المؤلفون: Magdalena Strachowska, Karolina Gronkowska, Maciej Sobczak, Marika Grodzicka, Sylwia Michlewska, Kinga Kołacz, Tuhin Sarkar, Joanna Korszun, Maksim Ionov, Agnieszka Robaszkiewicz

المصدر: Biomedicine & Pharmacotherapy, Vol 168, Iss , Pp 115798- (2023)

مصطلحات موضوعية: CREB-binding protein/Histone acetyltransferase p300 (CBP/EP300) bromodomain inhibitor, Multi-drug resistance (MDR), ATP-binding cassette transporters (ABC), Triple-negative breast cancer, Non-small cell lung cancer, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S0753332223015962Test; https://doaj.org/toc/0753-3322Test

الوصول الحر: https://doaj.org/article/69462619b8e54a91966e2966d4016c5dTest

المؤلفون: Banham, Gemma

المساهمون: Clatworthy, Menna

مصطلحات موضوعية: 616.07, B cell, IgG, BLyS, Transplantation, Immunosuppression, Belimumab, Alloimmune, Bromodomain inhibitor, Mononuclear phagocytes, Fc gamma receptors

الوصول الحر: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.763813Test

المؤلفون: Soumen Barman, Snehasudha Subhadarsini Sahoo, Jyotirmayee Padhan, Babu Sudhamalla

مصطلحات موضوعية: Biophysics, Biochemistry, Molecular Biology, Pharmacology, Immunology, Cancer, Hematology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, PTM, BRD4, bromodomain inhibitor, HTVS, natural product, acetyllysine

العلاقة: https://figshare.com/articles/journal_contribution/Identification_of_novel_natural_product_inhibitors_of_BRD4_using_high_throughput_virtual_screening_and_MD_simulation/24533283Test

الإتاحة: https://doi.org/10.6084/m9.figshare.24533283.v1Test
https://figshare.com/articles/journal_contribution/Identification_of_novel_natural_product_inhibitors_of_BRD4_using_high_throughput_virtual_screening_and_MD_simulation/24533283Test

المؤلفون: Urbanucci, Alfonso, Barfeld, Stefan J, Kytölä, Ville, Itkonen, Harri M, Coleman, Ilsa M, Vodák, Daniel, Sjöblom, Liisa, Sheng, Xia, Tolonen, Teemu, Minner, Sarah, Burdelski, Christoph, Kivinummi, Kati K, Kohvakka, Annika, Kregel, Steven, Takhar, Mandeep, Alshalalfa, Mohammed, Davicioni, Elai, Erho, Nicholas, Lloyd, Paul, Karnes, R Jeffrey, Ross, Ashley E, Schaeffer, Edward M, Griend, Donald J Vander, Knapp, Stefan, Corey, Eva, Feng, Felix Y, Nelson, Peter S, Saatcioglu, Fahri, Knudsen, Karen E, Tammela, Teuvo LJ, Sauter, Guido, Schlomm, Thorsten, Nykter, Matti, Visakorpi, Tapio, Mills, Ian G

المصدر: Cell Reports. 19(10)

مصطلحات موضوعية: Biological Sciences, Urologic Diseases, Prostate Cancer, Aging, Genetics, Cancer, 2.1 Biological and endogenous factors, Aetiology, ATPases Associated with Diverse Cellular Activities, Chromatin, Chromatin Assembly and Disassembly, DNA-Binding Proteins, Gene Expression Regulation, Neoplastic, Humans, Male, Neoplasm Proteins, Prostatic Neoplasms, Castration-Resistant, Protein Serine-Threonine Kinases, Receptors, Androgen, Transcription Factors, ATAD2, BRD2, BRD4, BROMO-10, androgen receptor, bromodomain inhibitor, castration-resistant prostate cancer, chromatin, Biochemistry and Cell Biology, Medical Physiology, Biological sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/4nf0z2d0Test

المؤلفون: Lespinasse, Marie‐ange, Wei, Kaiyao, Perrin, Justine, Winkler, Matthias, Hamaidia, Sieme, Leroy, Alexis, Macek Jilkova, Zuzana, Philouze, Christian, Marche, Patrice, Petosa, Carlo, Govin, Jérôme, Emadali, Anouk, Wong, Yung‐sing

المساهمون: Département de pharmacochimie moléculaire (DPM), Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (IAB), Centre Hospitalier Universitaire CHU Grenoble (CHUGA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Etablissement français du sang - Auvergne-Rhône-Alpes (EFS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), Institut de biologie structurale (IBS - UMR 5075), Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes (UGA), Centre Hospitalier Universitaire CHU Grenoble (CHUGA), Département de Chimie Moléculaire (DCM), Labex Arcane, ANR-17-EURE-0003,CBH-EUR-GS,CBH-EUR-GS(2017), ANR-18-CE18-0007,InhiBET,Développement de nouvelles molécules antifongiques ciblant les protéines BET(2018)

المصدر: ISSN: 0947-6539.

مصطلحات موضوعية: anti-inflammatory agent, za-ortho-quinone methide, BET bromodomain inhibitor, organocatalysis, tetrahydroquinoline, [CHIM.ORGA]Chemical Sciences/Organic chemistry, [CHIM.THER]Chemical Sciences/Medicinal Chemistry

العلاقة: hal-03806738; https://hal.science/hal-03806738Test; https://hal.science/hal-03806738/documentTest; https://hal.science/hal-03806738/file/Manuscript-HAL.pdfTest

الإتاحة: https://doi.org/10.1002/chem.202202293Test
https://hal.science/hal-03806738Test
https://hal.science/hal-03806738/documentTest
https://hal.science/hal-03806738/file/Manuscript-HAL.pdfTest

المؤلفون: Ye Feng, Haider Mahdi, Richard Piekarz, Jan H Beumer, Timothy W Synold

مصطلحات موضوعية: Analytical biochemistry, assay, BET bromodomain inhibitor, chromatography, clinical, LC–MS, mass spectrometry, ZEN-3694, ZEN-3791

العلاقة: https://figshare.com/articles/dataset/An_LC_MS_MS_method_for_determination_ofthe_bromodomain_inhibitor_ZEN-3694_and_itsmetabolite_ZEN-3791_in_human_plasma_supplementary_data/25429174Test

الإتاحة: https://doi.org/10.25402/bio.25429174.v1Test

المؤلفون: Tianbang Wu, Qiuping Xiang, Chao Wang, Chun Wu, Zhao-xuan Liu, Yong Xu, Lin-jiu Xiao, Yan Zhang

مصطلحات موضوعية: BRD4, Y06014, androgen receptor, bromodomain inhibitor, prostate cancer

العلاقة: http://www.doi.org/10.1038/s41401-021-00614-7Test

الإتاحة: https://doi.org/10.57760/sciencedb.15074Test
https://doi.org/10.1038/s41401-021-00614-7Test

المؤلفون: Fu, Wenxian, Farache, Julia, Clardy, Susan M, Hattori, Kimie, Mander, Palwinder, Lee, Kevin, Rioja, Inmaculada, Weissleder, Ralph, Prinjha, Rab K, Benoist, Christophe, Mathis, Diane

المصدر: eLife. 3(November)

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Monocytes, Macrophages, Animals, Mice, Inbred NOD, Diabetes Mellitus, Type 1, Inflammation, NF-kappa B, Regeneration, Signal Transduction, Transcription, Genetic, Epigenesis, Genetic, Phenotype, Female, Insulin-Secreting Cells, Heterocyclic Compounds, 4 or More Rings, NF-KB, autoimmune diabetes, bromodomain inhibitor, immunology, mouse, Mice, Inbred NOD, Diabetes Mellitus, Type 1, Transcription, Genetic, Epigenesis, Heterocyclic Compounds, or More Rings, Biochemistry and Cell Biology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/41v808h6Test

المؤلفون: Strachowska, Magdalena, Gronkowska, Karolina, Robaszkiewicz, Agnieszka, Michlewska, Sylwia

المساهمون: Department of General Biophysics, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/143, 90-236 Lodz, Poland, Laboratory of Microscopic Imaging and Specialized Biological Techniques, Faculty of Biology and Environmental Protection, University of Lodz, Banacha 12/16, 90-237 Lodz, Poland

مصطلحات موضوعية: I-CBP112, CBP/p300 bromodomain inhibitor, ATP-binding cassette transporters (ABC), lysine-specific demethylase 1A (LSD1), histone modifications, anticancer drugs

وصف الملف: application/pdf

العلاقة: Cancers;13(18); 4614; Strachowska, M.; Gronkowska, K.; Michlewska, S.; Robaszkiewicz, A. CBP/p300 Bromodomain Inhibitor–I–CBP112 Declines Transcription of the Key ABC Transporters and Sensitizes Cancer Cells to Chemotherapy Drugs. Cancers 2021, 13, 4614. https://doi.org/10.3390/cancers13184614Test; http://hdl.handle.net/11089/39511Test

الإتاحة: https://doi.org/10.3390/cancers13184614Test
http://hdl.handle.net/11089/39511Test

المؤلفون: Hlushchuk, Irena, Ruskoaho, Heikki, Domanskyi, Andrii, Airavaara, Mikko, Välimäki, Mika J.

المساهمون: Division of Pharmacology and Pharmacotherapy, Drug Research Program, Regenerative pharmacology group, Institute of Biotechnology, Biosciences, Divisions of Faculty of Pharmacy, Neuroscience Center

مصطلحات موضوعية: alpha-Synuclein, lysine acetyltransferase, bromodomain, Parkinson's disease, CBP, p300, BROMODOMAIN INHIBITOR, DISEASE, PROTEIN, 1182 Biochemistry, cell and molecular biology

وصف الملف: application/pdf

العلاقة: We thank Robert Leigh for language editing. This work was supported by Business Finland (3iRegeneration, project 40395/13), the Finnish Foundation for Cardiovascular Research, the Academy of Finland (grants #293392, #319195), the Jane and Aatos Erkko Foundation, the Paivikki and Sakari Sohlberg Foundation, and the Sigrid Juselius Foundation.; Hlushchuk , I , Ruskoaho , H , Domanskyi , A , Airavaara , M & Välimäki , M J 2021 , ' Domain-Independent Inhibition of CBP/p300 Attenuates alpha-Synuclein Aggregation ' , ACS chemical neuroscience , vol. 12 , no. 13 , pp. 2273-2279 . https://doi.org/10.1021/acschemneuro.1c00215Test; ORCID: /0000-0002-2026-1609/work/98019667; ORCID: /0000-0002-9687-8197/work/98020491; ORCID: /0000-0001-8971-1359/work/98020581; ORCID: /0000-0002-1055-7414/work/127010291; 66a410e8-29ad-4275-b322-545cfc47b4f0; http://hdl.handle.net/10138/332776Test; 000672585800004

الإتاحة: http://hdl.handle.net/10138/332776Test