نتائج البحث - "Voltage-Gated Sodium Channel Blocker"

1

دورية أكاديمية

Glutamatergic and GABAergic reactivity and cognition in 22q11.2 deletion syndrome and healthy volunteers: A randomized double-blind 7-Tesla pharmacological MRS study

المؤلفون: Vingerhoets, Claudia, Tse, Desmond Hy, van Oudenaren, Mathilde, Hernaus, Dennis, van Duin, Esther, Zinkstok, Janneke, Ramaekers, Johannes G, Jansen, Jacobus Fa, McAlonan, Grainne, van Amelsvoort, Therese

المساهمون: Ontwikkelingsstoornissen Med.

مصطلحات موضوعية: 22q11.2DS, GABA, Glutmate, H-MRS, cognition, riluzole, voltage-gated sodium channel blocker, 2DS, 22q11, H-1-MRS, Psychiatry and Mental health, Pharmacology (medical), Pharmacology, Journal Article

وصف الملف: application/pdf

العلاقة: https://dspace.library.uu.nl/handle/1874/439814Test

الإتاحة: https://dspace.library.uu.nl/handle/1874/439814Test

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2

دورية أكاديمية

Glutamatergic and GABAergic reactivity and cognition in 22q11.2 deletion syndrome and healthy volunteers:A randomized double-blind 7-Tesla pharmacological MRS study

المؤلفون: Vingerhoets, Claudia, Tse, Desmond H.Y., van Oudenaren, Mathilde, Hernaus, Dennis, van Duin, Esther, Zinkstok, Janneke, Ramaekers, Johannes G., Jansen, Jacobus F.A., McAlonan, Grainne, van Amelsvoort, Therese

المصدر: Vingerhoets , C , Tse , D H Y , van Oudenaren , M , Hernaus , D , van Duin , E , Zinkstok , J , Ramaekers , J G , Jansen , J F A , McAlonan , G & van Amelsvoort , T 2020 , ' Glutamatergic and GABAergic reactivity and cognition in 22q11.2 deletion syndrome and healthy volunteers : A randomized double-blind 7-Tesla pharmacological MRS study ' , Journal of Psychopharmacology , vol. 34 , no. 8 , pp. 856-863 . https://doi.org/10.1177/0269881120922977Test

مصطلحات موضوعية: H-MRS, 22q11.2DS, cognition, GABA, Glutmate, riluzole, voltage-gated sodium channel blocker

الإتاحة: https://doi.org/10.1177/0269881120922977Test
https://kclpure.kcl.ac.uk/portal/en/publications/f8d552b2-92e0-4356-8b68-745485a09f50Test
http://www.scopus.com/inward/record.url?scp=85085279679&partnerID=8YFLogxKTest

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3

دورية أكاديمية

NMR structure of μ-conotoxin GIIIC : leucine 18 induces local repacking of the N-terminus resulting in reduced NaV channel potency

المؤلفون: Harvey, Peta J, Kurniawan, Nyoman D, Finol-Urdaneta, Rocio K, McArthur, Jeffrey R, Van Lysebetten, Dorien, Dash, Thomas S, Hill, Justine M, Adams, David J, Durek, Thomas, Craik, David J

المصدر: MOLECULES ; ISSN: 1420-3049

مصطلحات موضوعية: Biology and Life Sciences, Chemistry, mu-conotoxins, voltage-gated sodium channel blocker, NMR, protein structure, SODIUM-CHANNELS, BINDING-SITE, MUSCLE, TETRODOTOXIN, BLOCKER, ARRANGEMENT, SENSITIVITY, INHIBITOR, SUBTYPES

وصف الملف: application/pdf

العلاقة: https://biblio.ugent.be/publication/8601313Test; http://hdl.handle.net/1854/LU-8601313Test; http://dx.doi.org/10.3390/molecules23102715Test; https://biblio.ugent.be/publication/8601313/file/8601315Test

الإتاحة: https://doi.org/10.3390/molecules23102715Test
https://biblio.ugent.be/publication/8601313Test
http://hdl.handle.net/1854/LU-8601313Test
https://biblio.ugent.be/publication/8601313/file/8601315Test

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4

دورية أكاديمية

NMR Structure of μ-Conotoxin GIIIC: Leucine 18 Induces Local Repacking of the N-Terminus Resulting in Reduced NaV Channel Potency

المؤلفون: Peta J. Harvey, Nyoman D. Kurniawan, Rocio K. Finol-Urdaneta, Jeffrey R. McArthur, Dorien Van Lysebetten, Thomas S. Dash, Justine M. Hill, David J. Adams, Thomas Durek, David J. Craik

المصدر: Molecules; Volume 23; Issue 10; Pages: 2715

مصطلحات موضوعية: μ-conotoxins, voltage-gated sodium channel blocker, NMR, protein structure

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Medicinal Chemistry; https://dx.doi.org/10.3390/molecules23102715Test

الإتاحة: https://doi.org/10.3390/molecules23102715Test

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5

دورية أكاديمية

Myotonia permanens with Nav1.4-G1306E displays varied phenotypes during course of life

المؤلفون: Lehmann-Horn, Frank, D'Amico, Adele, Bertini, Enrico, Lomonaco, Mauro, Merlini, Luciano, Nelson, Kevin R, Philippi, Heike, Siciliano, Gabriele, Spaans, Frank, Jurkat-Rott, Karin

المساهمون: Lehmann-Horn, Frank, D'Amico, Adele, Bertini, Enrico, Lomonaco, Mauro, Merlini, Luciano, Nelson, Kevin R, Philippi, Heike, Siciliano, Gabriele, Spaans, Frank, Jurkat-Rott, Karin

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/29774303; volume:36; issue:3; firstpage:125; lastpage:134; numberofpages:10; journal:ACTA MYOLOGICA; http://hdl.handle.net/11568/960064Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85040998709; https://www.actamyologica.it/article/myotonia-permanens-with-nav1-4-g1306e-displays-varied-phenotypes-during-course-of-lifeTest/

الإتاحة: http://hdl.handle.net/11568/960064Test
https://www.actamyologica.it/article/myotonia-permanens-with-nav1-4-g1306e-displays-varied-phenotypes-during-course-of-lifeTest/

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6

Glutamatergic and GABAergic reactivity and cognition in 22q11.2 deletion syndrome and healthy volunteers

المؤلفون: Esther D.A. van Duin, Johannes G. Ramaekers, Jacobus F.A. Jansen, Mathilde van Oudenaren, Janneke Zinkstok, Claudia Vingerhoets, Therese van Amelsvoort, Desmond H. Y. Tse, Grainne M. McAlonan, Dennis Hernaus

المساهمون: RS: MHeNs - R2 - Mental Health, Psychiatrie & Neuropsychologie, Promovendi MHN, RS: FPN NPPP II, Section Psychopharmacology, RS: MHeNs - R1 - Cognitive Neuropsychiatry and Clinical Neuroscience, Beeldvorming, MUMC+: DA BV Klinisch Fysicus (9), MUMC+: MA Med Staf Spec Psychiatrie (9)

المصدر: Journal of Psychopharmacology, 34(8):0269881120922977, 856-863. SAGE Publications Ltd
Journal of Psychopharmacology (Oxford, England)

مصطلحات موضوعية: Male, cognition, Magnetic Resonance Spectroscopy, GABA, 0302 clinical medicine, MAGNETIC-RESONANCE, SCHIZOPHRENIA, Medicine, Attention, Pharmacology (medical), Reactivity (psychology), gamma-Aminobutyric Acid, H-1-MRS, Cross-Over Studies, Cognition, 22q11.2DS, Human brain, HUMAN BRAIN, Original Papers, riluzole, Riluzole, voltage-gated sodium channel blocker, Psychiatry and Mental health, PROTON SPECTROSCOPY, medicine.anatomical_structure, Schizophrenia, GABAergic, Female, 2DS, medicine.drug, Adult, 1H-MRS, Psychosis, QUANTITATION, Glutamic Acid, Gyrus Cinguli, MECHANISMS, Young Adult, 03 medical and health sciences, Glutamatergic, PSYCHOSIS, Double-Blind Method, Memory, DiGeorge Syndrome, Humans, Pharmacology, business.industry, medicine.disease, Corpus Striatum, DYSFUNCTION, 030227 psychiatry, 22q11, Glutmate, nervous system, business, Excitatory Amino Acid Antagonists, Neuroscience, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb6ef202858a40a941741923c6a92015Test
https://doi.org/10.1177/0269881120922977Test

7

دورية أكاديمية

Synthesis and Evaluation of Voltage-Gated Sodium Channel Blocking Pyrroline Derivatives Endowed with Both Antiarrhythmic and Antioxidant Activities

المؤلفون: Carocci, Alessia, Roselli, Mariagrazia, Budriesi, Roberta, Micucci, Matteo, Desaphy, Jean-François, Altamura, Concetta, Cavalluzzi, Maria Maddalena, Toma, Maddalena, Passeri, Giovanna Ilaria, Milani, Gualtiero, Lovece, Angelo, Catalano, Alessia, Bruno, Claudio, De Palma, Annalisa, Corbo, Filomena, Franchini, Carlo, Habtemariam, Solomon, Lentini, Giovanni

المساهمون: Carocci, Alessia, Roselli, Mariagrazia, Budriesi, Roberta, Micucci, Matteo, Desaphy, Jean-Françoi, Altamura, Concetta, Cavalluzzi, Maria Maddalena, Toma, Maddalena, Passeri, Giovanna Ilaria, Milani, Gualtiero, Lovece, Angelo, Catalano, Alessia, Bruno, Claudio, De Palma, Annalisa, Corbo, Filomena, Franchini, Carlo, Habtemariam, Solomon, Lentini, Giovanni

مصطلحات موضوعية: Animal, Anti-Arrhythmia Agent, Antioxidant, Density Functional Theory, Fluorescein, Guinea Pig, Human, Molecular Structure, Pyrrole, Reperfusion Injury, Tumor Cells, Cultured, Voltage-Gated Sodium Channel Blocker, Voltage-Gated Sodium Channels

وصف الملف: ELETTRONICO

العلاقة: info:eu-repo/semantics/altIdentifier/wos/WOS:000583052100001; volume:16; issue:3; firstpage:578; lastpage:588; numberofpages:11; journal:CHEMMEDCHEM; http://hdl.handle.net/11576/2696081Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85094159753

الإتاحة: https://doi.org/10.1002/cmdc.202000692Test
http://hdl.handle.net/11576/2696081Test

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8

Gene-Specific Therapy With Mexiletine Reduces Arrhythmic Events in Patients With Long QT Syndrome Type 3

المؤلفون: Paola Baiardi, Riccardo Maragna, Andrea Mazzanti, Susan P. Etheridge, Valeria Novelli, Mirella Memmi, Nicola Monteforte, Raffaella Bloise, Vincenzo Bagnardi, Silvia G. Priori, Alessandro Faragli, Carlo Napolitano

المساهمون: Mazzanti, A, Maragna, R, Faragli, A, Monteforte, N, Bloise, R, Memmi, M, Novelli, V, Baiardi, P, Bagnardi, V, Etheridge, S, Napolitano, C, Priori, S

المصدر: Journal of the American College of Cardiology

مصطلحات موضوعية: 0301 basic medicine, Male, Administration, Oral, LQTS, long QT syndrome, 030204 cardiovascular system & hematology, Sudden cardiac death, Electrocardiography, 0302 clinical medicine, Retrospective Studie, Heart Rate, Medicine, Child, SCN5A, Original Investigation, medicine.diagnostic_test, Medicine (all), Long QT Syndrome, Treatment Outcome, Anesthesia, Cardiology, beta-blocker, Female, Cardiology and Cardiovascular Medicine, Human, medicine.drug, sodium channel, Adult, medicine.medical_specialty, Adolescent, medicine.drug_class, Long QT syndrome, Mexiletine, QT interval, sudden cardiac death, Follow-Up Studie, Young Adult, 03 medical and health sciences, Internal medicine, Heart rate, Humans, Beta blocker, business.industry, LQT3, long QT syndrome type 3, Retrospective cohort study, Genetic Therapy, medicine.disease, CI, confidence interval, 030104 developmental biology, Voltage-Gated Sodium Channel Blocker, ECG, electrocardiogram, mutation, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb1de409a4fe9c53b9e4678435ef2df0Test

9

دورية أكاديمية

NMR structure of µ-conotoxin GIIIC: Leucine 18 induces local repacking of the N-terminus resulting in reduced Nav channel potency

المؤلفون: Harvey, Peta J., Kurniawan, Nyoman D., Finol-Urdaneta, Rocio K., McArthur, Jeffrey R., Van Lysebetten, Dorien, Dash, Thomas S., Hill, Justine M., Adams, David J., Durek, Thomas, Craik, David J.

مصطلحات موضوعية: NMR, Protein structure, Voltage-gated sodium channel blocker, Μ-conotoxins, 1313 Molecular Medicine, 1601 Chemistry (miscellaneous), 1602 Analytical Chemistry, 1605 Organic Chemistry, 1606 Physical and Theoretical Chemistry, 3002 Drug Discovery, 3003 Pharmaceutical Science

العلاقة: orcid:0000-0003-4735-6242; orcid:0000-0001-6340-182X; orcid:0000-0003-0686-227X; orcid:0000-0003-0007-6796; FL150100146; APP1072113

الإتاحة: https://doi.org/10.3390/molecules23102715Test
https://espace.library.uq.edu.au/view/UQ:e6a88aaTest

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النص الكامل

10

دورية أكاديمية

A Focus on the Synthesis and Pharmacokinetics of Tocainide and its Analogues

المؤلفون: Carocci, Alessia, Corbo, Filomena, Lentini, Giovanni, Cavalluzzi, Maria Maddalena, Franchini, Carlo, Catalano, Alessia

المساهمون: Carocci, Alessia, Corbo, Filomena, Lentini, Giovanni, Cavalluzzi, Maria Maddalena, Franchini, Carlo, Catalano, Alessia

مصطلحات موضوعية: Antiarrhythmic agent, antimyotonic agent, hNav1.4, myotonia, sodium channel blocker, tocainide, Anti-Arrhythmia Agent, Arrhythmias, Cardiac, Half-Life, Human, NAV1.4 Voltage-Gated Sodium Channel, Quantitative Structure-Activity Relationship, Voltage-Gated Sodium Channel Blocker, Biochemistry, Molecular Medicine, Pharmacology, Drug Discovery3003 Pharmaceutical Science, Organic Chemistry

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/29589531; info:eu-repo/semantics/altIdentifier/wos/WOS:000457846900004; volume:25; issue:42; firstpage:5822; lastpage:5834; numberofpages:13; journal:CURRENT MEDICINAL CHEMISTRY; http://hdl.handle.net/11586/227159Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85061863163

الإتاحة: https://doi.org/10.2174/0929867325666180327104320Test
http://hdl.handle.net/11586/227159Test

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