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1دورية أكاديميةAI-guided pipeline for protein-protein interaction drug discovery identifies an SARS-CoV-2 inhibitor
المؤلفون: Trepte, P., Secker, C., Olivet, J., Blavier, J., Kostova, S., Maseko, S.B., Minia, I., Silva Ramos, E., Cassonnet, P., Golusik, S., Zenkner, M., Beetz, S., Liebich, M.J., Scharek, N., Schutz, A., Sperling, M., Lisurek, M., Wang, Y., Spirohn, K., Hao, T., Calderwood, M.A., Hill, D.E., Landthaler, M., Choi, S.G., Twizere, J.C., Vidal, M., Wanker, E.E.
مصطلحات موضوعية: Cancer Research, Function and Dysfunction of the Nervous System, Technology Platforms, Topic 1: Genes, Cells and Cell-Based Medicine, Topic 2: Molecular Processes and Therapies
وصف الملف: application/pdf; other
العلاقة: http://edoc.mdc-berlin.de/23920/1/23920oa.pdfTest; http://edoc.mdc-berlin.de/23920/2/23920suppl.zipTest; AI-guided pipeline for protein-protein interaction drug discovery identifies an SARS-CoV-2 inhibitor. Trepte, P. and Secker, C. and Olivet, J. and Blavier, J. and Kostova, S. and Maseko, S.B. and Minia, I. and Silva Ramos, E. and Cassonnet, P. and Golusik, S. and Zenkner, M. and Beetz, S. and Liebich, M.J. and Scharek, N. and Schutz, A. and Sperling, M. and Lisurek, M. and Wang, Y. and Spirohn, K. and Hao, T. and Calderwood, M.A. and Hill, D.E. and Landthaler, M. and Choi, S.G. and Twizere, J.C. and Vidal, M. and Wanker, E.E. Molecular Systems Biology 20 (4): 428-457. 2 April 2024
الإتاحة: https://doi.org/10.1038/s44320-024-00019-8Test
http://edoc.mdc-berlin.de/23920Test/
https://edoc.mdc-berlin.de/23920Test/
http://edoc.mdc-berlin.de/23920/1/23920oa.pdfTest
http://edoc.mdc-berlin.de/23920/2/23920suppl.zipTest -
2دورية أكاديمية
المؤلفون: Boeddrich, A., Haenig, C., Neuendorf, N., Blanc, E., Ivanov, A., Kirchner, M., Schleumann, P., Bayraktaroğlu, I., Richter, M., Molenda, C.M., Sporbert, A., Zenkner, M., Schnoegl, S., Suenkel, C., Schneider, L.S., Rybak-Wolf, A., Kochnowsky, B., Byrne, L.M., Wild, E.J., Nielsen, J.E., Dittmar, G., Peters, O., Beule, D., Wanker, E.E.
مصطلحات موضوعية: Function and Dysfunction of the Nervous System, Technology Platforms, Topic 1: Genes, Cells and Cell-Based Medicine, Topic 2: Molecular Processes and Therapies, Topic 3: Integrative Biomedicine
وصف الملف: application/pdf; other
العلاقة: http://edoc.mdc-berlin.de/23558/1/23558oa.pdfTest; http://edoc.mdc-berlin.de/23558/7/23558suppl.zipTest; A proteomics analysis of 5xFAD mouse brain regions reveals the lysosome-associated protein Arl8b as a candidate biomarker for Alzheimer's disease. Boeddrich, A. and Haenig, C. and Neuendorf, N. and Blanc, E. and Ivanov, A. and Kirchner, M. and Schleumann, P. and Bayraktaroğlu, I. and Richter, M. and Molenda, C.M. and Sporbert, A. and Zenkner, M. and Schnoegl, S. and Suenkel, C. and Schneider, L.S. and Rybak-Wolf, A. and Kochnowsky, B. and Byrne, L.M. and Wild, E.J. and Nielsen, J.E. and Dittmar, G. and Peters, O. and Beule, D. and Wanker, E.E. Genome Medicine 15 (1): 50. 20 July 2023
الإتاحة: https://doi.org/10.1186/s13073-023-01206-2Test
http://edoc.mdc-berlin.de/23558Test/
https://edoc.mdc-berlin.de/23558Test/
http://edoc.mdc-berlin.de/23558/1/23558oa.pdfTest
http://edoc.mdc-berlin.de/23558/7/23558suppl.zipTest -
3دورية أكاديمية
المؤلفون: Secker, C., Motzny, A.Y., Kostova, S., Buntru, A., Helmecke, L., Reus, L., Steinfort, R., Brusendorf, L., Boddrich, A., Neuendorf, N., Diez, L., Schmieder, P., Schulz, A., Czekelius, C., Wanker, E.E.
مصطلحات موضوعية: Function and Dysfunction of the Nervous System, Topic 2: Molecular Processes and Therapies
وصف الملف: application/pdf
العلاقة: http://edoc.mdc-berlin.de/23358/13/23358oa.pdfTest; http://edoc.mdc-berlin.de/23358/2/23358suppl.pdfTest; The polyphenol EGCG directly targets intracellular amyloid-β aggregates and promotes their lysosomal degradation. Secker, C. and Motzny, A.Y. and Kostova, S. and Buntru, A. and Helmecke, L. and Reus, L. and Steinfort, R. and Brusendorf, L. and Boddrich, A. and Neuendorf, N. and Diez, L. and Schmieder, P. and Schulz, A. and Czekelius, C. and Wanker, E.E. Journal of Neurochemistry 166 (2): 294-317. 18 July 2023
الإتاحة: https://doi.org/10.1111/jnc.15842Test
http://edoc.mdc-berlin.de/23358Test/
https://edoc.mdc-berlin.de/23358Test/
http://edoc.mdc-berlin.de/23358/13/23358oa.pdfTest
http://edoc.mdc-berlin.de/23358/2/23358suppl.pdfTest -
4دورية أكاديمية
المؤلفون: Miller, D.C., Lisowski, P., Genehr, C., Wanker, E.E., Priller, J., Prigione, A., Diecke, S.
مصطلحات موضوعية: Cancer Research, Function and Dysfunction of the Nervous System, Technology Platforms, Topic 1: Genes, Cells and Cell-Based Medicine, Topic 2: Molecular Processes and Therapies, Topic 3: Integrative Biomedicine
وصف الملف: application/pdf; application/msword
العلاقة: http://edoc.mdc-berlin.de/23172/1/23172oa.pdfTest; http://edoc.mdc-berlin.de/23172/2/23172suppl.docxTest; Generation of an induced pluripotent stem cell line from a Huntington's disease patient with a long HTT-PolyQ sequence. Miller, D.C. and Lisowski, P. and Genehr, C. and Wanker, E.E. and Priller, J. and Prigione, A. and Diecke, S. Stem Cell Research 68 : 103056. April 2023
الإتاحة: https://doi.org/10.1016/j.scr.2023.103056Test
http://edoc.mdc-berlin.de/23172Test/
https://edoc.mdc-berlin.de/23172Test/
http://edoc.mdc-berlin.de/23172/1/23172oa.pdfTest
http://edoc.mdc-berlin.de/23172/2/23172suppl.docxTest -
5دورية أكاديمية
المؤلفون: Smith, E.J., Sathasivam, K., Landles, C., Osborne, G.F., Mason, M.A., Gomez-Paredes, C., Taxy, B.A., Milton, R.E., Ast, A., Schindler, F., Zhang, C., Duan, W., Wanker, E.E., Bates, G.P.
مصطلحات موضوعية: Function and Dysfunction of the Nervous System, Topic 2: Molecular Processes and Therapies
وصف الملف: application/pdf
العلاقة: http://edoc.mdc-berlin.de/23106/1/23106oa.pdfTest; http://edoc.mdc-berlin.de/23106/2/23106suppl.pdfTest; Early detection of exon 1 huntingtin aggregation in zQ175 brains by molecular and histological approaches. Smith, E.J. and Sathasivam, K. and Landles, C. and Osborne, G.F. and Mason, M.A. and Gomez-Paredes, C. and Taxy, B.A. and Milton, R.E. and Ast, A. and Schindler, F. and Zhang, C. and Duan, W. and Wanker, E.E. and Bates, G.P. Brain Communications 5 (1): fcad010. 20 January 2023
الإتاحة: https://doi.org/10.1093/braincomms/fcad010Test
http://edoc.mdc-berlin.de/23106Test/
https://edoc.mdc-berlin.de/23106Test/
http://edoc.mdc-berlin.de/23106/1/23106oa.pdfTest
http://edoc.mdc-berlin.de/23106/2/23106suppl.pdfTest -
6كتاب
المؤلفون: Silva Ramos, E., Greco, T.M., Cristea, I.M., Wanker, E.E.
المساهمون: Yang, W.X., Thompson, L.M., Thompson, M.
مصطلحات موضوعية: Function and Dysfunction of the Nervous System, Topic 2: Molecular Processes and Therapies
العلاقة: Huntingtin protein–protein interactions: From biology to therapeutic targets. Silva Ramos, E. and Greco, T.M. and Cristea, I.M. and Wanker, E.E. In: Huntington's Disease. Elsevier, New York, NY, USA, 159-186. ISBN pub.1168955041 16 February 2024
الإتاحة: https://doi.org/10.1016/B978-0-323-95672-7.00016-9Test
http://edoc.mdc-berlin.de/24296Test/
https://edoc.mdc-berlin.de/24296Test/ -
7دورية أكاديمية
المؤلفون: Miller, D.C., Lisowski, P., Lickfett, S., Mlody, B., Bünning, M., Genehr, C., Ulrich, C., Wanker, E.E., Diecke, S., Priller, J., Prigione, A.
مصطلحات موضوعية: Cancer Research, Function and Dysfunction of the Nervous System, Technology Platforms, Topic 1: Genes, Cells and Cell-Based Medicine, Topic 2: Molecular Processes and Therapies, Topic 3: Integrative Biomedicine
وصف الملف: application/pdf
العلاقة: http://edoc.mdc-berlin.de/22914/1/22914oa.pdfTest; http://edoc.mdc-berlin.de/22914/2/22914suppl.pdfTest; Generation of induced pluripotent stem cells from three individuals with Huntington's disease. Miller, D.C. and Lisowski, P. and Lickfett, S. and Mlody, B. and Bünning, M. and Genehr, C. and Ulrich, C. and Wanker, E.E. and Diecke, S. and Priller, J. and Prigione, A. Stem Cell Research 65 : 102976. December 2022
الإتاحة: https://doi.org/10.1016/j.scr.2022.102976Test
http://edoc.mdc-berlin.de/22914Test/
https://edoc.mdc-berlin.de/22914Test/
http://edoc.mdc-berlin.de/22914/1/22914oa.pdfTest
http://edoc.mdc-berlin.de/22914/2/22914suppl.pdfTest -
8مراجعة
المؤلفون: Bonsor, M., Ammar, O., Schnoegl, S., Wanker, E.E., Silva Ramos, E.
مصطلحات موضوعية: Function and Dysfunction of the Nervous System, Topic 2: Molecular Processes and Therapies
وصف الملف: application/pdf
العلاقة: http://edoc.mdc-berlin.de/24300/1/24300oa.pdfTest; Polyglutamine disease proteins: Commonalities and differences in interaction profiles and pathological effects. Bonsor, M. and Ammar, O. and Schnoegl, S. and Wanker, E.E. and Silva Ramos, E. Proteomics : e2300114. 14 April 2024 (In Press)
الإتاحة: https://doi.org/10.1002/pmic.202300114Test
http://edoc.mdc-berlin.de/24300Test/
https://edoc.mdc-berlin.de/24300Test/
http://edoc.mdc-berlin.de/24300/1/24300oa.pdfTest -
9تقرير
المؤلفون: Alteen, M.G., Deme, J.C., Alvarez, C.P., Loppnau, P., Hutchinson, A., Seitova, A., Chandrasekaran, R., Silva Ramos, E., Secker, C., Alqazzaz, M., Wanker, E.E., Lea, S.M., Arrowsmith, C.H., Harding, R.J.
مصطلحات موضوعية: Function and Dysfunction of the Nervous System, Topic 2: Molecular Processes and Therapies
وصف الملف: application/pdf; other
العلاقة: http://edoc.mdc-berlin.de/22854/1/22854oa.pdfTest; http://edoc.mdc-berlin.de/22854/2/22854suppl.zipTest; Expanding the Huntington’s disease research toolbox; validated subdomain protein constructs for biochemical and structural investigation of huntingtin. Alteen, M.G. and Deme, J.C. and Alvarez, C.P. and Loppnau, P. and Hutchinson, A. and Seitova, A. and Chandrasekaran, R. and Silva Ramos, E. and Secker, C. and Alqazzaz, M. and Wanker, E.E. and Lea, S.M. and Arrowsmith, C.H. and Harding, R.J. bioRxiv : 2022.11.21.516512. 22 November 2022
الإتاحة: https://doi.org/10.1101/2022.11.21.516512Test
http://edoc.mdc-berlin.de/22854Test/
https://edoc.mdc-berlin.de/22854Test/
http://edoc.mdc-berlin.de/22854/1/22854oa.pdfTest
http://edoc.mdc-berlin.de/22854/2/22854suppl.zipTest -
10دورية أكاديمية
المؤلفون: Secker, C., Kostova, S., Niederlechner, H., Beetz, S., Wendland, I., Liebich, M.J., Polzer, O., Groh, M., Schnoegl, S., Trepte, P., Wanker, E.E.
مصطلحات موضوعية: Function and Dysfunction of the Nervous System, Topic 2: Molecular Processes and Therapies
وصف الملف: application/pdf
العلاقة: http://edoc.mdc-berlin.de/21000/1/21000oa.pdfTest; CellFIE: CRISPR- and cell fusion-based two-hybrid interaction mapping of endogenous proteins. Secker, C. and Kostova, S. and Niederlechner, H. and Beetz, S. and Wendland, I. and Liebich, M.J. and Polzer, O. and Groh, M. and Schnoegl, S. and Trepte, P. and Wanker, E.E. Journal of Molecular Biology 433 (24): 167305. 3 December 2021
الإتاحة: https://doi.org/10.1016/j.jmb.2021.167305Test
http://edoc.mdc-berlin.de/21000Test/
https://edoc.mdc-berlin.de/21000Test/
http://edoc.mdc-berlin.de/21000/1/21000oa.pdfTest
