المؤلفون: Panagiotis Antoniou, Giulia Hardouin, Pierre Martinucci, Giacomo Frati, Tristan Felix, Anne Chalumeau, Letizia Fontana, Jeanne Martin, Cecile Masson, Megane Brusson, Giulia Maule, Marion Rosello, Carine Giovannangeli, Vincent Abramowski, Jean-Pierre de Villartay, Jean-Paul Concordet, Filippo Del Bene, Wassim El Nemer, Mario Amendola, Marina Cavazzana, Anna Cereseto, Oriana Romano, Annarita Miccio

المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2041-1723Test

الوصول الحر: https://doaj.org/article/313aa0fc4a794f6798f4ea808d498494Test

المؤلفون: Benoit Roch, Vincent Abramowski, Olivier Etienne, Stefania Musilli, Pierre David, Jean-Baptiste Charbonnier, Isabelle Callebaut, François D Boussin, Jean-Pierre de Villartay

المصدر: eLife, Vol 10 (2021)

مصطلحات موضوعية: adaptive immune system, non homologous end joining, v(d)j recombination, brain development, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

العلاقة: https://elifesciences.org/articles/69353Test; https://doaj.org/toc/2050-084XTest

الوصول الحر: https://doaj.org/article/9f2b7f8042e7416dbee800b5e8f5606bTest

المؤلفون: Benoit Roch, Vincent Abramowski, Julie Chaumeil, Jean-Pierre de Villartay

المصدر: Frontiers in Immunology, Vol 10 (2019)

مصطلحات موضوعية: lymphoid development, V(D)J recombination, positive selection, DNA repair, TCR repertoire, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/article/10.3389/fimmu.2019.00443/fullTest; https://doaj.org/toc/1664-3224Test

الوصول الحر: https://doaj.org/article/69933967aaa446038fc4b5f7cd6f86d5Test

المؤلفون: Chloé Lescale, Vincent Abramowski, Marie Bedora-Faure, Valentine Murigneux, Gabriella Vera, David B. Roth, Patrick Revy, Jean-Pierre de Villartay, Ludovic Deriano

المصدر: Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/2041-1723Test

الوصول الحر: https://doaj.org/article/45b3d85d8e094ec8ba4c1f14631de376Test

المؤلفون: Olivier Etienne, Pierre David, François D. Boussin, Jean-Pierre de Villartay, Vincent Abramowski, Isabelle Callebaut, Jean-Baptiste Charbonnier, Benoit Roch, Stefania Musilli

المساهمون: Imagine - Institut des maladies génétiques (IHU) (Imagine - U1163), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP), Equipe labellisée Ligue contre le Cancer, Stabilité génétique, cellules souches et radiations (SGCSR (U_1274 / UMR_E_008)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay-Université de Paris (UP), Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut de minéralogie, de physique des matériaux et de cosmochimie (IMPMC), Muséum national d'Histoire naturelle (MNHN)-Institut de recherche pour le développement [IRD] : UR206-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay-Université Paris Cité (UPCité), Gestionnaire, HAL Sorbonne Université 5

المصدر: eLife
eLife, eLife Sciences Publication, 2021, 10, ⟨10.7554/eLife.69353⟩
eLife, 2021, 10, ⟨10.7554/eLife.69353⟩
eLife, Vol 10 (2021)

مصطلحات موضوعية: DNA End-Joining Repair, Mouse, Mutant, brain development, Apoptosis, Ataxia Telangiectasia Mutated Proteins, DNA Ligase ATP, Lymphocytes, Biology (General), chemistry.chemical_classification, Mice, Knockout, Neurons, 0303 health sciences, General Neuroscience, 030302 biochemistry & molecular biology, V(D)J recombination, Brain, General Medicine, DNA repair protein XRCC4, Acquired immune system, Chromosomes and Gene Expression, Cell biology, Non-homologous end joining, DNA-Binding Proteins, Phenotype, Medicine, Research Article, QH301-705.5, DNA repair, Science, Mutation, Missense, [SDV.CAN]Life Sciences [q-bio]/Cancer, Biology, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, [SDV.CAN] Life Sciences [q-bio]/Cancer, adaptive immune system, Animals, Humans, Genetic Predisposition to Disease, 030304 developmental biology, Phenocopy, DNA ligase, General Immunology and Microbiology, V(D)J Recombination, Mice, Inbred C57BL, Disease Models, Animal, chemistry, Severe Combined Immunodeficiency, non homologous end joining, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82a7b9744b3b16c77e97e5abbf202b86Test
https://hal.sorbonne-universite.fr/hal-03382401/file/elife-69353-v2.pdfTest

المؤلفون: Jean-Pierre de Villartay, Isabelle Callebaut, François D. Boussin, Olivier Etienne, Vincent Abramowski, Jean-Baptiste Charbonnier, Benoit Roch, Pierre David, Stefania Musilli

مصطلحات موضوعية: Mutant, DNA repair protein XRCC4, Biology, Cell biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::09a938e0c95b106626594d783a1163b3Test
https://doi.org/10.7554/elife.69353.sa2Test

المؤلفون: Vincent Abramowski, Stefania Musilli, Benoit Roch, Jean-Pierre de Villartay

المساهمون: Imagine - Institut des maladies génétiques (IMAGINE - U1163), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM)

المصدر: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2020, pp.jbc.AC119.010924. ⟨10.1074/jbc.AC119.010924⟩
J Biol Chem

مصطلحات موضوعية: 0301 basic medicine, double-strand break, DNA repair, [SDV]Life Sciences [q-bio], lymphoma, Biology, lymphocyte, Biochemistry, Immunoglobulin Class Switch Recombination, gene knockout, immunology, 03 medical and health sciences, Bone Marrow, Animals, genetics, Lymphocytes, Molecular Biology, Gene knockout, Mice, Knockout, 030102 biochemistry & molecular biology, V(D)J recombination, Cell Biology, DNA repair protein XRCC4, Hematopoietic Stem Cells, Acquired immune system, Immunoglobulin Class Switching, Survival Analysis, Cell biology, DNA-Binding Proteins, Mice, Inbred C57BL, Non-homologous end joining, immunogenetics, 030104 developmental biology, Immunoglobulin class switching, Accelerated Communications, Immunoglobulin class switch recombination

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e47a80cdb25a69d916803c4aec20053Test
https://www.hal.inserm.fr/inserm-02481526/file/2020_PAXX-XLF_JBCproof.pdfTest

المؤلفون: Mesothelioma Cells, Tamara Utermark, M. Sc, Holger Lerche, Vincent Abramowski, Clemens Oliver Hanemann, Ulm Ulm Germany

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://www.mh-hannover.de/fileadmin/institute/neurophysiologie/Cancer2003.pdfTest.

وصف الملف: application/pdf

العلاقة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.324.8969Test; http://www.mh-hannover.de/fileadmin/institute/neurophysiologie/Cancer2003.pdfTest

الإتاحة: http://www.mh-hannover.de/fileadmin/institute/neurophysiologie/Cancer2003.pdfTest

المؤلفون: Benoit, Roch, Vincent, Abramowski, Julie, Chaumeil, Jean-Pierre, de Villartay

المصدر: Frontiers in Immunology

مصطلحات موضوعية: Mice, Knockout, B-Lymphocytes, lymphoid development, T-Lymphocytes, Immunology, DNA repair, V(D)J recombination, DNA-Binding Proteins, Mice, TCR repertoire, positive selection, Animals, Tumor Suppressor Protein p53, Gene Rearrangement, alpha-Chain T-Cell Antigen Receptor, Signal Transduction, Original Research

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::1da98be07e12d757437dae47028a852bTest
https://pubmed.ncbi.nlm.nih.gov/30923523Test

المؤلفون: Ana Cumano, Benoit Roch, Laetitia Kermasson, Ramy Elsaid, Vincent Abramowski, Jean-Paul Moussu, Olivier Etienne, Aurélie Berland, Jean-Pierre de Villartay, Stefania Musilli, Patrick Revy, Junjie Yang, François D. Boussin, Karelia Lipson-Ruffert

المساهمون: Imagine - Institut des maladies génétiques (IMAGINE - U1163), Université Paris Descartes - Paris 5 (UPD5)-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire de Radiopathologie (LRP), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Lymphopoïèse (Lymphopoïèse (UMR_1223 / U1223 / U-Pasteur_4)), Institut Pasteur [Paris] (IP)-Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM), Cellule Pasteur, Université Paris Diderot - Paris 7 (UPD7)-PRES Sorbonne Paris Cité, Transgenèse et archivage d'animaux modèles (TAAM), Centre National de la Recherche Scientifique (CNRS), This work was supported by institutional grants from INSERM, the Institut National du Cancer (PLBIO16-280), the Agence Nationale de la Recherche ('Investissement d’Avenir' program ANR-10-IAHU-01), and by grants from La Ligue Nationale contre le Cancer (Equipe Labellisée LA LIGUE), Pasteur Institute, ANR (Program REVIVE and grant Twothyme) to AC., We thank Catherine Cailleau (SEAT) for exceptional care of our mouse lines, Sophie Berissi for help in immunohistochemistry and Olivier Alibeu, Aurore Pouliet, and Christine Bole-Feyssot (Genomic facility, Imagine Institute) for their assistance in NGS, ANR-10-LABX-0073,REVIVE,Stem Cells in Regenerative Biology and Medicine(2010), ANR-14-CE11-0022,Twothyme,Deux progéniteurs hématopoïétiques différents établissent le compartiment de lymphocytes T: tester un nouveau paradigme du développement T.(2014), ANR-10-IAHU-0001,Imagine,Institut Hospitalo-Universitaire Imagine(2010), Vougny, Marie-Christine, Laboratoires d'excellence - Stem Cells in Regenerative Biology and Medicine - - REVIVE2010 - ANR-10-LABX-0073 - LABX - VALID, Appel à projets générique - Deux progéniteurs hématopoïétiques différents établissent le compartiment de lymphocytes T: tester un nouveau paradigme du développement T. - - Twothyme2014 - ANR-14-CE11-0022 - Appel à projets générique - VALID, Instituts Hospitalo-Universitaires - Institut Hospitalo-Universitaire Imagine - - Imagine2010 - ANR-10-IAHU-0001 - IAHU - VALID, Université Paris Diderot - Paris 7 (UPD7)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Pasteur [Paris]-Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM)

المصدر: Cell Death and Differentiation
Cell Death and Differentiation, 2018, 25 (2), pp.444-452. ⟨10.1038/cdd.2017.184⟩
Cell Death and Differentiation, Nature Publishing Group, 2018, 25 (2), pp.444-452. ⟨10.1038/cdd.2017.184⟩

مصطلحات موضوعية: 0301 basic medicine, Central Nervous System, DNA End-Joining Repair, [SDV.IMM] Life Sciences [q-bio]/Immunology, Biology, medicine.disease_cause, 03 medical and health sciences, Mice, Immune system, medicine, Animals, Lymphocytes, Molecular Biology, Immunodeficiency, Loss function, chemistry.chemical_classification, Mice, Knockout, DNA ligase, Mutation, Original Paper, Genetic interaction, Immunologic Deficiency Syndromes, Cell Biology, DNA repair protein XRCC4, medicine.disease, Acquired immune system, Phenotype, Cell biology, Resin Cements, DNA-Binding Proteins, Mice, Inbred C57BL, 030104 developmental biology, chemistry, Immunology, [SDV.IMM]Life Sciences [q-bio]/Immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e3cc9d04ecd1382b0369f5c36141e99Test
https://europepmc.org/articles/PMC5762856Test/