دورية أكاديمية
Enhanced “Electronic Tongue” for Dental Bacterial Discrimination and Elimination Based on a DNA-Encoded Nanozyme Sensor Array
| العنوان: | Enhanced “Electronic Tongue” for Dental Bacterial Discrimination and Elimination Based on a DNA-Encoded Nanozyme Sensor Array |
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| المؤلفون: | Ling Zhang, Zhengnan Qi, Yichi Yang, Na Lu, Zisheng Tang |
| سنة النشر: | 2024 |
| مصطلحات موضوعية: | Medicine, Microbiology, Ecology, Infectious Diseases, Space Science, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, utilizing differential interactions, second leading cause, linear discriminant analysis, artificial saliva samples, demonstrating great potential, dental bacterial discrimination, bacterial discrimination, great importance, rapid discrimination, bacterial mixtures, dental bacteria, survival rate, successfully identified, sensor array, sensing strategy, sensing elements, quantitative determination, precise differentiation, lda ), delayed treatment, death around, clinical prophylaxis |
| الوصف: | Bacterial infections are the second leading cause of death around the world, especially those caused by delayed treatment and misdiagnosis. Therefore, rapid discrimination and effective elimination of multiple bacteria are of great importance for improving the survival rate in clinic. Herein, a novel colorimetric sensor array for bacterial discrimination and elimination is constructed using programmable DNA-encoded iron oxide nanoparticles (IONPs) as sensing elements. Utilizing differential interactions of bacteria on DNA-encoded IONPs, 11 kinds of dental bacteria and 6 kinds of proteins have been successfully identified by linear discriminant analysis (LDA). Moreover, the developed sensing system also performs well in the quantitative determination of individual bacteria and identification of bacterial mixtures. More importantly, the practicability of this sensing strategy is further verified by precise differentiation of blind and artificial saliva samples. Furthermore, the sensor array is used for efficiently killing multiple bacteria, demonstrating great potential in clinical prophylaxis and therapy. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | unknown |
| العلاقة: | https://figshare.com/articles/journal_contribution/Enhanced_Electronic_Tongue_for_Dental_Bacterial_Discrimination_and_Elimination_Based_on_a_DNA-Encoded_Nanozyme_Sensor_Array/25285228Test |
| DOI: | 10.1021/acsami.3c17134.s001 |
| الإتاحة: | https://doi.org/10.1021/acsami.3c17134.s001Test https://figshare.com/articles/journal_contribution/Enhanced_Electronic_Tongue_for_Dental_Bacterial_Discrimination_and_Elimination_Based_on_a_DNA-Encoded_Nanozyme_Sensor_Array/25285228Test |
| حقوق: | CC BY-NC 4.0 |
| رقم الانضمام: | edsbas.AFF2AA66 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1021/acsami.3c17134.s001 |
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