دورية أكاديمية
A comprehensive review of SARS-CoV-2 vaccines: Pfizer, Moderna & Johnson & Johnson
| العنوان: | A comprehensive review of SARS-CoV-2 vaccines: Pfizer, Moderna & Johnson & Johnson |
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| المؤلفون: | Rikin Patel, Mohamad Kaki, Venkat S. Potluri, Payal Kahar, Deepesh Khanna |
| المصدر: | Human Vaccines & Immunotherapeutics, Vol 18, Iss 1 (2022) |
| بيانات النشر: | Taylor & Francis Group, 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Immunologic diseases. Allergy LCC:Therapeutics. Pharmacology |
| مصطلحات موضوعية: | vaccine, covid-19, coronavirus, sars-cov-2, pfizer, moderna, johnson & johnson, Immunologic diseases. Allergy, RC581-607, Therapeutics. Pharmacology, RM1-950 |
| الوصف: | The novel coronavirus outbreak was declared a pandemic in March 2020. We are reviewing the COVID-19 vaccines authorized for use in the United States by discussing the mechanisms of action, administration, side effects, and efficacy of vaccines developed by Pfizer, Moderna, and Johnson & Johnson. Pfizer and Moderna developed mRNA vaccines, encoding the spike protein of SARS-CoV-2, whereas Johnson & Johnson developed an adenovirus vector-based vaccine. Safety has been shown in a large cohort of participants in clinical trials as well as the general population since emergency approval of vaccine administration in the US. Clinical trial results showed the Pfizer and Moderna vaccines to be 95.0%, and the Johnson & Johnson vaccine to be 66.0% effective in protecting against moderate and symptomatic SARS-CoV-2 infection. It is important to keep medical literature updated with the ongoing trials of these vaccinations, especially as they are tested among different age groups and upon the emergence of novel variants of the SARS-CoV-2 coronavirus. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2164-5515 2164-554X 21645515 |
| العلاقة: | https://doaj.org/toc/2164-5515Test; https://doaj.org/toc/2164-554XTest |
| DOI: | 10.1080/21645515.2021.2002083 |
| الوصول الحر: | https://doaj.org/article/d372ef24e4ce4b20938c90de1135573eTest |
| رقم الانضمام: | edsdoj.372ef24e4ce4b20938c90de1135573e |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 21645515 2164554X |
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| DOI: | 10.1080/21645515.2021.2002083 |