دورية أكاديمية
Gibbon genome and the fast karyotype evolution of small apes
العنوان: | Gibbon genome and the fast karyotype evolution of small apes |
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المؤلفون: | Carbone L, Harris RA, Gnerre S, Veeramah KR, Lorente Galdos B, Huddleston J, Meyer TJ, Herrero J, Roos C, Aken B, Anaclerio F, Baker C, Barrell D, Batzer MA, Beal K, Blancher A, Bohrson CL, Brameier M, Campbell MS, Capozzi O, Casola C, Chiatante G, Cree A, Damert A, de Jong PJ, Dumas L, Fernandez Callejo M, Flicek P, Fuchs NV, Gut I, Gut M, Hahn MW, Hernandez Rodriguez J, Hillier LW, Hubley R, Ianc B, Izsvák Z, Jablonski NG, Johnstone LM, Karimpour Fard A, Konkel MK, Kostka D, Lazar NH, Lee SL, Lewis LR, Liu Y, Locke DP, Mallick S, Mendez FL, Muffato M, Nazareth LV, Nevonen KA, O'Bleness M, Ochis C, Odom DT, Pollard KS, Quilez J, Reich D, Schumann GG, Searle S, Sikela JM, Skollar G, Smit A, Sonmez K, ten Hallers B, Terhune E, Thomas GW, Ullmer B, Walker JA, Wall JD, Walter L, Ward MC, Wheelan SJ, Whelan CW, White S, Wilhelm LJ, Woerner AE, Yandell M, Zhu B, Hammer MF, Marques Bonet T, Eichler EE, Fulton L, Fronick C, Muzny DM, Warren WC, Worley KC, Rogers J, Wilson RK, Gibbs R.A., ARCHIDIACONO, Nicoletta, ROCCHI, Mariano, VENTURA, MARIO |
المساهمون: | Carbone, L, Harris, Ra, Gnerre, S, Veeramah, Kr, Lorente Galdos, B, Huddleston, J, Meyer, Tj, Herrero, J, Roos, C, Aken, B, Anaclerio, F, Archidiacono, Nicoletta, Baker, C, Barrell, D, Batzer, Ma, Beal, K, Blancher, A, Bohrson, Cl, Brameier, M, Campbell, M, Capozzi, O, Casola, C, Chiatante, G, Cree, A, Damert, A, de Jong, Pj, Dumas, L, Fernandez Callejo, M, Flicek, P, Fuchs, Nv, Gut, I, Gut, M, Hahn, Mw, Hernandez Rodriguez, J, Hillier, Lw, Hubley, R, Ianc, B, Izsvák, Z, Jablonski, Ng, Johnstone, Lm, Karimpour Fard, A, Konkel, Mk, Kostka, D, Lazar, Nh, Lee, Sl, Lewis, Lr, Liu, Y, Locke, Dp, Mallick, S, Mendez, Fl, Muffato, M, Nazareth, Lv, Nevonen, Ka, O'Bleness, M, Ochis, C, Odom, Dt, Pollard, K, Quilez, J, Reich, D, Rocchi, Mariano, Schumann, Gg, Searle, S, Sikela, Jm, Skollar, G, Smit, A, Sonmez, K, ten Hallers, B, Terhune, E, Thomas, Gw, Ullmer, B, Ventura, Mario, Walker, Ja, Wall, Jd, Walter, L, Ward, Mc, Wheelan, Sj, Whelan, Cw, White, S, Wilhelm, Lj, Woerner, Ae, Yandell, M, Zhu, B, Hammer, Mf, Marques Bonet, T, Eichler, Ee, Fulton, L, Fronick, C, Muzny, Dm, Warren, Wc, Worley, Kc, Rogers, J, Wilson, Rk, Gibbs, R. A. |
سنة النشر: | 2014 |
المجموعة: | Università degli Studi di Bari Aldo Moro: CINECA IRIS |
مصطلحات موضوعية: | gibbon, evolution, genomes |
الوصف: | Gibbons are small arboreal apes that display an accelerated rate of evolutionary chromosomal rearrangement and occupy akey nodeinthe primate phylogeny between OldWorldmonkeys andgreat apes.Herewepresent the assembly andanalysis of a northern white-cheeked gibbon (Nomascus leucogenys) genome. We describe the propensity for a gibbon-specific retrotransposon (LAVA) to insert into chromosome segregation genes and alter transcription by providing a premature termination site, suggesting a possible molecular mechanism for the genome plasticity of the gibbon lineage. We further show that the gibbon genera (Nomascus, Hylobates, Hoolock and Symphalangus) experienced a near-instantaneous radiation 5 million years ago, coincident with major geographical changes in southeast Asia that caused cycles of habitat compression and expansion. Finally,weidentify signatures of positive selection in genes important for forelimb development (TBX5) and connective tissues (COL1A1) that may have been involved in the adaptation of gibbons to their arboreal habitat. |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | unknown |
العلاقة: | info:eu-repo/semantics/altIdentifier/wos/WOS:000341362800043; volume:513; firstpage:195; lastpage:201; numberofpages:7; journal:NATURE; http://hdl.handle.net/11586/131200Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84907284157 |
DOI: | 10.1038/nature13679 |
الإتاحة: | https://doi.org/10.1038/nature13679Test http://hdl.handle.net/11586/131200Test |
رقم الانضمام: | edsbas.B9E68F3C |
قاعدة البيانات: | BASE |
DOI: | 10.1038/nature13679 |
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