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1دورية أكاديمية
المؤلفون: Ran Pan, Xiaolun Wang, Min Shu, Jaydeep Das, Manik Kalra, Zhidong Wang, Lishao Guo
المصدر: Chinese Medical Journal, Vol 135, Iss 1, Pp 11-19 (2022)
مصطلحات موضوعية: Medicine
وصف الملف: electronic resource
العلاقة: http://journals.lww.com/10.1097/CM9.0000000000001817Test; https://doaj.org/toc/0366-6999Test; https://doaj.org/toc/2542-5641Test
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2دورية أكاديمية
المؤلفون: Mitsuharu Matsumoto, Hiroaki Yashiro, Hitomi Ogino, Kazunobu Aoyama, Tadahiro Nambu, Sayuri Nakamura, Mayumi Nishida, Xiaolun Wang, Derek M Erion, Manami Kaneko
المصدر: PLoS ONE, Vol 15, Iss 1, p e0228212 (2020)
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/1932-6203Test
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3دورية أكاديمية
المؤلفون: Derek Erion, Hiroaki Yashiro, Hitomi Ogino, Kazunobu Aoyama, Manami Kaneko, Mayumi Nishida, Mitsuharu Matsumoto, Tadahiro Nambu, Xiaolun Wang, エリオン デレック, ワング シァオラン, 南部 忠洋, 松本 光晴, 矢代 博昭, 荻野 ひとみ, 西田 真由美, 金子 まなみ, 青山 和誠
المصدر: Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2019, :3-094
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4دورية أكاديمية
المؤلفون: John M. Ketcham, Stephen J. Harwood, Ruth Aranda, Athenea N. Aloiau, Briana M. Bobek, David M. Briere, Aaron C. Burns, Kersti Caddell Haatveit, Andrew Calinisan, Jeffery Clarine, Adam Elliott, Lars D. Engstrom, Robin J. Gunn, Anthony Ivetac, Benjamin Jones, Jon Kuehler, J. David Lawson, Natalie Nguyen, Cody Parker, Kelly E. Pearson, Lisa Rahbaek, Barbara Saechao, Xiaolun Wang, Anna Waters, Laura Waters, Ashlee H. Watkins, Peter Olson, Christopher R. Smith, James G. Christensen, Matthew A. Marx
مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, three pan mutant, ray cocrystal structures, provided tumor regressions, normal cellular processes, kinase domain wherein, hcc1954 tumor model, clear pharmacodynamic response, several pi3kα inhibitors, selective pi3kα inhibitors, wt sup, including glucose homeostasis, selectively targeting pi3kα, 17 b, h1047r sup, pik3ca <, selectively inhibit, one pi3kα, inhibit pi3kα, solid tumors
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5دورية أكاديمية
المؤلفون: Christopher R. Smith, Dan Chen, James G. Christensen, René Coulombe, James Féthière, Robin J. Gunn, Johan Hollander, Benjamin Jones, John M. Ketcham, Shilpi Khare, Jon Kuehler, J. David Lawson, Matthew A. Marx, Peter Olson, Kelly E. Pearson, Cynthia Ren, Denise Tsagris, Thirumalaiselvi Ulaganathan, Inge Van’t Veer, Xiaolun Wang, Anthony Ivetac
مصطلحات موضوعية: Biochemistry, Pharmacology, Biotechnology, Cancer, Chemical Sciences not elsewhere classified, stimulated ras activation, ray cocrystal structures, binding modes determined, based screening strategy, sos1 inhibitor bi, kras ppi inhibitors, kras inhibitors, selective sos1, therapeutic interest, mediate rtk, mapk rebound, identify x, clinical investigation
الإتاحة: https://doi.org/10.1021/acs.jmedchem.3c02140.s001Test
https://figshare.com/articles/journal_contribution/Discovery_of_Five_SOS2_Fragment_Hits_with_Binding_Modes_Determined_by_SOS2_X_Ray_Cocrystallography/24917166Test -
6دورية أكاديمية
المؤلفون: Agustin Casimiro-Garcia (1776715), Christophe Allais (1470982), Agnes Brennan (2414851), Chulho Choi (1490590), Gabriela Dower (11888140), Kathleen A. Farley (1698187), Margaret Fleming (2644384), Andrew Flick (3266184), Richard K. Frisbie (4109053), Justin Hall (549247), David Hepworth (1485040), Hannah Jones (475975), John D. Knafels (1811212), Steve Kortum (11888143), Frank E. Lovering (2499421), John P. Mathias (2143423), Sashi Mohan (11888146), Paul M. Morgan (2006197), Chuenlei Parng (11888149), Kevin Parris (1621801), Nick Pullen (521677), Franklin Schlerman (2381617), John Stansfield (5576258), Joseph W. Strohbach (3018849), Felix F. Vajdos (1348371), Fabien Vincent (1776697), Hong Wang (13528), Xiaolun Wang (2252662), Robert Webster (333847), Stephen W. Wright (1490587)
مصطلحات موضوعية: Biochemistry, Medicine, Pharmacology, Developmental Biology, Cancer, Infectious Diseases, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, throughput screening campaign, cyclic secondary amines, build target confidence, 3 b, 2 b, pyrimidine carboxamides derived, ketone moiety led, diaryl ketone series, vanin ‑ 1, pyrimidine carboxamides, suitable profile, preclinical development, crystallographic methods, crystal structures, adme properties
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7دورية أكاديمية
المؤلفون: Xiaolun Wang (2252662), Shelley Allen (1860448), James F. Blake (2039950), Vickie Bowcut (8408172), David M. Briere (5987522), Andrew Calinisan (8408166), Joshua R. Dahlke (11824182), Jay B. Fell (3022542), John P. Fischer (2983776), Robin J. Gunn (11824185), Jill Hallin (5987534), Jade Laguer (836370), J. David Lawson (1562440), James Medwid (11824188), Brad Newhouse (2201101), Phong Nguyen (694573), Jacob M. O’Leary (11824191), Peter Olson (824541), Spencer Pajk (11824194), Lisa Rahbaek (11134162), Mareli Rodriguez (11824197), Christopher R. Smith (1562425), Tony P. Tang (1845586), Nicole C. Thomas (1525276), Darin Vanderpool (2343520), Guy P. Vigers (5987549), James G. Christensen (156585), Matthew A. Marx (2134096)
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Pharmacology, Biotechnology, Cancer, Hematology, Infectious Diseases, Chemical Sciences not elsewhere classified, significant challenge due, high enough affinity, based activity improvement, mutant kras protein, g12d sup, solid tumors, selective kras, promising target, extensive structure, covalent interactions, bind kras
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8دورية أكاديمية
المؤلفون: Ping Gao, Xiaolun Wang, Hong Chen, Weihui Dai, Hong Ling
المصدر: Connection Science, Vol 33, Iss 2, Pp 321-340 (2021)
مصطلحات موضوعية: photo attractiveness, social interaction, mobile dating application, machine learning, Electronic computers. Computer science, QA75.5-76.95
العلاقة: http://dx.doi.org/10.1080/09540091.2020.1814204Test; https://doaj.org/toc/0954-0091Test; https://doaj.org/toc/1360-0494Test; https://doaj.org/article/6b701c5a77564521bad7d4b631113fbcTest
الإتاحة: https://doi.org/10.1080/09540091.2020.1814204Test
https://doaj.org/article/6b701c5a77564521bad7d4b631113fbcTest -
9
المؤلفون: Xinlin Yao, Yuxiang Chris Zhao, Shijie Song, Xiaolun Wang
المصدر: Journal of Documentation. 79:718-742
مصطلحات موضوعية: Library and Information Sciences, Information Systems
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10
المؤلفون: Jill Hallin, Vickie Bowcut, Andrew Calinisan, David M. Briere, Lauren Hargis, Lars D. Engstrom, Jade Laguer, James Medwid, Darin Vanderpool, Ella Lifset, David Trinh, Natalie Hoffman, Xiaolun Wang, J. David Lawson, Robin J. Gunn, Christopher R. Smith, Nicole C. Thomas, Matthew Martinson, Alex Bergstrom, Francis Sullivan, Karyn Bouhana, Shannon Winski, Leo He, Julio Fernandez-Banet, Adam Pavlicek, Jacob R. Haling, Lisa Rahbaek, Matthew A. Marx, Peter Olson, James G. Christensen
المصدر: Nature Medicine. 28:2171-2182
مصطلحات موضوعية: General Medicine, General Biochemistry, Genetics and Molecular Biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::d677a7e099fb8459d3aaad7bbf29b468Test
https://doi.org/10.1038/s41591-022-02007-7Test