دورية أكاديمية
Anastomotic leak following oesophagectomy: research priorities from an international Delphi consensus study
| العنوان: | Anastomotic leak following oesophagectomy: research priorities from an international Delphi consensus study |
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| المؤلفون: | Sivesh K Kamarajah, Imran Mohamed, Dmitri Nepogodiev, Richard P T Evans, James Hodson, Ewen A Griffiths, Pritam Singh, Derek Alderson, James Bundred, Richard Evans, James Gossage, Benjamin Jefferies, Siobhan McKay, Kobby Siaw-Acheampong, Richard van Hillegersberg, Ravinder Vohra, Kasun Wanigsooriya, Tony Whitehouse, A Bekele, M P Achiam, H Ahmed, A Ainsworth, K Akhtar, N Akkapulu, W Al-Khyatt, M Alasmar, B N Alemu, R Alfieri, B Alkhaffaf, L S Alvarez, V Amahu, N A Andreollo, F Arias, A Ariyarathenam, A Arndt, A Athanasiou, J S Azagra, C Baban, R Babor, E Baili, A Balla, E Beenen, M Bendixen, J Bennett, D Bergeat, A J Bernardes, D Bernardi, R Berrisford, A Bianchi, M Bjelovic, N Blencowe, A Boddy, S Bogdan, J Bolger, L Bonavina, G Bouras, S Bouwense, D Bowrey, D Bragg, T N Bright, S Broderick, G Buduhan, B Byrne, D Carey, P Carroll, P Carrott, R Casaca, R G Castro, J Catton, M P Cerdeira, A C Chang, A Charalabopoulos, A Chaudry, C Choh, B Ciprian, C Ciubotaru, P Coe, E Colak, R B Colino, N Colucci, P M Costa, K Daniela, N Das, A Davies, N Davies, G de Manzoni, I D del Val, S Dexter, J Dolan, N Donlon, C Donohoe, J Duffy, S Dwerryhouse, J H Egberts, C Ekwunife, A Elhadi, M Elhadi, J A Elliott, H Elnagar, F Elnagar, H A Faraj, N Farooq, N Fearon, E Fekaj, M Forshaw, J Freire, G Ga??evski, J Gaedcke, S Giacopuzzi, M M Gij??n, S Gisbertz, H Golcher, A Gordon, J Gossage, E Griffiths, P Grimminger, A Guner, S Gutknecht, T Harustiak, J Hedberg, J Heisterkamp, M Hii, A Hindmarsh, J Holm, S Hornby, A Isik, J Izbicki, V Jagadesham, S Jaunoo, J Johansson, M A Johnson, B Johnston, S Kapoulas, J Kauppi, J H Kauppila, A Kechagias, M Kelly, C Kelty, A Kennedy, M Khan, S Khattak, B Kidane, D W Kjaer, B Klarenbeek, D P Korkolis, R M Koshy, S Krantz, S Lagarde, M H Larsen, P C Lau, P C Leeder, J S Leite, T Liakakos, A Madhavan, S I Mahdi, H A Mahendran, H Mahmoodzadeh, A Majbar, D Manatakis, S Markar, I Martijnse, B Matei, P Matos da Costa, K McCormack, S McNally, S Meril??inen, N Merrett, M Migliore, F Mingol, D Mitton, S S Mogoanta, S P M??nig, K Moorthy, M Muhinga, M Mwachiro, A Naeem, I Nasir, M Navidi, I Negoi, V Negoi???, S K Niazi, M Nilsson, A Pazdro, M Pera, C J Perez, K Perivoliotis, C Peters, A W Phillips, A Powell, L Prove, P H Pucher, S Rahman, J V R??s??nen, M Read, M Reeh, D Reim, J Reynolds, W B Robb, K Robertson, B Rodica, G Rosero, C Rosman, L Saadeh, EG Santos, J Saunders, R Sayyed, D Schizas, R R Scurtu, D Sekhniaidze, P A Serralheiro, B Sevin?, B Sgromo, O Shakeel, M Siemsen, R Skipworth, B Smith, A Soares, J Spillane, M A Steliga, M Sundbom, A Sydiuk, A M L Takahashi, M Talbot, B Tan, M A Tareen, N Tewari, M Tez, D Theodorou, A Tita, E Toledo, P J Townend, T Triantafyllou, M Trugeda, O Tucker, P Turner, V Turrado, T Underwood, S Vaccari, M Valmasoni, M van Berge Henegouwen, G van Boxel, J W van den Berg, P van der Sluis, R van Hillegersberg, J J B van Lanschot, F van Workum, J Vickers, J Videira, Y Viswanath, R Vohra, K Voon, M Wadley, R Walker, B Wallner, T N Walsh, J Weindelmayer, N Welch, T Wheatley, B Wijnhoven, L F Wong, F Yanni, J Yeung |
| المساهمون: | K Kamarajah, Sivesh, Mohamed, Imran, Nepogodiev, Dmitri, T Evans, Richard P, Hodson, Jame, A Griffiths, Ewen, Singh, Pritam, Alderson, Derek, Bundred, Jame, Evans, Richard, Gossage, Jame, Jefferies, Benjamin, Mckay, Siobhan, Siaw-Acheampong, Kobby, van Hillegersberg, Richard, Vohra, Ravinder, Wanigsooriya, Kasun, Whitehouse, Tony, Bekele, A, P Achiam, M, Ahmed, H, Ainsworth, A, Akhtar, K, Akkapulu, N, Al-Khyatt, W, Alasmar, M, N Alemu, B, Alfieri, R, Alkhaffaf, B, S Alvarez, L, Amahu, V, A Andreollo, N, Arias, F, Ariyarathenam, A, Arndt, A, Athanasiou, A, S Azagra, J, Baban, C, Babor, R, Baili, E, Balla, A, Beenen, E, Bendixen, M, Bennett, J, Bergeat, D, J Bernardes, A, Bernardi, D, Berrisford, R, Bianchi, A, Bjelovic, M, Blencowe, N, Boddy, A, Bogdan, S, Bolger, J, Bonavina, L, Bouras, G, Bouwense, S, Bowrey, D, Bragg, D, N Bright, T, Broderick, S, Buduhan, G, Byrne, B, Carey, D, Carroll, P, Carrott, P, Casaca, R, G Castro, R, Catton, J, P Cerdeira, M, C Chang, A, Charalabopoulos, A, Chaudry, A, Choh, C, Ciprian, B, Ciubotaru, C, Coe, P, Colak, E, B Colino, R, Colucci, N, M Costa, P, Daniela, K, Das, N, Davies, A, Davies, N, DE MANZONI, Giovanni, D del Val, I, Dexter, S, Dolan, J, Donlon, N, Donohoe, C, Duffy, J |
| سنة النشر: | 2021 |
| المجموعة: | Università degli Studi di Verona: Catalogo dei Prodotti della Ricerca (IRIS) |
| مصطلحات موضوعية: | anastomotic leak, esophagectomy |
| الوصف: | Background: The Oesophago-Gastric Anastomosis Audit (OGAA) is an international collaborative group set up to study anastomotic leak outcomes after oesophagectomy for cancer. This Delphi study aimed to prioritize future research areas of unmet clinical need in RCTs to reduce anastomotic leaks.Methods: A modified Delphi process was overseen by the OGAA committee, national leads, and engaged clinicians from high-income countries (HICs) and low/middle-income countries (LMICs). A three-stage iterative process was used to prioritize research topics, including a scoping systematic review (stage 1), and two rounds of anonymous electronic voting (stages 2 and 3) addressing research priority and ability to recruit. Stratified analyses were performed by country income.Results: In stage 1, the steering committee proposed research topics across six domains: preoperative optimization, surgical oncology, technical approach, anastomotic technique, enhanced recovery and nutrition, and management of leaks. In stages 2 and stage 3, 192 and 171 respondents respectively participated in online voting. Prioritized research topics include prehabilitation, anastomotic technique, and timing of surgery after neoadjuvant chemo(radio)therapy. Stratified analyses by country income demonstrated no significant differences in research priorities between HICs and LMICs. However, for ability to recruit, there were significant differences between LMICs and HICs for themes related to the technical approach (minimally invasive, width of gastric tube, ischaemic preconditioning) and location of the anastomosis.Conclusion: Several areas of research priority are consistent across LMICs and HICs, but discrepancies in ability to recruit by country income will inform future study design. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| العلاقة: | info:eu-repo/semantics/altIdentifier/pmid/33640931; info:eu-repo/semantics/altIdentifier/wos/WOS:000637023600045; volume:108; issue:1; firstpage:66; lastpage:73; numberofpages:8; journal:BRITISH JOURNAL OF SURGERY; https://hdl.handle.net/11562/1095652Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85111600363 |
| DOI: | 10.1093/bjs/znaa034 |
| الإتاحة: | https://doi.org/10.1093/bjs/znaa034Test https://hdl.handle.net/11562/1095652Test |
| حقوق: | info:eu-repo/semantics/restrictedAccess |
| رقم الانضمام: | edsbas.990D2918 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1093/bjs/znaa034 |
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