المؤلفون: Jurisic, Anamarija, Sung, Pei-Ju, Wappett, Mark, Daubriac, Julien, Lobb, Ian T, Kung, Wei-Wei, Crawford, Nyree, Page, Natalie, Cassidy, Eamon, Feutren-Burton, Stephanie, Rountree, J S Shane, Helm, Matthew D, O'Dowd, Colin R, Kennedy, Richard D, Gavory, Gerald, Cranston, Aaron N, Longley, Daniel B, Jacq, Xavier, Harrison, Timothy

المصدر: Jurisic , A , Sung , P-J , Wappett , M , Daubriac , J , Lobb , I T , Kung , W-W , Crawford , N , Page , N , Cassidy , E , Feutren-Burton , S , Rountree , J S S , Helm , M D , O'Dowd , C R , Kennedy , R D , Gavory , G , Cranston , A N , Longley , D B , Jacq , X & Harrison , T 2024 , ' USP7 inhibitors suppress tumour neoangiogenesis and promote synergy with immune checkpoint inhibitors by ....

مصطلحات موضوعية: Humans, Vascular Endothelial Growth Factor A, Immune Checkpoint Inhibitors/pharmacology, Ubiquitin-Specific Peptidase 7, Neoplasms, Neovascularization, Pathologic/drug therapy, Fibroblasts/metabolism, Tumor Microenvironment, CCAAT-Enhancer-Binding Proteins/pharmacology, Ubiquitin-Protein Ligases/pharmacology, /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

وصف الملف: application/pdf

العلاقة: https://pure.qub.ac.uk/en/publications/5fa479d6-0aa5-4450-8240-97d4b9bc1e29Test

الإتاحة: https://doi.org/10.1002/ctm2.1648Test
https://pure.qub.ac.uk/en/publications/5fa479d6-0aa5-4450-8240-97d4b9bc1e29Test
https://pureadmin.qub.ac.uk/ws/files/584466100/Downblast.pdfTest

المؤلفون: Sessler, Tamas, Quinn, Gerard P., Wappett, Mark, Rogan, Emily, Sharkey, David, Ahmaderaghi, Baharak, Lawler, Mark, Longley, Daniel B., McDade, Simon S.

المصدر: Sessler , T , Quinn , G P , Wappett , M , Rogan , E , Sharkey , D , Ahmaderaghi , B , Lawler , M , Longley , D B & McDade , S S 2023 , ' surviveR: a flexible shiny application for patient survival analysis ' , Scientific Reports , vol. 13 , 22093 . https://doi.org/10.1038/s41598-023-48894-9Test

مصطلحات موضوعية: /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

وصف الملف: application/pdf

العلاقة: https://pure.qub.ac.uk/en/publications/5ff60f6e-53c4-4d9b-adb8-bd18ad2e4520Test

الإتاحة: https://doi.org/10.1038/s41598-023-48894-9Test
https://pure.qub.ac.uk/en/publications/5ff60f6e-53c4-4d9b-adb8-bd18ad2e4520Test
https://pureadmin.qub.ac.uk/ws/files/549707748/surviveR.pdfTest

المؤلفون: Lees, Andrea, McIntyre, Alexander J., Crawford, Nyree T., Falcone, Fiammetta, McCann, Christopher, Holohan, Caitriona, Quinn, Gerard P., Roberts, Jamie Z., Sessler, Tamas, Gallagher, Peter F., Gregg, Gemma M. A., McAllister, Katherine, McLaughlin, Kirsty M., Allen, Wendy L., Egan, Laurence J., Ryan, Aideen E., Labonte-Wilson, Melissa J., Dunne, Philip D., Wappett, Mark, Coyle, Vicky M., Johnston, Patrick G., Kerr, Emma M., Longley, Daniel B., McDade, Simon S.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2020 Jul . 117(30), 17808-17819.

الوصول الحر: https://www.jstor.org/stable/26935509Test

المؤلفون: Page, Natalie, Wappett, Mark, O'Dowd, Colin R., O'Rourke, Martin, Gavory, Gerald, Zhang, Lixin, Rountree, J. S. Shane, Jordan, Linda, Barker, Oliver, Gibson, Hayley, Boyd, Caroline, Feutren-Burton, Stephanie, McLean, Estelle, Trevitt, Graham, Harrison, Timothy

المصدر: Page , N , Wappett , M , O'Dowd , C R , O'Rourke , M , Gavory , G , Zhang , L , Rountree , J S S , Jordan , L , Barker , O , Gibson , H , Boyd , C , Feutren-Burton , S , McLean , E , Trevitt , G & Harrison , T 2022 , ' Identification and development of a subtype-selective allosteric AKT inhibitor suitable for clinical development ' , Scientific Reports , vol. 12 , 15715 . https://doi.org/10.1038/s41598-022-20208-5Test

مصطلحات موضوعية: Tamoxifen, Angiogenesis Inhibitors, Serine, Phosphatidylinositol 3-Kinases - metabolism, Isoenzymes, Proto-Oncogene Proteins c-akt - metabolism, Threonine, Protein Kinase Inhibitors - pharmacology - therapeutic use, Humans

وصف الملف: application/pdf

العلاقة: https://pure.qub.ac.uk/en/publications/149e3246-450d-4699-80a2-2dd83dead1c9Test

الإتاحة: https://doi.org/10.1038/s41598-022-20208-5Test
https://pure.qub.ac.uk/en/publications/149e3246-450d-4699-80a2-2dd83dead1c9Test
https://pureadmin.qub.ac.uk/ws/files/379179592/Identification_and_development_of_a_subtype_selective_allosteric_AKT_inhibitor_suitable_for_clinical_development.pdfTest

المؤلفون: Grinkevich, Vera, Wappett, Mark, Crawford, Nyree, Price, Stacey, Lees, Andrea, McCann, Christopher, McAllister, Katherine A, Prehn, Jochen Hm, Young, Jamie, Bateson, Jessica H, Gallagher, Lewis, Michaut, Magali, Iyer, Vivek, Chatzipli, Aikaterini, Barthorpe, Syd, Ciznadija, Daniel, Sloma, Ido, Wesa, Amy, Tice, David A, Wessels, Lodewyk F A, Garnet, Matthew, Longley, Daniel B, McDermott, Ultan, McDade, Simon S

المصدر: Grinkevich , V , Wappett , M , Crawford , N , Price , S , Lees , A , McCann , C , McAllister , K A , Prehn , J H , Young , J , Bateson , J H , Gallagher , L , Michaut , M , Iyer , V , Chatzipli , A , Barthorpe , S , Ciznadija , D , Sloma , I , Wesa , A , Tice , D A , Wessels , L F A , Garnet , M , Longley , D B , McDermott , U & ....

مصطلحات موضوعية: Cancer Research, Oncology

وصف الملف: application/pdf

العلاقة: https://pure.qub.ac.uk/en/publications/4df295a5-16c9-4ce8-a0e9-7a36599869ddTest

الإتاحة: https://doi.org/10.1158/1535-7163.MCT-21-0532Test
https://pure.qub.ac.uk/en/publications/4df295a5-16c9-4ce8-a0e9-7a36599869ddTest
https://pureadmin.qub.ac.uk/ws/files/305415865/594.pdfTest

المؤلفون: Quinn, Gerard P., Sessler, Tamas, Ahmaderaghi, Baharak, Lambe, Shauna, VanSteenhouse, Harper, Lawler, Mark, Wappett, Mark, Seligmann, Bruce, Longley, Daniel B., McDade, Simon S.

المصدر: Quinn , G P , Sessler , T , Ahmaderaghi , B , Lambe , S , VanSteenhouse , H , Lawler , M , Wappett , M , Seligmann , B , Longley , D B & McDade , S S 2022 , ' classifieR a flexible interactive cloud-application for functional annotation of cancer transcriptomes ' , BMC Bioinformatics , vol. 23 , 114 . https://doi.org/10.1186/s12859-022-04641-xTest

مصطلحات موضوعية: Breast Neoplasms/genetics, Computational Biology/methods, Female, Gene Expression Profiling/methods, Humans, Software, Transcriptome, /dk/atira/pure/subjectarea/asjc/1300/1315, Structural Biology, /dk/atira/pure/subjectarea/asjc/1300/1303, Biochemistry, /dk/atira/pure/subjectarea/asjc/1300/1312, Molecular Biology, /dk/atira/pure/subjectarea/asjc/1700/1706, Computer Science Applications, /dk/atira/pure/subjectarea/asjc/2600/2604, Applied Mathematics, /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, SDG 3 - Good Health and Well-being

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1186/s12859-022-04641-xTest
https://pure.qub.ac.uk/en/publications/3aca1733-7e40-4b75-9422-a771b9bc12e9Test
https://pureadmin.qub.ac.uk/ws/files/307548570/s12859_022_04641_x.pdfTest

المؤلفون: Obasanmi, Gideon, Nesbit, M. Andrew, Cobice, Diego, Mackay, Logan, McGimpsey, Stuart, Wappett, Mark, Cranston, Aaron N., Moore, Tara C.B.

المساهمون: Almac Discovery Ltd

المصدر: Ophthalmology Science ; volume 2, issue 2, page 100150 ; ISSN 2666-9145

مصطلحات موضوعية: General Medicine

الإتاحة: https://doi.org/10.1016/j.xops.2022.100150Test
https://api.elsevier.com/content/article/PII:S2666914522000392?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2666914522000392?httpAccept=text/plainTest

المؤلفون: Wappett, Mark, Harris, Adam, Lubbock, Alexander L. R., Lobb, Ian, McDade, Simon, Overton, Ian M.

المصدر: Wappett , M , Harris , A , Lubbock , A L R , Lobb , I , McDade , S & Overton , IM 2021 , ' SynLeGG: analysis and visualization of multiomics data for discovery of cancer ‘Achilles Heels’ and gene function relationships ' , Nucleic Acids Research , vol. 49 , no. W1 , pp. W613-W618 . https://doi.org/10.1093/nar/gkab338Test

مصطلحات موضوعية: Genetics, /dk/atira/pure/subjectarea/asjc/1300/1311, name=Genetics, /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

وصف الملف: application/pdf

العلاقة: https://pure.qub.ac.uk/en/publications/c499bc1a-2c62-4d04-83f6-b69dfb1eca49Test

الإتاحة: https://doi.org/10.1093/nar/gkab338Test
https://pure.qub.ac.uk/en/publications/c499bc1a-2c62-4d04-83f6-b69dfb1eca49Test
https://pureadmin.qub.ac.uk/ws/files/240118179/syn.pdfTest

المؤلفون: Ferris, Jennifer, Espona-Fiedler, Margarita, Hamilton, Claudia, Holohan, Caitriona, Crawford, Nyree, McIntyre, Alex J., Roberts, Jamie Z., Wappett, Mark, McDade, Simon S., Longley, Daniel B., Coyle, Victoria

المصدر: Ferris , J , Espona-Fiedler , M , Hamilton , C , Holohan , C , Crawford , N , McIntyre , A J , Roberts , J Z , Wappett , M , McDade , S S , Longley , D B & Coyle , V 2020 , ' Pevonedistat (MLN4924): mechanism of cell death induction and therapeutic potential in colorectal cancer : mechanism of cell death induction and therapeutic potential in colorectal cancer ' , Cell death discovery , vol. 6 , no. 1 , 61 , pp. 61 . https://doi.org/10.1038/s41420-020-00296-wTest , https://doi.org/10.1038/s41420-020-00296-wTest

مصطلحات موضوعية: /dk/atira/pure/subjectarea/asjc/2400/2403, name=Immunology, /dk/atira/pure/subjectarea/asjc/2800/2804, name=Cellular and Molecular Neuroscience, /dk/atira/pure/subjectarea/asjc/1300/1307, name=Cell Biology, /dk/atira/pure/subjectarea/asjc/1300/1306, name=Cancer Research, /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

وصف الملف: application/pdf

العلاقة: https://pure.qub.ac.uk/en/publications/4eee8dc3-753e-48d6-9fd4-5735ae49a97aTest

الإتاحة: https://doi.org/10.1038/s41420-020-00296-wTest
https://pure.qub.ac.uk/en/publications/4eee8dc3-753e-48d6-9fd4-5735ae49a97aTest
https://pureadmin.qub.ac.uk/ws/files/219699364/s41420_020_00296_w.pdfTest

المؤلفون: Grinkevitch, Vera (author), Wappett, Mark (author), Crawford, Nyree (author), Price, Stacey (author), Lees, Andrea (author), McCann, Christopher (author), McAllister, Katherine (author), Prehn, Jochen (author), Wessels, L.F.A. (author)

العلاقة: http://www.scopus.com/inward/record.url?scp=85128161167&partnerID=8YFLogxKTest; Molecular Cancer Therapeutics--1535-7163--c7cb0d68-e1e7-4f82-950e-b099fa9d37b6; http://resolver.tudelft.nl/uuid:c0a9df57-b127-4fa9-aaf2-3cdcc5dca58bTest; https://doi.org/10.1158/1535-7163.MCT-21-0532Test

الإتاحة: https://doi.org/10.1158/1535-7163.MCT-21-0532Test
http://resolver.tudelft.nl/uuid:c0a9df57-b127-4fa9-aaf2-3cdcc5dca58bTest