دورية أكاديمية

Population data and forensic genetic evaluation with the Yfiler™ Plus PCR amplification kit in the Lithuanian population

التفاصيل البيبلوغرافية
العنوان: Population data and forensic genetic evaluation with the Yfiler™ Plus PCR amplification kit in the Lithuanian population
المؤلفون: Jankauskienė, Jūratė, Kukienė, Jolanta, Ivanova, Vilma, Aleknavičiūtė, Goda
المصدر: Forensic science international : genetics supplement series, Shannon : Elsevier Ireland LTD, 2017, Volume 6, p. 606-607 ; ISSN 1875-1768 ; eISSN 1875-175X
سنة النشر: 2017
المجموعة: LSRC VL (Lithuanian Social Research Centre Virtual Library) / LSTC VB (Lietuvos socialinių tyrimų centras virtualią biblioteką)
مصطلحات موضوعية: Genetic, forensic genetic, YfilerPlus, population data
الوصف: The analysis of Y-STR markers is used to identify victims from natural disasters, rapes or murder, sexual assault cases; moreover it provides information about genetic diversity and can determine genetic differences in population. Yfiler™ Plus PCR Amplification kit (Thermo Fisher Scientific, Waltham, MA, USA) has 6-dye technology and can amplify 27 Y-STR loci including 7 rapidly mutating markers (RM Y-STRs) and 11 mini-Y-STRs. This study reports on the genotyping of 254 individuals from Lithuania were analysed using Yfiler™ Plus PCR Amplification kit (Thermo Fisher Scientific, Waltham, MA, USA). Forensic and population genetic parameters were calculated using relative computer equipment, statistical approaches and computational tools. Population comparison with other European populations from YHRD was performed. Our results revealed that 27 Y-STR loci provides high haplotype diversity, high discrimination power and is an effective tool in forensic genetics. After comparing data of allelic percentage distribution in each examined Y chromosome locus and genetic diversity in these microsatellite areas between Lithuania’s and other world’s populations, Lithuanian population is not very polymorphic or unique and isolated from other populations. When comparing genetic distances, an observation was made, that Lithuanian population with its Y chromosome genetically is the closest to Russian populations. In conclusion, the Yfiler™ Plus PCR Amplification kit (Thermo Fisher Scientific, Waltham, MA, USA) is very useful in daily casework in forensic laboratories.
نوع الوثيقة: article in journal/newspaper
اللغة: English
العلاقة: http://vu.lvb.lt/VU:ELABAPDB26008077&prefLang=en_USTest
الإتاحة: https://doi.org/10.1016/j.fsigss.2017.10.009Test
http://vu.lvb.lt/VU:ELABAPDB26008077&prefLang=en_USTest
رقم الانضمام: edsbas.4F6D636E
قاعدة البيانات: BASE