المؤلفون: Fu, Dong-Jun, Zhang, Li, Song, Jian, Mao, Ruo-Wang, Zhao, Ruo-Han, Liu, Ying-Chao, Hou, Yu-Hui, Li, Jia-Huan, Yang, Jia-Jia, Jin, Cheng-Yun, Li, Ping, Zi, Xiao-Lin, Liu, Hong-Min, Zhang, Sai-Yang, Zhang, Yan-Bing

المصدر: European journal of medicinal chemistry. 127

مصطلحات موضوعية: Antineoplastic Agents: chemical synthesis, chemistry, pharmacology, Apoptosis: drug effects, Cell Line, Tumor, Cell Movement: drug effects, Cell Proliferation: drug effects, Chemistry Techniques, Synthetic, Dose-Response Relationship, Drug, Drug Design, Drug Screening Assays, Antitumor, Drug Synergism, G1 Phase Cell Cycle Checkpoints: drug effects, Humans, Isoflavones: chemical synthesis, chemistry, pharmacology, MAP Kinase Signaling System: drug effects, Structure-Activity Relationship, Thiocarbamates: chemistry, Wnt Signaling Pathway: drug effects

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/2jw7m037Test

المؤلفون: Lu, Chanyi, Lin, Xiaoli, Yamashita, Jumpei, Xi, Ranhui, Zhou, Minliang, Zhang, Yali V., Wang, Hong, Margolskee, Robert F., Koo, Bon Kyoung, Clevers, Hans, Matsumoto, Ichiro, Jiang, Peihua

المساهمون: Hubrecht Institute with UMC

مصطلحات موضوعية: LGR5, R-spondin, RNF43, taste stem cells, WNT, ZNRF3, Epithelium/metabolism, Mice, Inbred C57BL, Wnt Signaling Pathway/drug effects, Ubiquitin-Protein Ligases/deficiency, Knockout, Taste Buds/metabolism, Animals, Tongue/cytology, Benzeneacetamides/pharmacology, Taste/physiology, Stem Cells/cytology, Glossopharyngeal Nerve/surgery, Pyridines/pharmacology, Genetics, Biochemistry, Cell Biology, Developmental Biology, Journal Article, Research Support, N.I.H., Extramural

وصف الملف: application/pdf

العلاقة: https://dspace.library.uu.nl/handle/1874/446394Test

الإتاحة: https://dspace.library.uu.nl/handle/1874/446394Test

المؤلفون: Miete, Cezanne, Solis, Gonzalo, Koval, Alexey, Brückner, Martina, Katanaev, Vladimir, Behrens, Jürgen, Bernkopf, Dominic B

المصدر: ISSN: 2041-1723 ; Nature communications, vol. 13, no. 1 (2022) 674.

مصطلحات موضوعية: info:eu-repo/classification/ddc/612, Animals, Axin Protein / genetics, Axin Protein / metabolism, Cell Line, Tumor, Cell Proliferation / drug effects, Cell Proliferation / genetics, Colorectal Neoplasms / genetics, Colorectal Neoplasms / metabolism, Colorectal Neoplasms / pathology, Female, GTP-Binding Protein alpha Subunit, Gi2 / genetics, Gene Expression Regulation, Neoplastic, Guanabenz / pharmacology, HEK293 Cells, Humans, Mice, Inbred BALB C, Inbred C57BL, Nude, Mutation, Wnt Signaling Pathway / drug effects, Wnt Signaling Pathway / genetics, Xenograft Model Antitumor Assays / methods, Beta Catenin / genetics, Beta Catenin / metabolism, GTP-Binding Protein alpha Subunit,Gi2/metabolism

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/35115535; https://archive-ouverte.unige.ch/unige:160123Test; unige:160123

الإتاحة: https://doi.org/10.1038/s41467-022-28286-9Test
https://archive-ouverte.unige.ch/unige:160123Test

المساهمون: Pu-Hyeon Cha, Jeong-Ha Hwang, Dong-Kyu Kwak, Eunjin Koh, Kyung-Sup Kim, Kang-Yell Choi, Koh, Eun Jin

مصطلحات موضوعية: Animals, Carrier Proteins / genetics, Carrier Proteins / metabolism, Colorectal Neoplasms / genetics, Colorectal Neoplasms / metabolism, Genes, APC, Heterografts, Humans, L-Lactate Dehydrogenase / genetics, L-Lactate Dehydrogenase / metabolism, Male, Membrane Proteins / genetics, Membrane Proteins / metabolism, Mice, Inbred BALB C, Nude, Mitochondrial Proton-Translocating ATPases / metabolism, Neoplasm Proteins / genetics, Neoplasm Proteins / metabolism, Proteomics, Thiazolidines / pharmacology, Thyroid Hormones / genetics, Thyroid Hormones / metabolism, Tissue Array Analysis, Warburg Effect, Oncologic, Wnt Signaling Pathway* / drug effects, Wnt Signaling Pathway* / genetics, beta Catenin / metabolism

العلاقة: BRITISH JOURNAL OF CANCER; J00406; OAK-2022-05235; OAK-2022-05236; https://ir.ymlib.yonsei.ac.kr/handle/22282913/191042Test; T9992022449; BRITISH JOURNAL OF CANCER, Vol.124(3) : 634-644, 2021-02

الإتاحة: https://doi.org/10.1038/s41416-020-01118-7Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/191042Test

المساهمون: Hyun-Yi Kim, Shujin Li, Dong-Joon Lee, Jin Hoo Park, Takashi Muramatsu, Hidemitsu Harada, Young-Soo Jung, Han-Sung Jung, Park, Jin Hoo

مصطلحات موضوعية: Ameloblastoma / metabolism, Ameloblastoma / pathology, Animals, Cell Culture Techniques, Cell Line, Tumor, Cell Proliferation / drug effects, Cell Size / drug effects, Down-Regulation / drug effects, Humans, Lithium Chloride / pharmacology, Mice, Nude, Neoplastic Stem Cells / cytology, Neoplastic Stem Cells / metabolism, SOXB1 Transcription Factors / metabolism, Valproic Acid / pharmacology, Wnt Signaling Pathway / drug effects, beta Catenin / metabolism, Wnt signalling, ameloblastoma, cancer stem cell

العلاقة: CELL PROLIFERATION; J00487; OAK-2021-08027; https://ir.ymlib.yonsei.ac.kr/handle/22282913/186989Test; T202104906; CELL PROLIFERATION, Vol.54(7) : e13073, 2021-07

الإتاحة: https://doi.org/10.1111/cpr.13073Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/186989Test

المساهمون: Yong-Hee Cho, Eun Ji Ro, Jeong-Su Yoon, Tomohiro Mizutani, Dong-Woo Kang, Jong-Chan Park, Tae Il Kim, Hans Clevers, Kang-Yell Choi, Kim, Tae Il

مصطلحات موضوعية: Animals, Antineoplastic Agents / administration & dosage, Antineoplastic Agents / pharmacology, Cell Line, Tumor, Colorectal Neoplasms / drug therapy, Colorectal Neoplasms / metabolism, Colorectal Neoplasms / pathology, Fluorouracil / pharmacology, HCT116 Cells, Humans, Mice, Inbred NOD, Nude, SCID, Transgenic, Neoplastic Stem Cells / drug effects, Neoplastic Stem Cells / metabolism, Neoplastic Stem Cells / pathology, Organoids / drug effects, Organoids / metabolism, Organoids / pathology, Pyrazines / administration & dosage, Pyridines / administration & dosage, Receptors, G-Protein-Coupled / genetics, G-Protein-Coupled / metabolism, Tumor Suppressor Protein p53 / metabolism, Wnt Signaling Pathway / drug effects, Wnt3 Protein / genetics

العلاقة: NATURE COMMUNICATIONS; J02293; OAK-2022-03542; https://ir.ymlib.yonsei.ac.kr/handle/22282913/189955Test; T9992020176; NATURE COMMUNICATIONS, Vol.11(1) : 5321, 2020-10

الإتاحة: https://doi.org/10.1038/s41467-020-19173-2Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/189955Test

المؤلفون: Cho, Yong-Hee, Ro, Eun Ji, Yoon, Jeong-Su, Mizutani, Tomohiro, Kang, Dong-Woo, Park, Jong-Chan, Il Kim, Tae, Clevers, Hans, Choi, Kang-Yell

المصدر: Cho , Y-H , Ro , E J , Yoon , J-S , Mizutani , T , Kang , D-W , Park , J-C , Il Kim , T , Clevers , H & Choi , K-Y 2020 , ' 5-FU promotes stemness of colorectal cancer via p53-mediated WNT/β-catenin pathway activation ' , Nature Communications , vol. 11 , no. 1 , pp. 5321 . https://doi.org/10.1038/s41467-020-19173-2Test

مصطلحات موضوعية: Animals, Antineoplastic Agents/administration & dosage, Cell Line, Tumor, Colorectal Neoplasms/drug therapy, Fluorouracil/pharmacology, HCT116 Cells, Humans, Mice, Inbred NOD, Nude, SCID, Transgenic, Neoplastic Stem Cells/drug effects, Organoids/drug effects, Pyrazines/administration & dosage, Pyridines/administration & dosage, Receptors, G-Protein-Coupled/genetics, Tumor Suppressor Protein p53/metabolism, Wnt Signaling Pathway/drug effects, Wnt3 Protein/genetics, Xenograft Model Antitumor Assays, beta Catenin/metabolism

العلاقة: https://pure.knaw.nl/portal/en/publications/de483e27-9a68-49de-bf37-80bb92ac9c00Test

الإتاحة: https://doi.org/10.1038/s41467-020-19173-2Test
https://doi.org/20.500.11755/de483e27-9a68-49de-bf37-80bb92ac9c00Test
https://pure.knaw.nl/portal/en/publications/de483e27-9a68-49de-bf37-80bb92ac9c00Test
https://hdl.handle.net/20.500.11755/de483e27-9a68-49de-bf37-80bb92ac9c00Test

المؤلفون: Ahmed, K., Koval, A., Xu, J., Bodmer, A., Katanaev, V.L.

المصدر: Cancer letters, vol. 449, pp. 45-55

مصطلحات موضوعية: Animals, Antineoplastic Combined Chemotherapy Protocols/administration & dosage, Antineoplastic Combined Chemotherapy Protocols/therapeutic use, Cell Line, Tumor, Cell Proliferation/drug effects, Cell Survival/drug effects, Clofazimine/administration & dosage, Clofazimine/pharmacology, Doxorubicin/administration & dosage, Doxorubicin/therapeutic use, Drug Repositioning, Female, Gene Expression Regulation, Neoplastic/drug effects, Humans, Mice, Neoplasm Transplantation, Triple Negative Breast Neoplasms/drug therapy, Triple Negative Breast Neoplasms/metabolism, Wnt Signaling Pathway/drug effects, Clofazimine, Drug combination, Targeted therapy, Triple-negative breast cancer, Wnt signaling

وصف الملف: application/pdf

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/30771433; info:eu-repo/semantics/altIdentifier/eissn/1872-7980; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_E7565389B4377; https://serval.unil.ch/notice/serval:BIB_E7565389B437Test; urn:issn:0304-3835; https://serval.unil.ch/resource/serval:BIB_E7565389B437.P001/REF.pdfTest; http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_E7565389B4377Test

الإتاحة: https://doi.org/10.1016/j.canlet.2019.02.018Test
https://serval.unil.ch/notice/serval:BIB_E7565389B437Test
https://serval.unil.ch/resource/serval:BIB_E7565389B437.P001/REF.pdfTest
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_E7565389B4377Test

المساهمون: College of Medicine, Dept. of Internal Medicine, Jiwon Choi, Kyungro Lee, Myeongmo Kang, Sung-Kil Lim, Kyoung Tai No, Lim, Sung Kil

مصطلحات موضوعية: Bone Morphogenetic Proteins/antagonists & inhibitors, Bone Morphogenetic Proteins/chemistry, Dose-Response Relationship, Drug, Drug Discovery, Genetic Markers, Humans, Low Density Lipoprotein Receptor-Related Protein-5/antagonists & inhibitors, Low Density Lipoprotein Receptor-Related Protein-5/chemistry, Molecular Docking Simulation, Molecular Structure, Quinoxalines/chemical synthesis, Quinoxalines/chemistry, Quinoxalines/pharmacology, Structure-Activity Relationship, Wnt Signaling Pathway/drug effects, LRP5/6-sclerostin interaction, Osteoporosis, Structure-activity relationships, Virtual screening, Wnt/棺-catenin signalling pathway

العلاقة: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS; J00326; OAK-2018-04177; https://ir.ymlib.yonsei.ac.kr/handle/22282913/163516Test; T201803044; BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, Vol.28(6) : 1116-1121, 2018

الإتاحة: https://doi.org/10.1016/j.bmcl.2018.01.050Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/163516Test

المؤلفون: Akcora, Büsra Öztürk, Storm, Gert, Bansal, Ruchi

المساهمون: Afd Pharmaceutics, Pharmaceutics

مصطلحات موضوعية: 3T3 Cells, Animals, Bridged Bicyclo Compounds, Heterocyclic/pharmacology, CREB-Binding Protein/antagonists & inhibitors, Cells, Cultured, Hepatic Stellate Cells/drug effects, Humans, Liver/cytology, Liver Cirrhosis/drug therapy, Male, Mice, Inbred C57BL, Pyrimidinones/pharmacology, Stromal Cells/drug effects, Wnt Signaling Pathway/drug effects, beta Catenin/antagonists & inhibitors

وصف الملف: image/pdf

العلاقة: https://dspace.library.uu.nl/handle/1874/375480Test

الإتاحة: https://dspace.library.uu.nl/handle/1874/375480Test