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1
المؤلفون: Shiying Chen, Wensheng Yu, Joseph A. Kozlowski, Daniel Lundell, Seong Heon Kim, Ling Tong, Shelby Umland, Xiaoda Niu, Vinay Girijavallabhan, Lei Chen, Aneta Kosinski, Guowei Zhou, Mengwei Hu, Neng-Yang Shih, Bandarpalle B. Shankar, De-Yi Yang
المصدر: Bioorganic & Medicinal Chemistry Letters. 27:3704-3708
مصطلحات موضوعية: 0301 basic medicine, Clinical Biochemistry, Administration, Oral, Pharmaceutical Science, Hydantoin, ADAM17 Protein, Pharmacology, Biochemistry, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Dogs, Drug Discovery, Animals, Humans, Potency, Prodrugs, Pentanoic Acids, Molecular Biology, Whole blood, chemistry.chemical_classification, Hydantoins, Organic Chemistry, Haplorhini, Prodrug, Tace inhibitor, Rats, Enzyme Activation, 030104 developmental biology, Enzyme, ROC Curve, chemistry, Area Under Curve, Molecular Medicine, Lead compound, Half-Life
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5125137f478242040971d76ea3dc87f8Test
https://doi.org/10.1016/j.bmcl.2017.07.007Test -
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المؤلفون: Yuhua Huang, Ian W. Davies, Paul Tawa, Stephane L. Bogen, Alexei V. Buevich, Angela Kerekes, Vinay Girijavallabhan, Hsueh-Cheng Huang, Frank Bennett
المصدر: Tetrahedron Letters. 72:153066
مصطلحات موضوعية: 010405 organic chemistry, Stereochemistry, viruses, Hepatitis C virus, Organic Chemistry, Guanosine, 010402 general chemistry, medicine.disease_cause, 01 natural sciences, Biochemistry, Ns5b polymerase, Uridine, 0104 chemical sciences, chemistry.chemical_compound, chemistry, Intramolecular force, Drug Discovery, medicine
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::632f52f143d804eb97cf5e570dfa2ca1Test
https://doi.org/10.1016/j.tetlet.2021.153066Test -
3دورية أكاديمية
المؤلفون: François Malouin, Noormohamed Niyaz, Pingyu Ding, Marvin J. Miller, Geneviève Bernier, Vinay Girijavallabhan, Aaron Murray
المساهمون: The Pennsylvania State University CiteSeerX Archives
وصف الملف: application/pdf
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المؤلفون: Guowei Zhou, Liping Yang, Neng-Yang Shih, M. Arshad Siddiqui, Vinay Girijavallabhan, Shiying Chen, Lei Chen, Dansu Li, Peter Orth, Zhuyan Guo, Bandarpalle B. Shankar, Kristin E. Rosner, Wensheng Yu, Ling Tong, Chaoyang Dai, Joseph A. Kozlowski, Aneta Kosinski, Xiaoda Niu, Seong Heon Kim, Daniel Lundell, Shelby Umland, Janeta Popovici-Muller
المصدر: Bioorganic & Medicinal Chemistry Letters. 27:3037-3042
مصطلحات موضوعية: 0301 basic medicine, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Hydantoin, ADAM17 Protein, Biochemistry, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Dogs, 0302 clinical medicine, Drug Discovery, Animals, Humans, Potency, Protease Inhibitors, Molecular Biology, Whole blood, chemistry.chemical_classification, Chemistry, Hydantoins, Organic Chemistry, Haplorhini, Rats, Enzyme Activation, 030104 developmental biology, Enzyme, ROC Curve, Area Under Curve, Molecular Medicine, Tumor necrosis factor alpha, Half-Life, 030215 immunology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e9ae78bb60384e5c554a062fa84b16eTest
https://doi.org/10.1016/j.bmcl.2017.05.062Test -
5
المؤلفون: Ruijun Sun, David B. Olsen, Peter T. Meinke, Yunfeng Bai, Zhibo Zhang, Stephane L. Bogen, Vinay Girijavallabhan, Tongqian Chen, Jie Yin, Qun Dang
المصدر: Tetrahedron Letters. 55:5576-5579
مصطلحات موضوعية: Purine, Stereochemistry, Hepatitis C virus, Organic Chemistry, Prodrug, medicine.disease_cause, Biochemistry, Ns5b polymerase, chemistry.chemical_compound, chemistry, Yield (chemistry), Drug Discovery, Lactam, medicine, Moiety, Nucleoside
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::729ad0fb26be132e167b094c1e4af45dTest
https://doi.org/10.1016/j.tetlet.2014.08.072Test -
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المؤلفون: Qun Dang, Vinay Girijavallabhan, Peter T. Meinke, David B. Olsen, Shuangsheng He, Yang Song, Tongqian Chen, Zhibo Zhang, Xinglin He, Stephane L. Bogen, Bing-Yu Tang
المصدر: Tetrahedron Letters. 55:5092-5095
مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Stereochemistry, Organic Chemistry, Drug Discovery, Ribose, Aldol condensation, C nucleosides, Ribonucleoside, Biochemistry, Nucleoside
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::f24e1d18bedfa9fc47cb36bb0fa8edc2Test
https://doi.org/10.1016/j.tetlet.2014.07.037Test -
7
المؤلفون: Yuhua Huang, Wang Lingyan, Ann E. Weber, Ian W. Davies, Hsueh-Cheng Huang, Mary Senior, Frank Bennett, Quang T. Truong, Stephane L. Bogen, Asra Malikzay, Rebecca Osterman, Eric Ferrari, Paul Tawa, Elizabeth Smith, Haiyan Pu, Vinay Girijavallabhan, Angela Kerekes, Jun Wang, Alexei V. Buevich
المصدر: Bioorganicmedicinal chemistry letters. 27(23)
مصطلحات موضوعية: 0301 basic medicine, Sofosbuvir, Stereochemistry, Propynyl, 030106 microbiology, Clinical Biochemistry, Molecular Conformation, Pharmaceutical Science, Hepacivirus, Microbial Sensitivity Tests, Viral Nonstructural Proteins, Biochemistry, Antiviral Agents, Ns5b polymerase, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, Column chromatography, Drug Discovery, medicine, Potency, Nucleotide, Molecular Biology, Uridine, chemistry.chemical_classification, 030102 biochemistry & molecular biology, Dose-Response Relationship, Drug, Organic Chemistry, Nucleosides, chemistry, Molecular Medicine, Nucleoside, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37e4b5ff6ec093c3be10484d16116faeTest
https://pubmed.ncbi.nlm.nih.gov/29056248Test -
8
المؤلفون: Yang Song, Peter T. Meinke, Vinay Girijavallabhan, Qun Dang, Ling Wu, Bing-Yu Tang, Stephane L. Bogen, Zhibo Zhang, David B. Olsen, Tongqian Chen
المصدر: Tetrahedron Letters. 55:3813-3816
مصطلحات موضوعية: Nucleoside analogue, Stereochemistry, Chemistry, Hepatitis C virus, Organic Chemistry, Epoxide, Cytidine, Prodrug, medicine.disease_cause, Biochemistry, Uridine, Ns5b polymerase, chemistry.chemical_compound, Drug Discovery, medicine, Nucleoside, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::b909d55be891d0936f95d1dd7235bdbeTest
https://doi.org/10.1016/j.tetlet.2014.05.051Test -
9
المؤلفون: Jeremy Clark, Xiao Tong, Ashok Arasappan, Randall R. Rossman, Anita T. Fowler, Subramaniam Ananthan, Vinay Girijavallabhan, Feng Geng, Regina Huelgas, Neng-Yang Shih, F. George Njoroge, Hollis S. Kezar, Joseph A. Maddry, Yuhua Huang, Frank Bennett, Cheng Li, John J. Piwinski, Cecil D. Kwong, John A. Secrist, Stephanie Curry, Abhijit Roychowdhury, Malcolm MacCoss, Robert C. Reynolds, Hsueh-Cheng Huang, Robert Chase
المصدر: Bioorganic & Medicinal Chemistry Letters. 22:5144-5149
مصطلحات موضوعية: Pyrimidine, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Hepacivirus, Virus Replication, Antiviral Agents, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Pyridine, Animals, Moiety, Replicon, Enzyme Inhibitors, Benzofuran, Furans, Molecular Biology, Benzofurans, Organic Chemistry, Pyrimidine Nucleosides, RNA-Dependent RNA Polymerase, Rats, Pyrimidines, Liver, chemistry, Alkoxy group, Molecular Medicine, Selectivity, Half-Life, Methyl group
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a19a20c57978b9eb8444e2b3affa03ceTest
https://doi.org/10.1016/j.bmcl.2012.06.021Test -
10
المؤلفون: Jun Wang, Weidong Pan, F. George Njoroge, Vinay Girijavallabhan, Ying Huang, Ping Chen, Latha G. Nair, Frank Bennett, Angela Kerekes, Ashok Arasappan, Qun Dang, Qingmei Hong, Stephane L. Bogen, Zhidan Liu, Quang Truong, Sara Esposite, Yuhua Huang, Bancha Vibulbhan, Haiyan Pu, Andrew Stamford, Dmitri A. Pissarnitski, Kevin X. Chen, David B. Olsen, Vishal Verma, David Cole, Zhiqiang Zhao, Randall R. Rossman, Alvarez Carmen S
المصدر: Nucleosides, nucleotidesnucleic acids. 35(6)
مصطلحات موضوعية: Olefin fiber, Azides, 010405 organic chemistry, Guanosine, General Medicine, Hepacivirus, Alkenes, Viral Nonstructural Proteins, 010402 general chemistry, Bioinformatics, 01 natural sciences, Biochemistry, Combinatorial chemistry, Antiviral Agents, Ns5b polymerase, Guanine Nucleotides, 0104 chemical sciences, chemistry.chemical_compound, chemistry, Genetics, Hydrocyanation, Molecular Medicine, Nucleic Acid Synthesis Inhibitors
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5a12e0b1f99db43b830f93b2c1a155dTest
https://pubmed.ncbi.nlm.nih.gov/27104963Test