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1دورية أكاديمية
المؤلفون: Ngo, Khoa, Mateos, Diego Lopez, Han, Yanxiao, Rouen, Kyle C, Ahn, Surl-Hee, Wulff, Heike, Clancy, Colleen E, Yarov-Yarovoy, Vladimir, Vorobyov, Igor
المصدر: The Journal of General Physiology. 156(2)
مصطلحات موضوعية: Biomedical and Clinical Sciences, Neurosciences, Chronic Pain, Networking and Information Technology R&D (NITRD), Bioengineering, Pain Research, Underpinning research, Aetiology, 2.1 Biological and endogenous factors, Development of treatments and therapeutic interventions, 1.1 Normal biological development and functioning, 5.1 Pharmaceuticals, Humans, Action Potentials, Interneurons, Molecular Dynamics Simulation, Pain, NAV1.7 Voltage-Gated Sodium Channel, Spider Venoms, Peptides, Physiology, Medical Physiology, Biochemistry and cell biology, Zoology, Medical physiology
وصف الملف: application/pdf
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2دورية أكاديمية
المؤلفون: Han, Yanxiao, Dawson, John RD, DeMarco, Kevin R, Rouen, Kyle C, Bekker, Slava, Yarov-Yarovoy, Vladimir, Clancy, Colleen E, Xiang, Yang K, Vorobyov, Igor
المصدر: Proceedings of the National Academy of Sciences of the United States of America. 120(10)
مصطلحات موضوعية: Biochemistry and Cell Biology, Chemical Sciences, Biological Sciences, Neurosciences, 1.1 Normal biological development and functioning, Underpinning research, Generic health relevance, GTP-Binding Protein alpha Subunits, Gs, Receptors, Adrenergic, beta-2, Ligands, Signal Transduction, Molecular Dynamics Simulation, Norepinephrine, G protein-coupled receptor, G protein, norepinephrine, sympathetic nervous system, molecular dynamics
وصف الملف: application/pdf
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3دورية أكاديمية
المؤلفون: Emigh Cortez, Aiyana, DeMarco, Kevin, Furutani, Kazuharu, Bekker, Slava, Sack, Jon, Wulff, Heike, Clancy, Colleen, Vorobyov, Igor, Yarov-Yarovoy, Vladimir
مصطلحات موضوعية: Rosetta, drug block, hERG channel, potassium channel, state-dependent
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/2vk5v4zsTest
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4دورية أكاديمية
المؤلفون: Tyagi, Anu, Ahmed, Tofayel, Jian, Shi, Bajaj, Saumya, Ong, Seow Theng, Goay, Stephanie Shee Min, Zhao, Yue, Vorobyov, Igor, Tian, Changlin, Chandy, K George, Bhushan, Shashi
المصدر: Proceedings of the National Academy of Sciences of the United States of America. 119(5)
مصطلحات موضوعية: Inorganic Chemistry, Chemical Sciences, Amino Acid Sequence, Binding Sites, Humans, Ion Channel Gating, Kv1.3 Potassium Channel, Membrane Potentials, Microscopy, Electron, Models, Molecular, Molecular Conformation, Potassium, Potassium Channels, Potassium Channels, Voltage-Gated, Sequence Alignment, ion channels, potassium channels, selectivity filter, ShK, dalazatide
وصف الملف: application/pdf
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5دورية أكاديمية
المؤلفون: Yang, Pei-Chi, Jeng, Mao-Tsuen, Yarov-Yarovoy, Vladimir, Santana, L. Fernando, Vorobyov, Igor, Clancy, Colleen E.
المساهمون: NIH Common Fund, NHLBI, American Heart Association Inc, Oracle Corporation
المصدر: JACC: Clinical Electrophysiology ; volume 10, issue 2, page 359-364 ; ISSN 2405-500X
الإتاحة: https://doi.org/10.1016/j.jacep.2023.10.024Test
https://api.elsevier.com/content/article/PII:S2405500X23008174?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S2405500X23008174?httpAccept=text/plainTest -
6دورية أكاديمية
المؤلفون: Maly, Jan, Emigh, Aiyana M, DeMarco, Kevin R, Furutani, Kazuharu, Sack, Jon T, Clancy, Colleen E, Vorobyov, Igor, Yarov-Yarovoy, Vladimir
مصطلحات موضوعية: Medical Physiology, Biomedical and Clinical Sciences, Heart Disease, Cardiovascular, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, hERG channel, potassium channel, inactivation, drug block, Rosetta, Pharmacology and Pharmaceutical Sciences, Pharmacology and pharmaceutical sciences
وصف الملف: application/pdf
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7دورية أكاديمية
المؤلفون: DeMarco, Kevin R, Yang, Pei-Chi, Singh, Vikrant, Furutani, Kazuharu, Dawson, John RD, Jeng, Mao-Tsuen, Fettinger, James C, Bekker, Slava, Ngo, Van A, Noskov, Sergei Y, Yarov-Yarovoy, Vladimir, Sack, Jon T, Wulff, Heike, Clancy, Colleen E, Vorobyov, Igor
مصطلحات موضوعية: Arrhythmia, Beta-blocker, Enantiomer, Ion channel, Molecular dynamics, Stereochemistry, Cardiovascular, Heart Disease, 5.1 Pharmaceuticals, Cardiovascular System & Hematology, Cardiorespiratory Medicine and Haematology, Medical Physiology
الوصول الحر: https://escholarship.org/uc/item/5j4818hmTest
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8دورية أكاديمية
المؤلفون: Aghasafari, Parya, Yang, Pei-Chi, Kernik, Divya C, Sakamoto, Kazuho, Kanda, Yasunari, Kurokawa, Junko, Vorobyov, Igor, Clancy, Colleen E
مصطلحات موضوعية: Biomedical and Clinical Sciences, Heart Disease, Stem Cell Research - Induced Pluripotent Stem Cell - Human, Cardiovascular, Machine Learning and Artificial Intelligence, Clinical Research, Stem Cell Research, Stem Cell Research - Induced Pluripotent Stem Cell, Networking and Information Technology R&D (NITRD), Action Potentials, Algorithms, Cell Differentiation, Computer Simulation, Deep Learning, ERG1 Potassium Channel, Electrophysiologic Techniques, Cardiac, Electrophysiological Phenomena, Gene Expression Regulation, Humans, Induced Pluripotent Stem Cells, Models, Biological, Myocytes, Cardiac, Phenethylamines, Sulfonamides, arrhythmias, artificial intelligence, computational biology, deep learning, human, machine learning, pharmacology, regenerative medicine, stem cells, systems biology, Biochemistry and Cell Biology, Biological sciences, Biomedical and clinical sciences, Health sciences
وصف الملف: application/pdf
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9دورية أكاديمية
المؤلفون: Yang, Pei-Chi, DeMarco, Kevin R, Aghasafari, Parya, Jeng, Mao-Tsuen, Dawson, John RD, Bekker, Slava, Noskov, Sergei Y, Yarov-Yarovoy, Vladimir, Vorobyov, Igor, Clancy, Colleen E
المصدر: Circulation Research. 126(8)
مصطلحات موضوعية: Pharmacology and Pharmaceutical Sciences, Biomedical and Clinical Sciences, Machine Learning and Artificial Intelligence, Cardiovascular, Networking and Information Technology R&D (NITRD), Heart Disease, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Anti-Arrhythmia Agents, Arrhythmias, Cardiac, Cardiotoxicity, Cardiotoxins, Computer Simulation, Drug Discovery, ERG1 Potassium Channel, Female, Humans, Long QT Syndrome, Machine Learning, Male, Moxifloxacin, Myocytes, Cardiac, Phenethylamines, Protein Structure, Secondary, Sulfonamides, Topoisomerase II Inhibitors, arrhythmias, cardiac electrophysiology, computational biology, drug-induced cardiotoxicity, multiscale, Cardiorespiratory Medicine and Haematology, Clinical Sciences, Cardiovascular System & Hematology, Cardiovascular medicine and haematology, Clinical sciences
وصف الملف: application/pdf
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10دورية أكاديمية
المؤلفون: Miranda, Williams E, DeMarco, Kevin R, Guo, Jiqing, Duff, Henry J, Vorobyov, Igor, Clancy, Colleen E, Noskov, Sergei Yu
المصدر: Proceedings of the National Academy of Sciences of the United States of America. 117(6)
مصطلحات موضوعية: Medical Physiology, Biomedical and Clinical Sciences, Physical Sciences, Genetics, Cardiovascular, Networking and Information Technology R&D (NITRD), Generic health relevance, Amino Acid Motifs, ERG1 Potassium Channel, Gain of Function Mutation, Humans, Kinetics, Long QT Syndrome, Mutation, Missense, Potassium, Protein Domains, Protein Structure, Secondary, ion channels, molecular dynamics, human ether-a-go-go channel, long-QT syndrome, human ether-á-go-go channel
وصف الملف: application/pdf