المؤلفون: Haas, Kelsey M, McGregor, Michael J, Bouhaddou, Mehdi, Polacco, Benjamin J, Kim, Eun-Young, Nguyen, Thong T, Newton, Billy W, Urbanowski, Matthew, Kim, Heejin, Williams, Michael AP, Rezelj, Veronica V, Hardy, Alexandra, Fossati, Andrea, Stevenson, Erica J, Sukerman, Ellie, Kim, Tiffany, Penugonda, Sudhir, Moreno, Elena, Braberg, Hannes, Zhou, Yuan, Metreveli, Giorgi, Harjai, Bhavya, Tummino, Tia A, Melnyk, James E, Soucheray, Margaret, Batra, Jyoti, Pache, Lars, Martin-Sancho, Laura, Carlson-Stevermer, Jared, Jureka, Alexander S, Basler, Christopher F, Shokat, Kevan M, Shoichet, Brian K, Shriver, Leah P, Johnson, Jeffrey R, Shaw, Megan L, Chanda, Sumit K, Roden, Dan M, Carter, Tonia C, Kottyan, Leah C, Chisholm, Rex L, Pacheco, Jennifer A, Smith, Maureen E, Schrodi, Steven J, Albrecht, Randy A, Vignuzzi, Marco, Zuliani-Alvarez, Lorena, Swaney, Danielle L, Eckhardt, Manon, Wolinsky, Steven M, White, Kris M, Hultquist, Judd F, Kaake, Robyn M, García-Sastre, Adolfo, Krogan, Nevan J

المصدر: Nature Communications. 14(1)

مصطلحات موضوعية: Microbiology, Medical Microbiology, Biomedical and Clinical Sciences, Biological Sciences, Infectious Diseases, Prevention, Emerging Infectious Diseases, Vaccine Related, Influenza, Pneumonia & Influenza, Biodefense, Biotechnology, 2.1 Biological and endogenous factors, 2.2 Factors relating to the physical environment, Aetiology, Infection, Humans, Influenza A virus, Influenza, Human, Influenza A Virus, H5N1 Subtype, Influenza A Virus, H3N2 Subtype, Proteomics, Virus Replication, COVID-19, SARS-CoV-2, Antiviral Agents, Host-Pathogen Interactions

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/5h41d3svTest

المؤلفون: Varona, Jose F, Landete, Pedro, Lopez-Martin, Jose A, Estrada, Vicente, Paredes, Roger, Guisado-Vasco, Pablo, de Orueta, Lucia Fernandez, Torralba, Miguel, Fortun, Jesus, Vates, Roberto, Barberan, Jose, Clotet, Bonaventura, Ancochea, Julio, Carnevali, Daniel, Cabello, Noemi, Porras, Lourdes, Gijon, Paloma, Monereo, Alfonso, Abad, Daniel, Zuñiga, Sonia, Sola, Isabel, Rodon, Jordi, Vergara-Alert, Julia, Izquierdo-Useros, Nuria, Fudio, Salvador, Pontes, Maria Jose, de Rivas, Beatriz, de Velasco, Patricia Giron, Nieto, Antonio, Gomez, Javier, Aviles, Pablo, Lubomirov, Rubin, Belgrano, Alvaro, Sopesen, Belen, White, Kris M, Rosales, Romel, Yildiz, Soner, Reuschl, Ann-Kathrin, Thorne, Lucy G, Jolly, Clare, Towers, Greg J, Zuliani-Alvarez, Lorena, Bouhaddou, Mehdi, Obernier, Kirsten, McGovern, Briana L, Rodriguez, M Luis, Enjuanes, Luis, Fernandez-Sousa, Jose M, Krogan, Nevan J, Jimeno, Jose M, Garcia-Sastre, Adolfo

المصدر: Life Science Alliance. 5(4)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Clinical Research, Infectious Diseases, Cancer, Lung, Clinical Trials and Supportive Activities, Patient Safety, Prevention, Evaluation of treatments and therapeutic interventions, 6.1 Pharmaceuticals, Good Health and Well Being, Adult, Aged, COVID-19, Cell Line, Tumor, Depsipeptides, Drug Evaluation, Preclinical, Female, Hospitalization, Humans, Kaplan-Meier Estimate, Length of Stay, Male, Middle Aged, Neutropenia, Peptides, Cyclic, SARS-CoV-2, Treatment Outcome, Viral Load, COVID-19 Drug Treatment, Biological sciences, Biomedical and clinical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/5pg2r03wTest

المؤلفون: Tummino, Tia A, Rezelj, Veronica V, Fischer, Benoit, Fischer, Audrey, O'Meara, Matthew J, Monel, Blandine, Vallet, Thomas, White, Kris M, Zhang, Ziyang, Alon, Assaf, Schadt, Heiko, O'Donnell, Henry R, Lyu, Jiankun, Rosales, Romel, McGovern, Briana L, Rathnasinghe, Raveen, Jangra, Sonia, Schotsaert, Michael, Galarneau, Jean-René, Krogan, Nevan J, Urban, Laszlo, Shokat, Kevan M, Kruse, Andrew C, García-Sastre, Adolfo, Schwartz, Olivier, Moretti, Francesca, Vignuzzi, Marco, Pognan, Francois, Shoichet, Brian K

المصدر: Science. 373(6554)

مصطلحات موضوعية: Lung, Infectious Diseases, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Good Health and Well Being, A549 Cells, Animals, Antiviral Agents, COVID-19, Cations, Chlorocebus aethiops, Dose-Response Relationship, Drug, Drug Repositioning, Female, Humans, Lipidoses, Mice, Microbial Sensitivity Tests, Phospholipids, SARS-CoV-2, Surface-Active Agents, Vero Cells, Virus Replication, COVID-19 Drug Treatment, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/41h684bvTest

المؤلفون: Le, Brian L, Andreoletti, Gaia, Oskotsky, Tomiko, Vallejo-Gracia, Albert, Rosales, Romel, Yu, Katharine, Kosti, Idit, Leon, Kristoffer E, Bunis, Daniel G, Li, Christine, Kumar, G Renuka, White, Kris M, García-Sastre, Adolfo, Ott, Melanie, Sirota, Marina

المصدر: Scientific reports. 11(1)

مصطلحات موضوعية: Humans, Antiviral Agents, Computational Biology, Drug Repositioning, Transcriptome, COVID-19, SARS-CoV-2, Vaccine Related, Infectious Diseases, Biodefense, Pneumonia, Emerging Infectious Diseases, Lung, Prevention, 5.1 Pharmaceuticals, Infection

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/44s17770Test

المؤلفون: White, Kris M, Rosales, Romel, Yildiz, Soner, Kehrer, Thomas, Miorin, Lisa, Moreno, Elena, Jangra, Sonia, Uccellini, Melissa B, Rathnasinghe, Raveen, Coughlan, Lynda, Martinez-Romero, Carles, Batra, Jyoti, Rojc, Ajda, Bouhaddou, Mehdi, Fabius, Jacqueline M, Obernier, Kirsten, Dejosez, Marion, Guillén, María José, Losada, Alejandro, Avilés, Pablo, Schotsaert, Michael, Zwaka, Thomas, Vignuzzi, Marco, Shokat, Kevan M, Krogan, Nevan J, García-Sastre, Adolfo

المصدر: Science. 371(6532)

مصطلحات موضوعية: Infectious Diseases, Pneumonia & Influenza, Biotechnology, Vaccine Related, Biodefense, Lung, Orphan Drug, Emerging Infectious Diseases, Rare Diseases, Pneumonia, Prevention, 5.1 Pharmaceuticals, 5.2 Cellular and gene therapies, Development of treatments and therapeutic interventions, Infection, Good Health and Well Being, Adenosine Monophosphate, Alanine, Animals, Antiviral Agents, COVID-19, Coronavirus Nucleocapsid Proteins, Depsipeptides, Drug Evaluation, Preclinical, Female, HEK293 Cells, Humans, Mice, Inbred C57BL, Mutation, Peptide Elongation Factor 1, Peptides, Cyclic, Phosphoproteins, RNA, Viral, SARS-CoV-2, Virus Replication, COVID-19 Drug Treatment, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/7nx3v3h2Test

المؤلفون: Schoof, Michael, Faust, Bryan, Saunders, Reuben A, Sangwan, Smriti, Rezelj, Veronica, Hoppe, Nick, Boone, Morgane, Billesbølle, Christian B, Puchades, Cristina, Azumaya, Caleigh M, Kratochvil, Huong T, Zimanyi, Marcell, Deshpande, Ishan, Liang, Jiahao, Dickinson, Sasha, Nguyen, Henry C, Chio, Cynthia M, Merz, Gregory E, Thompson, Michael C, Diwanji, Devan, Schaefer, Kaitlin, Anand, Aditya A, Dobzinski, Niv, Zha, Beth Shoshana, Simoneau, Camille R, Leon, Kristoffer, White, Kris M, Chio, Un Seng, Gupta, Meghna, Jin, Mingliang, Li, Fei, Liu, Yanxin, Zhang, Kaihua, Bulkley, David, Sun, Ming, Smith, Amber M, Rizo, Alexandrea N, Moss, Frank, Brilot, Axel F, Pourmal, Sergei, Trenker, Raphael, Pospiech, Thomas, Gupta, Sayan, Barsi-Rhyne, Benjamin, Belyy, Vladislav, Barile-Hill, Andrew W, Nock, Silke, Liu, Yuwei, Krogan, Nevan J, Ralston, Corie Y, Swaney, Danielle L, García-Sastre, Adolfo, Ott, Melanie, Vignuzzi, Marco, Walter, Peter, Manglik, Aashish, Braxton, Julian R, Lopez, Kyle E, Melo, Arthur, Paulino, Joana, Pospiech, Thomas H, Thomas, Paul V, Wang, Feng, Yu, Zanlin, Dickinson, Miles Sasha, Asarnow, Daniel, Campbell, Melody G, Li, Junrui, Tsui, Tsz Kin Martin, Trinidad, Donovan, Tse, Eric, Zhou, Fengbo, Herrera, Nadia, Schulze-Gahmen, Ursula

المصدر: Science. 370(6523)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Lung, Vaccine Related, Prevention, Infectious Diseases, Pneumonia, Pneumonia & Influenza, Biodefense, Emerging Infectious Diseases, Angiotensin-Converting Enzyme 2, Animals, Antibodies, Neutralizing, Antibodies, Viral, Antibody Affinity, Chlorocebus aethiops, Cryoelectron Microscopy, Humans, Neutralization Tests, Protein Binding, Protein Stability, Single-Domain Antibodies, Spike Glycoprotein, Coronavirus, Vero Cells, QCRG Structural Biology Consortium, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/1ks1d323Test
https://escholarship.org/content/qt1ks1d323/qt1ks1d323.pdfTest

المؤلفون: Miorin, Lisa, Kehrer, Thomas, Sanchez-Aparicio, Maria Teresa, Zhang, Ke, Cohen, Phillip, Patel, Roosheel S, Cupic, Anastasija, Makio, Tadashi, Mei, Menghan, Moreno, Elena, Danziger, Oded, White, Kris M, Rathnasinghe, Raveen, Uccellini, Melissa, Gao, Shengyan, Aydillo, Teresa, Mena, Ignacio, Yin, Xin, Martin-Sancho, Laura, Krogan, Nevan J, Chanda, Sumit K, Schotsaert, Michael, Wozniak, Richard W, Ren, Yi, Rosenberg, Brad R, Fontoura, Beatriz MA, García-Sastre, Adolfo

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 117(45)

مصطلحات موضوعية: Biodefense, Emerging Infectious Diseases, Vaccine Related, Infectious Diseases, Pneumonia, Prevention, Lung, Aetiology, 2.1 Biological and endogenous factors, Infection, Good Health and Well Being, Active Transport, Cell Nucleus, Animals, Binding Sites, COVID-19, Chlorocebus aethiops, HEK293 Cells, Humans, Interferons, Nuclear Matrix-Associated Proteins, Nuclear Pore, Nuclear Pore Complex Proteins, Nucleocytoplasmic Transport Proteins, Protein Binding, STAT1 Transcription Factor, STAT2 Transcription Factor, Signal Transduction, Vero Cells, Viral Proteins, Immunization, Pneumonia & Influenza, Biotechnology, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, SARS-CoV-2, interferon signaling antagonism, STATs, ORF6, Nup98

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/00c2z9b4Test

المؤلفون: Riva, Laura, Yuan, Shuofeng, Yin, Xin, Martin-Sancho, Laura, Matsunaga, Naoko, Pache, Lars, Burgstaller-Muehlbacher, Sebastian, De Jesus, Paul D, Teriete, Peter, Hull, Mitchell V, Chang, Max W, Chan, Jasper Fuk-Woo, Cao, Jianli, Poon, Vincent Kwok-Man, Herbert, Kristina M, Cheng, Kuoyuan, Nguyen, Tu-Trinh H, Rubanov, Andrey, Pu, Yuan, Nguyen, Courtney, Choi, Angela, Rathnasinghe, Raveen, Schotsaert, Michael, Miorin, Lisa, Dejosez, Marion, Zwaka, Thomas P, Sit, Ko-Yung, Martinez-Sobrido, Luis, Liu, Wen-Chun, White, Kris M, Chapman, Mackenzie E, Lendy, Emma K, Glynne, Richard J, Albrecht, Randy, Ruppin, Eytan, Mesecar, Andrew D, Johnson, Jeffrey R, Benner, Christopher, Sun, Ren, Schultz, Peter G, Su, Andrew I, García-Sastre, Adolfo, Chatterjee, Arnab K, Yuen, Kwok-Yung, Chanda, Sumit K

المصدر: Nature. 586(7827)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Emerging Infectious Diseases, Rare Diseases, Lung, Orphan Drug, Biodefense, Infectious Diseases, Vaccine Related, Pneumonia & Influenza, Pneumonia, Prevention, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, 6.1 Pharmaceuticals, Evaluation of treatments and therapeutic interventions, Infection, Good Health and Well Being, Adenosine Monophosphate, Alanine, Alveolar Epithelial Cells, Antiviral Agents, Betacoronavirus, COVID-19, Cell Line, Coronavirus Infections, Cysteine Proteinase Inhibitors, Dose-Response Relationship, Drug, Drug Evaluation, Preclinical, Drug Repositioning, Drug Synergism, Gene Expression Regulation, Humans, Hydrazones, Induced Pluripotent Stem Cells, Models, Biological, Morpholines, Pandemics, Pneumonia, Viral, Pyrimidines, Reproducibility of Results, SARS-CoV-2, Small Molecule Libraries, Triazines, Virus Internalization, Virus Replication, COVID-19 Drug Treatment, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/6p88f41fTest

المؤلفون: Bouhaddou, Mehdi, Memon, Danish, Meyer, Bjoern, White, Kris M, Rezelj, Veronica V, Correa Marrero, Miguel, Polacco, Benjamin J, Melnyk, James E, Ulferts, Svenja, Kaake, Robyn M, Batra, Jyoti, Richards, Alicia L, Stevenson, Erica, Gordon, David E, Rojc, Ajda, Obernier, Kirsten, Fabius, Jacqueline M, Soucheray, Margaret, Miorin, Lisa, Moreno, Elena, Koh, Cassandra, Tran, Quang Dinh, Hardy, Alexandra, Robinot, Rémy, Vallet, Thomas, Nilsson-Payant, Benjamin E, Hernandez-Armenta, Claudia, Dunham, Alistair, Weigang, Sebastian, Knerr, Julian, Modak, Maya, Quintero, Diego, Zhou, Yuan, Dugourd, Aurelien, Valdeolivas, Alberto, Patil, Trupti, Li, Qiongyu, Hüttenhain, Ruth, Cakir, Merve, Muralidharan, Monita, Kim, Minkyu, Jang, Gwendolyn, Tutuncuoglu, Beril, Hiatt, Joseph, Guo, Jeffrey Z, Xu, Jiewei, Bouhaddou, Sophia, Mathy, Christopher JP, Gaulton, Anna, Manners, Emma J, Félix, Eloy, Shi, Ying, Goff, Marisa, Lim, Jean K, McBride, Timothy, O'Neal, Michael C, Cai, Yiming, Chang, Jason CJ, Broadhurst, David J, Klippsten, Saker, De Wit, Emmie, Leach, Andrew R, Kortemme, Tanja, Shoichet, Brian, Ott, Melanie, Saez-Rodriguez, Julio, tenOever, Benjamin R, Mullins, R Dyche, Fischer, Elizabeth R, Kochs, Georg, Grosse, Robert, García-Sastre, Adolfo, Vignuzzi, Marco, Johnson, Jeffery R, Shokat, Kevan M, Swaney, Danielle L, Beltrao, Pedro, Krogan, Nevan J

المصدر: Cell. 182(3)

مصطلحات موضوعية: Caco-2 Cells, Vero Cells, Animals, Humans, Pneumonia, Viral, Coronavirus Infections, Peptidyl-Dipeptidase A, Casein Kinase II, Cyclin-Dependent Kinases, p38 Mitogen-Activated Protein Kinases, Receptor Protein-Tyrosine Kinases, Proto-Oncogene Proteins, Protein Kinase Inhibitors, Antiviral Agents, Drug Evaluation, Preclinical, Proteomics, Phosphorylation, Host-Pathogen Interactions, Phosphatidylinositol 3-Kinases, HEK293 Cells, Pandemics, Spike Glycoprotein, Coronavirus, A549 Cells, Betacoronavirus, Phosphoinositide-3 Kinase Inhibitors, Chlorocebus aethiops, COVID-19, Angiotensin-Converting Enzyme 2, SARS-CoV-2, AXL, CDK, MAPK, PIKFYVE, antiviral, casein kinase II, mass spectrometry, p38, phosphoproteomics, Infectious Diseases, Prevention, Biodefense, Emerging Infectious Diseases, Vaccine Related, Lung, Infection, Developmental Biology, Biological Sciences, Medical and Health Sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/4431p9mqTest

المؤلفون: Gordon, David E, Jang, Gwendolyn M, Bouhaddou, Mehdi, Xu, Jiewei, Obernier, Kirsten, White, Kris M, O’Meara, Matthew J, Rezelj, Veronica V, Guo, Jeffrey Z, Swaney, Danielle L, Tummino, Tia A, Hüttenhain, Ruth, Kaake, Robyn M, Richards, Alicia L, Tutuncuoglu, Beril, Foussard, Helene, Batra, Jyoti, Haas, Kelsey, Modak, Maya, Kim, Minkyu, Haas, Paige, Polacco, Benjamin J, Braberg, Hannes, Fabius, Jacqueline M, Eckhardt, Manon, Soucheray, Margaret, Bennett, Melanie J, Cakir, Merve, McGregor, Michael J, Li, Qiongyu, Meyer, Bjoern, Roesch, Ferdinand, Vallet, Thomas, Mac Kain, Alice, Miorin, Lisa, Moreno, Elena, Naing, Zun Zar Chi, Zhou, Yuan, Peng, Shiming, Shi, Ying, Zhang, Ziyang, Shen, Wenqi, Kirby, Ilsa T, Melnyk, James E, Chorba, John S, Lou, Kevin, Dai, Shizhong A, Barrio-Hernandez, Inigo, Memon, Danish, Hernandez-Armenta, Claudia, Lyu, Jiankun, Mathy, Christopher JP, Perica, Tina, Pilla, Kala Bharath, Ganesan, Sai J, Saltzberg, Daniel J, Rakesh, Ramachandran, Liu, Xi, Rosenthal, Sara B, Calviello, Lorenzo, Venkataramanan, Srivats, Liboy-Lugo, Jose, Lin, Yizhu, Huang, Xi-Ping, Liu, YongFeng, Wankowicz, Stephanie A, Bohn, Markus, Safari, Maliheh, Ugur, Fatima S, Koh, Cassandra, Savar, Nastaran Sadat, Tran, Quang Dinh, Shengjuler, Djoshkun, Fletcher, Sabrina J, O’Neal, Michael C, Cai, Yiming, Chang, Jason CJ, Broadhurst, David J, Klippsten, Saker, Sharp, Phillip P, Wenzell, Nicole A, Kuzuoglu-Ozturk, Duygu, Wang, Hao-Yuan, Trenker, Raphael, Young, Janet M, Cavero, Devin A, Hiatt, Joseph, Roth, Theodore L, Rathore, Ujjwal, Subramanian, Advait, Noack, Julia, Hubert, Mathieu, Stroud, Robert M, Frankel, Alan D, Rosenberg, Oren S, Verba, Kliment A, Agard, David A, Ott, Melanie, Emerman, Michael, Jura, Natalia

المصدر: Nature. 583(7816)

مصطلحات موضوعية: Biological Sciences, Bioinformatics and Computational Biology, Biomedical and Clinical Sciences, Coronaviruses, Emerging Infectious Diseases, Infectious Diseases, Coronaviruses Therapeutics and Interventions, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Infection, Good Health and Well Being, Animals, Antiviral Agents, Betacoronavirus, COVID-19, Chlorocebus aethiops, Cloning, Molecular, Coronavirus Infections, Drug Evaluation, Preclinical, Drug Repositioning, HEK293 Cells, Host-Pathogen Interactions, Humans, Immunity, Innate, Mass Spectrometry, Molecular Targeted Therapy, Pandemics, Pneumonia, Viral, Protein Binding, Protein Biosynthesis, Protein Domains, Protein Interaction Mapping, Protein Interaction Maps, Receptors, sigma, SARS-CoV-2, SKP Cullin F-Box Protein Ligases, Vero Cells, Viral Proteins, COVID-19 Drug Treatment, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/2gt3q50xTest
https://escholarship.org/content/qt2gt3q50x/qt2gt3q50x.pdfTest