المؤلفون: Pavel V Belichenko, Rime Madani, Lorianne Rey-Bellet, Maria Pihlgren, Ann Becker, Adeline Plassard, Stephanie Vuillermot, Valérie Giriens, Rachel L Nosheny, Alexander M Kleschevnikov, Janice S Valletta, Sara K S Bengtsson, Gordon R Linke, Michael T Maloney, David T Hickman, Pedro Reis, Anne Granet, Dorin Mlaki, Maria Pilar Lopez-Deber, Long Do, Nishant Singhal, Eliezer Masliah, Matthew L Pearn, Andrea Pfeifer, Andreas Muhs, William C Mobley

المصدر: PLoS ONE, Vol 11, Iss 3, p e0152471 (2016)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

العلاقة: http://europepmc.org/articles/PMC4811554?pdf=renderTest; https://doaj.org/toc/1932-6203Test

الوصول الحر: https://doaj.org/article/e6e5615e619c41a0ad64eafb049c71c7Test

المؤلفون: Emma Fiorini, Marija Vukicevic, Rakel Carpintero, Marcela Rincon, Pilar Lopez‐Deber, Nicolas Piot, Maxime Ayer, Inmaculada Rentero, Stefanie Siegert, Chiara Babolin, Delphine Knittel, Eva Gollwitzer, Sophie Bravo‐Veyrat, Valérie Giriens, Catherine Morici, Marie‐Gabrielle Beuzelin, Anthony Gesbert, Sebastien Rivot, Nathalie Chuard, Vanessa Attanasio, Saskia Delpretti, Piergiorgio Donati, Johannes Streffer, Andrea Pfeifer, Marie Kosco‐Vilbois

المصدر: Alzheimer's & Dementia. 18

مصطلحات موضوعية: Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Epidemiology, Health Policy, Neurology (clinical), Geriatrics and Gerontology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::ba6d5186632caddb85bea98d4b5881deTest
https://doi.org/10.1002/alz.065688Test

المؤلفون: Yvan Varisco, Anne Hamel, Nampally Sreenivasachary, Wolfgang Froestl, Valérie Giriens, Heiko Kroth, Pascal Benderitter, Andreas Muhs, Andrea Pfeifer, Paolo Paganetti

المصدر: Bioorganic & Medicinal Chemistry Letters. 26:3330-3335

مصطلحات موضوعية: 0301 basic medicine, Pyridines, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, 01 natural sciences, Biochemistry, Protein Aggregates, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, β amyloid, Drug Discovery, Pyridine, Humans, Structure–activity relationship, Moiety, Molecular Biology, Amyloid beta-Peptides, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Hydrogen bond, Organic Chemistry, 0104 chemical sciences, 030104 developmental biology, Molecular Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb9312584d8d514d20c50ae6f46c639fTest
https://doi.org/10.1016/j.bmcl.2016.05.040Test

المؤلفون: Andreas Muhs, Maria Pihlgren, Emma Fiorini, Andrea Pfeifer, Nathalie Chuard, Delphine Knittel, Valérie Giriens, Marija Vukicevic

المصدر: Alzheimer's & Dementia. 13

مصطلحات موضوعية: Amyloid β, Epidemiology, Health Policy, Molecular biology, Oligomer, Highly sensitive, Psychiatry and Mental health, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Specific antibody, Monomer, Developmental Neuroscience, chemistry, Neurology (clinical), Geriatrics and Gerontology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::a6b57fd7a7463d8379b00bc2646be936Test
https://doi.org/10.1016/j.jalz.2017.06.1277Test

المؤلفون: Kasia Piorkowska, Valérie Giriens, Andreas Muhs, Philippe Colin, Maria Pihlgren, Nathalie Chuard, Andrea Pfeifer, Marija Vukicevic, Valerie Gafner, Bernard L. Schneider, Sameer Nazeeruddin, Pamela Valdés

المصدر: Alzheimer's & Dementia. 12

مصطلحات موضوعية: Liposome, Epidemiology, business.industry, Health Policy, Disease, Pharmacology, Phospho tau, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Developmental Neuroscience, Medicine, Neurology (clinical), Geriatrics and Gerontology, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::7939fcf6291a8301d927aea9d4b4e9b7Test
https://doi.org/10.1016/j.jalz.2016.06.468Test

المؤلفون: Ann Becker, Lorianne Rey-Bellet, Andrea Pfeifer, Michael T. Maloney, Pavel V. Belichenko, Anne Granet, Dorin Mlaki, Valérie Giriens, Sara K. Bengtsson, David T. Hickman, Andreas Muhs, Rime Madani, Adeline Plassard, Nishant Singhal, Rachel L. Nosheny, Maria Pihlgren, Long Do, Stephanie Vuillermot, Gordon R. Linke, Matthew L. Pearn, Janice S. Valletta, William C. Mobley, Pedro Reis, María Pilar López-Deber, Alexander M. Kleschevnikov, Eliezer Masliah

المساهمون: Herault, Yann

المصدر: PLoS ONE
PloS one, vol 11, iss 3
PLoS ONE, Vol 11, Iss 3, p e0152471 (2016)

مصطلحات موضوعية: Male, Aging, medicine.medical_treatment, Alzheimer's Disease, Biochemistry, Transgenic, Mice, 0302 clinical medicine, Amyloid precursor protein, Public and Occupational Health, Aetiology, Enzyme-Linked Immunoassays, lcsh:Science, Mammals, Basal forebrain, Behavior, Animal, Vaccination, Brain, Cholinergic Neurons, 3. Good health, Blood, Neurology, Amyloid, Intellectual and Developmental Disabilities (IDD), Immunology, Hemorrhage, 03 medical and health sciences, Alzheimer Disease, Memory, Cholinergic neuron, Immunoassays, Behavior, Animal, lcsh:R, Organisms, Biology and Life Sciences, Proteins, medicine.disease, Prevention of disease and conditions, 030104 developmental biology, lcsh:Q, Dementia, Preventive Medicine, Atrophy, Down Syndrome, Cognition Disorders, 030217 neurology & neurosurgery, Biomarkers, 0301 basic medicine, and promotion of well-being, Physiology, lcsh:Medicine, Monophosphoryl Lipid A, Neurodegenerative, Immune Physiology, Medicine and Health Sciences, 2.1 Biological and endogenous factors, Vaccines, Multidisciplinary, Immune System Proteins, biology, Neurodegenerative Diseases, Animal Models, Hematology, Vaccination and Immunization, Body Fluids, 3.4 Vaccines, Neurological, Vertebrates, Anatomy, Adjuvant, Research Article, Down syndrome, General Science & Technology, Mouse Models, Mice, Transgenic, Research and Analysis Methods, Rodents, Antibodies, Blood Plasma, Vaccine Related, Model Organisms, mental disorders, Mental Health and Psychiatry, medicine, Acquired Cognitive Impairment, Animals, Inflammation, Amyloid beta-Peptides, business.industry, Neurosciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Newborn, Brain Disorders, Disease Models, Animal, Good Health and Well Being, Animals, Newborn, Gene Expression Regulation, Disease Models, Amniotes, biology.protein, Immunologic Techniques, Immunization, Septal Nuclei, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dfba69d0dfcfb75e94cc602c199ebe4Test
http://europepmc.org/articles/PMC4811554Test

المؤلفون: Nampally Sreenivasachary, Paolo Paganetti, Valérie Giriens, Luitgard Nagel-Steger, Markus Zweckstetter, Oskar Adolfsson, Andreas Muhs, Heiko Kroth, Maria Pihlgren, Andrea Pfeifer, Thomas Schrader, Sophie Lohmann, Yvan Varisco, Asad Jan, Nasrollah Rezaei-Ghaleh, María Pilar López-Deber, Annalisa Ansaloni, Hilal A. Lashuel, Wolfgang Froestl, Dieter Willbold

المصدر: Journal of Biological Chemistry
The journal of biological chemistry 287(41), 34786-34800 (2012). doi:10.1074/jbc.M112.357665
Kroth, H, Ansaloni, A, Varisco, Y, Jan, A, Sreenivasachary, N, Rezaei-Ghaleh, N, Giriens, V, Lohmann, S, López-Deber, M P, Adolfsson, O, Pihlgren, M, Paganetti, P, Froestl, W, Nagel-Steger, L, Willbold, D, Schrader, T, Zweckstetter, M, Pfeifer, A, Lashuel, H A & Muhs, A 2012, ' Discovery and structure activity relationship of small molecule inhibitors of toxic β-amyloid-42 fibril formation ', The Journal of biological chemistry, vol. 287, no. 41, pp. 34786-800 . https://doi.org/10.1074/jbc.M112.357665Test

مصطلحات موضوعية: 3-aminopyrazole, antagonists & inhibitors [Amyloid beta-Peptides], antagonists & inhibitors [Cytotoxins], antagonists & inhibitors [Peptide Fragments], Chemie, chemistry [Cytotoxins], Protein aggregation, Biochemistry, Protein Structure, Secondary, Hydrophobic effect, Structure-Activity Relationship, Protein structure, Cell Line, Tumor, mental disorders, Journal Article, Humans, Structure–activity relationship, Molecular Biology, chemistry.chemical_classification, Amyloid beta-Peptides, Cytotoxins, Chemistry, Research Support, Non-U.S. Gov't, In vitro toxicology, Molecular Bases of Disease, Hydrogen Bonding, Cell Biology, amyloid beta-protein (1-42), Small molecule, Peptide Fragments, Amino acid, chemistry [Peptide Fragments], ddc:540, chemistry [Pyrazoles], Pyrazoles, chemistry [Amyloid beta-Peptides], Hydrophobic and Hydrophilic Interactions, Linker

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4f1d6b8bb6eb1e9cd8d68fd89416ac0Test
https://hdl.handle.net/11858/00-001M-0000-000E-7305-311858/00-001M-0000-000E-7304-511858/00-001M-0000-000E-7300-DTest

المؤلفون: Maria Pihlgren, Andrea Pfeifer, Dorin Mlaki Ndao, Claude Nicolau, Marc Baldus, Deepak Nand, Rime Madani, David T. Hickman, María Pilar López-Deber, Luitgard Nagel-Steger, Andreas Muhs, Valérie Giriens, Annie St-Pierre, Dieter Willbold, Detlev Riesner, Alberto B. Silva, Hristina Karastaneva

المصدر: Journal of Biological Chemistry, 286(16), 13966. American Society for Biochemistry and Molecular Biology Inc.

مصطلحات موضوعية: Amyloid, Protein Folding, Magnetic Resonance Spectroscopy, Protein Conformation, Lipid-anchored protein, Peptide, Biology, Biochemistry, Epitope, Protein Structure, Secondary, chemistry.chemical_compound, Mice, Protein structure, Alzheimer Disease, Animals, Humans, Benzothiazoles, Neurodegeneration, Proteostasis Deficiencies, Molecular Biology, chemistry.chemical_classification, Vaccines, Circular Dichroism, Lipopeptide, Peptide Conformation, Cell Biology, Small molecule, Protein Structure, Tertiary, Mice, Inbred C57BL, Protein Misfolding, Thiazoles, chemistry, Immunoglobulin G, Liposomes, Protein Structure and Folding, Protein folding, Female, Peptides

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a337f57da46a893e698aab99ff2d80ecTest
https://pubmed.ncbi.nlm.nih.gov/21343310Test

المؤلفون: Maria Pihlgren, Valérie Giriens, Katarzyna Stanco-Piorko, Nathalie Chuard, Andrea Pfeifer, Fred Van Leuven, David T. Hickman, Andreas Muhs, Rime Madani, Ingrid Van der Auwera

المصدر: Alzheimer's & Dementia. 5

مصطلحات موضوعية: biology, Epidemiology, Amyloid beta, business.industry, Health Policy, Disease, Psychiatry and Mental health, Cellular and Molecular Neuroscience, Safety profile, Developmental Neuroscience, Immunology, biology.protein, Medicine, Neurology (clinical), Geriatrics and Gerontology, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::19107176f1d57f07408a6dcc24ac6b65Test
https://doi.org/10.1016/j.jalz.2009.04.952Test

المؤلفون: Luitgard Nagel-Steger, Valérie Giriens, Claude Nicolau, Andrea Pfeifer, Nathalie Chuard, Maria Pihlgren, Nadine Kolonko, Carine Meerschman, Roscoe O. Brady, Marie-Catherine Weingertner, Fred Van Leuven, Ingrid Van der Auwera, Andreas Muhs, Ruth Greferath, Masae Sugawara, David T. Hickman, Burkhard Bechinger, Detlev Riesner

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 104(23)

مصطلحات موضوعية: Amyloid, Alzheimer Vaccines, Peptide, Enzyme-Linked Immunosorbent Assay, Mice, Transgenic, Epitope, Amyloid beta-Protein Precursor, Mice, Immune system, Antigen, Alzheimer Disease, Animals, Antigens, Nuclear Magnetic Resonance, Biomolecular, chemistry.chemical_classification, Analysis of Variance, Multidisciplinary, Amyloid beta-Peptides, biology, Brain, Recognition, Psychology, Biological Sciences, Isotype, Molecular biology, Peptide Fragments, Epitope mapping, chemistry, Immunology, Liposomes, biology.protein, Cytokines, Antibody, Oligopeptides, Epitope Mapping

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c9d72a7b24bbd53c642153317489165Test
https://pubmed.ncbi.nlm.nih.gov/17517595Test