المؤلفون: Siqueira-Neto, Jair, Wicht, Kathryn, Chibale, Kelly, Burrows, Jeremy, Fidock, David, Winzeler, Elizabeth

المصدر: Nature Reviews Drug Discovery. 22(10)

مصطلحات موضوعية: Animals, Female, Humans, Antimalarials, Plasmodium, Drug Resistance, Drug Discovery

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/21j7z4d2Test

المؤلفون: Murithi, James, Deni, Ioanna, Pasaje, Charisse, Okombo, John, Bridgford, Jessica, Gnädig, Nina, Edwards, Rachel, Yeo, Tomas, Mok, Sachel, Burkhard, Anna, Coburn-Flynn, Olivia, Istvan, Eva, Sakata-Kato, Tomoyo, Gomez-Lorenzo, Maria, Cowell, Annie, Wicht, Kathryn, Le Manach, Claire, Kalantarov, Gavreel, Dey, Sumanta, Duffey, Maëlle, Laleu, Benoît, Lukens, Amanda, Ottilie, Sabine, Vanaerschot, Manu, Trakht, Ilya, Gamo, Francisco-Javier, Wirth, Dyann, Goldberg, Daniel, Odom John, Audrey, Chibale, Kelly, Winzeler, Elizabeth, Niles, Jacquin, Fidock, David

المصدر: Cell Chemical Biology. 29(5)

مصطلحات موضوعية: ABCI3, CRISPR/Cas9, Plasmodium falciparum malaria, biphasic dose-response curves, cellular accumulation assays, conditional knockdowns, copy-number variations, heme fractionation, pfcrt, ATP-Binding Cassette Transporters, Animals, Antimalarials, Folic Acid Antagonists, Heme, Malaria, Falciparum, Membrane Transport Proteins, Parasites, Plasmodium falciparum, Protozoan Proteins, Quinolines

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/4277b0xkTest

المؤلفون: Dziwornu, Godwin Akpeko, Seanego, Donald, Fienberg, Stephen, Clements, Monica, Ferreira, Jasmin, Sypu, Venkata S., Samanta, Sauvik, Bhana, Ashlyn D., Korkor, Constance M., Garnie, Larnelle F., Teixeira, Nicole, Wicht, Kathryn J., Taylor, Dale, Olckers, Ronald, Njoroge, Mathew, Gibhard, Liezl, Salomane, Nicolaas, Wittlin, Sergio, Mahato, Rohit, Chakraborty, Arnish, Sevilleno, Nicole, Coyle, Rachael, Lee, Marcus C. S., Godoy, Luiz C., Pasaje, Charisse Flerida, Niles, Jacquin C., Reader, Janette, van der Watt, Mariette, Birkholtz, Lyn-Marié, Bolscher, Judith M., de Bruijni, Marloes H. C., Coulson, Lauren B., Basarab, Gregory S., Ghorpade, Sandeep R., Chibale, Kelly

المصدر: Journal of Medicinal Chemistry ; ISSN 0022-2623 1520-4804

الإتاحة: https://doi.org/10.1021/acs.jmedchem.4c01154Test

المؤلفون: Mambwe, Dickson, Coertzen, Dina, Leshabane, Meta, Mulubwa, Mwila, Njoroge, Mathew, Gibhard, Liezl, Girling, Gareth, Wicht, Kathryn J., Lee, Marcus C. S., Wittlin, Sergio, Moreira, Diogo Rodrigo Magalhães, Birkholtz, Lyn-Marie, Chibale, Kelly

المساهمون: Funda????o Oswaldo Cruz, Minist??rio da Ci??ncia, Tecnologia e Inova????o, University of Cape Town, National Research Foundation, South African Medical Research Council

المصدر: ACS Medicinal Chemistry Letters ; volume 15, issue 4, page 463-469 ; ISSN 1948-5875 1948-5875

مصطلحات موضوعية: Organic Chemistry, Drug Discovery, Biochemistry

الإتاحة: https://doi.org/10.1021/acsmedchemlett.3c00496Test

المؤلفون: Amod, Leah, Mohunlal, Roxanne, Teixeira, Nicole, Egan, Timothy J., Wicht, Kathryn J.

المساهمون: National Institute of Allergy and Infectious Diseases

المصدر: Scientific Reports ; volume 13, issue 1 ; ISSN 2045-2322

مصطلحات موضوعية: Multidisciplinary

الإتاحة: https://doi.org/10.1038/s41598-023-29273-wTest
https://www.nature.com/articles/s41598-023-29273-w.pdfTest
https://www.nature.com/articles/s41598-023-29273-wTest

المؤلفون: Wicht, Kathryn Jean

مرشدي الرسالة: Egan, Timothy J, Hunter, Roger

مصطلحات موضوعية: Chemistry

وصف الملف: application/pdf

الإتاحة: http://hdl.handle.net/11427/16939Test

المؤلفون: Small-Saunders, Jennifer L., Hagenah, Laura M., Wicht, Kathryn J., Dhingra, Satish K., Deni, Ioanna, Kim, Jonathan, Vendome, Jeremie, Gil-Iturbe, Eva, Roepe, Paul D., Mehta, Monica, Mancia, Filippo, Quick, Matthias, Eppstein, Margaret J., Fidock, David A.

المساهمون: Cui, Liwang, Doris Duke Charitable Foundation, National Institute of Allergy and Infectious Diseases, National Institutes of Health

المصدر: PLOS Pathogens ; volume 18, issue 2, page e1010278 ; ISSN 1553-7374

الإتاحة: https://doi.org/10.1371/journal.ppat.1010278Test

المؤلفون: Wicht, Kathryn J, Small-Saunders, Jennifer L, Hagenah, Laura M, Mok, Sachel, Fidock, David A

المساهمون: National Institute of Allergy and Infectious Diseases, National Institutes of Health, Columbia University Graduate Training Program in Microbiology and Immunology

المصدر: The Journal of Infectious Diseases ; volume 226, issue 11, page 2021-2029 ; ISSN 0022-1899 1537-6613

مصطلحات موضوعية: Infectious Diseases, Immunology and Allergy

الإتاحة: https://doi.org/10.1093/infdis/jiac365Test
https://academic.oup.com/jid/article-pdf/226/11/2021/47369625/jiac365.pdfTest

المؤلفون: Dorjsuren, Dorjbal, Eastman, Richard T., Wicht, Kathryn J., Jansen, Daniel, Talley, Daniel C., Sigmon, Benjamin A., Zakharov, Alexey V., Roncal, Norma, Girvin, Andrew T., Antonova-Koch, Yevgeniya, Will, Paul M., Shah, Pranav, Sun, Hongmao, Klumpp-Thomas, Carleen, Mok, Sachel, Yeo, Tomas, Meister, Stephan, Marugan, Juan Jose, Ross, Leila S., Xu, Xin, Maloney, David J., Jadhav, Ajit, Mott, Bryan T., Sciotti, Richard J., Winzeler, Elizabeth A., Waters, Norman C., Campbell, Robert F., Huang, Wenwei, Simeonov, Anton, Fidock, David A.

المساهمون: U.S. Department of Defense, National Institute of Allergy and Infectious Diseases, NIH

المصدر: Scientific Reports ; volume 11, issue 1 ; ISSN 2045-2322

مصطلحات موضوعية: Multidisciplinary

الإتاحة: https://doi.org/10.1038/s41598-021-81486-zTest
https://www.nature.com/articles/s41598-021-81486-z.pdfTest
https://www.nature.com/articles/s41598-021-81486-zTest

المؤلفون: Chibale, Kelly, Wicht, Kathryn J., Woodland, John G.

المصدر: Journal of Medicinal Chemistry ; volume 64, issue 15, page 10513-10516 ; ISSN 0022-2623 1520-4804

مصطلحات موضوعية: Drug Discovery, Molecular Medicine

الإتاحة: https://doi.org/10.1021/acs.jmedchem.1c01183Test