A., et al. "Drug discovery for heart failure targeting myosin-binding protein C." Journal of Biological Chemistry 299.12 (2023).; http://hdl.handle.net/10150/671453Test; Journal of Biological Chemistry

الإتاحة: https://doi.org/10.1016/j.jbc.2023.105369Test
http://hdl.handle.net/10150/671453Test

المؤلفون: Xiaoxu Zhou, Euy‐Myoung Jeong, Hong Liu, Bahaa Kaseer, Man Liu, Suvash Shrestha, Hafiz Imran, Kylie Kavanagh, Ning Jiang, Lori‐Ann Desimone, Feng Feng, Guangbin Shi, Go Eun Jeong, Anyu Zhou, Philip Stockwell, Samuel C. Dudley

المصدر: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 11 (2022)

مصطلحات موضوعية: cMyBP‐C, diastolic dysfunction, S‐glutathionylation, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2047-9980Test

الوصول الحر: https://doaj.org/article/20c6053ec7fc49f298fd97b7852456a7Test

المؤلفون: Kensler, Robert W., Craig, Roger, Moss, Richard L.

المساهمون: Craig Lab, Department of Radiology, Department of Cell and Developmental Biology

المصدر: Proceedings of the National Academy of Sciences of the United States of America ; 114 ; 8 ; E1355-E1364

مصطلحات موضوعية: cMyBP-C, cardiac myosin binding protein C, cardiac myosin binding protein C function, cardiac thick filament, cardiac thick filament structure, Biochemistry, Cell Biology, Cellular and Molecular Physiology

العلاقة: Link to Article in PubMed; Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):E1355-E1364. doi:10.1073/pnas.1614020114. Epub 2017 Feb 6. Link to article on publisher's site; 0027-8424 (Linking); http://hdl.handle.net/20.500.14038/40295Test; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=4102&context=oapubs&unstamped=1Test; https://escholarship.umassmed.edu/oapubs/3097Test; oapubs/3097

الإتاحة: https://doi.org/10.1073/pnas.1614020114Test
https://doi.org/20.500.14038/40295Test
https://hdl.handle.net/20.500.14038/40295Test
https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=4102&context=oapubs&unstamped=1Test
https://escholarship.umassmed.edu/oapubs/3097Test

المؤلفون: Kanassatega, Rhye-Samuel, Bunch, Thomas A, Lepak, Victoria C, Wang, Christopher, Colson, Brett A

المساهمون: Department of Cellular and Molecular Medicine, University of Arizona

المصدر: Journal of molecular and cellular cardiology ; 166 ; 116 ; 126 ; United States ; England

مصطلحات موضوعية: Biosensor, Cardiac myosin-binding protein C (cMyBP-C), fluorescence lifetime, High-throughput screening (HTS), Phosphorylation, protein kinase A (PKA), Time-resolved fluorescence resonance energy transfer (TR-FRET)

العلاقة: Kanassatega, R.-S., Bunch, T. A., Lepak, V. C., Wang, C., & Colson, B. A. (2022). Human cardiac myosin-binding protein C phosphorylation- and mutation-dependent structural dynamics monitored by time-resolved FRET. Journal of Molecular and Cellular Cardiology.; http://hdl.handle.net/10150/663882Test; Journal of molecular and cellular cardiology

الإتاحة: https://doi.org/10.1016/j.yjmcc.2022.02.005Test
http://hdl.handle.net/10150/663882Test

المؤلفون: van Dijk, Sabine J, Kooiker, Kristina Bezold, Mazzalupo, Stacy, Yang, Yuanzhang, Kostyukova, Alla S, Mustacich, Debbie J, Hoye, Elaine R, Stern, Joshua A, Kittleson, Mark D, Harris, Samantha P

المصدر: Archives of Biochemistry and Biophysics. 601(16)

مصطلحات موضوعية: Biological Sciences, Bioinformatics and Computational Biology, Heart Disease, Genetics, Cardiovascular, Aetiology, 2.1 Biological and endogenous factors, Alanine, Animals, Cardiomyopathy, Hypertrophic, Carrier Proteins, Cats, Circular Dichroism, Codon, Terminator, Haploinsufficiency, Heart, Immunohistochemistry, Muscle Cells, Mutation, Mutation, Missense, Myocardium, Proline, Protein Conformation, Protein Domains, Protein Structure, Secondary, Recombinant Proteins, Sarcomeres, cMyBP-C, Hypertrophic cardiomyopathy, Missense mutation, Animal models of cardiac disease, Biochemistry & Molecular Biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/2159w3mmTest

المؤلفون: Carmen Suay-Corredera (10904886), Maria Rosaria Pricolo (10904889), Diana Velázquez-Carreras (10904892), Divya Pathak (79579), Neha Nandwani (10904895), Carolina Pimenta-Lopes (10904898), David Sánchez-Ortiz (10904901), Iñigo Urrutia-Irazabal (10904904), Silvia Vilches (442014), Fernando Dominguez (5650558), Giulia Frisso (5222282), Lorenzo Monserrat (2622139), Pablo García-Pavía (10904907), David de Sancho (9455422), James A. Spudich (10904910), Kathleen M. Ruppel (10904913), Elías Herrero-Galán (2005204), Jorge Alegre-Cebollada (1611883)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Physiology, Developmental Biology, Cancer, Computational Biology, Biological Sciences not elsewhere classified, Physical Sciences not elsewhere classified, cMyBP-C mutations, results show, nanomechanical phenotypes, 40 pN, Cause Hypertrophic Cardiomyopathy H., mutations cause, mutation R 495W, motor myosin, Cardiac Myosin-Binding Protein C Mu., actomyosin filaments, R 502Q, HCM mutations, protein structure, RNA, myosin-binding protein C, mutations perturb, nonpathogenic variants, cMyBP-C domains

العلاقة: https://figshare.com/articles/journal_contribution/Nanomechanical_Phenotypes_in_Cardiac_Myosin-Binding_Protein_C_Mutants_That_Cause_Hypertrophic_Cardiomyopathy/14711091Test

الإتاحة: https://doi.org/10.1021/acsnano.1c02242.s001Test

المؤلفون: Ya-Li Sun, Muhammad Nabeel Dookhun, Xin-Zheng Lu

المصدر: Cardiology Plus, Vol 4, Iss 4, Pp 111-115 (2019)

مصطلحات موضوعية: myocardial myosin-binding protein c, cmybp-c, dilated cardiomyopathy, hypertension, left ventricular enlargement, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

العلاقة: http://www.cardiologyplus.org/article.asp?issn=2470-7511;year=2019;volume=4;issue=4;spage=111;epage=115;aulast=SunTest; https://doaj.org/toc/2470-7511Test; https://doaj.org/toc/2470-752XTest

الوصول الحر: https://doaj.org/article/bfa41c81990741a38ec9400a6c52b9aaTest

المؤلفون: Matsuyama, Sho, Kage, Yohko, Fujimoto, Noriko, Ushijima, Tomoki, Tsuruda, Toshihiro, Kitamura, Kazuo, Shiose, Akira, Asada, Yujiro, Sumimoto, Hideki, Takeya, Ryu

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2018 May 01. 115(19), E4386-E4395.

الوصول الحر: https://www.jstor.org/stable/26509608Test