المؤلفون: Parmar, Malin

المصدر: Proceedings of the National Academy of Sciences of the United States of America StemTherapy: National Initiative on Stem Cells for Regenerative Therapy MultiPark: Multidisciplinary research focused on Parkinson´s disease. 119(30)

مصطلحات موضوعية: Animals, Astrocytes/physiology, Coculture Techniques, Dopaminergic Neurons/physiology, Mice, Parkinson Disease/therapy, Protein Aggregates, Rats, alpha-Synuclein/genetics, Medicin och hälsovetenskap, Medicinska och farmaceutiska grundvetenskaper, Neurovetenskaper, Medical and Health Sciences, Basic Medicine, Neurosciences

الوصول الحر: https://lup.lub.lu.se/record/9f66e5c8-3596-4119-8f21-4503295e856fTest
http://dx.doi.org/10.1073/pnas.2208876119Test

المؤلفون: Cappelletti, Chiara, Henriksen, Sandra Pilar, Geut, Hanneke, Rozemuller, Annemieke J M, van de Berg, Wilma D J, Pihlstrøm, Lasse, Toft, Mathias

المصدر: Cappelletti , C , Henriksen , S P , Geut , H , Rozemuller , A J M , van de Berg , W D J , Pihlstrøm , L & Toft , M 2023 , ' Transcriptomic profiling of Parkinson's disease brains reveals disease stage specific gene expression changes ' , Acta Neuropathologica , vol. 146 , no. 2 , pp. 227-244 . https://doi.org/10.1007/s00401-023-02597-7Test

مصطلحات موضوعية: Humans, Parkinson Disease/pathology, Transcriptome, alpha-Synuclein/genetics, Lewy Bodies/pathology, Brain/pathology, Nerve Degeneration/pathology, Protein Serine-Threonine Kinases/metabolism, Intracellular Signaling Peptides and Proteins/metabolism

وصف الملف: application/pdf

العلاقة: https://pure.knaw.nl/portal/en/publications/dbdadf52-c35f-4762-b88e-16d23c80429fTest

الإتاحة: https://doi.org/10.1007/s00401-023-02597-7Test
https://doi.org/20.500.11755/dbdadf52-c35f-4762-b88e-16d23c80429fTest
https://pure.knaw.nl/portal/en/publications/dbdadf52-c35f-4762-b88e-16d23c80429fTest
https://hdl.handle.net/20.500.11755/dbdadf52-c35f-4762-b88e-16d23c80429fTest
https://pure.knaw.nl/ws/files/1019535192/Cappel2023.pdfTest

المؤلفون: Cheng, Fubo, Zheng, Wenxu, Liu, Chang, Barbuti, Peter Antony, Yu-Taeger, Libo, Casadei, Nicolas, Huebener-Schmid, Jeannette, Admard, Jakob, Boldt, Karsten, Junger, Katrin, Ueffing, Marius, Houlden, Henry, Sharma, Manu, Krüger, Rejko, Grundmann-Hauser, Kathrin, Ott, Thomas, Riess, Olaf

المصدر: Science Advances, 8 (47), eabq6324 (2022-11-23)

مصطلحات موضوعية: Humans, alpha-Synuclein/genetics, Apoptosis Regulatory Proteins/metabolism, Brain/metabolism, DNA-Binding Proteins/metabolism, Introns/genetics, Parkinson Disease/metabolism, Polymorphism, Single Nucleotide, Regulatory Sequences, Nucleic Acid, Human health sciences, Neurology, Sciences de la santé humaine, Neurologie

العلاقة: urn:issn:2375-2548; https://orbilu.uni.lu/handle/10993/53880Test; info:hdl:10993/53880; https://orbilu.uni.lu/bitstream/10993/53880/1/sciadv.abq6324%20%281%29.pdfTest; scopus-id:2-s2.0-85142940102; info:pmid:36417521; wos:000906647400005

الإتاحة: https://doi.org/10.1126/sciadv.abq6324Test
https://orbilu.uni.lu/handle/10993/53880Test
https://orbilu.uni.lu/bitstream/10993/53880/1/sciadv.abq6324%20%281%29.pdfTest

المؤلفون: Ghanem, Simona S., Majbour, Nour K., Vaikath, Nishant N., Ardah, Mustafa T., Erskine, Daniel, Jensen, Nanna Møller, Fayyad, Muneera, Sudhakaran, Indulekha P., Vasili, Eftychia, Melachroinou, Katerina, Abdi, Ilham Y., Poggiolini, Ilaria, Santos, Patricia, Dorn, Anton, Carloni, Paolo, Vekrellis, Kostas, Attems, Johannes, McKeith, Ian, Outeiro, Tiago F., Jensen, Poul Henning, El-Agnaf, Omar M.A.

المصدر: Ghanem , S S , Majbour , N K , Vaikath , N N , Ardah , M T , Erskine , D , Jensen , N M , Fayyad , M , Sudhakaran , I P , Vasili , E , Melachroinou , K , Abdi , I Y , Poggiolini , I , Santos , P , Dorn , A , Carloni , P , Vekrellis , K , Attems , J , McKeith , I , Outeiro , T F , Jensen , P H & El-Agnaf , O M A 2022 , ' α-Synuclein phosphorylation ....

مصطلحات موضوعية: Parkinson’s disease, phosphorylation, α-synuclein, Amyloid/metabolism, Protein Aggregates, Protein Aggregation, Pathological/genetics, alpha-Synuclein/genetics, Humans, Serine/metabolism, Lewy Body Disease/genetics, Parkinson Disease/genetics

وصف الملف: application/pdf

العلاقة: https://pure.au.dk/portal/en/publications/53d04145-b1a9-46a8-8f34-7920273d1146Test

الإتاحة: https://doi.org/10.1073/pnas.2109617119Test
https://pure.au.dk/portal/en/publications/53d04145-b1a9-46a8-8f34-7920273d1146Test
https://pure.au.dk/ws/files/353145003/ghanem-et-al-2022-_-synuclein-phosphorylation-at-serine-129-occurs-after-initial-protein-deposition-and-inhibits-seeded.pdfTest
http://www.scopus.com/inward/record.url?scp=85129016122&partnerID=8YFLogxKTest

المؤلفون: Pihlstrøm, Lasse, Shireby, Gemma, Geut, Hanneke, Henriksen, Sandra Pilar, Rozemuller, Annemieke J M, Tunold, Jon-Anders, Hannon, Eilis, Francis, Paul, Thomas, Alan J, Love, Seth, Mill, Jonathan, van de Berg, Wilma D J, Toft, Mathias

المصدر: Pihlstrøm , L , Shireby , G , Geut , H , Henriksen , S P , Rozemuller , A J M , Tunold , J-A , Hannon , E , Francis , P , Thomas , A J , Love , S , Mill , J , van de Berg , W D J & Toft , M 2022 , ' Epigenome-wide association study of human frontal cortex identifies differential methylation in Lewy body pathology ' , Nature Communications , vol. 13 , no. 1 , 4932 . https://doi.org/10.1038/s41467-022-32619-zTest

مصطلحات موضوعية: /dk/atira/pure/core/keywords/dementia_research_group, name=Dementia Research Group, Epigenome, Frontal Lobe/pathology, Humans, Lewy Bodies/metabolism, Lewy Body Disease/genetics, Methylation, Parkinson Disease/genetics, alpha-Synuclein/genetics

وصف الملف: application/pdf

العلاقة: https://research-information.bris.ac.uk/en/publications/28329172-588d-4cd5-aebd-5c51e7305cc4Test

الإتاحة: https://doi.org/10.1038/s41467-022-32619-zTest
https://hdl.handle.net/1983/28329172-588d-4cd5-aebd-5c51e7305cc4Test
https://research-information.bris.ac.uk/en/publications/28329172-588d-4cd5-aebd-5c51e7305cc4Test
https://research-information.bris.ac.uk/ws/files/340232226/s41467_022_32619_z.pdfTest

المؤلفون: Alam, Parvez, Holst, Mikkel R., Lauritsen, Line, Nielsen, Janni, Nielsen, Simone S.E., Jensen, Poul Henning, Brewer, Jonathan R., Otzen, Daniel E., Nielsen, Morten S.

المصدر: Alam , P , Holst , M R , Lauritsen , L , Nielsen , J , Nielsen , S S E , Jensen , P H , Brewer , J R , Otzen , D E & Nielsen , M S 2022 , ' Polarized α-synuclein trafficking and transcytosis across brain endothelial cells via Rab7-decorated carriers ' , Fluids and Barriers of the CNS , vol. 19 , 37 . https://doi.org/10.1186/s12987-022-00334-yTest

مصطلحات موضوعية: Brain endothelial cells and blood brain barrier, Parkinson’s disease, Polarization trap, Rab7, Retromer, Transcytosis, α-synuclein, Endothelium/metabolism, Humans, Parkinson Disease/metabolism, Clathrin/metabolism, rab7 GTP-Binding Proteins, Endothelial Cells/metabolism, alpha-Synuclein/genetics, Brain/metabolism, Vesicular Transport Proteins

وصف الملف: application/pdf

العلاقة: https://portal.findresearcher.sdu.dk/da/publications/3e2553a9-137d-463c-afc1-9d9cc8ebaf5eTest

الإتاحة: https://doi.org/10.1186/s12987-022-00334-yTest
https://portal.findresearcher.sdu.dk/da/publications/3e2553a9-137d-463c-afc1-9d9cc8ebaf5eTest
https://findresearcher.sdu.dk/ws/files/204150815/s12987_022_00334_y.pdfTest

المؤلفون: Fongaro, Benedetta, Cappelletto, Elia, Sosic, Alice, Spolaore, Barbara, Polverino de Laureto, Patrizia

المصدر: Protein Science: A Publication of the Protein Society, 31 (7), e4356 (2022)

مصطلحات موضوعية: DOPAC, DOPET, Parkinson disease, native and HDX-mass spectrometry, protein dynamics, α-synuclein, Catechols, alpha-Synuclein, 3,4-Dihydroxyphenylacetic Acid, 3,4-dihydroxyphenylethanol, Phenylethyl Alcohol, Dopamine, Humans, Phenylethyl Alcohol/analogs & derivatives, Parkinson Disease/genetics, alpha-Synuclein/genetics, Biochemistry, Molecular Biology, Life sciences, Biotechnology, biophysics & molecular biology, Human health sciences, Neurology, Sciences du vivant, Biotechnologie, Biochimie, biophysique & biologie moléculaire, Sciences de la santé humaine, Neurologie

العلاقة: urn:issn:0961-8368; urn:issn:1469-896X; https://orbi.uliege.be/handle/2268/295249Test; info:hdl:2268/295249; https://orbi.uliege.be/bitstream/2268/295249/1/Protein%20Science%20-%202022%20-%20Fongaro%20-%203%204%e2%80%90Dihydroxyphenylethanol%20and%203%204%e2%80%90dihydroxyphenylacetic%20acid%20affect%20the%20aggregation.pdfTest; scopus-id:2-s2.0-85132938935; info:pmid:35762714

الإتاحة: https://doi.org/10.1002/pro.4356Test
https://orbi.uliege.be/handle/2268/295249Test
https://orbi.uliege.be/bitstream/2268/295249/1/Protein%20Science%20-%202022%20-%20Fongaro%20-%203%204%e2%80%90Dihydroxyphenylethanol%20and%203%204%e2%80%90dihydroxyphenylacetic%20acid%20affect%20the%20aggregation.pdfTest

المؤلفون: Lassen, Louise Berkhoudt, Thomsen, Maj Schneider, Basso, Elisa, Füchtbauer, Ernst-Martin, Füchtbauer, Annette, Outeiro, Tiago Fleming, Jensen, Poul Henning, Moos, Torben

المصدر: Lassen , L B , Thomsen , M S , Basso , E , Füchtbauer , E-M , Füchtbauer , A , Outeiro , T F , Jensen , P H & Moos , T 2022 , ' Mutation of Tyrosine Sites in the Human Alpha-Synuclein Gene Induces Neurotoxicity in Transgenic Mice with Soluble Alpha-Synuclein Oligomer Formation ' , Cells , vol. 11 , no. 22 , 3673 . https://doi.org/10.3390/cells11223673Test

مصطلحات موضوعية: Parkinson’s disease, alpha-synuclein, neurodegeneration, tyrosine, serine, transgene, behavior, aggregates, cortico-spinal tract, oligodendrocyte, Phenylalanine, Mutation/genetics, Humans, Mice, Transgenic, Animals, alpha-Synuclein/genetics, Neurotoxicity Syndromes, Serine/genetics

وصف الملف: application/pdf

العلاقة: https://vbn.aau.dk/da/publications/f37ef3f1-1e09-4f6e-a998-d782e0c6c50eTest

الإتاحة: https://doi.org/10.3390/cells11223673Test
https://vbn.aau.dk/da/publications/f37ef3f1-1e09-4f6e-a998-d782e0c6c50eTest
https://vbn.aau.dk/ws/files/502931430/cells_11_03673_v2.pdfTest

المؤلفون: Palazzi, Luana, Fongaro, Benedetta, Leri, Manuela, Acquasaliente, Laura, Stefani, Massimo, Bucciantini, Monica, Polverino de Laureto, Patrizia

المصدر: International Journal of Molecular Sciences, 22 (11), 6008 (2021-06-02)

مصطلحات موضوعية: DOPAC, Parkinson’s disease, autophagy, fibril inhibition, oligomer toxicity, protein oligomerization, α-synuclein aggregation inhibition, Amyloid, SNCA protein, human, alpha-Synuclein, 3,4-Dihydroxyphenylacetic Acid, 3,4-dihydroxyphenylethanol, 3,4-dihydroxyphenylacetaldehyde, Phenylethyl Alcohol, Dopamine, 3,4-Dihydroxyphenylacetic Acid/analogs & derivatives, 3,4-Dihydroxyphenylacetic Acid/pharmacology, Amyloid/drug effects, Amyloid/genetics, Cell Proliferation/drug effects, Dopamine/genetics, Dopamine/metabolism, Dopaminergic Neurons/drug effects, Dopaminergic Neurons/metabolism, Dopaminergic Neurons/pathology, Humans, Oxidative Stress/drug effects, Parkinson Disease/drug therapy, Parkinson Disease/genetics, Parkinson Disease/metabolism, Parkinson Disease/pathology, Phenylethyl Alcohol/analogs & derivatives, Phenylethyl Alcohol/pharmacology, Protein Aggregation, Pathological/drug therapy, Protein Aggregation, Pathological/genetics, Protein Multimerization/genetics, alpha-Synuclein/antagonists & inhibitors, alpha-Synuclein/genetics, Cell Proliferation, Dopaminergic Neurons, Oxidative Stress, Protein Aggregation, Pathological, Protein Multimerization, Catalysis, Molecular Biology, Spectroscopy, Computer Science Applications, Physical and Theoretical Chemistry, Organic Chemistry, Inorganic Chemistry, General Medicine, Life sciences, Biotechnology, Biochemistry, biophysics & molecular biology, Human health sciences, Neurology, Sciences du vivant, Biotechnologie, Biochimie, biophysique & biologie moléculaire, Sciences de la santé humaine, Neurologie

العلاقة: https://www.mdpi.com/1422-0067/22/11/6008/pdfTest; urn:issn:1661-6596; urn:issn:1422-0067

الوصول الحر: https://orbi.uliege.be/handle/2268/295246Test

المؤلفون: Mészáros, Lisa, Riemenschneider, Markus J., Gassner, Heiko, Marxreiter, Franz, von Hörsten, Stephan, Hoffmann, Alana, Schlachetzki, Johannes

المصدر: http://lobid.org/resources/99370678498306441Test#!, 9(1):68.

مصطلحات موضوعية: Cerebellum/pathology [MeSH], Female [MeSH], Aged [MeSH], Cerebellar pathology, Humans [MeSH], Multiple System Atrophy/pathology [MeSH], Middle Aged [MeSH], Multiple system atrophy, Animals [MeSH], Mice, Transgenic [MeSH], Mice [MeSH], Multiple System Atrophy/complications [MeSH], Cerebellar ataxia, Male [MeSH], Research, Gait analysis, alpha-Synuclein/genetics [MeSH], alpha-Synuclein/metabolism [MeSH], Cerebellar Ataxia/etiology [MeSH], Disease Models, Animal [MeSH]

العلاقة: https://repository.publisso.de/resource/frl:6464483Test; https://doi.org/10.1186/s40478-021-01166-xTest; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048356Test/

الإتاحة: https://doi.org/10.1186/s40478-021-01166-xTest
https://repository.publisso.de/resource/frl:6464483Test
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8048356Test/