المؤلفون: Harrington, Lucas B, Ma, Enbo, Chen, Janice S, Witte, Isaac P, Gertz, Dov, Paez-Espino, David, Al-Shayeb, Basem, Kyrpides, Nikos C, Burstein, David, Banfield, Jillian F, Doudna, Jennifer A

المصدر: Molecular Cell. 79(3)

مصطلحات موضوعية: Biochemistry and Cell Biology, Bioinformatics and Computational Biology, Biological Sciences, Infectious Diseases, Genetics, Underpinning research, 1.1 Normal biological development and functioning, Bacteria, Bacterial Proteins, Base Sequence, CRISPR-Cas Systems, Clustered Regularly Interspaced Short Palindromic Repeats, DNA, Bacterial, Endodeoxyribonucleases, Escherichia coli, Genome, Bacterial, Nucleic Acid Conformation, Phylogeny, RNA, Bacterial, RNA, Guide, Kinetoplastida, RNA, Small Untranslated, Sequence Alignment, Sequence Homology, Nucleic Acid, CRISPR-cas, Candidate Phyla Radiation (CPR) bacteria, Cas12c, Cas12d, RuvC nuclease domain, crRNA, scoutRNA, tracrRNA, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences, Health sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/5rs657fnTest

المؤلفون: Cofsky, Joshua, Karandur, Deepti, Huang, Carolyn, Witte, Isaac, Kuriyan, John, Doudna, Jennifer

مصطلحات موضوعية: CRISPR, E. coli, R-loop, RNA, biochemistry, chemical biology, deoxyribonuclease, genome editing, Bacterial Proteins, CRISPR-Associated Proteins, CRISPR-Cas Systems, DNA, DNA Breaks, Double-Stranded, Endodeoxyribonucleases, Escherichia coli, Gene Editing, R-Loop Structures, RNA, Guide, CRISPR-Cas Systems

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/2d03c4w3Test

المؤلفون: Cofsky, Joshua C, Karandur, Deepti, Huang, Carolyn J, Witte, Isaac P, Kuriyan, John, Doudna, Jennifer A

مصطلحات موضوعية: Biochemistry and Cell Biology, Bioinformatics and Computational Biology, Biological Sciences, Genetics, Prevention, 1.1 Normal biological development and functioning, Underpinning research, Generic health relevance, Bacterial Proteins, CRISPR-Associated Proteins, CRISPR-Cas Systems, DNA, DNA Breaks, Double-Stranded, Endodeoxyribonucleases, Escherichia coli, Gene Editing, R-Loop Structures, RNA, Guide, Kinetoplastida, CRISPR, E. coli, R-loop, RNA, biochemistry, chemical biology, deoxyribonuclease, genome editing, Biological sciences, Biomedical and clinical sciences, Health sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/6sq1v35sTest

المؤلفون: Davis, Jessie R., Wang, Xiao, Witte, Isaac P., Huang, Tony P., Levy, Jonathan M., Raguram, Aditya, Banskota, Samagya, Seidah, Nabil G., Musunuru, Kiran, Liu, David R.

المصدر: Nature Biomedical Engineering ; volume 6, issue 11, page 1317-1317 ; ISSN 2157-846X

مصطلحات موضوعية: Computer Science Applications, Biomedical Engineering, Medicine (miscellaneous), Bioengineering, Biotechnology

الإتاحة: https://doi.org/10.1038/s41551-022-00934-xTest
https://www.nature.com/articles/s41551-022-00934-x.pdfTest
https://www.nature.com/articles/s41551-022-00934-xTest

المؤلفون: Davis, Jessie R., Wang, Xiao, Witte, Isaac P., Huang, Tony P., Levy, Jonathan M., Raguram, Aditya, Banskota, Samagya, Seidah, Nabil G., Musunuru, Kiran, Liu, David R.

المساهمون: U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases, U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences, U.S. Department of Health & Human Services | NIH | National Human Genome Research Institute, Howard Hughes Medical Institute, Bill and Melinda Gates Foundation

المصدر: Nature Biomedical Engineering ; volume 6, issue 11, page 1272-1283 ; ISSN 2157-846X

مصطلحات موضوعية: Computer Science Applications, Biomedical Engineering, Medicine (miscellaneous), Bioengineering, Biotechnology

الإتاحة: https://doi.org/10.1038/s41551-022-00911-4Test
https://www.nature.com/articles/s41551-022-00911-4.pdfTest
https://www.nature.com/articles/s41551-022-00911-4Test

المؤلفون: Harrington, Lucas B., Burstein, David, Chen, Janice S., Paez-Espino, David, Ma, Enbo, Witte, Isaac P., Cofsky, Joshua C., Kyrpides, Nikos C., Banfield, Jillian F., Doudna, Jennifer A.

المصدر: Science, 2018 Nov . 362(6416), 839-842.

الوصول الحر: https://www.jstor.org/stable/26569337Test

المؤلفون: Garst, Emma H., Lee, Hwayoung, Das, Tandrila, Bhattacharya, Shibani, Percher, Avital, Wiewiora, Rafal, Witte, Isaac P., Li, Yumeng, Peng, Tao, Im, Wonpil, Hang, Howard C.

المساهمون: Division of Molecular and Cellular Biosciences, Science, Technology and Innovation Commission of Shenzhen Municipality, National Natural Science Foundation of China, National Institute of General Medical Sciences

المصدر: ACS Chemical Biology ; volume 16, issue 5, page 844-856 ; ISSN 1554-8929 1554-8937

الإتاحة: https://doi.org/10.1021/acschembio.1c00013Test

المؤلفون: Cofsky, Joshua C, Karandur, Deepti, Huang, Carolyn J, Witte, Isaac P, Kuriyan, John, Doudna, Jennifer A

الإتاحة: https://doi.org/10.7554/elife.55143.sa2Test

المؤلفون: Harrington, Lucas B., Burstein, David, Chen, Janice S., Paez-Espino, David, Ma, Enbo, Witte, Isaac P., Cofsky, Joshua C., Kyrpides, Nikos C., Banfield, Jillian F., Doudna, Jennifer A.

مصطلحات موضوعية: 59 BASIC BIOLOGICAL SCIENCES

وصف الملف: application/pdf

العلاقة: http://www.osti.gov/servlets/purl/1563978Test; https://www.osti.gov/biblio/1563978Test; https://doi.org/10.1126/science.aav4294Test

الإتاحة: https://doi.org/10.1126/science.aav4294Test
http://www.osti.gov/servlets/purl/1563978Test
https://www.osti.gov/biblio/1563978Test

المؤلفون: Harrington, Lucas B., Burstein, David, Chen, Janice S., Paez-Espino, David, Ma, Enbo, Witte, Isaac P., Cofsky, Joshua C., Kyrpides, Nikos C., Banfield, Jillian F., Doudna, Jennifer A.

وصف الملف: application/pdf

العلاقة: http://www.osti.gov/servlets/purl/1482289Test; https://www.osti.gov/biblio/1482289Test; https://doi.org/10.1126/science.aav4294Test

الإتاحة: https://doi.org/10.1126/science.aav4294Test
http://www.osti.gov/servlets/purl/1482289Test
https://www.osti.gov/biblio/1482289Test