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1دورية أكاديمية
المؤلفون: Villars, Alexis, Letort, Gaëlle, Valon, Léo, Levayer, Romain
المساهمون: Biologie du Développement et Cellules souches (CNRS UMR3738), Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Ecole Doctorale Complexité du Vivant (ED515), Sorbonne Université (SU), A.V. was supported by a PhD grant from the doctoral school ‘Complexité du Vivant’ Sorbonne Université and from an extension grant of the Ligue Contre le Cancer. Work in the R.L. lab is supported by the Institut Pasteur (G5 starting package), a European Research Council starting grant (CoSpaDD, Competition for Space in Development and Disease, grant number 758457), the Agence Nationale de la Recherche (CoECECa, Coordination of Epithelial Cell Extrusion by Caspases) and the Centre National de la Recherche Scientifique (UMR 3738). We also thank Danielle Casteran and her family for their generous donation, which helped to finalise this project. Open Access funding provided by the European Research Council. Deposited in PMC for immediate release., We acknowledge the Image Analysis Hub of the Institut Pasteur for discussions and advice for this work. We thank Jean-Yves Tinevez, Kevin Yamauchi and Raphaël Etournay for critical reading of the manuscript. We also thank Raphaël Etournay for sharing the pupal wing movie and Nic Tapon for providing the original and segmentation of the pupal abdomen movies. We acknowledge the help of the HPC Core Facility of the Institut Pasteur for this work., ANR-22-CE13-0002,CoECECa,Vers une caractérisation exhaustive de la coordination de l'extrusion epithéliales par les caspases(2022), European Project: 758457,H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC),ERC-2017-STG,CoSpaDD(2018)
المصدر: ISSN: 0950-1991.
مصطلحات موضوعية: Deep-learning, convolutional neural network, epithelia, live imaging, extrusion, cell division, SOPs, Drosophila, [SDV.BC.IC]Life Sciences [q-bio]/Cellular Biology/Cell Behavior [q-bio.CB]
العلاقة: info:eu-repo/semantics/altIdentifier/pmid/37283069; info:eu-repo/grantAgreement//758457/EU/Competition for Space in Development and Diseases/CoSpaDD; pasteur-04244427; https://pasteur.hal.science/pasteur-04244427Test; https://pasteur.hal.science/pasteur-04244427/documentTest; https://pasteur.hal.science/pasteur-04244427/fileTest/Villars%26LetortFused.pdf; PUBMED: 37283069; PUBMEDCENTRAL: PMC10323232
الإتاحة: https://doi.org/10.1242/dev.201747Test
https://pasteur.hal.science/pasteur-04244427Test
https://pasteur.hal.science/pasteur-04244427/documentTest
https://pasteur.hal.science/pasteur-04244427/fileTest/Villars%26LetortFused.pdf -
2دورية أكاديمية
مصطلحات موضوعية: cell extrusion, cell death, apoptosis, developmental biology, morphogenesis
العلاقة: https://zenodo.org/record/6546831Test; https://doi.org/10.5281/zenodo.6546831Test; oai:zenodo.org:6546831
الإتاحة: https://doi.org/10.5281/zenodo.6546831Test
https://doi.org/10.5281/zenodo.6546830Test
https://zenodo.org/record/6546831Test -
3دورية أكاديمية
المؤلفون: Villars, Alexis, Levayer, Romain
المساهمون: Ecole Doctorale Complexité du Vivant (ED515), Sorbonne Université (SU), Mort cellulaire et homéostasie des épithéliums / Cell death and epithelial homeostasis, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), AV is supported by a PhD grant from the Ecole Doctorale Complexité du Vivant (Sorbonne University) and from an extension grant of La Ligue contre le Cancer (IP/SC-17130), work in RL lab is supported by the Institut Pasteur (G5 starting package), the ERC starting grant CoSpaDD (Competition for Space in Development and Disease, grant number 758457), the Cercle FSER and the CNRS (UMR 3738)., European Project: 758457,H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC),ERC-2017-STG,CoSpaDD(2018)
المصدر: ISSN: 0959-437X.
مصطلحات موضوعية: epithelium, apoptosis, extrusion, self-organisation, [SDV]Life Sciences [q-bio], [SDV.BC]Life Sciences [q-bio]/Cellular Biology
العلاقة: info:eu-repo/semantics/altIdentifier/pmid/34626896; info:eu-repo/grantAgreement//758457/EU/Competition for Space in Development and Diseases/CoSpaDD; hal-03651098; https://hal.science/hal-03651098Test; https://hal.science/hal-03651098/documentTest; https://hal.science/hal-03651098/file/Villaurs%26Levayer2021.pdfTest; PUBMED: 34626896
الإتاحة: https://doi.org/10.1016/j.gde.2021.09.004Test
https://hal.science/hal-03651098Test
https://hal.science/hal-03651098/documentTest
https://hal.science/hal-03651098/file/Villaurs%26Levayer2021.pdfTest -
4دورية أكاديمية
المصدر: Nature Communications ; volume 13, issue 1 ; ISSN 2041-1723
مصطلحات موضوعية: General Physics and Astronomy, General Biochemistry, Genetics and Molecular Biology, General Chemistry, Multidisciplinary
الإتاحة: https://doi.org/10.1038/s41467-022-32068-8Test
https://www.nature.com/articles/s41467-022-32068-8.pdfTest
https://www.nature.com/articles/s41467-022-32068-8Test -
5دورية أكاديمية
المصدر: Nature Communications ; volume 13, issue 1 ; ISSN 2041-1723
مصطلحات موضوعية: General Physics and Astronomy, General Biochemistry, Genetics and Molecular Biology, General Chemistry, Multidisciplinary
الإتاحة: https://doi.org/10.1038/s41467-022-31266-8Test
https://www.nature.com/articles/s41467-022-31266-8.pdfTest
https://www.nature.com/articles/s41467-022-31266-8Test -
6تقرير
المساهمون: Mort cellulaire et homéostasie des épithéliums / Cell death and epithelial homeostasis, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Ecole Doctorale Complexité du Vivant (ED515), Sorbonne Université (SU), AV is supported by a PhD grant from the doctoral school “Complexité du Vivant” Sorbonne Université and from an extension grant of La Ligue contre le Cancer, work in RL lab is supported by the Institut Pasteur (G5 starting package), the ERC starting grant CoSpaDD (Competition for Space in Development and Disease, grant number 758457), the Cercle FSER and the CNRS (UMR 3738)., European Project: 758457,H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC),ERC-2017-STG,CoSpaDD(2018)
المصدر: https://hal.science/hal-03651112Test ; 2022.
مصطلحات موضوعية: [SDV]Life Sciences [q-bio]
العلاقة: info:eu-repo/grantAgreement//758457/EU/Competition for Space in Development and Diseases/CoSpaDD; hal-03651112; https://hal.science/hal-03651112Test; https://hal.science/hal-03651112/documentTest; https://hal.science/hal-03651112/file/Villarsetal2021-10-15-allfused.pdfTest; BIORXIV: 2021.10.15.464503
الإتاحة: https://doi.org/10.1101/2021.10.15.464503Test
https://hal.science/hal-03651112Test
https://hal.science/hal-03651112/documentTest
https://hal.science/hal-03651112/file/Villarsetal2021-10-15-allfused.pdfTest -
7دورية أكاديمية
المؤلفون: Valon, Léo, Davidović, Anđela, Levillayer, Florence, Villars, Alexis, Chouly, Mathilde, Cerqueira-Campos, Fabiana, Levayer, Romain
المساهمون: Cellules Souches et Développement / Stem Cells and Development, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Département de Biologie Computationnelle - Department of Computational Biology, Collège Doctoral, Sorbonne Université (SU), L.V. is supported by a postdoctoral grant “Aide au Retour en France” from the FRM (Fondation pour la Recherche Médicale, ARF20170938651) and a Marie Sklodowska-Curie postdoctoral fellowship (MechDeath, 789573), and work in R.L.’s lab is supported by the Institut Pasteur (G5 starting package), the ERC starting grant CoSpaDD (Competition for Space in Development and Disease, grant number 758457), and the Cercle FSER, and the CNRS (UMR 3738)., We thank members of R.L.’s lab for critical reading of the manuscript, especially Alexis Matamoro-Vidal for suggestions on the manuscript organization. We would like to thank Jakub Voznica for initiating observations of miniCic in the pupal abdomen during his internship and Anne Loap for her contribution to tissue segmentation and caspase dynamics analysis during her internship. We also thank Virgile Andreani for help in improving simulations, statistical analysis of the data, and some mathematical expressions. We are grateful for the image analysis center of Pasteur Institute and Jean-Yves Tinevez for converting the local-projection program to Fiji. We are also grateful to Magali Suzanne, Yohanns Bellaïche, Shigeo Hayashi, Jared Toettcher, the Bloomington Drosophila Stock Center, the Drosophila Genetic Resource Center, and the Vienna Drosophila Resource Center for sharing stocks and reagents. We also thank B. Aigouy for the Packing Analyser software and the J. Ellenberg group for MyPic autofocus macro., ANR-10-LABX-0073,REVIVE,Stem Cells in Regenerative Biology and Medicine(2010), European Project: 758457,H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC),ERC-2017-STG,CoSpaDD(2018)
المصدر: ISSN: 1534-5807 ; Developmental Cell ; https://hal.sorbonne-universite.fr/hal-03250153Test ; Developmental Cell, 2021, ⟨10.1016/j.devcel.2021.05.006⟩.
مصطلحات موضوعية: apoptosis, caspase dynamics, cell extrusion, epithelium, optogenetics, self-organization, single-cell live imaging, Drosophila, ERK, [SDV]Life Sciences [q-bio]
العلاقة: info:eu-repo/semantics/altIdentifier/pmid/34081909; info:eu-repo/grantAgreement//758457/EU/Competition for Space in Development and Diseases/CoSpaDD; hal-03250153; https://hal.sorbonne-universite.fr/hal-03250153Test; https://hal.sorbonne-universite.fr/hal-03250153v2/documentTest; https://hal.sorbonne-universite.fr/hal-03250153v2/file/1-s2.0-S1534580721004354-main.pdfTest; PUBMED: 34081909
الإتاحة: https://doi.org/10.1016/j.devcel.2021.05.006Test
https://hal.sorbonne-universite.fr/hal-03250153Test
https://hal.sorbonne-universite.fr/hal-03250153v2/documentTest
https://hal.sorbonne-universite.fr/hal-03250153v2/file/1-s2.0-S1534580721004354-main.pdfTest -
8دورية أكاديمية
المؤلفون: Villars, Alexis, Levayer, Romain
المساهمون: Epigénomique, Prolifération et Identité Cellulaire - Epigenomics, Proliferation and the Identity of Cells (EPIC), Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Collège Doctoral, Sorbonne Université (SU)
المصدر: ISSN: 0960-9822.
العلاقة: info:eu-repo/semantics/altIdentifier/pmid/32097644; hal-02644862; https://hal.science/hal-02644862Test; https://hal.science/hal-02644862/documentTest; https://hal.science/hal-02644862/file/FusedTest-Villars%26Levayer.pdf; PUBMED: 32097644
الإتاحة: https://doi.org/10.1016/j.cub.2019.12.033Test
https://hal.science/hal-02644862Test
https://hal.science/hal-02644862/documentTest
https://hal.science/hal-02644862/file/FusedTest-Villars%26Levayer.pdf -
9
المؤلفون: Villars, Alexis
المساهمون: Mort cellulaire et homéostasie des épithéliums / Cell death and epithelial homeostasis, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Sorbonne Université, Romain Levayer
المصدر: Cellular Biology. Sorbonne Université, 2022. English. ⟨NNT : 2022SORUS567⟩
مصطلحات موضوعية: Apoptose, Morphogenesis, Apoptosis, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Cell extrusion, Microtubules
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=od______2100::18d43fb37ecb426a6aba718993703a98Test
https://theses.hal.science/tel-04115881Test -
10رسالة جامعية
المؤلفون: Villars, Alexis
المساهمون: Mort cellulaire et homéostasie des épithéliums / Cell death and epithelial homeostasis, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Sorbonne Université, Romain Levayer
المصدر: https://theses.hal.science/tel-04115881Test ; Cellular Biology. Sorbonne Université, 2022. English. ⟨NNT : 2022SORUS567⟩.
مصطلحات موضوعية: Cell extrusion, Apoptosis, Microtubules, Morphogenesis, Apoptose, [SDV.BC]Life Sciences [q-bio]/Cellular Biology
العلاقة: NNT: 2022SORUS567; tel-04115881; https://theses.hal.science/tel-04115881Test; https://theses.hal.science/tel-04115881/documentTest; https://theses.hal.science/tel-04115881/file/VILLARS_Alexis_these_2022.pdfTest
