المؤلفون: Ruuth, Maija, Soronen, Jarkko, Kaiharju, Essi, Merikanto, Krista, Perttilä, Julia, Metso, Jari, Lee-Rueckert, Miriam, Taskinen, Marja-Riitta, Kovanen, Petri T., Öörni, Katariina, Olkkonen, Vesa M., Jauhiainen, Matti S., Laurila, Pirkka-Pekka

المساهمون: Medicum, Research Programs Unit, University of Helsinki, Clinicum, Diabetes and Obesity Research Program, Marja-Riitta Taskinen Research Group, Department of Anatomy, Department of Medical and Clinical Genetics, Institute for Molecular Medicine Finland, HUS Internal Medicine and Rehabilitation, HUS Heart and Lung Center

مصطلحات موضوعية: USF1, High density lipoproteins, Cholesterol efflux, Cholesterol accumulation, Macrophage, Hepatocyte, Inflammation, FAMILIAL COMBINED HYPERLIPIDEMIA, UPSTREAM TRANSCRIPTION FACTOR-1, HIGH-DENSITY-LIPOPROTEINS, LYSOSOMAL ACID LIPASE, ESTER HYDROLASE 1, FOAM CELLS, HIGH-RISK, ATHEROSCLEROSIS, ASSOCIATION, CAPACITY, 3111 Biomedicine, 1182 Biochemistry, cell and molecular biology

وصف الملف: application/pdf

العلاقة: This study was supported by the Finnish Foundation for Cardiovascular Research (MJ, VMO, PPL, JS), Jenny and Antti Wihuri Foundation (MJ, JS), Novo-Nordisk Foundation (MRT, VMO), Paavo Nurmi Foundation (MJ, PPL, JS, VMO), Academy of Finland (Grant #257545 to MJ and #265940 to KO), Finska Lakaresallskapet (PPL), Aarne Koskelo Foundation (PPL), Emil Aaltonen Foundation (PPL), Foundation for Diabetes Research (PPL, JS), Magnus Ehrnrooth Foundation (PPL, VMO), Jane and Aatos Erkko Foundation (MJ), Sigrid Juselius Foundation (PPL, VMO) and The Finnish Medical Foundation (PPL). Wihuri Research Institute (MR, MLR, KO, PTK) is maintained by the Jenny and Antti Wihuri Foundation.; Ruuth , M , Soronen , J , Kaiharju , E , Merikanto , K , Perttilä , J , Metso , J , Lee-Rueckert , M , Taskinen , M-R , Kovanen , P T , Öörni , K , Olkkonen , V M , Jauhiainen , M S & Laurila , P-P 2018 , ' USF1 deficiency alleviates inflammation, enhances cholesterol efflux and prevents cholesterol accumulation in macrophages ' , Lipids in Health and Disease , vol. 17 , 285 . https://doi.org/10.1186/s12944-018-0930-2Test; ORCID: /0000-0001-8903-0617/work/52400340; ORCID: /0000-0002-6229-3588/work/90756889; 85058544449; de8fd278-34aa-46f9-8fe9-18202e39e9cb; http://hdl.handle.net/10138/287689Test; 000453307200005

الإتاحة: http://hdl.handle.net/10138/287689Test

المؤلفون: Julia Perttilä, Maija Ruuth, Marja-Riitta Taskinen, Jari Metso, Petri T. Kovanen, Katariina Öörni, Vesa M. Olkkonen, Miriam Lee-Rueckert, Essi Kaiharju, Jarkko Soronen, Pirkka-Pekka Laurila, Matti Jauhiainen, Krista Merikanto

المساهمون: Medicum, Research Programs Unit, University of Helsinki, Clinicum, Diabetes and Obesity Research Program, Marja-Riitta Taskinen Research Group, Department of Anatomy, Department of Medical and Clinical Genetics, Institute for Molecular Medicine Finland, HUS Internal Medicine and Rehabilitation, HUS Heart and Lung Center

المصدر: Lipids in Health and Disease
Lipids in Health and Disease, Vol 17, Iss 1, Pp 1-11 (2018)

مصطلحات موضوعية: 0301 basic medicine, Male, Cholesterol accumulation, Macrophage, FAMILIAL COMBINED HYPERLIPIDEMIA, Endocrinology, Diabetes and Metabolism, Clinical Biochemistry, Gene Expression, FOAM CELLS, 030204 cardiovascular system & hematology, Small hairpin RNA, chemistry.chemical_compound, Mice, 0302 clinical medicine, Endocrinology, LYSOSOMAL ACID LIPASE, Hepatocyte, Cholesterol efflux, lcsh:RC620-627, Chemokine CCL2, Mice, Knockout, ASSOCIATION, USF1, 3. Good health, UPSTREAM TRANSCRIPTION FACTOR-1, lcsh:Nutritional diseases. Deficiency diseases, medicine.anatomical_structure, Cholesterol, lipids (amino acids, peptides, and proteins), Efflux, medicine.symptom, Lipoproteins, HDL, ATP Binding Cassette Transporter 1, medicine.medical_specialty, Inflammation, CAPACITY, 03 medical and health sciences, Internal medicine, medicine, Animals, Humans, Secretion, Obesity, High density lipoproteins, Triglyceride, Research, Biochemistry (medical), Cholesterol, HDL, ESTER HYDROLASE 1, HIGH-RISK, 030104 developmental biology, ATHEROSCLEROSIS, chemistry, HIGH-DENSITY-LIPOPROTEINS, Macrophages, Peritoneal, 1182 Biochemistry, cell and molecular biology, Upstream Stimulatory Factors, 3111 Biomedicine, Insulin Resistance

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::808dc827fcb0334e91d17e61bc009b6dTest
http://europepmc.org/articles/PMC6293625Test