المؤلفون: Arie O. Verkerk, Suzan J. G. Knottnerus, Vincent Portero, Jeannette C. Bleeker, Sacha Ferdinandusse, Kaomei Guan, Lodewijk IJlst, Gepke Visser, Ronald J. A. Wanders, Frits A. Wijburg, Connie R. Bezzina, Isabella Mengarelli, Riekelt H. Houtkooper

المصدر: Frontiers in Pharmacology, Vol 11 (2021)

مصطلحات موضوعية: very long-chain acyl-CoA dehydrogenase, arrhythmia < cardiovascular, acylcarnitines, action potential, human induced pluripotent stem cell derived cardiomyocytes, patients, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fphar.2020.616834/fullTest; https://doaj.org/toc/1663-9812Test

الوصول الحر: https://doaj.org/article/9bf15979cc1e485ca8dbed0f9ba01156Test

المؤلفون: Simona Casini, Maxime Albesa, Zizun Wang, Vincent Portero, Daniela Ross-Kaschitza, Jean-Sébastien Rougier, Gerard A. Marchal, Wendy K. Chung, Connie R. Bezzina, Hugues Abriel, Carol Ann Remme

المصدر: International Journal of Molecular Sciences, Vol 20, Iss 20, p 5033 (2019)

مصطلحات موضوعية: scn5a, ubiquitylation, long qt syndrome, sodium current, nedd4-2, action potential, patch-clamp, mouse model, Biology (General), QH301-705.5, Chemistry, QD1-999

وصف الملف: electronic resource

العلاقة: https://www.mdpi.com/1422-0067/20/20/5033Test; https://doaj.org/toc/1422-0067Test

الوصول الحر: https://doaj.org/article/303d9d696c274f688ffc404464157d77Test

المؤلفون: Vincent Portero, Ronald Wilders, Simona Casini, Flavien Charpentier, Arie O. Verkerk, Carol Ann Remme

المصدر: Frontiers in Physiology, Vol 9 (2018)

مصطلحات موضوعية: transient outward current, sodium current, channels, action potential, myocyte, arrhythmias, Physiology, QP1-981

وصف الملف: electronic resource

العلاقة: http://journal.frontiersin.org/article/10.3389/fphys.2018.00178/fullTest; https://doaj.org/toc/1664-042XTest

الوصول الحر: https://doaj.org/article/98919b467e3f400e9fde754b76f49b31Test

المؤلفون: Vincent Portero, Solena Le Scouarnec, Zeineb Es‐Salah‐Lamoureux, Sophie Burel, Jean‐Baptiste Gourraud, Stéphanie Bonnaud, Pierre Lindenbaum, Floriane Simonet, Jade Violleau, Estelle Baron, Eléonore Moreau, Carol Scott, Stéphanie Chatel, Gildas Loussouarn, Thomas O'Hara, Philippe Mabo, Christian Dina, Hervé Le Marec, Jean‐Jacques Schott, Vincent Probst, Isabelle Baró, Céline Marionneau, Flavien Charpentier, Richard Redon

المصدر: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 6 (2016)

مصطلحات موضوعية: Brugada syndrome, cardiac arrhythmia, clinical electrophysiology, genetics, KCNAB2/Kvβ2, potassium ion channels, Diseases of the circulatory (Cardiovascular) system, RC666-701

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2047-9980Test

الوصول الحر: https://doaj.org/article/b67e2535b2574e7c940289a9f00f97eaTest

المؤلفون: Camille Rolland-Debord, David Lair, Tiphaine Roussey-Bihouée, Dorian Hassoun, Justine Evrard, Marie-Aude Cheminant, Julie Chesné, Faouzi Braza, Guillaume Mahay, Vincent Portero, Christine Sagan, Bruno Pitard, Antoine Magnan

المصدر: PLoS ONE, Vol 9, Iss 1, p e85976 (2014)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

العلاقة: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24497934/pdf/?tool=EBITest; https://doaj.org/toc/1932-6203Test

الوصول الحر: https://doaj.org/article/6b1f31557e3143d0a1b8ff42dd6b6c3eTest

المؤلفون: Gerard A Marchal, Niels Galjart, Vincent Portero, Carol Ann Remme

المصدر: Cardiovascular Research.

مصطلحات موضوعية: Physiology, Physiology (medical), Cardiology and Cardiovascular Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::b3bf5e02d5bf7f4b71976480dcdd425aTest
https://doi.org/10.1093/cvr/cvad052Test

المؤلفون: Simona Casini, Vincent Portero, Gerard A Marchal, Carol Ann Remme, Joris R. de Groot, Fransisca A. Nariswari, Kaomei Guan, Antoine H.G. Driessen, Marieke W. Veldkamp, Arie O. Verkerk, Makiri Kawasaki, Nicoline W.E. van den Berg, Isabella Mengarelli

المساهمون: Cardiology, ACS - Heart failure & arrhythmias, Graduate School, Cardiothoracic Surgery, ACS - Pulmonary hypertension & thrombosis, Medical Biology, ACS - Amsterdam Cardiovascular Sciences, APH - Methodology

المصدر: Cardiovascular Drugs and Therapy
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy, 33(6), 649-660. Kluwer Academic Publishers

مصطلحات موضوعية: Male, 0301 basic medicine, Action Potentials, SCN10A/Na 1.8, 030204 cardiovascular system & hematology, 0302 clinical medicine, Left atrial, Atrial Fibrillation, Medicine, Myocytes, Cardiac, Pharmacology (medical), health care economics and organizations, Cardiomyocytes, Voltage-Gated Sodium Channel Blockers, Membrane potential, Sodium channel, Cardiac electrophysiology, General Medicine, cardiovascular system, Cardiology, SCN10A/Nav1.8, Action potential duration, Original Article, Rabbits, Electrophysiologic Techniques, Cardiac, Cardiology and Cardiovascular Medicine, medicine.medical_specialty, Cell type, Heart Ventricles, Induced Pluripotent Stem Cells, Cell Line, Sodium current, NAV1.8 Voltage-Gated Sodium Channel, 03 medical and health sciences, Species Specificity, health services administration, Late sodium current, Internal medicine, Animals, Humans, Atrial Appendage, Heart Atria, Pharmacology, hiPSC-CMs, business.industry, Atrial tissue, Kinetics, 030104 developmental biology, NAV1, business, Patch-clamp

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7b4ef2ce4fb577a5fa2c0e1f680be0cTest
https://doi.org/10.1007/s10557-019-06925-6Test

المؤلفون: Mischa Klerk, Calum A. MacRae, Marta Pérez-Hernández, Elisabeth M. Lodder, Paul W. Burridge, Christiaan C. Veerman, Isabella Mengarelli, Richard Redon, Vincent Portero, Gerard A Marchal, Carol Ann Remme, Mario Delmar, Franck Potet, Flavien Charpentier, Kaomei Guan, Svitlana Podliesna, Nuo Yu, Carlos G. Vanoye, Alfred Lewis George, David Y. Chiang, Niels Galjart, Simona Casini, Mariam Jouni, Arie O. Verkerk, Eli Rothenberg, Connie R. Bezzina

المساهمون: Cardiology, Graduate School, ACS - Heart failure & arrhythmias, Human Genetics, Medical Biology, APH - Methodology, Cell biology

المصدر: Circ Res
Circulation research, 129(3), 349-365. Lippincott Williams and Wilkins
Circulation Research, 129(3), 349-365. Lippincott Williams & Wilkins

مصطلحات موضوعية: biology, Physiology, Chemistry, cardiac, Sodium channel, Myocardium, Fluorescence recovery after photobleaching, Nav1.5, biology.organism_classification, electrophysiology, zebrafish, Article, Sodium Channels, Cell biology, Microtubule, Cytoplasm, GSK-3, biology.protein, microscopy, Cardiology and Cardiovascular Medicine, Induced pluripotent stem cell, Zebrafish, myocyte, cardiac, myocyte, microtubule

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4ec730de2a7e331c928f42d1d495887Test
https://europepmc.org/articles/PMC8298292Test/

المؤلفون: Leander Beekman, Carol Ann Remme, Vincent Portero, Gerard A Marchal, Rafik Tadros, Arie O. Verkerk, A Blease, Paul Potter, I. Jane Cox, Svitlana Podliesna, Simona Casini, Gabi Kastenmüller, Christian Gieger, T Nicol, Tertius Hough, Moritz F. Sinner, Stefan Kääb, Annette Peters, Connie R. Bezzina, Martina Müller-Nurasyid, Michael W.T. Tanck, Sara Falcone, Jorien L. Treur, Antonius Baartscheer, Fay Probert

المساهمون: Epidemiology and Data Science, APH - Methodology, Physiology, Cardiology, ACS - Heart failure & arrhythmias, Graduate School, Adult Psychiatry, ANS - Amsterdam Neuroscience, ACS - Amsterdam Cardiovascular Sciences, Medical Biology

المصدر: Cardiovascular Research, 118(7), 1742-1757. Oxford University Press
Cardiovasc. Res. 118:1742–1757 (2021)
Cardiovascular research, 118(7), 1742-1757. Oxford University Press
Portero, V, Nicol, T, Podliesna, S, Marchal, G A, Baartscheer, A, Casini, S, Tadros, R, Treur, J L, Tanck, M W T, Jane Cox, I J, Probert, F, Hough, T A, Falcone, S, Beekman, L, Müller-Nurasyid, M, Kastenmüller, G, Gieger, C, Peters, A, Kääb, S, Sinner, M F, Blease, A, Verkerk, A O, Bezzina, C R, Potter, P K & Remme, C A 2022, ' Chronically elevated branched chain amino acid levels are pro-arrhythmic ', Cardiovascular Research, vol. 118, no. 7, pp. 1742-1757 . https://doi.org/10.1093/cvr/cvab207Test

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Physiology, Branched-chain amino acid, 030204 cardiovascular system & hematology, Sudden death, Sudden cardiac death, Afterdepolarization, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Physiology (medical), Internal medicine, Cardiac conduction, medicine, Animals, Humans, Myocytes, Cardiac, BCAA, Arrhythmia, Bcaa, Electrophysiology, Metabolism, Sudden Death, Heart Failure, Sirolimus, business.industry, Cardiac arrhythmia, medicine.disease, 030104 developmental biology, Endocrinology, chemistry, Heart failure, Calcium, Metabolic syndrome, Cardiology and Cardiovascular Medicine, business, Amino Acids, Branched-Chain

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::751f09554e89397bd6ba435a96e8ba26Test
https://pubmed.ncbi.nlm.nih.gov/34142125Test

المؤلفون: Frits A. Wijburg, Connie R. Bezzina, Suzan J. G. Knottnerus, Xiaojing Luo, Antonius Baartscheer, Kaomei Guan, Wener Li, Sacha Ferdinandusse, Ronald J.A. Wanders, Ying Ulbricht, Rob C. I. Wüst, Riekelt H. Houtkooper, Isabella Mengarelli, Gepke Visser, Ruben Coronel, Vincent Portero, Jeannette C. Bleeker, Lodewijk IJlst, Arie O. Verkerk

المساهمون: Graduate School, Laboratory Genetic Metabolic Diseases, AGEM - Endocrinology, metabolism and nutrition, AGEM - Inborn errors of metabolism, Cardiology, ACS - Heart failure & arrhythmias, ACS - Diabetes & metabolism, AMS - Ageing & Morbidty, Laboratory for General Clinical Chemistry, Paediatric Metabolic Diseases, Medical Biology, ACS - Amsterdam Cardiovascular Sciences, ARD - Amsterdam Reproduction and Development, APH - Methodology, APH - Aging & Later Life

المصدر: International journal of molecular sciences, 21(7):2589. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences, Vol 21, Iss 2589, p 2589 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 7

مصطلحات موضوعية: 0301 basic medicine, Mitochondrial Diseases, Action Potentials, 030204 cardiovascular system & hematology, Resveratrol, Mitochondrion, Arrhythmias, hiPSC, lcsh:Chemistry, chemistry.chemical_compound, 0302 clinical medicine, Congenital Bone Marrow Failure Syndromes, Myocytes, Cardiac, Induced pluripotent stem cell, Beta oxidation, lcsh:QH301-705.5, Spectroscopy, health care economics and organizations, chemistry.chemical_classification, Chemistry, Acyl-CoA Dehydrogenase, Long-Chain, Fatty Acids, General Medicine, Computer Science Applications, Mitochondria, VLCADD, Oxidation-Reduction, Intracellular, Acylcarnitines, medicine.medical_specialty, Induced Pluripotent Stem Cells, Catalysis, Lipid Metabolism, Inborn Errors, Article, Inorganic Chemistry, 03 medical and health sciences, Muscular Diseases, Internal medicine, medicine, Humans, Physical and Theoretical Chemistry, Molecular Biology, Organic Chemistry, Fatty acid, Arrhythmias, Cardiac, 030104 developmental biology, Endocrinology, lcsh:Biology (General), lcsh:QD1-999, Epoxy Compounds, Cardiac Electrophysiology, Biogenesis, Etomoxir

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1048994c1c7de653958d78caa5e5c907Test
https://pure.amc.nl/en/publications/electrophysiological-abnormalities-in-vlcad-deficient-hipsccardiomyocytes-can-be-improved-by-lowering-accumulation-of-fatty-acid-oxidation-intermediatesTest(7408927f-4407-47ac-bfe0-fd5a7be0c915).html