المؤلفون: Zhong, Xueying, Kumar, R., Wang, Y., Biverstål, H., Jegerschöld, Caroline, Koeck, Philip J. B., Johansson, J., Abelein, A., Chen, G.

المصدر: ACS Chemical Biology. 17(8):2201-2211

مصطلحات موضوعية: Alzheimer, amyloid-β peptide, Arctic, Bri2 BRICHOS, amyloid, amyloid beta protein[1-42], bri2 protein, chaperone, monomer, oligomer, protein, recombinant protein, thioflavine, unclassified drug, amyloid beta protein, peptide, peptide fragment, peptide I, receptor for activated C kinase, Alzheimer disease, amino acid sequence, Article, brichos domain, fluorescence intensity, gene mutation, kinetics, neurotoxicity, protein aggregation, protein domain, chemistry, human, metabolism, Amyloid beta-Peptides, Humans, Molecular Chaperones, Peptide Fragments, Peptides, Receptors for Activated C Kinase

وصف الملف: print

الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-326796Test
https://doi.org/10.1021/acschembio.2c00344Test

المؤلفون: Makhaeva, G. F., Kovaleva, N. V., Rudakova, E. V., Boltneva, N. P., Grishchenko, M. V., Lushchekina, S. V., Astakhova, T. Y., Serebryakova, O. G., Timokhina, E. N., Zhilina, E. F., Shchegolkov, E. V., Ulitko, M. V., Radchenko, E. V., Palyulin, V. A., Burgart, Y. V., Saloutin, V. I., Bachurin, S. O., Richardson, R. J.

المصدر: International Journal of Molecular Sciences

مصطلحات موضوعية: ACETYLCHOLINESTERASE, ADMET PREDICTION, ALZHEIMER’S DISEASE, ANTIOXIDANT ACTIVITY, AΒ42 SELF-AGGREGATION, BUTYRYLCHOLINESTERASE, METAL CHELATION, PROPIDIUM DISPLACEMENT, SALICYLIC ACID DERIVATIVES, TACRINE CONJUGATES, 2 METHYL N [4 (1,2,3,4 TETRAHYDROACRIDIN 9 YLAMINO)BUTYL]BENZAMIDE, 2 METHYL N [4 (1,2,3,4 TETRAHYDROACRIDIN 9 YLAMINO)HEXYL]BENZAMIDE, 2 METHYL N [4 (1,2,3,4 TETRAHYDROACRIDIN 9 YLAMINO)OCTYL]BENZAMIDE, 2 [4 (1,2,3,4 TETRAHYDROACRIDIN 9 YLAMINO)BUTYLIMINOMETHYL]PHENOL, 2 [4 (1,2,3,4 TETRAHYDROACRIDIN 9 YLAMINO)HEXYLIMINOMETHYL]PHENOL, 2 [4 (1,2,3,4 TETRAHYDROACRIDIN 9 YLAMINO)OCTYLIMINOMETHYL]PHENOL, 4,5 DIFLUORO 2 HYDROXY N [4 (1,2,3,4 TETRAHYDROACRIDIN 9 YLAMINO)BUTYL]BENZAMIDE, 4,5 DIFLUORO 2 HYDROXY N [4 (1,2,3,4 TETRAHYDROACRIDIN 9 YLAMINO)HEXYL]BENZAMIDE, 4,5 DIFLUORO 2 HYDROXY N [4 (1,2,3,4 TETRAHYDROACRIDIN 9 YLAMINO)OCTYL]BENZAMIDE, 4,5 DIFLUORO 2 METHOXY N [4 (1,2,3,4 TETRAHYDROACRIDIN 9 YLAMINO)BUTYL]BENZAMIDE, 4,5 DIFLUORO 2 METHOXY N [4 (1,2,3,4 TETRAHYDROACRIDIN 9 YLAMINO)HEXYL]BENZAMIDE, 4,5 DIFLUORO 2 METHOXY N [4 (1,2,3,4 TETRAHYDROACRIDIN 9 YLAMINO)OCTYL]BENZAMIDE, AMYLOID BETA PROTEIN[1-42], ANTIOXIDANT, ASCORBIC ACID, CHELATING AGENT, CHOLINESTERASE, CHOLINESTERASE INHIBITOR, COPPER, DONEPEZIL

وصف الملف: application/pdf

العلاقة: Makhaeva, GF, Kovaleva, NV, Rudakova, EV, Boltneva, NP, Grishchenko, MV, Lushchekina, SV, Astakhova, TY, Serebryakova, OG, Timokhina, EN, Zhilina, EF, Shchegolkov, EV, Ulitko, MV, Radchenko, EV, Palyulin, VA, Burgart, YV, Saloutin, VI, Bachurin, SO & Richardson, RJ 2023, 'Conjugates of Tacrine and Salicylic Acid Derivatives as New Promising Multitarget Agents for Alzheimer’s Disease', International Journal of Molecular Sciences, Том. 24, № 3, 2285. https://doi.org/10.3390/ijms24032285Test; Makhaeva, G. F., Kovaleva, N. V., Rudakova, E. V., Boltneva, N. P., Grishchenko, M. V., Lushchekina, S. V., Astakhova, T. Y., Serebryakova, O. G., Timokhina, E. N., Zhilina, E. F., Shchegolkov, E. V., Ulitko, M. V., Radchenko, E. V., Palyulin, V. A., Burgart, Y. V., Saloutin, V. I., Bachurin, S. O., & Richardson, R. J. (2023). Conjugates of Tacrine and Salicylic Acid Derivatives as New Promising Multitarget Agents for Alzheimer’s Disease. International Journal of Molecular Sciences, 24(3), [2285]. https://doi.org/10.3390/ijms24032285Test; Final; All Open Access, Gold, Green; https://www.scopus.com/inward/record.uri?eid=2-s2.0-85148003235&doi=10.3390%2fijms24032285&partnerID=40&md5=fe6438dda642e3160d82a1abfe2c8c8bTest; https://www.mdpi.com/1422-0067/24/3/2285/pdf?version=1675907905Test; http://elar.urfu.ru/handle/10995/130201Test; 85148003235; 000935706300001

الإتاحة: https://doi.org/10.3390/ijms24032285Test
http://elar.urfu.ru/handle/10995/130201Test
https://www.mdpi.com/1422-0067/24/3/2285/pdf?version=1675907905Test

المؤلفون: Chen, X., Li, X., Ji, B., Wang, Y., Ishchuk, O. P., Vorontsov, Egor, 1988, Petranovic, D., Siewers, V., Engqvist, M. K. M.

المصدر: Metabolic Engineering. 72:311-324

مصطلحات موضوعية: Biochemistry and Molecular Biology, Biokemi och molekylärbiologi, Amyloid-β, Cell engineering, Cell stress, Protein misfolding and aggregation, Yeast cell factories, Amino acids, Biochemistry, Biosynthesis, Cytology, Metabolic engineering, Metabolism, Neurodegenerative diseases, Peptides, Recombinant proteins, Transcription, Transcription factors, Yeast, Alzheimers disease, Cellular stress, Disease models, Protein aggregation, Protein misfolding, Recombinant protein productions, Yeast cell, Yeast cell factory, Glycoproteins, amylase, amyloid beta protein, amyloid beta protein[1-42], arginine, membrane lipid, mitochondrial protein, recombinant protein, sulfur amino acid, Article, cell metabolism, gene deletion, gene expression, gene overexpression, genetic transcription, lipogenesis, mitochondrion, nonhuman, oxidative stress, phenotype, protein expression, protein unfolding, proteomics, RNA processing, Saccharomyces cerevisiae, transcriptomics

الوصول الحر: https://gup.ub.gu.se/publication/320779Test

المؤلفون: Bharadwaj, Prashant, Martins, Ralph

المصدر: Research outputs 2014 to 2021

مصطلحات موضوعية: amyloid beta protein[1-42], dimebon, rapamycin, absorption, Alzheimer disease, Article, autophagy (cellular), cell death, cell growth assay, cell survival, cell viability, CFU counting, colony forming unit, controlled study, cytotoxicity, dose response, gene deletion, gene overexpression, high throughput screening, neurotoxicity, nonhuman, Saccharomyces cerevisiae, toxicity assay, Medicine and Health Sciences

وصف الملف: application/pdf

العلاقة: https://ro.ecu.edu.au/ecuworkspost2013/8136Test; https://ro.ecu.edu.au/context/ecuworkspost2013/article/9142/viewcontent/A_rapid_absorbance_based_growth_assay_to_screen_the_toxicity_of_oligomer_ATestβ42_and_protect_against_cell_death_in_yeast.pdf

الإتاحة: https://doi.org/10.4103/1673-5374.280318Test
https://ro.ecu.edu.au/ecuworkspost2013/8136Test
https://ro.ecu.edu.au/context/ecuworkspost2013/article/9142/viewcontent/A_rapid_absorbance_based_growth_assay_to_screen_the_toxicity_of_oligomer_ATestβ42_and_protect_against_cell_death_in_yeast.pdf

المؤلفون: Tomruk, C., Kaplan, Algin, A., Gözde, Aslan, Ç., Saban, Akkurt, S., Mehtap, Çinar, G., Ulukaya, S., Uyanıkgil, Y.

مصطلحات موضوعية: Ozone, Neurodegenerative disease, Parkinson's disease, Rotenone, alpha synuclein, amyloid beta protein, amyloid beta protein[1-42], biological marker, dimethyl sulfoxide, ketamine, tau protein, tyrosine, xylazine, animal cell, animal experiment, animal model, apomorphine test, Article, biochemistry, cell count, controlled study, gene expression, glia cell, immunohistochemistry, male, nerve degeneration, nonhuman, Parkinson disease, protein phosphorylation, rat

العلاقة: Neuroscience Letters; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; https://hdl.handle.net/11454/91565Test; https://doi.org/10.1016/j.neulet.2023.137448Test; 814

الإتاحة: https://doi.org/10.1016/j.neulet.2023.137448Test
https://hdl.handle.net/11454/91565Test

المؤلفون: Shi, Dai, Wong, Jaime K Y, Zhu, Kaichuan, Noakes, Peter G, Rammes, Gerhard

المصدر: International journal of molecular sciences 24(2), 912 (2023). doi:10.3390/ijms24020912

مصطلحات موضوعية: info:eu-repo/classification/ddc/540, Mice, Animals, Isoflurane: pharmacology, Xenon: pharmacology, Xenon: metabolism, Astrocytes: metabolism, Amyloid beta-Peptides: metabolism, Brain: metabolism, Hippocampus: metabolism, Peptide Fragments: metabolism, Alzheimer Disease: metabolism, Anesthetics, Inhalation: pharmacology, Synapses: metabolism, Membrane Proteins: metabolism, Alzheimer’s disease, MEGF10, astrocytes, dendritic spine density, phagocytosis, synapse elimination, amyloid beta-protein (1-42), Isoflurane, Xenon, Amyloid beta-Peptides, Peptide Fragments, Inhalation, Megf10 protein, mouse

جغرافية الموضوع: DE

العلاقة: info:eu-repo/semantics/altIdentifier/issn/1422-0067; info:eu-repo/semantics/altIdentifier/pmid/pmid:36674434; info:eu-repo/semantics/altIdentifier/issn/1661-6596; https://pub.dzne.de/record/194980Test; https://pub.dzne.de/search?p=id:%22DZNE-2023-00167%22Test

الإتاحة: https://doi.org/10.3390/ijms24020912Test
https://pub.dzne.de/record/194980Test
https://pub.dzne.de/search?p=id:%22DZNE-2023-00167%22Test

المؤلفون: Zetterberg, Henrik, Burnham, Samantha C.

المصدر: Research outputs 2014 to 2021

مصطلحات موضوعية: Alzheimer's disease, Amyloid, Biomarkers, Blood, Plasma, Serum, Tau, amyloid beta protein, amyloid beta protein[1-40], amyloid beta protein[1-42], biological marker, microRNA, neurofilament protein, tau protein, Alzheimer disease, blood brain barrier, disease marker, exosome, human, metabolomics, phenotype, priority journal, protein blood level, protein function, protein phosphorylation, Review, Medicine and Health Sciences

وصف الملف: application/pdf

العلاقة: https://ro.ecu.edu.au/ecuworkspost2013/6125Test; https://ro.ecu.edu.au/context/ecuworkspost2013/article/7130/viewcontent/Blood_based_molecular_biomarkers_for_Alzheimer_s_disease.pdfTest

الإتاحة: https://doi.org/10.1186/s13041-019-0448-1Test
https://ro.ecu.edu.au/ecuworkspost2013/6125Test
https://ro.ecu.edu.au/context/ecuworkspost2013/article/7130/viewcontent/Blood_based_molecular_biomarkers_for_Alzheimer_s_disease.pdfTest

المؤلفون: Li, Z.-Y, Chung, Y.H, Shin, E.-J, Dang, D.-K, Jeong, J.H, Ko, S.K, Nah, S.-Y, Baik, T.G, Jhoo, J.H, Ong, W.-Y, Nabeshima, T, Kim, H.-C

المساهمون: ANATOMY

المصدر: Unpaywall 20201031

مصطلحات موضوعية: 1 alkyl 2 acetylglycerophosphocholine esterase, 1 alkyl 2 acetylglycerophosphocholine esterase 1, amyloid beta protein[1-42], amyloid precursor protein, bilobalide, cyclooxygenase 2, Ginkgo biloba extract, ginkgolide A, ginkgolide B, ginkgolide C, isorhamnetin, kaempferol, meloxicam, presenilin 1, quercetin, reactive oxygen metabolite, terpene, thrombocyte activating factor receptor, unclassified drug, yy 1224, amyloid beta protein, amyloid beta-protein (1-42), lactone, peptide fragment, plant extract, trilactone, animal cell, animal experiment, animal model, animal tissue

العلاقة: Li, Z.-Y, Chung, Y.H, Shin, E.-J, Dang, D.-K, Jeong, J.H, Ko, S.K, Nah, S.-Y, Baik, T.G, Jhoo, J.H, Ong, W.-Y, Nabeshima, T, Kim, H.-C (2017). YY-1224, a terpene trilactone-strengthened Ginkgo biloba, attenuates neurodegenerative changes induced by β-amyloid (1-42) or double transgenic overexpression of APP and PS1 via inhibition of cyclooxygenase-2. Journal of Neuroinflammation 14 (1) : 94. ScholarBank@NUS Repository. https://doi.org/10.1186/s12974-017-0866-xTest; https://scholarbank.nus.edu.sg/handle/10635/179510Test

الإتاحة: https://doi.org/10.1186/s12974-017-0866-xTest
https://scholarbank.nus.edu.sg/handle/10635/179510Test

المؤلفون: Pannee, Josef, 1979, Blennow, Kaj, 1958, Zetterberg, Henrik, 1973

المصدر: Cerebrospinal Fluid Biomarkers. Teunissen C.E., Zetterberg H. (eds). :55-69

مصطلحات موضوعية: Neurosciences, Neurovetenskaper, Alzheimer’s disease, Amyloid beta peptides, Cerebrospinal fluid, Liquid chromatography, Mass spectrometry, Solid phase extraction, amyloid beta protein, amyloid beta protein[1-42], carbon 13, nitrogen 15, calibration, controlled study, human, liquid chromatography-mass spectrometry, priority journal, protein analysis, protein cerebrospinal fluid level, radiolabeling

الوصول الحر: https://gup.ub.gu.se/publication/308918Test

المؤلفون: Cacciatore, I., Turkez, H., Di Rienzo, A., Ciulla, M., Mardinoglu, Adil, Di Stefano, A.

المصدر: RSC Medicinal Chemistry. 12(11):1944-1949

مصطلحات موضوعية: acetylcholinesterase, amyloid beta protein[1-42], boron derivative, Alzheimer disease, antioxidant activity, Article, cell differentiation, cell protection, computer model, concentration response, controlled study, drug structure, drug synthesis, enzyme activity, enzyme inhibition, human, human cell, in vitro study, MTT assay, neuroprotection, SH-SY5Y cell line

وصف الملف: print

الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-313207Test