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1دورية أكاديمية
المؤلفون: Sandholm, Niina, Cole, Joanne B, Nair, Viji, Sheng, Xin, Liu, Hongbo, Ahlqvist, Emma, van Zuydam, Natalie, Dahlström, Emma H, Fermin, Damian, Smyth, Laura J, Salem, Rany M, Forsblom, Carol, Valo, Erkka, Harjutsalo, Valma, Brennan, Eoin P, McKay, Gareth J, Andrews, Darrell, Doyle, Ross, Looker, Helen C, Nelson, Robert G, Palmer, Colin, McKnight, Amy Jayne, Godson, Catherine, Maxwell, Alexander P, Groop, Leif, McCarthy, Mark I, Kretzler, Matthias, Susztak, Katalin, Hirschhorn, Joel N, Florez, Jose C, Groop, Per-Henrik
المصدر: Diabetologia. 65(9)
مصطلحات موضوعية: Human Genome, Kidney Disease, Prevention, Genetics, Diabetes, Biotechnology, 2.1 Biological and endogenous factors, Aetiology, Renal and urogenital, Metabolic and endocrine, Good Health and Well Being, Diabetes Mellitus, Type 2, Diabetic Nephropathies, Doublecortin-Like Kinases, Fibrosis, Genome-Wide Association Study, Humans, Intracellular Signaling Peptides and Proteins, Kidney, Polymorphism, Single Nucleotide, Protein Serine-Threonine Kinases, Diabetes complications, Diabetic kidney disease, Genome-wide association study, Meta-analysis, Transcriptomics, GENIE Consortium, Genome-wide association study, Meta-analysis, Transcriptomics, Clinical Sciences, Paediatrics and Reproductive Medicine, Public Health and Health Services, Endocrinology & Metabolism
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/7kb0h2rrTest
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2دورية أكاديمية
المؤلفون: The FinnDiane Study Group, Sandholm, Niina, Valo, Erkka, Tuomilehto, Jaakko, Harjutsalo, Valma, Groop, Per-Henrik
المساهمون: Medicum, HUS Abdominal Center, Clinicum, CAMM - Research Program for Clinical and Molecular Metabolism, Nefrologian yksikkö, HUS Internal Medicine and Rehabilitation, Department of Public Health, Research Programs Unit, Department of Medicine, Per Henrik Groop / Principal Investigator
مصطلحات موضوعية: 3121 General medicine, internal medicine and other clinical medicine, eGFR slope, type 1 diabetes
وصف الملف: application/pdf
العلاقة: The FinnDiane Study Group , Sandholm , N , Valo , E , Tuomilehto , J , Harjutsalo , V & Groop , P-H 2023 , ' Rate of Kidney Function Decline is Associated With Kidney and Heart Failure in Individuals With Type 1 Diabetes ' , Kidney International Reports , vol. 8 , no. 10 , pp. 2043-2055 . https://doi.org/10.1016/j.ekir.2023.07.026Test; ORCID: /0000-0003-4322-6942/work/151788042; ORCID: /0000-0003-0672-554X/work/151792155; 0e91ef21-0ed0-48cb-ae3a-815744b6ccb8; http://hdl.handle.net/10138/570292Test; 001164952700001
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3
المؤلفون: Dwivedi, Om Prakash, Barreiro, Karina, Käräjämäki, Annemari, Valo, Erkka, Giri, Anil K., Prasad, Rashmi B., Roy, Rishi Das, Thorn, Lena M., Rannikko, Antti, Holthöfer, Harry, Gooding, Kim M., Sourbron, Steven, Delic, Denis, Gomez, Maria F., Groop, Per-Henrik, Tuomi, Tiinamaija, Forsblom, Carol, Groop, Leif, Puhka, Maija
المصدر: iScience EXODIAB: Excellence of Diabetes Research in Sweden eSSENCE: The e-Science Collaboration. 26(5)
مصطلحات موضوعية: Medicin och hälsovetenskap, Klinisk medicin, Endokrinologi och diabetes, Medical and Health Sciences, Clinical Medicine, Endocrinology and Diabetes
الوصول الحر: https://lup.lub.lu.se/record/65011b76-a279-4b40-8e82-3ef0bcbaf801Test
http://dx.doi.org/10.1016/j.isci.2023.106686Test -
4دورية أكاديمية
المؤلفون: Mychaleckyj, Josyf C., Valo, Erkka, Ichimura, Takaharu, Ahluwalia, Tarunveer S., Dina, Christian, Miller, Rachel G., Shabalin, Ivan G., Gyorgy, Beata, Cao, JingJing, Onengut-Gumuscu, Suna, Satake, Eiichiro, Smiles, Adam M., Haukka, Jani K., Tregouet, David-Alexandre, Costacou, Tina, O'Neil, Kristina, Paterson, Andrew D., Forsblom, Carol, Keenan, Hillary A., Pezzolesi, Marcus G., Pragnell, Marlon, Galecki, Andrzej, Rich, Stephen S., Sandholm, Niina, Klein, Ronald, Klein, Barbara E., Susztak, Katalin, Orchard, Trevor J., Korstanje, Ron, King, George L., Hadjadj, Samy, Rossing, Peter, Bonventre, Joseph V., Groop, Per-Henrik, Warram, James H., Krolewski, Andrzej S.
المساهمون: CAMM - Research Program for Clinical and Molecular Metabolism, HUS Abdominal Center, Nefrologian yksikkö, Research Programs Unit, Clinicum, Medicum, Department of Medicine, Per Henrik Groop / Principal Investigator
مصطلحات موضوعية: type 1 diabetes, hydroxysteroid 17-beta dehydrogenase 14, end stage kidney disease, gene-based tests, rare variants, diabetic nephropathy, diabetic kidney disease, GENOME-WIDE ASSOCIATION, RENAL DECLINE, NEPHROPATHY, COMPLICATIONS, RISK, MICROALBUMINURIA, PREDICTORS, GENETICS, DURATION, GENES, 3121 General medicine, internal medicine and other clinical medicine
وصف الملف: application/pdf
العلاقة: Mychaleckyj , J C , Valo , E , Ichimura , T , Ahluwalia , T S , Dina , C , Miller , R G , Shabalin , I G , Gyorgy , B , Cao , J , Onengut-Gumuscu , S , Satake , E , Smiles , A M , Haukka , J K , Tregouet , D-A , Costacou , T , O'Neil , K , Paterson , A D , Forsblom , C , Keenan , H A , Pezzolesi , M G , Pragnell , M , Galecki , A , Rich , S S , Sandholm , N , Klein , R , Klein , B E , Susztak , K , Orchard , T J , Korstanje , R , King , G L , Hadjadj , S , Rossing , P , Bonventre , J V , Groop , P-H , Warram , J H & Krolewski , A S 2021 , ' Association of Coding Variants in Hydroxysteroid 17-beta Dehydrogenase 14 (HSD17B14) with Reduced Progression to End Stage Kidney Disease in Type 1 Diabetes ' , Journal of the American Society of Nephrology , vol. 32 , no. 10 , pp. 2634-2651 . https://doi.org/10.1681/ASN.2020101457Test; ORCID: /0000-0003-4322-6942/work/104579661; ORCID: /0000-0003-0672-554X/work/104579913; ddefafdd-ec8f-46d7-a02b-843a1a963f96; http://hdl.handle.net/10138/353497Test; 000714146900027
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5دورية أكاديمية
المؤلفون: FinnDiane Study Group, Lithovius, Raija, Antikainen, Anni A, Mutter, Stefan, Valo, Erkka, Forsblom, Carol, Harjutsalo, Valma, Sandholm, Niina, Groop, Per-Henrik
المساهمون: HUS Abdominal Center, Nefrologian yksikkö, CAMM - Research Program for Clinical and Molecular Metabolism, Clinicum, HUS Internal Medicine and Rehabilitation, Institute for Molecular Medicine Finland, Research Programs Unit, Medicum, Department of Medicine, Per Henrik Groop / Principal Investigator
مصطلحات موضوعية: CARDIOVASCULAR-DISEASE, COMPLICATIONS, GENOTYPE, HEART-DISEASE, LIFE, MODEL, MORTALITY, 3121 General medicine, internal medicine and other clinical medicine
وصف الملف: application/pdf
العلاقة: FinnDiane Study Group , Lithovius , R , Antikainen , A A , Mutter , S , Valo , E , Forsblom , C , Harjutsalo , V , Sandholm , N & Groop , P-H 2022 , ' Genetic Risk Score Enhances Coronary Artery Disease Risk Prediction in Individuals With Type 1 Diabetes ' , Diabetes Care , vol. 45 , no. 3 , pp. 734-741 . https://doi.org/10.2337/dc21-0974Test; Bibtex: lithovius2022genetic; ORCID: /0000-0003-4322-6942/work/117948031; ORCID: /0000-0003-0672-554X/work/117948714; ORCID: /0000-0003-2488-6830/work/117949228; ORCID: /0000-0002-8293-6982/work/117949639; 1c966c85-c353-4c99-9188-1e89b3866194; http://hdl.handle.net/10138/352474Test; 000834050800042
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6دورية أكاديمية
المؤلفون: Lithovius, Raija, Mutter, Stefan, Bezerra Parente, Erika, Mäkinen, Ville-Petteri, Valo, Erkka Antero, Harjutsalo, Valma, Groop, Per-Henrik
المساهمون: CAMM - Research Program for Clinical and Molecular Metabolism, Clinicum, HUS Internal Medicine and Rehabilitation, HUS Abdominal Center, Research Programs Unit, Department of Medicine, Per Henrik Groop / Principal Investigator, Diabetes and Obesity Research Program
مصطلحات موضوعية: 3121 General medicine, internal medicine and other clinical medicine, 3142 Public health care science, environmental and occupational health
وصف الملف: application/pdf
العلاقة: Lithovius , R , Mutter , S , Bezerra Parente , E , Mäkinen , V-P , Valo , E A , Harjutsalo , V & Groop , P-H 2023 , ' Medication profiling in women with type 1 diabetes highlights the importance of adequate, guideline-based treatment in low-risk groups ' , Scientific Reports , vol. 13 , no. 1 , 17893 . https://doi.org/10.1038/s41598-023-44695-2Test; ORCID: /0000-0003-0672-554X/work/146413027; ORCID: /0000-0002-8293-6982/work/146414030; ORCID: /0000-0002-8101-912X/work/146414369; d1346f1c-9596-4efe-8135-3fd3742517ec; http://hdl.handle.net/10138/566784Test; 001086765500061
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7دورية أكاديمية
المؤلفون: van Zuydam, Natalie R, Ahlqvist, Emma, Sandholm, Niina, Deshmukh, Harshal, Rayner, N William, Abdalla, Moustafa, Ladenvall, Claes, Ziemek, Daniel, Fauman, Eric, Robertson, Neil R, McKeigue, Paul M, Valo, Erkka, Forsblom, Carol, Harjutsalo, Valma, Perna, Annalisa, Rurali, Erica, Marcovecchio, M Loredana, Igo, Robert P, Salem, Rany M, Perico, Norberto, Lajer, Maria, Käräjämäki, Annemari, Imamura, Minako, Kubo, Michiaki, Takahashi, Atsushi, Sim, Xueling, Liu, Jianjun, van Dam, Rob M, Jiang, Guozhi, Tam, Claudia HT, Luk, Andrea OY, Lee, Heung Man, Lim, Cadmon KP, Szeto, Cheuk Chun, So, Wing Yee, Chan, Juliana CN, Ang, Su Fen, Dorajoo, Rajkumar, Wang, Ling, Clara, Tan Si Hua, McKnight, Amy-Jayne, Duffy, Seamus, Pezzolesi, Marcus G, Marre, Michel, Gyorgy, Beata, Hadjadj, Samy, Hiraki, Linda T, Ahluwalia, Tarunveer S, Almgren, Peter, Schulz, Christina-Alexandra, Orho-Melander, Marju, Linneberg, Allan, Christensen, Cramer, Witte, Daniel R, Grarup, Niels, Brandslund, Ivan, Melander, Olle, Paterson, Andrew D, Tregouet, David, Maxwell, Alexander P, Lim, Su Chi, Ma, Ronald CW, Tai, E Shyong, Maeda, Shiro, Lyssenko, Valeriya, Tuomi, Tiinamaija, Krolewski, Andrzej S, Rich, Stephen S, Hirschhorn, Joel N, Florez, Jose C, Dunger, David, Pedersen, Oluf, Hansen, Torben, Rossing, Peter, Remuzzi, Giuseppe, Brosnan, Mary Julia, Palmer, Colin NA, Groop, Per-Henrik, Colhoun, Helen M, Groop, Leif C, McCarthy, Mark I, Koivula, S, Uggeldahl, T, Forslund, T, Halonen, A, Koistinen, A, Koskiaho, P, Laukkanen, M, Saltevo, J, Tiihonen, M, Forsen, M, Granlund, H, Jonsson, A-C, Nyroos, B, Kinnunen, P, Orvola, A, Salonen, T, Vähänen, A, Paldanius, Kotka R, Riihelä, M
المصدر: Diabetes. 67(7)
مصطلحات موضوعية: Diabetes, Genetics, Human Genome, Aetiology, 2.1 Biological and endogenous factors, Metabolic and endocrine, Good Health and Well Being, Adult, Aged, Aged, 80 and over, Case-Control Studies, Diabetes Mellitus, Type 2, Diabetic Nephropathies, Female, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Kidney Failure, Chronic, Male, Middle Aged, Polymorphism, Single Nucleotide, Renal Insufficiency, Chronic, Finnish Diabetic Nephropathy Study, Hong Kong Diabetes Registry Theme-based Research Scheme Project Group, Warren 3 and Genetics of Kidneys in Diabetes (GoKinD) Study Group, GENIE (GEnetics of Nephropathy an International Effort) Consortium, Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications (EDIC) Research Group, SUrrogate markers for Micro- and Macrovascular hard endpoints for Innovative diabetes Tools (SUMMIT) Consortium, Medical and Health Sciences, Endocrinology & Metabolism
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/37m0v97nTest
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8دورية أكاديمية
المؤلفون: Kidney Precision Medicine Project, Limonte, Christine P., Valo, Erkka, Drel, Viktor, Forsblom, Carol, Sandholm, Niina, Groop, Per-Henrik, de Boer, Ian H.
المساهمون: HUS Internal Medicine and Rehabilitation, HUS Abdominal Center, CAMM - Research Program for Clinical and Molecular Metabolism, University of Helsinki, Nefrologian yksikkö, Institute for Molecular Medicine Finland, Research Programs Unit, Medicum, Doctoral Programme in Clinical Research, Department of Medicine, Per Henrik Groop / Principal Investigator, Clinicum
مصطلحات موضوعية: General medicine, internal medicine and other clinical medicine
وصف الملف: application/pdf
العلاقة: Acknowledgments. The authors are grateful for the participation of the study volunteers and for the effort and dedication of all the staff who took part in subject recruitment. Funding. JDRF Network grant 3-SRA-2016-104 (PI:KS) provided major support for this study. The FinnDiane Study was funded by the Folk-h€alsan Research Foundation, the Wilhelm and Else Stockmann Foundation, the Liv och H€alsa Society, the Novo Nordisk Foundation (NNF OC0013659), the Helsinki University Hospital Research Funds, and the Academy of Finland (299200, 275614, 316664). The EDC study was funded by National Institutes of Health (NIH) grant DK34818 and the Rossi Memorial Fund. CACTI was funded by NIH grants R01HL113029, R01HL079611, RC1DK086958, and R01DE026480. JDRF Network grant 3-SRA-2016-104 (PI:KS) provided major support for this study. The FinnDiane Study was funded by the Folk-häalsan Research Foundation, the Wilhelm and Else Stockmann Foundation, the Liv och Häalsa Society, the Novo Nordisk Foundation (NNF OC0013659), the Helsinki University Hospital Research Funds, and the Academy of Finland (299200, 275614, 316664). The EDC study was funded by National Institutes of Health (NIH) grant DK34818 and the Rossi Memorial Fund. CACTI was funded by NIH grants R01HL113029, R01HL079611, RC1DK086958, and R01DE026480. C.P.L. was funded by NIDDK grants T32DK007467 and R01DK088762 and Northwest Kidney Cen-ters. R.G.N. was supported by the Intramural Research Program of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), and the imaging of kidney tissue specimens was also supported in part by the American Diabetes Association (Clinical Science Award 1-08-42). L.N. and J.Z. were partially supported by NIDDK grant 1R01DK110541-01A1. The development of the urine proteomics assay was partially supported by the University of Washington Nutrition Obesity Research Center (P30 DK035816) and Diabetes Research Center (P30 DK017047). This study was also supported, in part, by the George M. O’Brien Michigan Kidney Translational Core Center, funded by NIH/ NIDDK grant 2P30-DK-081943. The KPMP is funded by the following grants from the NIDDK: U2C DK114886, UH3DK114861, UH3DK114866, UH3DK114870, UH3DK114908, UH3DK114915, UH3DK114926, UH3DK114907, UH3DK114920, UH3DK114923, UH3DK114933, and UH3DK114937. I.H.d.B. has obtained research funding from the NIH and the American Diabetes Association. S.E.R. reports grants through the Joslin Diabetes Center with NIDDK. M.K. reports grants outside the sub-mitted work through the University of Michigan with NIH and JDRF. Center with Bayer and AstraZeneca. M.K. reports grants and contracts outside the submitted work through the University of Michigan with Chan Zuckerberg Initiative, AstraZeneca, Novo Nordisk, Eli Lilly, Gilead, Goldfinch Bio, Janssen, Boehringer Ingelheim, Moderna, European Union Innovative Medicine Initiative, Certa, Chinook, amfAR, Angion, Renalytix, Tra-vere Therapeutics, Regeneron Pharmaceuticals, and IONIS and consulting fees through the University of Michigan from Astellas Pharma, Poxel, Janssen, and UCB. Additionally, M.K., W.J., and V.N. have a patent, PCT/EP2014/073413 “Biomarkers and methods for progression prediction for chronic kidney disease,” licensed. No other potential conflicts of interest relevant to this article were reported. Author Contributions. C.P.L. drafted the manuscript. E.V. conducted statistical analyses for the primary cohort study. C.P.L., V.D., D.M., W.J., V.N., and S.A. additionally conducted secondary statistical and bioinformatics analyses. V.D. led mouse and cell culture studies. A.N.H., K.S., and I.H.d.B. serve as primary investigators for this proteomics project and obtained funding. C.F. and N.S. contributed to the study design. T.S.A. participated in data management and cleaning. P.R., P.-H.G., J.K.S.-B., T.C., and T.J.O. serve as primary investigators of the four studied cohorts and obtained funding. S.S.W. serves as primary investigator for the BKBC. R.G.N. serves as primary investigator for the Pima Indian cohort, and M.K. serves as the principal investigator for the Pima cohort tran-scriptome data analysis. J.F.O., R.D.T., S.E.R., and S.S.W. serve as heads of KPMP recruitment sites. A.N.H., K.S., and I.H.d.B. supervised the project. All authors contributed to interpretation of results and read, edited, and approved the final manuscript. C.P.L. and E.V. are the guarantors of this work and, as such, had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Prior Presentation. Parts of this study were presented in abstract form at the American Society of Nephrology's Kidney Week 2020, Denver, CO, 20–25 October 2020. C.P.L. was funded by NIDDK grants T32DK007467 and R01DK088762 and Northwest Kidney Centers. R.G.N. was supported by the Intramural Research Program of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), and the imaging of kidney tissue specimens was also supported in part by the American Diabetes Association (Clinical Science Award 1-08-42). L.N. and J.Z. were partially supported by NIDDK grant 1R01DK110541-01A1. The development of the urine proteomics assay was partially supported by the University of Washington Nutrition Obesity Research Center (P30 DK035816) and Diabetes Research Center (P30 DK017047). This study was also supported, in part, by the George M. O’Brien Michigan Kidney Translational Core Center, funded by NIH/ NIDDK grant 2P30-DK-081943. The KPMP is funded by the following grants from the NIDDK: U2C DK114886, UH3DK114861, UH3DK114866, UH3DK114870, UH3DK114908, UH3DK114915, UH3DK114926, UH3DK114907, UH3DK114920, UH3DK114923, UH3DK114933, and UH3DK114937. I.H.d.B. has obtained research funding from the NIH and the American Diabetes Association. S.E.R. reports grants through the Joslin Diabetes Center with NIDDK. M.K. reports grants outside the submitted work through the University of Michigan with NIH and JDRF. Duality of Interest. I.H.d.B. has received equipment and supplies for research from Medtronic and Abbott and consults for Boehringer Ingelheim and Ironwood. P.-H.G. has received investigator research grants from Eli Lilly and Roche and lecture honoraria from AstraZeneca, Boehringer Ingelheim, Eli Lilly, Elo Water, Genzyme, Medscape, Merck Sharp & Dohme (MSD), Novartis, Novo Nordisk, and Sanofi. P.-H.G. is an advisor for AbbVie, Astra-Zeneca, Boehringer Ingelheim, Cebix, Eli Lilly, Janssen, Medscape, MSD, Novartis, Novo Nordisk, and Sanofi. P.R. has received consultancy and/or speaking fees (to his institution) from AbbVie, Astellas, AstraZeneca, Bayer, Boehringer Ingelheim, Eli Lilly, Gilead Sciences, Novo Nordisk, Vifor Pharma, and Sanofi and research grants from AstraZeneca and Novo Nordisk. K.S. is on the advisory board for Boehringer Ingelheim and Janssen and has received research support from Merck and Boehringer Ingelheim. S.E.R. reports grants and contracts through the Joslin Diabetes; Kidney Precision Medicine Project , Limonte , C P , Valo , E , Drel , V , Forsblom , C , Sandholm , N , Groop , P-H & de Boer , I H 2022 , ' Urinary Proteomics Identifies Cathepsin D as a Biomarker of Rapid eGFR Decline in Type 1 Diabetes ' , Diabetes Care , vol. 45 , no. 6 , pp. 1416-1427 . https://doi.org/10.2337/dc21-2204Test; ORCID: /0000-0003-4322-6942/work/119158459; ORCID: /0000-0003-0672-554X/work/119158692; http://hdl.handle.net/10138/351469Test; 8e06339f-6952-40fe-bf04-b10d99aa2b27; 85131270263; 000886431800020
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9دورية أكاديمية
المؤلفون: GENIE Consortium, Sandholm, Niina, Cole, Joanne B., Nair, Viji, Forsblom, Carol, Valo, Erkka, Harjutsalo, Valma, Groop, Leif, Groop, Per-Henrik, Tuomilehto, Jaakko
المساهمون: Research Programs Unit, Medicum, HUS Abdominal Center, University of Helsinki, Nefrologian yksikkö, CAMM - Research Program for Clinical and Molecular Metabolism, Clinicum, Centre of Excellence in Complex Disease Genetics, Institute for Molecular Medicine Finland, Leif Groop Research Group, Department of Medicine, Per Henrik Groop / Principal Investigator, Department of Public Health
مصطلحات موضوعية: Diabetes complications, Diabetic kidney disease, Genetics, Genome-wide association study, Meta-analysis, Transcriptomics, TYPE-1, NEPHROPATHY, EXPRESSION, INSULIN, GLUCOSE, IA-2, 3121 General medicine, internal medicine and other clinical medicine
وصف الملف: application/pdf
العلاقة: Open Access funding provided by University of Helsinki including Helsinki University Central Hospital. This study was funded by JDRF (grants S-SRA-2014-276-Q-R and 17-2013-7) and by NIDDK R01 DK105154. Research in FinnDiane was supported by Folkhalsan Research Foundation, Wilhelm and Else Stockmann Foundation, `Liv och Halsa' Society, Helsinki University Central Hospital Research Funds (EVO TYH2018207), Academy of Finland (299200 and 316664) and Novo Nordisk Foundation (NNF OC0013659). Acquisition of clinical data and samples from the Pima Indians was supported by the Intramural Research Program of the National Institute of Diabetes and Digestive and Kidney Diseases and by the ADA (Clinical Science Award 1-08-CR-42). JBC was funded by the National Institute of Diabetes and Digestive and Kidney Diseases (K99DK127196). EA was funded by grants from the Swedish Research Council (2017-02688, 2020-02191) and the Novo Nordisk Foundation (NNF18OC0034408). The study funders were not involved in the design of the study; the collection, analysis, and interpretation of data; writing the report; and did not impose any restrictions regarding the publication of the report.; GENIE Consortium , Sandholm , N , Cole , J B , Nair , V , Forsblom , C , Valo , E , Harjutsalo , V , Groop , L , Groop , P-H & Tuomilehto , J 2022 , ' Genome-wide meta-analysis and omics integration identifies novel genes associated with diabetic kidney disease ' , Diabetologia , vol. 65 , no. 9 , pp. 1495-1509 . https://doi.org/10.1007/s00125-022-05735-0Test; ORCID: /0000-0003-4322-6942/work/117506284; ORCID: /0000-0003-0672-554X/work/117506587; d002aa68-816e-4e09-816e-010082d5be60; http://hdl.handle.net/10138/347019Test; 000817826200001
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10دورية أكاديمية
المؤلفون: Valo, Erkka, Colombo, Marco, Sandholm, Niina, McGurnaghan, Stuart J., Blackbourn, Luke A. K., Dunger, David B., McKeigue, Paul M., Forsblom, Carol, Groop, Per-Henrik, Colhoun, Helen M., Turner, Charles, Dalton, R. Neil
المساهمون: HUS Internal Medicine and Rehabilitation, HUS Abdominal Center, CAMM - Research Program for Clinical and Molecular Metabolism, Nefrologian yksikkö, Medicum, Clinicum, Research Programs Unit, Department of Medicine, Per Henrik Groop / Principal Investigator
مصطلحات موضوعية: PLASMA, STABILITY, ACID, HOMOCYSTEINE, GLUTAMINE, PROTEINS, RESIDUES, IMPACT, 3111 Biomedicine
وصف الملف: application/pdf
العلاقة: This study was supported by funding from Juvenile Diabetes Research Foundation (Ref. 1-SRA-2016-333-M-R); Chief Scientist Office (Ref. ETM/47); Diabetes UK (Ref. 10/0004010); Folkhalsan Research Foundation; the Wilhelm and Else Stockmann Foundation; the Liv och Halsa Society; the Novo Nordisk Foundation (NNF OC0013659); the Helsinki University Hospital Research Funds; the Academy of Finland (299200 and 316664); the Finnish Diabetes Research Foundation; and the University of Helsinki Research Foundation. In-kind contribution from Scottish Diabetes Research Network.; Valo , E , Colombo , M , Sandholm , N , McGurnaghan , S J , Blackbourn , L A K , Dunger , D B , McKeigue , P M , Forsblom , C , Groop , P-H , Colhoun , H M , Turner , C & Dalton , R N 2022 , ' Effect of serum sample storage temperature on metabolomic and proteomic biomarkers ' , Scientific Reports , vol. 12 , no. 1 , 4571 . https://doi.org/10.1038/s41598-022-08429-0Test; ORCID: /0000-0003-4322-6942/work/111175112; ORCID: /0000-0003-0672-554X/work/111175274; 8f5cafda-f369-4bfe-bf7c-730659b9ffa3; http://hdl.handle.net/10138/342614Test; 000770396200031