المؤلفون: Melin, Esbjörn, Nanobashvili, Avtandil, Avdic, Una, Gøtzsche, Casper R., Andersson, My, Woldbye, David P.D., Kokaia, Merab

المصدر: Molecular Therapy - Methods and Clinical Development NanoLund: Centre for Nanoscience. 15:179-193

مصطلحات موضوعية: Medicin och hälsovetenskap, Medicinska och farmaceutiska grundvetenskaper, Neurovetenskaper, Medical and Health Sciences, Basic Medicine, Neurosciences

الوصول الحر: https://lup.lub.lu.se/record/e24142b7-b8a3-471f-9a80-d8a05a072085Test
http://dx.doi.org/10.1016/j.omtm.2019.09.004Test

المؤلفون: Kjær, Christina, Palasca, Oana, Barzaghi, Guido, Bak, Lasse K., Durhuus, Rúna K.J., Jakobsen, Emil, Pedersen, Louise, Bartels, Emil D., Woldbye, David P.D., Pinborg, Lars H., Jensen, Lars Juhl

المصدر: Kjær , C , Palasca , O , Barzaghi , G , Bak , L K , Durhuus , R K J , Jakobsen , E , Pedersen , L , Bartels , E D , Woldbye , D P D , Pinborg , L H & Jensen , L J 2023 , ' Differential Expression of the β3 Subunit of Voltage-Gated Ca 2+ Channel in Mesial Temporal Lobe Epilepsy ' , Molecular Neurobiology , vol. 60 , pp. 5755–5769 . https://doi.org/10.1007/s12035-023-03426-4Test

مصطلحات موضوعية: CACNB3, Mesial temporal lobe epilepsy, mTLE, Target validation, Transcriptome analysis, Unbiased drug target identification

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1007/s12035-023-03426-4Test
https://curis.ku.dk/portal/da/publications/differential-expression-of-the-3-subunit-of-voltagegated-ca2-channel-in-mesial-temporal-lobe-epilepsyTest(6a906ce9-fb80-461e-8420-ae2dcaed13da).html
https://curis.ku.dk/ws/files/367836758/s12035_023_03426_4.pdfTest

المؤلفون: Melin, Esbjörn, Andersson, My, Gøtzsche, Casper R., Wickham, Jenny, Huang, Yuzhe, Szczygiel, Julia Alicja, Boender, Arnie, Christiansen, Søren H., Pinborg, Lars, Woldbye, David P.D., Kokaia, Merab

المصدر: Melin , E , Andersson , M , Gøtzsche , C R , Wickham , J , Huang , Y , Szczygiel , J A , Boender , A , Christiansen , S H , Pinborg , L , Woldbye , D P D & Kokaia , M 2023 , ' Combinatorial gene therapy for epilepsy : Gene sequence positioning and AAV serotype influence expression and inhibitory effect on seizures ' , Gene Therapy , vol. 30 , pp. 649-658 . https://doi.org/10.1038/s41434-023-00399-wTest

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1038/s41434-023-00399-wTest
https://curis.ku.dk/portal/da/publications/combinatorial-gene-therapy-for-epilepsyTest(d37abcc1-df13-4265-846b-7be0493814f3).html
https://curis.ku.dk/ws/files/365823315/s41434_023_00399_w_3_.pdfTest

المؤلفون: Ledri, Marco, Sørensen, Andreas T., Kokaia, Merab, Woldbye, David P.D., Gøtzsche, Casper R.

المصدر: Frontiers in Molecular Neuroscience. 14

مصطلحات موضوعية: adeno-associated virus vector, central nervous system, CRISPR, gene therapy, genome editing, proof-of-concept, Medicin och hälsovetenskap, Medicinska och farmaceutiska grundvetenskaper, Neurovetenskaper, Medical and Health Sciences, Basic Medicine, Neurosciences

الوصول الحر: https://lup.lub.lu.se/record/d70e413a-8d77-422a-ac07-570fbe2925f0Test
http://dx.doi.org/10.3389/fnmol.2021.778134Test

المؤلفون: Stokholm, Kathrine, Thomsen, Majken Borup, Phan, Jenny Ann, Møller, Line K., Bay-Richter, Cecilie, Christiansen, Søren H., Woldbye, David P.D., Romero-Ramos, Marina, Landau, Anne M.

المصدر: Stokholm , K , Thomsen , M B , Phan , J A , Møller , L K , Bay-Richter , C , Christiansen , S H , Woldbye , D P D , Romero-Ramos , M & Landau , A M 2021 , ' α-Synuclein Overexpression Increases Dopamine D2/3 Receptor Binding and Immune Activation in a Model of Early Parkinson’s Disease ' , Biomedicines , vol. 9 , no. 12 , 1876 . https://doi.org/10.3390/biomedicines9121876Test

مصطلحات موضوعية: Adeno-associated viral vectors, Autoradiography, Dopamine, Neuroinflam-mation, Parkinson’s disease, Synaptic vesicle glycoprotein 2A, α-synuclein

العلاقة: https://pure.au.dk/portal/da/publications/synuclein-overexpression-increases-dopamine-d23-receptor-binding-and-immune-activation-in-a-model-of-early-parkinsons-diseaseTest(ad476cb4-6e64-4541-839a-03d1e75ba88e).html

الإتاحة: https://doi.org/10.3390/biomedicines9121876Test
https://pure.au.dk/portal/da/publications/synuclein-overexpression-increases-dopamine-d23-receptor-binding-and-immune-activation-in-a-model-of-early-parkinsons-diseaseTest(ad476cb4-6e64-4541-839a-03d1e75ba88e).html

المؤلفون: Forstner, Andreas J., Awasthi, Swapnil, Wolf, Christiane, Maron, Eduard, Erhardt, Angelika, Czamara, Darina, Eriksson, Elias, Lavebratt, Catharina, Allgulander, Christer, Friedrich, Nina, Becker, Jessica, Hecker, Julian, Rambau, Stefanie, Conrad, Rupert, Geiser, Franziska, McMahon, Francis J., Moebus, Susanne, Hess, Timo, Buerfent, Benedikt C., Hoffmann, Per, Herms, Stefan, Heilmann-Heimbach, Stefanie, Kockum, Ingrid, Olsson, Tomas, Alfredsson, Lars, Weber, Heike, Alpers, Georg W., Arolt, Volker, Fehm, Lydia, Fydrich, Thomas, Gerlach, Alexander L., Hamm, Alfons, Kircher, Tilo, Pané-Farré, Christiane A., Pauli, Paul, Rief, Winfried, Ströhle, Andreas, Plag, Jens, Lang, Thomas, Wittchen, Hans Ulrich, Mattheisen, Manuel, Meier, Sandra, Metspalu, Andres, Domschke, Katharina, Reif, Andreas, Hovatta, Iiris, Lindefors, Nils, Andersson, Evelyn, Schalling, Martin, Mbarek, Hamdi, Milaneschi, Yuri, de Geus, Eco J.C., Boomsma, Dorret I., Penninx, Brenda W.J.H., Thorgeirsson, Thorgeir E., Steinberg, Stacy, Stefansson, Kari, Stefansson, Hreinn, Müller-Myhsok, Bertram, Hansen, Thomas Folkmann, Børglum, Anders D., Werge, Thomas, Mortensen, Preben Bo, Nordentoft, Merete, Hougaard, David M., Hultman, Christina M., Sullivan, Patrick F., Nöthen, Markus M., Woldbye, David P.D., Mors, Ole, Binder, Elisabeth B., Rück, Christian, Ripke, Stephan, Deckert, Jürgen, Schumacher, Johannes

المصدر: Forstner , A J , Awasthi , S , Wolf , C , Maron , E , Erhardt , A , Czamara , D , Eriksson , E , Lavebratt , C , Allgulander , C , Friedrich , N , Becker , J , Hecker , J , Rambau , S , Conrad , R , Geiser , F , McMahon , F J , Moebus , S , Hess , T , Buerfent , B C , Hoffmann , P , Herms , S , Heilmann-Heimbach , S , Kockum , I , Olsson , T , ....

العلاقة: https://pure.au.dk/portal/da/publications/genomewide-association-study-of-panic-disorder-reveals-genetic-overlap-with-neuroticism-and-depressionTest(147eda55-ea2c-4dc1-956f-3e3a3cedb007).html

الإتاحة: https://doi.org/10.1038/s41380-019-0590-2Test
https://pure.au.dk/portal/da/publications/genomewide-association-study-of-panic-disorder-reveals-genetic-overlap-with-neuroticism-and-depressionTest(147eda55-ea2c-4dc1-956f-3e3a3cedb007).html

المؤلفون: Jensen, Thomas Leth, Gøtzsche, Casper René, Woldbye, David P.D.

المصدر: Jensen , T L , Gøtzsche , C R & Woldbye , D P D 2021 , ' Current and Future Prospects for Gene Therapy for Rare Genetic Diseases Affecting the Brain and Spinal Cord ' , Frontiers in Molecular Neuroscience , vol. 14 , 695937 . https://doi.org/10.3389/fnmol.2021.695937Test

مصطلحات موضوعية: central nervous system, clinical trials, gene therapy, personalized medicine, rare diseases, spinal cord, spinal muscular atrophy, viral vectors

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.3389/fnmol.2021.695937Test
https://curis.ku.dk/portal/da/publications/current-and-future-prospects-for-gene-therapy-for-rare-genetic-diseases-affecting-the-brain-and-spinal-cordTest(bb75e397-9217-4980-80d4-87b028c0172e).html
https://curis.ku.dk/ws/files/283003220/Current_and_Future_Prospects_for_Gene_Therapy_for_Rare_Genetic_Diseases_Affecting_the_Brain_and_Spinal_Cord.pdfTest

المؤلفون: Hundahl, Cecilie, Kotzbeck, Petra, Burm, Hayley B., Christiansen, Søren H., Torz, Lola, Helge, Aske W., Madsen, Martin P., Ratner, Cecilia, Serup, Annette K., Thompson, Jonatan J., Eichmann, Thomas O., Pers, Tune H., Woldbye, David P.D., Piomelli, Daniele, Kiens, Bente, Zechner, Rudolf, Skov, Louise J., Holst, Birgitte

المساهمون: Novo Nordisk Fonden, Novo Nordisk Foundation Center for Basic Metabolic Research

المصدر: Molecular Metabolism ; volume 47, page 101174 ; ISSN 2212-8778

مصطلحات موضوعية: Cell Biology, Molecular Biology

الإتاحة: https://doi.org/10.1016/j.molmet.2021.101174Test
https://api.elsevier.com/content/article/PII:S2212877821000144?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2212877821000144?httpAccept=text/plainTest

المؤلفون: Wickham, Jenny, Ledri, Marco, Bengzon, Johan, Jespersen, Bo, Pinborg, Lars H., Englund, Elisabet, Woldbye, David P.D., Andersson, My, Kokaia, Merab

المصدر: Scientific Reports StemTherapy: National Initiative on Stem Cells for Regenerative Therapy MultiPark: Multidisciplinary research focused on Parkinson´s disease NanoLund: Centre for Nanoscience. 9(1)

مصطلحات موضوعية: Medicin och hälsovetenskap, Klinisk medicin, Neurologi, Medical and Health Sciences, Clinical Medicine, Neurology

الوصول الحر: https://lup.lub.lu.se/record/69df5f5b-c695-4b61-ad48-49720063713bTest
http://dx.doi.org/10.1038/s41598-019-56062-1Test

المؤلفون: Axelsen, Tobias M., Woldbye, David P.D.

المصدر: Axelsen , T M & Woldbye , D P D 2018 , ' Gene therapy for Parkinson's disease, an update ' , Journal of Parkinson's Disease , vol. 8 , no. 2 , pp. 195-215 . https://doi.org/10.3233/JPD-181331Test

مصطلحات موضوعية: BDNF, CDNF, chemogenetics, dopamine, GAD, GDNF, Gene therapy, genome editing, MANF, neurotrophic factors, NRTN, optogenetics, Parkinson's disease targets

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.3233/JPD-181331Test
https://curis.ku.dk/portal/da/publications/gene-therapy-for-parkinsons-disease-an-updateTest(ea3c9b65-7e5c-46c7-8065-af245b069b1b).html
https://curis.ku.dk/ws/files/210829325/Gene_therapy_for_Parkinson_s_disease_an_update.pdfTest