There have been many published studies on how COVID-19 can affect the liver and how the severity of liver damage can influence the clinical course of COVID-19. The article describes the features of the biochemical parameters of the liver in different age groups developing with a new coronavirus infection using the example of observations in the department of gastroenterology. In patients under 60 years of age with liver cirrhosis in combination with Covid-19, along with deeper changes in liver tests, a decrease in hemoglobin, leukopenia and thrombocytopenia was observed.