المؤلفون: Christopher Negron, Joyce Fang, Michael J. McPherson, W. Blaine Stine, Andrew J. McCluskey

المصدر: mAbs, Vol 14, Iss 1 (2022)

مصطلحات موضوعية: Developability, drug discovery, machine learning, repertoire antibodies, therapeutic antibodies, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1942-0862Test; https://doaj.org/toc/1942-0870Test

الوصول الحر: https://doaj.org/article/e9eca828fb774c6fa14891a2fc97fbafTest

المؤلفون: Barbara L. Trommer, Chirag Shah, Sung Hwan Yun, Georgi Gamkrelidze, Emily S. Pasternak, W. Blaine Stine, Arlene Manelli, Patrick Sullivan, Joseph F. Pasternak, Mary Jo LaDu

المصدر: Neurobiology of Disease, Vol 18, Iss 1, Pp 75-82 (2005)

مصطلحات موضوعية: ApoE, Amyloid-β, Long-term potentiation (LTP), Dentate gyrus, Alzheimer disease, ApoE transgenic mice, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S0969996104001986Test; https://doaj.org/toc/1095-953XTest

الوصول الحر: https://doaj.org/article/8ecce7e34bf64738bc47a3380f0070e8Test

المؤلفون: Baoling Ying, Pei Yong Shi, Spencer Stumpf, W. Blaine Stine, Charles Y. Chiu, James Brett Case, Davide Corti, Mehul S. Suthar, Sean P. J. Whelan, Laura A. VanBlargan, Lindsay Droit, Raul Andino, Adrianus C. M. Boon, Daved H. Fremont, Seth J. Zost, Miguel Garcia Knight, Zhuoming Liu, Rita E. Chen, Xuping Xie, Traci L. Bricker, Ali H. Ellebedy, John M. Errico, Michael S. Diamond, Lisa A. Purcell, Ishmael D. Aziati, Tamarand L. Darling, David Wang, Pavlo Gilchuk, Meredith E. Davis-Gardner, Scott A. Handley, Swathi Shrihari, James E. Crowe, Emma S. Winkler, Astha Joshi

المصدر: Nature
Nature, vol 596, iss 7870
Research Square
article-version (status) pre
article-version (number) 1

مصطلحات موضوعية: Male, Antibodies, Viral, Transgenic, Mice, Monoclonal, Chlorocebus aethiops, antibodies, Viral, Neutralizing, Lung, Multidisciplinary, Serine Endopeptidases, Antibodies, Monoclonal, Spike Glycoprotein, Infectious Diseases, Spike Glycoprotein, Coronavirus, Pneumonia & Influenza, Female, Angiotensin-Converting Enzyme 2, Antibody, Post-Exposure Prophylaxis, Infection, Biotechnology, Genetically modified mouse, General Science & Technology, medicine.drug_class, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Mice, Transgenic, Biology, Monoclonal antibody, Antibodies, Article, Vaccine Related, Neutralization Tests, In vivo, Biodefense, medicine, Animals, Humans, Potency, variations, Gene, Vero Cells, Mesocricetus, SARS-CoV-2, Prevention, COVID-19, Pneumonia, biology.organism_classification, Antibodies, Neutralizing, Virology, In vitro, Coronavirus, Emerging Infectious Diseases, Cell culture, Vero cell, biology.protein, SARS-CoV-2 variant strains, Pre-Exposure Prophylaxis, Immunization

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43df015511f1cac2dbd9f25ef2adcd7dTest
https://pubmed.ncbi.nlm.nih.gov/34153975Test

المؤلفون: Tariq Ghayur, W. Blaine Stine, Dana I. Filoti

المصدر: Development of Biopharmaceutical Drug-Device Products ISBN: 9783030314149

مصطلحات موضوعية: Computer science, Variable domain, Computational biology, DUAL (cognitive architecture), Design for manufacturability

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::a2cc5f407a25a2c2285c77dab42eb296Test
https://doi.org/10.1007/978-3-030-31415-6_5Test

المؤلفون: Georgi Gamkrelidze, W. Blaine Stine, Sung Hwan Yun, Joseph F. Pasternak, Barbara L. Trommer, Mary Jo LaDu, Patrick Sullivan

المصدر: Neuroscience Letters. 403:162-165

مصطلحات موضوعية: Male, Patch-Clamp Techniques, Long-Term Potentiation, Central nervous system, Action Potentials, In Vitro Techniques, Hippocampal formation, Biology, Article, Mice, Biopolymers, Neuroplasticity, medicine, Animals, Patch clamp, Neurons, Amyloid beta-Peptides, General Neuroscience, Dentate gyrus, Long-term potentiation, Afterhyperpolarization, medicine.disease, Peptide Fragments, Mice, Inbred C57BL, medicine.anatomical_structure, Dentate Gyrus, Alzheimer's disease, Neuroscience

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39ccdf3b4b048a2f504b8b857a4c86cfTest
https://doi.org/10.1016/j.neulet.2006.04.065Test

المؤلفون: Catherine A. Reardon, Mary Jo LaDu, Guojun Bu, Godfrey S. Getz, Masaaki Narita, W. Blaine Stine

المصدر: Biochemistry. 45:381-390

مصطلحات موضوعية: Apolipoprotein E, Apolipoprotein E4, Apolipoprotein E3, Plasma protein binding, Ligands, Biochemistry, Article, Cell Line, Apolipoproteins E, Iodine Radioisotopes, Mice, Animals, Humans, Receptor, Chemistry, HEK 293 cells, Fibroblasts, Ligand (biochemistry), Receptors, LDL, LDL receptor, Chromatography, Gel, lipids (amino acids, peptides, and proteins), Ultracentrifugation, Low Density Lipoprotein Receptor-Related Protein-1, Protein Binding, Lipoprotein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7181242087cc91a6ea6ea23ae5ddfeb8Test
https://doi.org/10.1021/bi051765sTest

المؤلفون: Yu Min Kuo, David M. Stern, W. Blaine Stine, Ann Marie Schmidt, Alex E. Roher, Shi Du Yan, Michael O. Chaney, Dean C. Luehrs, Chera Esh, Afroza Rahman, Tyler A. Kokjohn

المصدر: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1741(1-2):199-205

مصطلحات موضوعية: Glycation End Products, Advanced, Models, Molecular, endocrine system diseases, Amyloid beta, IgG, Receptor for Advanced Glycation End Products, Molecular modeling, Microscopy, Atomic Force, Protein Structure, Secondary, RAGE (receptor), 03 medical and health sciences, Atomic force microscopy, 0302 clinical medicine, Protein structure, Glycation, Alzheimer Disease, mental disorders, Humans, Amino Acid Sequence, Disulfides, cardiovascular diseases, Receptors, Immunologic, Receptor, Peptide sequence, Transcription factor, Molecular Biology, Neuroinflammation, 030304 developmental biology, 0303 health sciences, Amyloid beta-Peptides, biology, Chemistry, nutritional and metabolic diseases, Alzheimer's disease, Peptide Fragments, RAGE, nervous system diseases, 3. Good health, Protein Structure, Tertiary, Biochemistry, Solubility, Immunoglobulin G, biology.protein, Biophysics, cardiovascular system, Molecular Medicine, Dimerization, human activities, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93f5dac36a383c0f27dd10d9f22bd714Test

المؤلفون: Chirag Shah, Georgi Gamkrelidze, Joseph F. Pasternak, W. Blaine Stine, Sung Hwan Yun, Mary Jo LaDu, Arlene M. Manelli, Emily S. Pasternak, Patrick Sullivan, Barbara L. Trommer

المصدر: Neurobiology of Disease, Vol 18, Iss 1, Pp 75-82 (2005)

مصطلحات موضوعية: Apolipoprotein E, Gene isoform, Male, medicine.medical_specialty, Apolipoprotein E2, Cell Survival, Protein Conformation, Apolipoprotein E4, Long-Term Potentiation, ApoE transgenic mice, Apolipoprotein E3, Mice, Transgenic, Hippocampal formation, Hippocampus, lcsh:RC321-571, Pathogenesis, Mice, Apolipoproteins E, Organ Culture Techniques, Internal medicine, mental disorders, medicine, Animals, Protein Isoforms, Amyloid-β, Dentate gyrus, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Mice, Knockout, Long-term potentiation (LTP), Amyloid beta-Peptides, Chemistry, Long-term potentiation, medicine.disease, Peptide Fragments, Molecular Weight, Endocrinology, Neuroprotective Agents, nervous system, Neurology, lipids (amino acids, peptides, and proteins), Alzheimer's disease, Cellular model, Alzheimer disease, Neuroscience, ApoE

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10ba2b3bcb042d5dc435120603922202Test
http://www.sciencedirect.com/science/article/pii/S0969996104001986Test

المؤلفون: Mary Jo LaDu, Arlene M. Manelli, Grant A. Krafft, W. Blaine Stine, Lorinda K. Baker, Karie N. Dahlgren

المصدر: Journal of Biological Chemistry. 277:32046-32053

مصطلحات موضوعية: Amyloid, Cell Survival, Mutant, Peptide, Biology, Microscopy, Atomic Force, Fibril, Biochemistry, Oligomer, Neuroblastoma, chemistry.chemical_compound, Alzheimer Disease, Tumor Cells, Cultured, medicine, Humans, Molecular Biology, Neurons, chemistry.chemical_classification, Amyloid beta-Peptides, Neurodegeneration, Wild type, Cell Biology, medicine.disease, Peptide Fragments, chemistry, Alzheimer's disease

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a50c189ded797f00907380a7e5d363ceTest
https://doi.org/10.1074/jbc.m201750200Test

المؤلفون: Jerome Baudry, Michael O. Chaney, Yu Min Kuo, Alex E. Roher, W. Blaine Stine, Mark R. Emmerling

المصدر: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1502:31-43

مصطلحات موضوعية: Models, Molecular, Magnetic Resonance Spectroscopy, Stereochemistry, Dimer, Molecular Sequence Data, Nucleation, Microscopy, Atomic Force, Fibril, Antiparallel (biochemistry), Protein filament, Amyloid beta-Protein Precursor, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, X-Ray Diffraction, Alzheimer Disease, Endopeptidases, Animals, Aspartic Acid Endopeptidases, Humans, Molecule, Amino Acid Sequence, Molecular Biology, 030304 developmental biology, 0303 health sciences, Amyloid beta-Peptides, biology, Cell Membrane, AβPP, Membrane, Neurofibrillary Tangles, Secretase, chemistry, biology.protein, Molecular Medicine, Amyloid Precursor Protein Secretases, Peptides, Dimerization, Oligopeptides, Alzheimer’s disease, Molecular structure, Amyloid precursor protein secretase, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b045d03bb20fa47c8b6b7bbf9fe2484Test
https://doi.org/10.1016/s0925-4439Test(00)00030-2