دورية أكاديمية
A Meta-Analysis of the Efficacy of L-Carnitine/L-Acetyl-Carnitine or N-Acetyl-Cysteine in Men With Idiopathic Asthenozoospermia
| العنوان: | A Meta-Analysis of the Efficacy of L-Carnitine/L-Acetyl-Carnitine or N-Acetyl-Cysteine in Men With Idiopathic Asthenozoospermia |
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| المؤلفون: | Guangzhu Wei MD, Zhongbao Zhou MD, Yuanshan Cui MD, Yongjin Huang MD, Zijin Wan MM, Xuanyan Che MM, Yumeng Chai MM, Yong Zhang MD |
| المصدر: | American Journal of Men's Health, Vol 15 (2021) |
| بيانات النشر: | SAGE Publishing, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | Medicine |
| الوصف: | The meta-analysis was performed to access efficacy of L-carnitine/L-acetyl-carnitine (LC/LAC) and N-acetyl-cysteine (NAC) in men with idiopathic asthenozoospermia. We researched PubMed, EMBASE, and Cochrane Library databases and references to related articles. Finally, seven articles including 621 patients were analyzed. The results indicated that LC/LAC and NAC had a considerable improvement in sperm motility ( p = .03 and p < .0001, respectively) and normal morphology ( p = .006, p = .0002, respectively) compared with the placebo group. Besides, NAC had a significantly greater increase in sperm concentration ( p < .00001) and ejaculate volume ( p = .002) compared with the placebo group, and there was no significant difference in LC/LAC. For the analysis of serum hormones, NAC had no obvious differences in improving the serum testosterone, luteinizing hormone, follicle-stimulating hormone, and prolactin compared with non-treatment group. Conclusively, LC/LAC and NAC showed a greater improvement in sperm motility and normal morphology. Moreover, NAC has a positive effect on sperm concentration and ejaculate volume, whereas no obvious effect was observed in serum hormones. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1557-9891 15579883 |
| العلاقة: | https://doaj.org/toc/1557-9891Test |
| DOI: | 10.1177/15579883211011371 |
| الوصول الحر: | https://doaj.org/article/f3a57bb5cabc4565b98206b66a8ee884Test |
| رقم الانضمام: | edsdoj.f3a57bb5cabc4565b98206b66a8ee884 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 15579891 15579883 |
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| DOI: | 10.1177/15579883211011371 |