يعرض 1 - 10 نتائج من 35 نتيجة بحث عن '"William K. Sonnenburg"', وقت الاستعلام: 0.89s تنقيح النتائج
  1. 1
    دورية أكاديمية
    GPIHBP1 stabilizes lipoprotein lipase and prevents its inhibition by angiopoietin-like 3 and angiopoietin-like 4

    المؤلفون: William K. Sonnenburg, Daiguan Yu, E-Chiang Lee, Wei Xiong, Gennady Gololobov, Billie Key, Jason Gay, Nat Wilganowski, Yi Hu, Sharon Zhao, Matthias Schneider, Zhi-Ming Ding, Brian P. Zambrowicz, Greg Landes, David R. Powell, Urvi Desai

    المصدر: Journal of Lipid Research, Vol 50, Iss 12, Pp 2421-2429 (2009)

    مصطلحات موضوعية: glycosylphosphatidylinositol-anchored HDL-binding protein, knockout mice, monoclonal antibodies, hypertriglyceridemia, chylomicronemia, ANGPTL4-neutralizing monoclonal antibody, Biochemistry, QD415-436

    وصف الملف: electronic resource

    العلاقة: http://www.sciencedirect.com/science/article/pii/S0022227520306659Test; https://doaj.org/toc/0022-2275Test

    الوصول الحر: https://doaj.org/article/212a1662bcbd4d06a66de9a15ab677adTest

    View record in DOAJ النص الكامل

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  2. 2
    Characterization of Specific N-α-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library

    المؤلفون: Paul G. Richardson, Xiaoyun Meng, Karen A. Maegley, A.E. Stewart, Pei-Pei Kung, Jose L Montano, Ya-Li Deng, Jinqiao Wan, Michael R. Gehring, Jordan L. Meier, Brigitte S Naughton, Stephan Grant, Dou Dengfeng, Chakrapani Subramanyam, Anthony R. Harris, Samantha Elizabeth Greasley, Barry A. Morgan, Wen Yan, Xuemin Cheng, Prakash B. Palde, William K Sonnenburg, Junli Feng, Chen Qiuxia, Thomas A Paul, Gary M. Gallego, Sylvie K. Sakata, Sergei Timofeevski, Patrick Bingham, Benjamin J. Burke, Alex Shaginian

    المصدر: ACS Med Chem Lett

    مصطلحات موضوعية: chemistry.chemical_classification, 010405 organic chemistry, Chemistry, Stereochemistry, Organic Chemistry, Target engagement, Substrate (chemistry), 01 natural sciences, Biochemistry, Cocrystal, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Enzyme, Mechanism of action, Acetyltransferase, Drug Discovery, medicine, A-DNA, medicine.symptom, Selectivity

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c0b93599ae79500f98919ddfa6e48aaTest
    https://doi.org/10.1021/acsmedchemlett.0c00029Test


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  3. 3
    Inhibition of Sphingosine 1-Phosphate Lyase for the Treatment of Rheumatoid Arthritis: Discovery of (E)-1-(4-((1R,2S,3R)-1,2,3,4-Tetrahydroxybutyl)-1H-imidazol-2-yl)ethanone Oxime (LX2931) and (1R,2S,3R)-1-(2-(Isoxazol-3-yl)-1H-imidazol-4-yl)butane-1,2,3,4-tetraol (LX2932)

    المؤلفون: Alan Wilson, Iris B. Owusu, Boteju Lakmal W, Saadat Aleem, Philip Manton Brown, Jack Yan, Theodore C. Jessop, David J. Augeri, Suman Layek, Zhong Lai, S. David Kimball, Jill Hazelwood, William Heydorn, Kenneth G. Carson, Tamas Oravecz, Liam Moran, Suma Gopinathan, Haiming Zhang, Michael S. Donoviel, Amr Nouraldeen, William K. Sonnenburg, Jeffrey T. Bagdanoff, Jeffrey A. Kramer, Alan Main, Barbara Brooks, Li Dong, James E. Tarver, Padmaja Yalamanchili, Kenny Frazier, Marianne Carlsen, Mark S. Bednarz

    المصدر: Journal of Medicinal Chemistry. 53:8650-8662

    مصطلحات موضوعية: Sphingosine, Chemistry, Arthritis, Pharmacology, medicine.disease, Oxime, Lyase, chemistry.chemical_compound, In vivo, Oral administration, Rheumatoid arthritis, Drug Discovery, medicine, Molecular Medicine, Structure–activity relationship

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::c87e00a9781c267b0a4f8d1324759661Test
    https://doi.org/10.1021/jm101183pTest


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  4. 4
    Identification of a New Functional Domain in Angiopoietin-like 3 (ANGPTL3) and Angiopoietin-like 4 (ANGPTL4) Involved in Binding and Inhibition of Lipoprotein Lipase (LPL)

    المؤلفون: E-Chiang Lee, Urvi Desai, Gennady Gololobov, Seokjoo Hong, Xiao Feng, Xuan-Chuan Yu, Jason Gay, Nat Wilganowski, Cuihua Gao, Ling-Ling Du, Joan Chen, Yi Hu, Sharon Zhao, Laura Kirkpatrick, Matthias Schneider, Brian P. Zambrowicz, Greg Landes, David R. Powell, William K. Sonnenburg

    المصدر: Journal of Biological Chemistry. 284:13735-13745

    مصطلحات موضوعية: medicine.drug_class, Hyperlipidemias, Lipids and Lipoproteins: Metabolism, Regulation, and Signaling, Monoclonal antibody, Biochemistry, Epitope, Angiopoietin, Mice, ANGPTL4, ANGPTL3, medicine, Angiopoietin-Like Protein 4, Animals, Humans, Molecular Biology, Triglycerides, Angiopoietin-Like Protein 3, Mice, Knockout, chemistry.chemical_classification, Lipoprotein lipase, biology, Antibodies, Monoclonal, Cell Biology, Molecular biology, Protein Structure, Tertiary, Amino acid, Lipoprotein Lipase, Angiopoietin-like Proteins, chemistry, biology.protein, Antibody, Angiopoietins, Protein Binding

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c958a4920ab13b50f063c680ef2086aTest
    https://doi.org/10.1074/jbc.m807899200Test


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  5. 5
    Identification of a New Variant of PDE1A Calmodulin-Stimulated Cyclic Nucleotide Phosphodiesterase Expressed in Mouse Sperm1

    المؤلفون: William K. Sonnenburg, Scott H. Soderling, Joseph A. Beavo, Chen Yan, Masami Shimizu-Albergine, Valeria Vasta

    المصدر: Biology of Reproduction. 73:598-609

    مصطلحات موضوعية: Cyclic nucleotide phosphodiesterase, Alternative splicing, Acrosome reaction, Cell Biology, General Medicine, Biology, Open reading frame, Cyclic nucleotide, chemistry.chemical_compound, Reproductive Medicine, chemistry, Biochemistry, Complementary DNA, Second messenger system, Gene

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::66ad37172a5621d9ca368fc40824ba2fTest
    https://doi.org/10.1095/biolreprod.104.039180Test


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  6. 6
    Stage and Cell-Specific Expression of Calmodulin-Dependent Phosphodiesterases in Mouse Testis1

    المؤلفون: Joseph A. Beavo, William K. Sonnenburg, Allan Z. Zhao, Chen Yan

    المصدر: Biology of Reproduction. 64:1746-1754

    مصطلحات موضوعية: endocrine system, medicine.medical_specialty, Spermatid, urogenital system, Immunocytochemistry, Phosphodiesterase, Cell Biology, General Medicine, In situ hybridization, Biology, Cell biology, Cyclic nucleotide, chemistry.chemical_compound, medicine.anatomical_structure, Prophase, Endocrinology, Reproductive Medicine, chemistry, Internal medicine, Gene expression, Second messenger system, medicine

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::bf9acd07214a1ad73224f83655332048Test
    https://doi.org/10.1095/biolreprod64.6.1746Test


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  7. 7
    دورية أكاديمية
    Identification of a New Variant of PDE1A Calmodulin-Stimulated Cyclic Nucleotide Phosphodiesterase Expressed in Mouse Sperm1

    المؤلفون: Valeria Vasta, William K. Sonnenburg, Chen Yan, Scott H. Soderling, Masami Shimizu-Albergine, Joseph A. Beavo

    المساهمون: Valeria Vasta, William K. Sonnenburg, Chen Yan, Scott H. Soderling, Masami Shimizu-Albergine, Joseph A. Beavo

    المصدر: https://doi.org/10.1095/biolreprod.104.039180Test.

    جغرافية الموضوع: world

    وصف الملف: text/HTML

    الإتاحة: https://doi.org/10.1095/biolreprod.104.039180Test

    View record in BASE

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  8. 8
    دورية أكاديمية
    Stage and Cell-Specific Expression of Calmodulin-Dependent Phosphodiesterases in Mouse Testis1

    المؤلفون: Chen Yan, Allan Z. Zhao, William K. Sonnenburg, Joseph A. Beavo

    المساهمون: Chen Yan, Allan Z. Zhao, William K. Sonnenburg, Joseph A. Beavo

    المصدر: https://doi.org/10.1095/biolreprod64.6.1746Test.

    جغرافية الموضوع: world

    وصف الملف: text/HTML

    الإتاحة: https://doi.org/10.1095/biolreprod64.6.1746Test

    View record in BASE

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  9. 9
    Calmodulin-stimulated cyclic nucleotide phosphodiesterase (PDE1C) is induced in human arterial smooth muscle cells of the synthetic, proliferative phenotype

    المؤلفون: Karin E. Bornfeldt, Irina G. Rybalkina, Sergei D. Rybalkin, William K. Sonnenburg, Kim Hanson, Edwin G. Krebs, Joseph A. Beavo, Keith S. Kwak

    المصدر: Journal of Clinical Investigation. 100:2611-2621

    مصطلحات موضوعية: Adult, medicine.medical_specialty, Transcription, Genetic, Calmodulin, Arteriosclerosis, Aorta, Thoracic, Muscle, Smooth, Vascular, law.invention, 3',5'-Cyclic-GMP Phosphodiesterases, law, Internal medicine, medicine.artery, medicine, Animals, Humans, Enzyme inducer, Cells, Cultured, Aorta, biology, Cyclic nucleotide phosphodiesterase, Phosphoric Diester Hydrolases, Infant, Newborn, Infant, Phosphodiesterase, Haplorhini, General Medicine, Cyclic Nucleotide Phosphodiesterases, Type 1, musculoskeletal system, medicine.disease, Phenotype, Recombinant Proteins, Rats, Cell biology, Endocrinology, 3',5'-Cyclic-AMP Phosphodiesterases, Enzyme Induction, cardiovascular system, biology.protein, Recombinant DNA, tissues, Sudden Infant Death, Research Article

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::755c49bdf150320e20aa0a8276e2f7f9Test
    https://doi.org/10.1172/jci119805Test


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  10. 10
    Isolation and characterization of human cDNAs encoding a cGMP-stimulated 3′,5′-cyclic nucleotide phosphodiesterase

    المؤلفون: Guy J Rosman, Kate Loughney, Timothy J. Martins, Joseph A. Beavo, Ken Ferguson, William K. Sonnenburg

    المصدر: Gene. 191:89-95

    مصطلحات موضوعية: DNA, Complementary, Molecular Sequence Data, Biology, Exon, 3',5'-Cyclic-GMP Phosphodiesterases, Complementary DNA, Genetics, medicine, Animals, Humans, Amino Acid Sequence, RNA, Messenger, Cyclic GMP, chemistry.chemical_classification, Base Sequence, Sequence Homology, Amino Acid, Cyclic nucleotide phosphodiesterase, cDNA library, Phosphodiesterase, General Medicine, Molecular biology, Rats, Amino acid, Enzyme Activation, Biochemistry, chemistry, Cattle, Phosphodiesterase 2, EHNA, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b41853d68c90679b2c3b8a4769cb4a77Test
    https://doi.org/10.1016/s0378-1119Test(97)00046-2


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