المؤلفون: Mistretta, Maxime, Cimino, Mena, Campagne, Pascal, Volant, Stevenn, Kornobis, Etienne, Hebert, Olivier, Rochais, Christophe, Dallemagne, Patrick, Lecoutey, Cédric, Tisnerat, Camille, Lepailleur, Alban, Ayotte, Yann, Laplante, Steven, Gangneux, Nicolas, Záhorszká, Monika, Korduláková, Jana, Vichier-Guerre, Sophie, Bonhomme, Frédéric, Pokorny, Laura, Albert, Marvin, Tinevez, Jean-Yves, Manina, Giulia

المساهمون: Individualité microbienne et infection - Microbial Individuality and Infection, Institut Pasteur Paris (IP)-Université Paris Cité (UPCité), Hub Bioinformatique et Biostatistique - Bioinformatics and Biostatistics HUB, Université de Caen Normandie (UNICAEN), Normandie Université (NU), Centre d'Etudes et de Recherche sur le Médicament de Normandie (CERMN), Normandie Université (NU)-Normandie Université (NU), Institut Armand Frappier (INRS-IAF), Institut National de la Recherche Scientifique Québec (INRS)-Réseau International des Instituts Pasteur (RIIP), Comenius University in Bratislava, Chimie biologique épigénétique - Epigenetic Chemical Biology (EpiCBio), Institut Pasteur Paris (IP)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Hub d'analyse d'images - Image Analysis Hub (Platform) (IAH), This work was supported by the following grants: French Medical Research Foundation grant ING20160435202 to G.M., French National Research Agency grant ANR-17-CE11-0007-01 PersisTB to G.M., French National Research Agency grant ANR-10-LABX-62-IBEID to G.M., and Institut Pasteur core funding to G.M. The work was further supported by the French National Research Agency grant ANR-21-CE15-0045 TREATABLE to G.M. and C.R., by the Slovak Research and Development Agency grant n. APVV-19-0189 and the OPII, ACCORD, ITMS2014 + : 313021×329, co-financed by ERDF to J.K, and by the Programme d’Investissement d’Avenir MUSTART ANR-20-PAMR-0005 to G.M., We thank Guillaume Duménil (Pathogenesis of vascular infections, Institut Pasteur, Paris, France), Katarína Mikušová (Comenius University in Bratislava, Slovakia), and Pietro Slavich (LPTHE, Paris, France) for critical readings of the manuscript. We thank Samy Gobaa for providing us access to the Biomaterials & Microfluidics core facility of the Institut Pasteur. We thank the FabLab of the Institut Pasteur for manufacturing holders and reservoirs associated with the microfluidic device. We thank the Biomics Platform, C2RT, Institut Pasteur, Paris, France, supported by France Génomique (ANR-10-INBS-09-09) and IBISA for assistance in RNA-Seq and WGS. The mutant strains in Supplementary Data 6 were obtained from the Collection of the Institut Pasteur (CIP), Biological Resource Center of Institut Pasteur (CRBIP), Paris, France., ANR-17-CE11-0007,PersisTB,Lutter contre l'épidémie mondiale de tuberculose: Exploiter la variation cellule à cellule afin d'entraver la persistance adaptative(2017), ANR-10-LABX-0062,IBEID,Integrative Biology of Emerging Infectious Diseases(2010), ANR-21-CE15-0045,TREATABLE,Cibler la variation phénotypique pour améliorer le traitement de la tuberculose(2021), ANR-20-PAMR-0005,Mustart,Multiparametric Strategies against Antibiotic Resistance in Tuberculosis(2020)

المصدر: ISSN: 2041-1723.

مصطلحات موضوعية: [SDV]Life Sciences [q-bio], [CHIM]Chemical Sciences

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/38755132; hal-04578611; https://hal.science/hal-04578611Test; https://hal.science/hal-04578611/documentTest; https://hal.science/hal-04578611/file/s41467-024-48269-2.pdfTest; PUBMED: 38755132

الإتاحة: https://doi.org/10.1038/s41467-024-48269-2Test
https://hal.science/hal-04578611Test
https://hal.science/hal-04578611/documentTest
https://hal.science/hal-04578611/file/s41467-024-48269-2.pdfTest

المؤلفون: Faïon, Léo, Djaout, Kamel, Pintiala, Catalin, Piveteau, Catherine, Leroux, Florence, Biela, Alexandre, Slupek, Stéphanie, Antoine, Rudy, Záhorszká, Monika, Cantrelle, Francois-Xavier, Hanoulle, Xavier, Korduláková, Jana, Deprez, Benoit, Willand, Nicolas, Baulard, Alain, Flipo, Marion

المساهمون: Médicaments et molécules pour agir sur les Systèmes Vivants - U 1177 (M2SV), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille, Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 (CIIL), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille)-Centre National de la Recherche Scientifique (CNRS), Plateformes Lilloises en Biologie et Santé - UAR 2014 - US 41 (PLBS), Comenius University in Bratislava, Biologie Structurale Intégrative (ERL 9002 - BSI ), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre National de la Recherche Scientifique (CNRS), Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 (RID-AGE), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire CHU Lille (CHRU Lille), ANR-20-PAMR-0005,Mustart,Multiparametric Strategies against Antibiotic Resistance in Tuberculosis(2020)

المصدر: ISSN: 1424-8247 ; Pharmaceuticals ; https://hal.science/hal-04007450Test ; Pharmaceuticals, 2023, 16 (3), pp.335. ⟨10.3390/ph16030335⟩.

مصطلحات موضوعية: anthranilic acid, FabG1, tuberculosis, mycolic acids, MabA inhibitors, [CHIM.THER]Chemical Sciences/Medicinal Chemistry, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, [SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/Bacteriology, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology

العلاقة: hal-04007450; https://hal.science/hal-04007450Test; https://hal.science/hal-04007450/documentTest; https://hal.science/hal-04007450/file/pharmaceuticals-16-00335-v2.pdfTest

الإتاحة: https://doi.org/10.3390/ph16030335Test
https://hal.science/hal-04007450Test
https://hal.science/hal-04007450/documentTest
https://hal.science/hal-04007450/file/pharmaceuticals-16-00335-v2.pdfTest

المؤلفون: Salina, Elena G., Postiglione, Umberto, Chiarelli, Laurent R., Recchia, Deborah, Záhorszká, Monika, Lepioshkin, Alexander, Monakhova, Natalia, Pál, Adrian, Porta, Alessio, Zanoni, Giuseppe, Korduláková, Jana, Kazakova, Elena, Sassera, Davide, Pasca, Maria Rosalia, Makarov, Vadim, Degiacomi, Giulia

المساهمون: Bradford, Patricia A., Slovak Research and Development Agency, Ministry of Science and Higher Education of the Russian Federation, EC | European Regional Development Fund, Ministero dell'Università e della Ricerca, Russian Science Foundation, Università degli Studi di Pavia

المصدر: mSphere ; volume 7, issue 6 ; ISSN 2379-5042

الإتاحة: https://doi.org/10.1128/msphere.00369-22Test

المؤلفون: Farjallah, Asma, Chiarelli, Laurent, Forbak, Martin, Degiacomi, Giulia, Danel, Mathieu, Goncalves, Fernanda, Carayon, Chantal, Seguin, Cendrine, Fumagalli, Marco, Záhorszká, Monika, Vega, Elodie, Abid, Souhir, Grzegorzewicz, Anna, Jackson, Mary, Peixoto, Antonio, Korduláková, Jana, Pasca, Maria Rosalia, Lherbet, Christian, Chassaing, Stefan

المساهمون: Institut des Technologies Avancées en sciences du Vivant (ITAV), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS), Université de Sfax - University of Sfax, Università degli Studi di Pavia = University of Pavia (UNIPV), Comenius University in Bratislava, Synthèse et Physico-Chimie de Molécules d'Intérêt Biologique (SPCMIB), Institut de Chimie de Toulouse (ICT), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS), Conception et application de molécules bioactives (CAMB), Université de Strasbourg (UNISTRA)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS), Institut de pharmacologie et de biologie structurale (IPBS), Jouf University, Colorado State University Fort Collins (CSU), Institut de Chimie de Strasbourg

المصدر: EISSN: 2373-8227 ; ACS Infectious Diseases ; https://hal.science/hal-03209886Test ; ACS Infectious Diseases, 2021, 7 (3), pp.552-565. ⟨10.1021/acsinfecdis.0c00325⟩

مصطلحات موضوعية: HadA, Mycobacterium tuberculosis, coumarin, fluorescence, thiacetazone, [CHIM]Chemical Sciences

العلاقة: hal-03209886; https://hal.science/hal-03209886Test; https://hal.science/hal-03209886/documentTest; https://hal.science/hal-03209886/file/CoumTAC-ACSInfDisREVISED_APedit.pdfTest

الإتاحة: https://doi.org/10.1021/acsinfecdis.0c00325Test
https://hal.science/hal-03209886Test
https://hal.science/hal-03209886/documentTest
https://hal.science/hal-03209886/file/CoumTAC-ACSInfDisREVISED_APedit.pdfTest

المؤلفون: Sabbah, Mohamad, Mendes, Vitor, Vistal, Robert G., Dias, David M. G., Záhorszká, Monika, Mikušová, Katarína, Korduláková, Jana, Coyne, Anthony G., Blundell, Tom L., Abell, Chris

المساهمون: Ministerstvo ?kolstva, vedy, v?skumu a ?portu Slovenskej republiky, European Regional Development Fund, Bill and Melinda Gates Foundation, National Institutes of Health, Funda??o para a Ci?ncia e a Tecnologia, Seventh Framework Programme, Agent?ra na Podporu V?skumu a V?voja

المصدر: Journal of Medicinal Chemistry ; volume 63, issue 9, page 4749-4761 ; ISSN 0022-2623 1520-4804

الإتاحة: https://doi.org/10.1021/acs.jmedchem.0c00007Test

المؤلفون: Sabbah, Mohamad, Mendes, Vitor, Vistal, Robert G., Dias, David M. G., Záhorszká, Monika, Mikušová, Katarína, Korduláková, Jana, Coyne, Anthony G., Blundell, Tom L., Abell, Chris

المصدر: Journal of Medicinal Chemistry ; volume 63, issue 15, page 8650-8650 ; ISSN 0022-2623 1520-4804

مصطلحات موضوعية: Drug Discovery, Molecular Medicine

الإتاحة: https://doi.org/10.1021/acs.jmedchem.0c01187Test

المؤلفون: Dutta, Amit K., Choudhary, Eira, Wang, Xuan, Záhorszka, Monika, Forbak, Martin, Lohner, Philipp Simon, Jessen, Henning, Agarwal, Nisheeth, Korduláková, Jana, Jessen-Trefzer, Claudia

المصدر: ACS central science. - 5 (2019) , 644-650, ISSN: 2374-7951

وصف الملف: pdf

العلاقة: https://freidok.uni-freiburg.de/data/152373Test

الإتاحة: https://doi.org/10.1021/acscentsci.8b00962Test
https://freidok.uni-freiburg.de/data/152373Test
https://nbn-resolving.org/urn:nbn:de:bsz:25-freidok-1523731Test
https://freidok.uni-freiburg.de/dnb/download/152373Test

المؤلفون: Madacki, Jan, Laval, Françoise, Grzegorzewicz, Anna, Lemassu, Anne, Záhorszká, Monika, Arand, Michael, Mcneil, Michael, Daffé, Mamadou, Jackson, Mary, Lanéelle, Marie-Antoinette, Korduláková, Jana

المساهمون: Comenius University in Bratislava, Institut de pharmacologie et de biologie structurale (IPBS), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Centre National de la Recherche Scientifique (CNRS), Colorado State University Fort Collins (CSU), Universität Zürich Zürich = University of Zurich (UZH)

المصدر: ISSN: 0021-9258.

مصطلحات موضوعية: mycobacteria, cell wall, fatty acid metabolism, lipid, mass spectrometry (MS), bacterial cell envelope, epoxide hydrolase, epoxymycolic acid, mycolic acids, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM]

العلاقة: hal-02352263; https://hal.science/hal-02352263Test; https://hal.science/hal-02352263/documentTest; https://hal.science/hal-02352263/file/5172.full.pdfTest

الإتاحة: https://doi.org/10.1074/jbc.RA117.000246Test
https://hal.science/hal-02352263Test
https://hal.science/hal-02352263/documentTest
https://hal.science/hal-02352263/file/5172.full.pdfTest

المؤلفون: CHIARELLI, Laurent, FORBAK, Martin, DEGIACOMI, Giulia, DANEL, Mathieu, GONCALVES, Fernanda, CARAYON, Chantal, SEGUIN, Cendrine, FUMAGALLI, Marco, ZÁHORSZKÁ, Monika, VEGA, Elodie, ABID, Souhir, GRZEGORZEWICZ, Anna, JACKSON, Mary, PEIXOTO, Antonio, KORDULÁKOVÁ, Jana, PASCA, Maria Rosalia, LHERBET, Christian, CHASSAING, Stefan, FARJALLAH, Asma

مصطلحات موضوعية: Chimie

العلاقة: https://oskar-bordeaux.fr/handle/20.500.12278/38730Test

الإتاحة: https://doi.org/20.500.12278/38730Test
https://doi.org/10.1021/acsinfecdis.0c00325Test
https://oskar-bordeaux.fr/handle/20.500.12278/38730Test
https://hdl.handle.net/20.500.12278/38730Test