دورية أكاديمية
Contraceptive and Infertility Target DataBase: a contraceptive drug development tool for targeting and analysis of human reproductive specific tissues†
| العنوان: | Contraceptive and Infertility Target DataBase: a contraceptive drug development tool for targeting and analysis of human reproductive specific tissues† |
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| المؤلفون: | Sinha, Subarna, Knapp, Merrill, Pywtorak, John, McCain, Greg, Wingerden, Kenneth, VanDervoort, Colin, Gondek, J Mark, Madrid, Peter, Parman, Toufan, Gerrard, Stephen, Long, Jill E, Blithe, Diana L, Moss, Stuart, Lee, Min S |
| المساهمون: | National Institutes of Health |
| المصدر: | Biology of Reproduction ; volume 105, issue 6, page 1366-1374 ; ISSN 0006-3363 1529-7268 |
| بيانات النشر: | Oxford University Press (OUP) |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Cell Biology, General Medicine, Reproductive Medicine |
| الوصف: | The long and challenging drug development process begins with discovery biology for the selection of an appropriate target for a specific indication. Target is a broad term that can be applied to a range of biological entities such as proteins, genes, and ribonucleic acids (RNAs). Although there are numerous databases available for mining biological entities, publicly available searchable, downloadable databases to aid in target selection for a specific disease or indication (e.g., developing contraceptives and infertility treatments) are limited. We report the development of the Contraceptive and Infertility Target DataBase (https://www.citdbase.orgTest), which provides investigators an interface to mine existing transcriptomic and proteomic resources to identify high-quality contraceptive/infertility targets. The development of similar databases is applicable to the identification of targets for other diseases and conditions. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1093/biolre/ioab172 |
| DOI: | 10.1093/biolre/ioab172/40535792/ioab172.pdf |
| الإتاحة: | https://doi.org/10.1093/biolre/ioab172Test https://academic.oup.com/biolreprod/article-pdf/105/6/1366/42495922/ioab172.pdfTest |
| رقم الانضمام: | edsbas.CB4A58EF |
| قاعدة البيانات: | BASE |
| DOI: | 10.1093/biolre/ioab172 |
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