يعرض 1 - 10 نتائج من 39 نتيجة بحث عن '"Valeria, Napolitano"', وقت الاستعلام: 1.51s تنقيح النتائج
  1. 1
    دورية أكاديمية
    HtpG—A Major Virulence Factor and a Promising Vaccine Antigen against Mycobacterium tuberculosis

    المؤلفون: Rita Berisio, Giovanni Barra, Valeria Napolitano, Mario Privitera, Maria Romano, Flavia Squeglia, Alessia Ruggiero

    المصدر: Biomolecules, Vol 14, Iss 4, p 471 (2024)

    مصطلحات موضوعية: protein structure, tuberculosis, chaperone, folding, vaccine, Microbiology, QR1-502

    وصف الملف: electronic resource

    العلاقة: https://www.mdpi.com/2218-273X/14/4/471Test; https://doaj.org/toc/2218-273XTest

    الوصول الحر: https://doaj.org/article/54b84b47cac8459fa403ca567e8ff797Test

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  2. 2
    دورية أكاديمية
    Small molecule mediated inhibition of protein cargo recognition by peroxisomal transport receptor PEX5 is toxic to Trypanosoma

    المؤلفون: Valeria Napolitano, Charlotte A. Softley, Artur Blat, Vishal C. Kalel, Kenji Schorpp, Till Siebenmorgen, Kamyar Hadian, Ralf Erdmann, Michael Sattler, Grzegorz M. Popowicz, Grzegorz Dubin

    المصدر: Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)

    مصطلحات موضوعية: Medicine, Science

    وصف الملف: electronic resource

    العلاقة: https://doaj.org/toc/2045-2322Test

    الوصول الحر: https://doaj.org/article/ab883f4a01d442d8963c7e6b3aaf0f64Test

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  3. 3
    دورية أكاديمية
    In Silico Identification and In Vitro Evaluation of New ABCG2 Transporter Inhibitors as Potential Anticancer Agents

    المؤلفون: Simone Di Micco, Veronica DI SARNO, martina rossi, Vincenzo Vestuto, Takumi Konno, Sara Novi, Mario Felice TECCE, Valeria Napolitano, Tania CIAGLIA, Andrea Vitale, Isabel Maria Gomez Monterrey, Giuseppe Bifulco, Alessia Bertamino, Carmine Ostacolo, Paolo Blasi, Alessio Fasano, Pietro Campiglia, Simona Musella

    المساهمون: Simone Di Micco, Veronica DI SARNO, martina rossi, Vincenzo Vestuto, Takumi Konno, Sara Novi, Mario Felice TECCE, Valeria Napolitano, Tania CIAGLIA, Andrea Vitale, Isabel Maria Gomez Monterrey, Giuseppe Bifulco, Alessia Bertamino, Carmine Ostacolo, Paolo Blasi, Alessio Fasano, Pietro Campiglia, Simona Musella

    مصطلحات موضوعية: ATP-binding cassette, drug discovery, in silico studie, multicellular tumor spheroid, multidrug resistance

    وصف الملف: ELETTRONICO

    العلاقة: info:eu-repo/semantics/altIdentifier/pmid/36614168; info:eu-repo/semantics/altIdentifier/wos/WOS:000910146700001; volume:24; issue:1; firstpage:1; lastpage:19; numberofpages:19; journal:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES; https://hdl.handle.net/11585/924253Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85145969416; https://www.mdpi.com/1422-0067/24/1/725Test

    الإتاحة: https://doi.org/10.3390/ijms24010725Test
    https://hdl.handle.net/11585/924253Test
    https://www.mdpi.com/1422-0067/24/1/725Test

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  4. 4
    دورية أكاديمية
    Crystal Structure of Staphopain C from Staphylococcus aureus

    المؤلفون: Malgorzata Magoch, Alastair G. McEwen, Valeria Napolitano, Benedykt Władyka, Grzegorz Dubin

    المصدر: Molecules; Volume 28; Issue 11; Pages: 4407

    مصطلحات موضوعية: Staphylococcus aureus, staphopain, ScpA2, virulence factor, cysteine protease, X-ray crystallography

    جغرافية الموضوع: agris

    وصف الملف: application/pdf

    العلاقة: Chemical Biology; https://dx.doi.org/10.3390/molecules28114407Test

    الإتاحة: https://doi.org/10.3390/molecules28114407Test

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  5. 5
    دورية أكاديمية
    In Silico Identification and In Vitro Evaluation of New ABCG2 Transporter Inhibitors as Potential Anticancer Agents

    المؤلفون: Simone Di Micco, Veronica Di Sarno, Martina Rossi, Vincenzo Vestuto, Takumi Konno, Sara Novi, Mario Felice Tecce, Valeria Napolitano, Tania Ciaglia, Andrea Vitale, Isabel Maria Gomez-Monterrey, Giuseppe Bifulco, Alessia Bertamino, Carmine Ostacolo, Paolo Blasi, Alessio Fasano, Pietro Campiglia, Simona Musella

    المصدر: International Journal of Molecular Sciences, Vol 24, Iss 1, p 725 (2022)

    مصطلحات موضوعية: drug discovery, in silico studies, multidrug resistance, multicellular tumor spheroids, ATP-binding cassette, Biology (General), QH301-705.5, Chemistry, QD1-999

    وصف الملف: electronic resource

    العلاقة: https://www.mdpi.com/1422-0067/24/1/725Test; https://doaj.org/toc/1661-6596Test; https://doaj.org/toc/1422-0067Test

    الوصول الحر: https://doaj.org/article/ae8af490395f43178b35904fdc99127bTest

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  6. 6
    دورية أكاديمية
    Computer-Aided Design and Synthesis of a New Class of PEX14 Inhibitors: Substituted 2,3,4,5-Tetrahydrobenzo[F][1,4]oxazepines as Potential New Trypanocidal Agents

    المؤلفون: Roberto Fino (8231478), Dominik Lenhart (6060077), Vishal C. Kalel (8231472), Charlotte A. Softley (11513860), Valeria Napolitano (8231475), Ryan Byrne (11513863), Wolfgang Schliebs (170794), Maciej Dawidowski (8231469), Ralf Erdmann (170790), Michael Sattler (17373), Gisbert Schneider (17096), Oliver Plettenburg (481045), Grzegorz M. Popowicz (179378)

    مصطلحات موضوعية: Biochemistry, Pharmacology, Biotechnology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, f ][ 1, digit micromolar ic, dawidowski et al, adme testing gives, lead molecules toward, peroxisomal import matrix, future lead optimization, aided drug design, new drug active, initial compounds obtained, drug development campaign, based drug design, 50 , lead optimization, aided design, vitro <, protein import, trypanocidal activity, treat trypanosomiasis, taken forward, successfully disrupted, studies result, structural biology

    العلاقة: https://figshare.com/articles/journal_contribution/Computer-Aided_Design_and_Synthesis_of_a_New_Class_of_PEX14_Inhibitors_Substituted_2_3_4_5-Tetrahydrobenzo_F_1_4_oxazepines_as_Potential_New_Trypanocidal_Agents/16725634Test

    الإتاحة: https://doi.org/10.1021/acs.jcim.1c00472.s001Test

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  7. 7
    Structure-based design, synthesis and evaluation of a novel family of PEX5-PEX14 interaction inhibitors against Trypanosoma

    المؤلفون: Valeria Napolitano, Piotr Mróz, Monika Marciniak, Vishal C. Kalel, Charlotte A. Softley, Julian D. Janna Olmos, Bettina G. Tippler, Kenji Schorpp, Sarah Rioton, Tony Fröhlich, Oliver Plettenburg, Kamyar Hadian, Ralf Erdmann, Michael Sattler, Grzegorz M. Popowicz, Maciej Dawidowski, Grzegorz Dubin

    المصدر: Eur. J. Med. Chem. 243:114778 (2022)

    مصطلحات موضوعية: Pharmacology, Protein Transport, Trypanosoma, Structure-Activity Relationship, Organic Chemistry, Drug Discovery, Trypanosoma brucei brucei, Membrane Proteins, Chagas Disease, Glycosomal Protein Import, Hts, Human African Trypanosomiasis, Ppi Inhibition, Structure-based Drug Design, General Medicine, Microbodies, Trypanocidal Agents

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79e15a3ec07e102366e8fc4ca9cc1dcdTest
    https://pubmed.ncbi.nlm.nih.gov/36194937Test


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  8. 8
    Acriflavine, a clinically approved drug, inhibits SARS-CoV-2 and other betacoronaviruses

    المؤلفون: Valeria Napolitano, Agnieszka Dabrowska, Kenji Schorpp, André Mourão, Emilia Barreto-Duran, Malgorzata Benedyk, Pawel Botwina, Stefanie Brandner, Mark Bostock, Yuliya Chykunova, Anna Czarna, Grzegorz Dubin, Tony Fröhlich, Michael Hölscher, Malwina Jedrysik, Alex Matsuda, Katarzyna Owczarek, Magdalena Pachota, Oliver Plettenburg, Jan Potempa, Ina Rothenaigner, Florian Schlauderer, Klaudia Slysz, Artur Szczepanski, Kristin Greve-Isdahl Mohn, Bjorn Blomberg, Michael Sattler, Kamyar Hadian, Grzegorz Maria Popowicz, Krzysztof Pyrc

    المصدر: Cell Chemical Biology
    Cell chemical biology 29 (2022), Nr. 5
    Cell chemical biology
    Cell Chem. Bio. 29, 774-784.e8 (2022)

    مصطلحات موضوعية: Dewey Decimal Classification::500 | Naturwissenschaften::540 | Chemie, Dewey Decimal Classification::500 | Naturwissenschaften::570 | Biowissenschaften, Biologie, Clinical Biochemistry, coronavirus, Biochemistry, acriflavine, Antiviral Agents, Article, protease inhibitor, Mice, ddc:570, Drug Discovery, structural biology, Animals, Humans, Molecular Biology, Pandemics, Pharmacology, drug repurposing, SARS-CoV-2, COVID-19, protease, COVID-19 Drug Treatment, Molecular Docking Simulation, PLpro, Covid-19, Pl(pro), Sars-cov-2, Acriflavine, Coronavirus, Drug Repurposing, Protease, Protease Inhibitor, Structural Biology, ddc:540, Molecular Medicine

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::531edc41a740649bff0588acda8eaf23Test
    http://europepmc.org/articles/PMC8751734Test


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  9. 9
    Small molecule mediated inhibition of protein cargo recognition by peroxisomal transport receptor PEX5 is toxic to Trypanosoma

    المؤلفون: Valeria, Napolitano, Charlotte A, Softley, Artur, Blat, Vishal C, Kalel, Kenji, Schorpp, Till, Siebenmorgen, Kamyar, Hadian, Ralf, Erdmann, Michael, Sattler, Grzegorz M, Popowicz, Grzegorz, Dubin

    المصدر: Sci. Rep. 12:14705 (2022)

    مصطلحات موضوعية: Protein Transport, Trypanosoma, Multidisciplinary, Peroxisome-Targeting Signal 1 Receptor, Peroxisomes, Humans, Receptors, Cytoplasmic and Nuclear, Carrier Proteins, Microbodies, Peroxisomal Targeting Signal 2 Receptor

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2954316ccbeaa411769a876317f44d4eTest
    https://ruj.uj.edu.pl/xmlui/handle/item/305330Test


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  10. 10
    EstablishingTrypanosoma cruzifarnesyl pyrophosphate synthase as a viable target for biosensor driven fragment‐based lead discovery

    المؤلفون: U. Helena Danielson, Helena Nordström, Tom Dzus, Valeria Napolitano, Giulia Opassi, Gerhard Klebe, Arne Lundin, Francesca Magari

    المصدر: Protein Science
    Protein Science : A Publication of the Protein Society

    مصطلحات موضوعية: Chagas disease, Thermal shift assay, Trypanosoma cruzi, Fragment-based lead discovery, Farnesyl pyrophosphate, SPR, Biochemistry, Pyrophosphate, Catalysis, Article, Cofactor, 03 medical and health sciences, chemistry.chemical_compound, Magnesium, Luciferase, Molecular Biology, 030304 developmental biology, 0303 health sciences, biology, 030302 biochemistry & molecular biology, Biochemistry and Molecular Biology, Geranyltranstransferase, fragment screening, Articles, Surface Plasmon Resonance, binding efficiency, biology.organism_classification, farnesyl pyrophosphate synthase, chemistry, biology.protein, Target protein, Biokemi och molekylärbiologi

    وصف الملف: application/pdf

    الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4244925221396853671363436167464eTest
    https://doi.org/10.1002/pro.3834Test


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