يعرض 1 - 10 نتائج من 54 نتيجة بحث عن '"William H. Chappell"', وقت الاستعلام: 0.85s تنقيح النتائج
  1. 1
    Influences of TP53 and the anti-aging DDR1 receptor in controlling Raf/MEK/ERK and PI3K/Akt expression and chemotherapeutic drug sensitivity in prostate cancer cell lines

    المؤلفون: Giuseppe Montalto, Linda S. Steelman, Alberto M. Martelli, Lucio Cocco, James A. McCubrey, Saverio Candido, Ferdinando Nicoletti, Massimo Libra, Melchiorre Cervello, Shaw M. Akula, Stephen L. Abrams, William H. Chappell, Stefano Ratti

    المساهمون: Chappell, William H, Candido, Saverio, Abrams, Stephen L, Akula, Shaw M, Steelman, Linda S, Martelli, Alberto M, Ratti, Stefano, Cocco, Lucio, Cervello, Melchiorre, Montalto, Giuseppe, Nicoletti, Ferdinando, Libra, Massimo, McCubrey, James A

    المصدر: Aging (Albany, N.Y. Online) 12 (2020): 10194–10210. doi:10.18632/aging.103377
    info:cnr-pdr/source/autori:Chappell WH; Candido S; Abrams SL; Akula SM; Steelman LS; Martelli AM; Ratti S; Cocco L; Cervello M; Montalto G; Nicoletti F; Libra M; McCubrey JA;/titolo:Influences of TP53 and the anti-aging DDR1 receptor in controlling Raf%2FMEK%2FERK and PI3K%2FAkt expression and chemotherapeutic drug sensitivity in prostate cancer cell lines/doi:10.18632%2Faging.103377/rivista:Aging (Albany, N.Y. Online)/anno:2020/pagina_da:10194/pagina_a:10210/intervallo_pagine:10194–10210/volume:12
    Aging (Albany NY)

    مصطلحات موضوعية: MAPK/ERK pathway, Male, collagen, Aging, RAF/MEK/ERK, MAP Kinase Signaling System, Antineoplastic Agents, discoidin domain receptor (DDR1), DDR, Collagen receptor, Phosphatidylinositol 3-Kinases, Discoidin Domain Receptor 1, Cell Line, Tumor, Humans, Rapamycin, TP53, Receptor, Protein kinase B, PI3K/AKT/mTOR pathway, DDR1, Chemistry, Wild type, Prostate, Prostatic Neoplasms, chemoresistance, Cell Biology, prostate cancer, Drug Resistance, Neoplasm, Mutation, Cancer research, raf Kinases, Tumor Suppressor Protein p53, Discoidin domain, Research Paper

    وصف الملف: STAMPA

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae1d22962758c7a132d3c12cb5324a1bTest
    https://publications.cnr.it/doc/425339Test


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  2. 2
    Therapeutic resistance in breast cancer cells can result from deregulated EGFR signaling

    المؤلفون: Lucio Cocco, James A. McCubrey, Stefano Ratti, Lucia Manzoli, Saverio Candido, Shaw M. Akula, Stephen L. Abrams, William H. Chappell, Alberto M. Martelli, Giuseppe Montalto, Linda S. Steelman, Massimo Libra, Melchiorre Cervello

    المساهمون: Steelman L.S., Chappell W.H., Akula S.M., Abrams S.L., Cocco L., Manzoli L., Ratti S., Martelli A.M., Montalto G., Cervello M., Libra M., Candido S., McCubrey J.A.

    المصدر: Advances in Biological Regulation
    78 (2020). doi:10.1016/j.jbior.2020.100758
    info:cnr-pdr/source/autori:Linda S Steelman; William H Chappell; Shaw M Akula; Stephen L Abrams; Lucio Cocco; Lucia Manzoli; Stefano Ratti; Alberto M Martelli; Giuseppe Montalto; Melchiorre Cervello; Massimo Libra; Saverio Candido; James A McCubrey;/titolo:Therapeutic resistance in breast cancer cells can result from deregulated EGFR signaling/doi:10.1016%2Fj.jbior.2020.100758/rivista:Advances in Biological Regulation (Print)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:78

    مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, EGFRvIII, Cancer Research, EGFR, Estrogen receptor, Antineoplastic Agents, Breast Neoplasms, 03 medical and health sciences, 0302 clinical medicine, Breast cancer, Cell Line, Tumor, Genetics, Humans, Medicine, PTEN, Epidermal growth factor receptor, skin and connective tissue diseases, Molecular Biology, Protein kinase B, PI3K/AKT/mTOR pathway, biology, business.industry, Cancer, medicine.disease, ErbB Receptors, 030104 developmental biology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Drug resistance, biology.protein, Cancer research, Molecular Medicine, Female, business, Signal Transduction, V-Erb-B

    وصف الملف: STAMPA

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbe510ef421b020f42d4799d6b3c383bTest
    http://hdl.handle.net/20.500.11769/488509Test


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  3. 3
    Novel roles of androgen receptor, epidermal growth factor receptor, TP53, regulatory RNAs, NF-kappa-B, chromosomal translocations, neutrophil associated gelatinase, and matrix metalloproteinase-9 in prostate cancer and prostate cancer stem cells

    المؤلفون: Agnieszka Gizak, Alberto M. Martelli, Linda S. Steelman, James A. McCubrey, David M. Terrian, Timothy L. Fitzgerald, Lucio Cocco, Dariusz Rakus, Stephen L. Abrams, William H. Chappell, Kvin Lertpiriyapong

    المساهمون: Chappell, Wh, Abrams, Sl, Lertpiriyapong, K, Fitzgerald, Tl, Martelli, AM, Cocco, L, Rakus, D, Gizak, A, Terrian, D, Steelman, LS, McCubrey, JA.

    المصدر: Advances in Biological Regulation. 60:64-87

    مصطلحات موضوعية: Male, 0301 basic medicine, PCA3, Cancer Research, miRs, Neutrophils, EGFR, Biology, medicine.disease_cause, Translocation, Genetic, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, Cancer stem cell, KRa, Genetics, medicine, Animals, Humans, Epidermal growth factor receptor, Molecular Biology, GSK-3, Tumor microenvironment, NF-kappa B, Prostatic Neoplasms, medicine.disease, Metformin, ErbB Receptors, Androgen receptor, MicroRNAs, 030104 developmental biology, Prostate cancer screening, Matrix Metalloproteinase 9, Gelatinases, Receptors, Androgen, Drug resistance, 030220 oncology & carcinogenesis, Immunology, Neoplastic Stem Cells, Cancer research, biology.protein, Molecular Medicine, KRAS, Tumor Suppressor Protein p53

    وصف الملف: STAMPA

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::205c779978d1ead40d3806d96d9a22adTest
    https://doi.org/10.1016/j.jbior.2015.10.001Test


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  4. 4
    Roles of p53, NF-κB and the androgen receptor in controlling NGAL expression in prostate cancer cell lines

    المؤلفون: Massimo Libra, Lucio Cocco, Giuseppe Montalto, Giulia Ramazzotti, Roger Ove, Melchiorre Cervello, Suzanne Russo, James A. McCubrey, Xiaohong Leng, Linda S. Steelman, Ralph B. Arlinghaus, Stephen L. Abrams, Saverio Candido, William H. Chappell, Alberto M. Martelli

    المساهمون: Chappell, William H., Candido, Saverio, Abrams, Stephen L., Russo, Suzanne, Ove, Roger, Martelli, Alberto M., Cocco, Lucio, Ramazzotti, Giulia, Cervello, Melchiorre, Montalto, Giuseppe, Steelman, Linda S., Leng, Xiaohong, Arlinghaus, Ralph B., Libra, Massimo, McCubrey, James A., W.H. Chappell, S. Candido, S.L. Abramsa, S. Russod, R. Oved, A.M. Martelli, L. Cocco, G. Ramazzotti, M. Cervello, G. Montalto, L.S. Steelman, X. Lengi, R.B. Arlinghaus, M.Libra J.A. McCubrey.

    مصطلحات موضوعية: Male, 0301 basic medicine, p53, Cancer Research, Lipocalin, MMP9, Metastasis, 03 medical and health sciences, Prostate cancer, DU145, Genetic, Cell Line, Tumor, androgen receptor, LNCaP, Genetics, medicine, Humans, NF-kappaB, NGAL, Molecular Biology, Chemistry, NF-kappa B, Prostatic Neoplasms, medicine.disease, prostate cancer, Gene Expression Regulation, Neoplastic, Androgen receptor, 030104 developmental biology, Matrix Metalloproteinase 9, Receptors, Androgen, Cell culture, Cancer research, Molecular Medicine, Tumor Suppressor Protein p53

    وصف الملف: STAMPA

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11d3a7d1b72ee2173168bca082a04fb7Test
    http://hdl.handle.net/20.500.11769/334719Test


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  5. 5
    Novel approaches to target cancer initiating cells–Eliminating the root of the cancer

    المؤلفون: James A. McCubrey, Kazuo Umezawa, Linda S. Steelman, Stephen L. Abrams, William H. Chappell, Lucio Cocco, Richard A. Franklin, Alberto M. Martelli

    المساهمون: James A. McCubrey, Stephen L. Abram, Kazuo Umezawa, Lucio Cocco, Alberto M. Martelli, Richard A. Franklin, William H. Chappell, Linda S. Steelman

    المصدر: Advances in Biological Regulation. 52:249-264

    مصطلحات موضوعية: Cancer Research, Root (linguistics), business.industry, Cancer, Antineoplastic Agents, medicine.disease, Models, Biological, cancer initiating cell, Text mining, Neoplasms, Neoplastic Stem Cells, Genetics, Cancer research, Animals, Humans, Molecular Medicine, Medicine, NF kappa B, HEDGEHOG PATHWAY (HH), business, Molecular Biology, Signal Transduction

    وصف الملف: STAMPA

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfb5121976f22a0ec6556edf031b4653Test
    https://doi.org/10.1016/j.advenzreg.2011.09.011Test


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  6. 6
    Inhibition of GSK-3β activity can result in drug and hormonal resistance and alter sensitivity to targeted therapy in MCF-7 breast cancer cells

    المؤلفون: James A. McCubrey, Nicole Marie Davis, Linda S. Steelman, Stephen L. Abrams, William H. Chappell, Kristin Stadelman, Melissa L. Sokolosky

    المصدر: Cell Cycle

    مصطلحات موضوعية: MAPK/ERK pathway, Antineoplastic Agents, Hormonal, macromolecular substances, mTORC1, Mechanistic Target of Rapamycin Complex 1, Pharmacology, Biology, Glycogen Synthase Kinase 3, Cell Cycle News & Views, Report, medicine, Humans, Doxorubicin, Molecular Targeted Therapy, Phosphorylation, skin and connective tissue diseases, Molecular Biology, Protein kinase B, PI3K/AKT/mTOR pathway, Sirolimus, Antibiotics, Antineoplastic, Glycogen Synthase Kinase 3 beta, TOR Serine-Threonine Kinases, MEK inhibitor, Cell Biology, Transfection, Tamoxifen, MCF-7, Drug Resistance, Neoplasm, Multiprotein Complexes, MCF-7 Cells, Cancer research, Female, Developmental Biology, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20480f6b63fcf1beddc4323f3cc8976fTest
    https://doi.org/10.4161/cc.27728Test


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  7. 7
    Mutations and Deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascades Which Alter Therapy Response

    المؤلفون: Giuseppe Montalto, Jörg Bäsecke, Ferdinando Nicoletti, Melchiorre Cervello, Maria Clorinda Mazzarino, James A. McCubrey, Alberto M. Martelli, Danijela Maksimović-Ivanić, Massimo Libra, Camilla Evangelisti, Saverio Candido, Paolo Fagone, Sanja Mijatović, Francesca Chiarini, Linda S. Steelman, Grazia Malaponte, Stephen L. Abrams, William H. Chappell, Agostino Tafuri, Michele Milella, Lucio Cocco

    المساهمون: J.A. McCubrey, L.S. Steelman, W.H. Chappell, S.L. Abram, G. Montalto, M. Cervello, F. Nicoletti, P. Fagone, Graziella Malaponte, M.C. Mazzarino, S. Candido, M. Libra, J. Bäsecke, S. Mijatovic, D. Maksimovic-Ivanic, M. Milella, A. Tafuri, L. Cocco, C. Evangelisti, F. Chiarini, A.M. Martelli., McCubrey, JA, Steelman, LS, Chappell, WH, Abrams, SL, Montalto, G, Cervello, M, Nicoletti, F, Fagone, P, Malaponte, G, Mazzarino, MC, Candido, S, Libra, M, Bäsecke, J, Mijatovic, S, Maksimovic-Ivanic, D, Milella, M, Tafuri, A, Cocco, L, Evangelisti, C, Chiarini, F, Martelli, AM

    المصدر: Oncotarget
    Publons
    ResearcherID

    مصطلحات موضوعية: MAPK/ERK pathway, Premature aging, MAP Kinase Signaling System, Targeted Therapy, Therapy Resistance, Mutations, Raf, Akt, PI3K, mTOR, Mtor, Reviews, Pi3k, PI3K, Receptor tyrosine kinase, Akt, Mutations, Raf, Targeted therapy, Therapy resistance, Phosphatidylinositol 3-Kinases, 03 medical and health sciences, 0302 clinical medicine, Animals, Humans, PTEN, Extracellular Signal-Regulated MAP Kinases, Protein kinase B, PI3K/AKT/mTOR pathway, 030304 developmental biology, 0303 health sciences, biology, Chemistry, TOR Serine-Threonine Kinases, PTEN Phosphohydrolase, Targeted Therapy, Therapy Resistance, Protein phosphatase 2, MAP Kinase Kinase Kinases, 3. Good health, Cell biology, Oncology, 030220 oncology & carcinogenesis, Mutation, ras Proteins, mTOR, Cancer research, biology.protein, raf Kinases, Mitogen-Activated Protein Kinases, Signal transduction, Proto-Oncogene Proteins c-akt, Signal Transduction

    وصف الملف: ELETTRONICO

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d6149104f01be9d6f2da36e0404e53bTest
    https://doi.org/10.18632/oncotarget.652Test


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  8. 8
    Homologous Recombination Repair Factors Rad51 and BRCA1 Are Necessary for Productive Replication of Human Papillomavirus 31

    المؤلفون: William H. Chappell, Daniel C. Anacker, Dipendra Gautam, Bryan A. Johnson, Cary A. Moody, Suzan T. Ok

    مصطلحات موضوعية: 0301 basic medicine, Transcription, Genetic, Papillomavirus E7 Proteins, Immunology, Eukaryotic DNA replication, Biology, Pre-replication complex, Virus Replication, Microbiology, DNA replication factor CDT1, 03 medical and health sciences, Replication factor C, Control of chromosome duplication, Virology, Humans, Human papillomavirus 31, Replication protein A, Cells, Cultured, Genetics, BRCA1 Protein, Recombinational DNA Repair, Epithelial Cells, Fibroblasts, Genome Replication and Regulation of Viral Gene Expression, Up-Regulation, 030104 developmental biology, Licensing factor, Gene Expression Regulation, Insect Science, Host-Pathogen Interactions, biology.protein, Origin recognition complex, Rad51 Recombinase

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5305eaed93a75388fe50cb3f41a2b816Test
    https://europepmc.org/articles/PMC4810724Test/


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  9. 9
    Targeting the Cancer Initiating Cell: The Ultimate Target for Cancer Therapy

    المؤلفون: Antonio Bonati, Stephen L. Abrams, William H. Chappell, Piotr Laidler, Danijela Maksimović-Ivanić, Linda S. Steelman, Francac Stivala, Giuseppeo Montalto, Sanja Mijatović, Giovanni Ligresti, Negin Misaghian, Massimo Libra, James A. McCubrey, Alberto M. Martelli, Ferdinando Nicoletti, Jörg Bäsecke, Lucio Cocco, Camilla Evangelisti, Melchiorre Cervello

    المساهمون: J. A. McCubrey, L.S. Steelman, S.L. Abram, N. Misaghian, W.H. Chappell1, J. Bäsecke, F. Nicoletti, M. Libra, G. Ligresti, F. Stivala, D. Maksimovic-Ivanic, S. Mijatovic, G. Montalto, M. Cervello, P. Laidler, A. Bonati, C. Evangelisti, L. Cocco, A.M. Martelli., McCubrey, JA, Steelman, LS, Abrams, SL, Misaghian, N, Chappell, WH, Basecke, J, Nicoletti, F, Libra, M, Ligresti, G, Stivala, F, Maksimovic-Ivanic, D, Mijatovic, S, Montalto, G, Cervello, M, Laidler, P, Bonati, A, Evangelisti, C, Cocco, L, Martelli, AM

    المصدر: Current Pharmaceutical Design. 18:1784-1795

    مصطلحات موضوعية: PTEN, germinal mutation, chemotherapeutic, medicine.medical_treatment, Antineoplastic Agents, PI3K, Targeted therapy, Metastasis, Mice, 03 medical and health sciences, TARGETED THERAPY, 0302 clinical medicine, Cancer stem cell, Neoplasms, radiological, Drug Discovery, medicine, Animals, Humans, Akt, mTOR, Therapeutic sensitivity, PI3K/AKT/mTOR pathway, 030304 developmental biology, Pharmacology, Biological Products, 0303 health sciences, biology, AKT, MTOR, CD44, Wnt signaling pathway, Cancer, targeted therapy, medicine.disease, 3. Good health, therapeutic sensitivity, xenografts, 030220 oncology & carcinogenesis, Immunology, Neoplastic Stem Cells, Cancer research, biology.protein

    وصف الملف: STAMPA

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d358d54125a8aac8294e0d5457f6c40Test
    https://doi.org/10.2174/138161212799859701Test


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  10. 10
    Cooperative Effects of Akt-1 and Raf-1 on the Induction of Cellular Senescence in Doxorubicin or Tamoxifen Treated Breast Cancer Cells

    المؤلفون: Jackson R. Taylor, Linda S. Steelman, Stephen L. Abrams, William H. Chappell, Brian D. Lehmann, James A. McCubrey

    المصدر: Oncotarget

    مصطلحات موضوعية: Senescence, MAPK/ERK pathway, Time Factors, Antineoplastic Agents, Hormonal, Drug Resistance, Breast Neoplasms, Transfection, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, medicine, Humans, PTEN, Doxorubicin, skin and connective tissue diseases, Protein kinase B, Cellular Senescence, PI3K/AKT/mTOR pathway, 030304 developmental biology, 0303 health sciences, Antibiotics, Antineoplastic, Dose-Response Relationship, Drug, biology, Akt, Research Papers, 3. Good health, Proto-Oncogene Proteins c-raf, Tamoxifen, ERK, Oncology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, mTOR, biology.protein, Cancer research, Female, Proto-Oncogene Proteins c-akt, Cell aging, Signal Transduction, medicine.drug

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19a545a2f9aba97f82251a4b389d486fTest
    https://doi.org/10.18632/oncotarget.315Test


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