المؤلفون: Oosterhof, Marloes, Coussement, Louis, van Pijkeren, Alienke, Kwiatkowski, Marcel, Zwinderman, Martijn R. H., Dekker, Frank J., De Meyer, Tim, Reitsema, Vera A., Bischoff, Rainer, Guryev, Victor, Bouma, Hjalmar R., Henning, Rob H., Rots, Marianne G.

المصدر: EPIGENETICS COMMUNICATIONS ; ISSN: 2730-7034

مصطلحات موضوعية: Biology and Life Sciences, HDAC, HAT, RNA sequencing, Epigenetics, Histone acetylation, WGBS

وصف الملف: application/pdf

العلاقة: https://biblio.ugent.be/publication/01J03AQ4W54JP6QJ5DDVWEND11Test; http://hdl.handle.net/1854/LU-01J03AQ4W54JP6QJ5DDVWEND11Test; http://doi.org/10.1186/s43682-023-00024-2Test; https://biblio.ugent.be/publication/01J03AQ4W54JP6QJ5DDVWEND11/file/01J03ATC83B7ZDB67V7CP1S7P7Test

الإتاحة: https://doi.org/10.1186/s43682-023-00024-2Test
https://biblio.ugent.be/publication/01J03AQ4W54JP6QJ5DDVWEND11Test
http://hdl.handle.net/1854/LU-01J03AQ4W54JP6QJ5DDVWEND11Test
https://biblio.ugent.be/publication/01J03AQ4W54JP6QJ5DDVWEND11/file/01J03ATC83B7ZDB67V7CP1S7P7Test

المؤلفون: van der Wouden, Petra E., Zwinderman, Martijn R. H., Chen, Deng, Borghesan, Michela, Dekker, Frank J.

المصدر: van der Wouden , P E , Zwinderman , M R H , Chen , D , Borghesan , M & Dekker , F J 2023 , ' Protocol of the Double-Click Seq Method to Evaluate the Deposition Bias of Chromatin Proteins ' , Current Protocols , vol. 3 , no. 6 , e805 . https://doi.org/10.1002/cpz1.805Test

مصطلحات موضوعية: chromatin proteins, DNA replication, double-click seq, Ethynyl-2′-deoxyuridine (EdU), histone deposition, l-Azidohomoalanine (AHA)

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/51f3112f-d30a-458d-9d3d-86706a36761aTest

الإتاحة: https://doi.org/10.1002/cpz1.805Test
https://hdl.handle.net/11370/51f3112f-d30a-458d-9d3d-86706a36761aTest
https://research.rug.nl/en/publications/51f3112f-d30a-458d-9d3d-86706a36761aTest
https://pure.rug.nl/ws/files/747301613/Current_Protocols_-_2023_-_Wouden.pdfTest
http://www.scopus.com/inward/record.url?scp=85163372683&partnerID=8YFLogxKTest

المؤلفون: Zwinderman, Martijn R. H.

المصدر: Zwinderman , M R H 2021 , ' Deacetylase inhibitors & Histone inheritance ' , Doctor of Philosophy , University of Groningen , [Groningen] . https://doi.org/10.33612/diss.167867692Test

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/0d30d677-b630-4cf2-8ed4-a4684d6c8e8fTest

الإتاحة: https://doi.org/10.33612/diss.167867692Test
https://hdl.handle.net/11370/0d30d677-b630-4cf2-8ed4-a4684d6c8e8fTest
https://research.rug.nl/en/publications/0d30d677-b630-4cf2-8ed4-a4684d6c8e8fTest
https://pure.rug.nl/ws/files/167867694/Title_and_contents.pdfTest
https://pure.rug.nl/ws/files/167867696/Chapter_1.pdfTest
https://pure.rug.nl/ws/files/167867698/Chapter_2.pdfTest
https://pure.rug.nl/ws/files/167867700/Chapter_3.pdfTest
https://pure.rug.nl/ws/files/167867702/Chapter_4.pdfTest
https://pure.rug.nl/ws/files/167867704/Chapter_5.pdfTest
https://pure.rug.nl/ws/files/167867706/Chapter_6.pdfTest

المؤلفون: Zwinderman, Martijn R H, Lobo, Thamar Jessurun, van der Wouden, Petra E, Spierings, Diana C J, van Vugt, Marcel A T M, Lansdorp, Peter M, Guryev, Victor, Dekker, Frank J

المصدر: Zwinderman , M R H , Lobo , T J , van der Wouden , P E , Spierings , D C J , van Vugt , M A T M , Lansdorp , P M , Guryev , V & Dekker , F J 2021 , ' Deposition Bias of Chromatin Proteins Inverts under DNA Replication Stress Conditions ' , ACS chemical biology , vol. 16 , no. 11 , pp. 2193-2201 . https://doi.org/10.1021/acschembio.1c00321Test

مصطلحات موضوعية: ATR, HELICASE, BINDING, DAMAGE

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/6084b91d-744f-4776-8b32-d22d987099b5Test

الإتاحة: https://doi.org/10.1021/acschembio.1c00321Test
https://hdl.handle.net/11370/6084b91d-744f-4776-8b32-d22d987099b5Test
https://research.rug.nl/en/publications/6084b91d-744f-4776-8b32-d22d987099b5Test
https://pure.rug.nl/ws/files/189881738/acschembio.1c00321.pdfTest

المؤلفون: Zwinderman, Martijn, Cao, Fangyuan, Dekker, Frank

المساهمون: Mai, Antonello

المصدر: Zwinderman , M , Cao , F & Dekker , F 2019 , Acetylation and Methylation in Asthma, COPD, and Lung Cancer . in A Mai (ed.) , Chemical Epigenetics : Topics in Medicinal Chemistry . Topics in Medicinal Chemistry , vol. 33 , Springer Nature , Cham , pp. 429-455 . https://doi.org/10.1007/7355_2019_81Test

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/0c64849c-9f99-4ca8-9d26-fda0df456eb3Test; urn:ISBN:978-3-030-42981-2

الإتاحة: https://doi.org/10.1007/7355_2019_81Test
https://hdl.handle.net/11370/0c64849c-9f99-4ca8-9d26-fda0df456eb3Test
https://research.rug.nl/en/publications/0c64849c-9f99-4ca8-9d26-fda0df456eb3Test
https://pure.rug.nl/ws/files/569420399/7355_2019_81.pdfTest

المؤلفون: Cao, Fangyuan, de Weerd, Sander, Chen, Deng, Zwinderman, Martijn R H, van der Wouden, Petra E, Dekker, Frank J

المصدر: Cao , F , de Weerd , S , Chen , D , Zwinderman , M R H , van der Wouden , P E & Dekker , F J 2020 , ' Induced protein degradation of histone deacetylases 3 (HDAC3) by proteolysis targeting chimera (PROTAC) ' , European Journal of Medicinal Chemistry , vol. 208 , 112800 . https://doi.org/10.1016/j.ejmech.2020.112800Test

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/7dc0a755-94f3-4649-80a9-a73ba2628721Test

الإتاحة: https://doi.org/10.1016/j.ejmech.2020.112800Test
https://hdl.handle.net/11370/7dc0a755-94f3-4649-80a9-a73ba2628721Test
https://research.rug.nl/en/publications/7dc0a755-94f3-4649-80a9-a73ba2628721Test
https://pure.rug.nl/ws/files/134697662/1_s2.0_S0223523420307728_main.pdfTest

المؤلفون: Liu, Bin, Chen, Siwei, Chen, Deng, Cao, Fangyuan, Zwinderman, Martijn, Kiemel, Dominik, Aïssi, Manon, Dekker, Frank J., Haisma, Hidde J., La Rose, Anouk

المصدر: Liu , B , Chen , S , Chen , D , Cao , F , Zwinderman , M , Kiemel , D , Aïssi , M , Dekker , F J , Haisma , H J & La Rose , A 2020 , ' Inhibition of histone deacetylase 1 (HDAC1) and HDAC2 enhances CRISPR/Cas9 genome editing ' , Nucleic Acids Research , vol. 48 , no. 2 , pp. 517-532 . https://doi.org/10.1093/nar/gkz1136Test

مصطلحات موضوعية: CHROMATIN-STRUCTURE, DNA, SPECIFICITY, BACTERIA, SYSTEM, RECOMBINATION, TRANSCRIPTION, ACETYLATION, SITES, CAS9

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/986eb1c8-3266-4aa9-8ddd-153a096e56c9Test

الإتاحة: https://doi.org/10.1093/nar/gkz1136Test
https://hdl.handle.net/11370/986eb1c8-3266-4aa9-8ddd-153a096e56c9Test
https://research.rug.nl/en/publications/986eb1c8-3266-4aa9-8ddd-153a096e56c9Test
https://pure.rug.nl/ws/files/117808457/gkz1136.pdfTest

المؤلفون: Zwinderman, Martijn R. H., de Weerd, Sander, Dekker, Frank J.

المصدر: Zwinderman , M R H , de Weerd , S & Dekker , F J 2019 , ' Targeting HDAC Complexes in Asthma and COPD ' , Epigenomes , vol. 3 , no. 3 , 19 . https://doi.org/10.3390/epigenomes3030019Test

مصطلحات موضوعية: asthma, COPD, inflammation, NF-kappa B, HDAC, acetylation, post translational modification (PTM), inhibitor, drug design, co-repressor complex, review, HISTONE DEACETYLASE INHIBITORS, NF-KAPPA-B, GLUCOCORTICOID-RECEPTOR-BETA, GENE-EXPRESSION PROGRAM, TRANSCRIPTIONAL REPRESSION, CORTICOSTEROID RESISTANCE, COREPRESSOR COMPLEX, STRUCTURAL BASIS, PROSTATE-CANCER, BREAST-CANCER

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/36793d47-b49f-426f-8696-9ddec551cc4dTest

الإتاحة: https://doi.org/10.3390/epigenomes3030019Test
https://hdl.handle.net/11370/36793d47-b49f-426f-8696-9ddec551cc4dTest
https://research.rug.nl/en/publications/36793d47-b49f-426f-8696-9ddec551cc4dTest
https://pure.rug.nl/ws/files/99950758/epigenomes_03_00019.pdfTest

المؤلفون: Cao, Fangyuan, Zwinderman, Martijn, van Merkerk, Ronald, Ettema, Petra, Quax, Wim, Dekker, Frank J.

المصدر: Cao , F , Zwinderman , M , van Merkerk , R , Ettema , P , Quax , W & Dekker , F J 2019 , ' Inhibitory selectivity among class I HDACs has a major impact on inflammatory gene expression in macrophages ' , European Journal of Medicinal Chemistry , vol. 177 , pp. 457-466 . https://doi.org/10.1016/j.ejmech.2019.05.038Test

مصطلحات موضوعية: HISTONE DEACETYLASE HDAC

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/d82069cb-8b0e-4948-b113-bddacc462338Test

الإتاحة: https://doi.org/10.1016/j.ejmech.2019.05.038Test
https://hdl.handle.net/11370/d82069cb-8b0e-4948-b113-bddacc462338Test
https://research.rug.nl/en/publications/d82069cb-8b0e-4948-b113-bddacc462338Test
https://pure.rug.nl/ws/files/85444223/1_s2.0_S0223523419304489_main.pdfTest

المؤلفون: Wójcik, Magdalena, Eleftheriadis, Nikolaos, Zwinderman, Martijn R H, Dömling, Alexander S S, Dekker, Frank J, Boersma, Ykelien L

المصدر: Wójcik , M , Eleftheriadis , N , Zwinderman , M R H , Dömling , A S S , Dekker , F J & Boersma , Y L 2019 , ' Identification of potential antivirulence agents by substitution-oriented screening for inhibitors of Streptococcus pyogenes sortase A ' , European Journal of Medicinal Chemistry , vol. 161 , pp. 93-100 . https://doi.org/10.1016/j.ejmech.2018.10.027Test

مصطلحات موضوعية: PROTEINS, TARGET, PATHOGENESIS, 15-LIPOXYGENASE-1

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/e90b7e4a-bdd1-466a-a4eb-56312fb04f7bTest

الإتاحة: https://doi.org/10.1016/j.ejmech.2018.10.027Test
https://hdl.handle.net/11370/e90b7e4a-bdd1-466a-a4eb-56312fb04f7bTest
https://research.rug.nl/en/publications/e90b7e4a-bdd1-466a-a4eb-56312fb04f7bTest
https://pure.rug.nl/ws/files/72013673/1_s2.0_S022352341830895X_main.pdfTest