المؤلفون: van den Brom, Rob R H, van der Geest, Kornelis S M, Brouwer, Elisabeth, Hospers, Geke A P, Boots, Annemieke M H

المصدر: van den Brom , R R H , van der Geest , K S M , Brouwer , E , Hospers , G A P & Boots , A M H 2018 , ' Enhanced expression of PD-1 and other activation markers by CD4+T cells of young but not old patients with metastatic melanoma ' , Cancer Immunology Immunotherapy , vol. 67 , no. 6 , pp. 925-933 . https://doi.org/10.1007/s00262-018-2148-6Test

مصطلحات موضوعية: Melanoma, Immunosenescence, Aging, PD-1, CTLA-4, UNTREATED MELANOMA, T-CELLS, IPILIMUMAB, SURVIVAL, AGE, CANCER, PEMBROLIZUMAB, NIVOLUMAB, CD4(+)

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/28bb0964-26ac-45cf-8d80-d56c4b53f158Test

الإتاحة: https://doi.org/10.1007/s00262-018-2148-6Test
https://hdl.handle.net/11370/28bb0964-26ac-45cf-8d80-d56c4b53f158Test
https://research.rug.nl/en/publications/28bb0964-26ac-45cf-8d80-d56c4b53f158Test
https://pure.rug.nl/ws/files/56058151/Enhanced_expression_of_PD_1_and_other_activation.pdfTest

المؤلفون: Motzer, Robert J., Tannir, Nizar M., McDermott, David F., Arén Frontera, Osvaldo, Melichar, Bohuslav, Choueiri, Toni K., Plimack, Elizabeth R., Barthélémy, Philippe, Porta, Camillo, George, Saby, Powles, Thomas, Donskov, Frede, Neiman, Victoria, Kollmannsberger, Christian K., Salman, Pamela, Gurney, Howard, Hawkins, Robert, Ravaud, Alain, Grimm, Marc-Oliver, Bracarda, Sergio, Barrios, Carlos H., Tomita, Yoshihiko, Castellano, Daniel, Rini, Brian I., Chen, Allen C., Mekan, Sabeen, McHenry, M. Brent, Wind-Rotolo, Megan, Doan, Justin, Sharma, Padmanee, Hammers, Hans J., Escudier, Bernard, CheckMate 214 Investigators, missing, Rottey, Sylvie

المصدر: NEW ENGLAND JOURNAL OF MEDICINE ; ISSN: 0028-4793 ; ISSN: 1533-4406

مصطلحات موضوعية: Medicine and Health Sciences, General Medicine, PHASE-III TRIAL, INTERFERON-ALPHA, UNTREATED MELANOMA, 1ST-LINE TREATMENT, SYMPTOM INDEX, KIDNEY CANCER, OPEN-LABEL, PAZOPANIB, THERAPY, MULTICENTER

وصف الملف: application/pdf

العلاقة: https://biblio.ugent.be/publication/8730625Test; http://hdl.handle.net/1854/LU-8730625Test; http://dx.doi.org/10.1056/nejmoa1712126Test; https://biblio.ugent.be/publication/8730625/file/8730628Test

الإتاحة: https://doi.org/10.1056/nejmoa1712126Test
https://biblio.ugent.be/publication/8730625Test
http://hdl.handle.net/1854/LU-8730625Test
https://biblio.ugent.be/publication/8730625/file/8730628Test

المؤلفون: Krähenbühl, Lukas, Goldinger, Simone M, Mangana, Joanna, Kerl, Katrin, Chevolet, Ines, Brochez, Lieve, Horak, Christine, Levesque, Mitch, Dummer, Reinhard, Cheng, Phil F

المصدر: NEOPLASIA ; ISSN: 1476-5586

مصطلحات موضوعية: Medicine and Health Sciences, CLINICAL-PRACTICE GUIDELINES, INDOLEAMINE 2, 3-DIOXYGENASE, UNTREATED MELANOMA, CANCER, NIVOLUMAB, IPILIMUMAB, DIAGNOSIS, ANTIBODY, MARKER, PD-L1

وصف الملف: application/pdf

العلاقة: https://biblio.ugent.be/publication/8566836Test; http://hdl.handle.net/1854/LU-8566836Test; http://dx.doi.org/10.1016/j.neo.2017.12.002Test; https://biblio.ugent.be/publication/8566836/file/8566840Test

الإتاحة: https://doi.org/10.1016/j.neo.2017.12.002Test
https://biblio.ugent.be/publication/8566836Test
http://hdl.handle.net/1854/LU-8566836Test
https://biblio.ugent.be/publication/8566836/file/8566840Test

المؤلفون: Antonia, Scott J., Lopez-Martin, Jose A., Bendell, Johanna, Ott, Patrick A., Taylor, Matthew, Eder, Joseph Paul, Jaeger, Dirk, Pietanza, M. Catherine, Le, Dung T., de Braud, Filippo, Morse, Michael A., Ascierto, Paolo A., Horn, Leora, Amin, Asim, Pillai, Rathi N., Evans, Jeffry, Chau, Ian, Bono, Petri, Atmaca, Akin, Sharma, Padmanee, Harbison, Christopher T., Lin, Chen-Sheng, Christensen, Olaf, Calvo, Emiliano

المساهمون: Clinicum, Translational Cancer Biology (TCB) Research Programme, Department of Oncology

مصطلحات موضوعية: III TRIAL, METASTATIC MELANOMA, UNTREATED MELANOMA, MYASTHENIA-GRAVIS, EXTENSIVE-DISEASE, TREATMENT OPTIONS, COMBINATION, THERAPY, IRINOTECAN, DOCETAXEL, 3122 Cancers

وصف الملف: application/pdf

العلاقة: Bristol-Myers Squibb.; Antonia , S J , Lopez-Martin , J A , Bendell , J , Ott , P A , Taylor , M , Eder , J P , Jaeger , D , Pietanza , M C , Le , D T , de Braud , F , Morse , M A , Ascierto , P A , Horn , L , Amin , A , Pillai , R N , Evans , J , Chau , I , Bono , P , Atmaca , A , Sharma , P , Harbison , C T , Lin , C-S , Christensen , O & Calvo , E 2016 , ' Nivolumab alone and nivolumab plus ipilimumab in recurrent small-cell lung cancer (CheckMate 032) : a multicentre, open-label, phase 1/2 trial ' , Lancet Oncology , vol. 17 , no. 7 , pp. 883-895 . https://doi.org/10.1016/S1470-2045Test(16)30098-5; 84971620553; 42459f38-f78a-4ec2-ba18-5312ae089400; http://hdl.handle.net/10138/224071Test; 000378947100054

الإتاحة: http://hdl.handle.net/10138/224071Test

المؤلفون: Seymour, Lesley, Bogaerts, Jan, Perrone, Andrea, Ford, Robert, Schwartz, Lawrence H., Mandrekar, Sumithra, Lin, Nancy U., Litiere, Saskia, Dancey, Janet, Chen, Alice, Hodi, F. Stephen, Therasse, Patrick, Hoekstra, Otto S., Shankar, Lalitha K., Wolchok, Jedd D., Ballinger, Marcus, Caramella, Caroline, de Vries, Elisabeth G. E.

المصدر: Seymour , L , Bogaerts , J , Perrone , A , Ford , R , Schwartz , L H , Mandrekar , S , Lin , N U , Litiere , S , Dancey , J , Chen , A , Hodi , F S , Therasse , P , Hoekstra , O S , Shankar , L K , Wolchok , J D , Ballinger , M , Caramella , C , de Vries , E G E & RECIST Working Grp 2017 , ' iRECIST : Guidelines for response criteria for use in trials testing immunotherapeutics ....

مصطلحات موضوعية: CELL LUNG-CANCER, IMMUNE-RELATED RESPONSE, SOLID TUMORS, UNTREATED MELANOMA, DOUBLE-BLIND, NIVOLUMAB, IPILIMUMAB, PEMBROLIZUMAB, CARBOPLATIN, COMBINATION

العلاقة: https://research.rug.nl/en/publications/786948bb-d52d-414c-97de-06ed99a2cc2bTest

الإتاحة: https://doi.org/10.1016/S1470-2045Test(17)30074-8
https://hdl.handle.net/11370/786948bb-d52d-414c-97de-06ed99a2cc2bTest
https://research.rug.nl/en/publications/786948bb-d52d-414c-97de-06ed99a2cc2bTest
http://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC5648544&blobtype=pdfTest

المؤلفون: Jacquelot, N., Roberti, M. P., Enot, D. P., Rusakiewicz, S., Ternes, N., Jegou, S., Woods, D. M., Sodre, A. L., Hansen, M., Meirow, Y., Sade-Feldman, M., Burra, A., Kwek, S. S., Flament, C., Messaoudene, M., Duong, C. P. M., Chen, L., Kwon, B. S., Anderson, A. C., Kuchroo, V. K., Weide, B., Aubin, F., Borg, C., Dalle, S., Beatrix, O., Ayyoub, M., Balme, B., Tomasic, G., Di Giacomo, A. M., Maio, M., Schadendorf, D., Melero, I., Dreno, B., Khammari, A., Dummer, R., Levesque, M., Koguchi, Y., Fong, L., Lotem, M., Baniyash, M., Schmidt, H., Svane, I. M., Kroemer, G., Marabelle, A., Michiels, S., Cavalcanti, A., Smyth, M. J., Weber, S., Eggermont, A. M., Zitvogel, L.

المصدر: Jacquelot , N , Roberti , M P , Enot , D P , Rusakiewicz , S , Ternes , N , Jegou , S , Woods , D M , Sodre , A L , Hansen , M , Meirow , Y , Sade-Feldman , M , Burra , A , Kwek , S S , Flament , C , Messaoudene , M , Duong , C P M , Chen , L , Kwon , B S , Anderson , A C , Kuchroo , V K , Weide , B , Aubin , F , Borg ....

مصطلحات موضوعية: STAGE-III MELANOMA, TUMOR-INFILTRATING LYMPHOCYTES, CIRCULATING SOLUBLE FAS, BREAST-CANCER PATIENTS, CELL LUNG-CANCER, METASTATIC MELANOMA, CLINICAL-SIGNIFICANCE, UNTREATED MELANOMA, COMBINED NIVOLUMAB, PROGNOSTIC IMPACT

العلاقة: https://pure.au.dk/portal/en/publications/67994a06-e269-4431-ac46-8ad81e09e7cdTest

الإتاحة: https://doi.org/10.1038/s41467-017-00608-2Test
https://pure.au.dk/portal/en/publications/67994a06-e269-4431-ac46-8ad81e09e7cdTest
http://www.scopus.com/inward/record.url?scp=85029870193&partnerID=8YFLogxKTest

المؤلفون: Arasanz, H, Gato-Canas, M, Zuazo, M, Ibanez-Vea, M, Breckpot, K, Kochan, G, Escors, D

المصدر: Oncotarget , 8 (31) pp. 51936-51945. (2017)

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Oncology, Cell Biology, PD-L1, PDL1, PD1, B7-H1, cancer, RECEPTOR DOWN-MODULATION, PD-L1 CO-STIMULATION, CBL-B, UNTREATED MELANOMA, PROGRAMMED DEATH-1, EFFECTOR FUNCTION, ZETA-CHAIN, ACTIVATION, ANTIGEN, PROTEIN

وصف الملف: text

العلاقة: https://discovery.ucl.ac.uk/id/eprint/1556540/1/Escors_PD1%20signal%20transduction%20pathways%20in%20T%20cells.pdfTest; https://discovery.ucl.ac.uk/id/eprint/1556540Test/

الإتاحة: https://discovery.ucl.ac.uk/id/eprint/1556540/1/Escors_PD1%20signal%20transduction%20pathways%20in%20T%20cells.pdfTest
https://discovery.ucl.ac.uk/id/eprint/1556540Test/

المؤلفون: Furness, AJ, Quezada, SA, Peggs, KS

المصدر: Immunotherapy , 8 (7) pp. 763-766. (2016)

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Immunology, CTLA-4, Heterogeneity, Neoantigens, PD-1, Tumor-Infiltrating Lymphocytes, Cytolytic T-Lymphocytes, Metastatic Melanoma, CTLA-4 Blockade, Untreated Melanoma, HLA-A2 Melanomas, Lung-Cancer, Ipilimumab, Antigen, Nivolumab

وصف الملف: text

العلاقة: https://discovery.ucl.ac.uk/id/eprint/1502534/1/Furness_et%20al.%20AMENDED.pdfTest; https://discovery.ucl.ac.uk/id/eprint/1502534Test/

الإتاحة: https://discovery.ucl.ac.uk/id/eprint/1502534/1/Furness_et%20al.%20AMENDED.pdfTest
https://discovery.ucl.ac.uk/id/eprint/1502534Test/

المصدر: Lancet Oncology. 18(3):143-152

مصطلحات موضوعية: DOUBLE-BLIND, CARBOPLATIN, CELL LUNG-CANCER, IPILIMUMAB, UNTREATED MELANOMA, NIVOLUMAB, IMMUNE-RELATED RESPONSE, PEMBROLIZUMAB, COMBINATION, SOLID TUMORS

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=dris___01423::61edf14671fe0fc0c699517a9388f04eTest
https://research.rug.nl/en/publications/786948bb-d52d-414c-97de-06ed99a2cc2bTest

المؤلفون: Rathi N. Pillai, Patrick A. Ott, Scott J. Antonia, Chen Sheng Lin, Matthew H. Taylor, M. Catherine Pietanza, Petri Bono, Paolo A. Ascierto, Jeffry Evans, Filippo de Braud, Joseph Paul Eder, Jose A. Lopez-Martin, Olaf Christensen, Akin Atmaca, Dung T. Le, Michael A. Morse, Dirk Jäger, Padmanee Sharma, Christopher T. Harbison, Emiliano Calvo, Asim Amin, Leora Horn, Ian Chau, Johanna C. Bendell

المساهمون: Clinicum, Translational Cancer Biology (TCB) Research Programme, Department of Oncology

المصدر: The Lancet Oncology. 17:883-895

مصطلحات موضوعية: Male, 0301 basic medicine, Lung Neoplasms, IRINOTECAN, THERAPY, Gastroenterology, 0302 clinical medicine, Antineoplastic Combined Chemotherapy Protocols, METASTATIC MELANOMA, MYASTHENIA-GRAVIS, DOCETAXEL, education.field_of_study, Antibodies, Monoclonal, EXTENSIVE-DISEASE, Middle Aged, Prognosis, 3. Good health, Survival Rate, Nivolumab, Oncology, Tolerability, Docetaxel, 030220 oncology & carcinogenesis, Female, TREATMENT OPTIONS, medicine.drug, medicine.medical_specialty, 3122 Cancers, Population, Ipilimumab, 03 medical and health sciences, Internal medicine, medicine, Humans, COMBINATION, education, Aged, Neoplasm Staging, III TRIAL, business.industry, UNTREATED MELANOMA, Rovalpituzumab tesirine, Interim analysis, Small Cell Lung Carcinoma, Surgery, Regimen, 030104 developmental biology, Neoplasm Recurrence, Local, business, Follow-Up Studies

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4f8ac848747dfb4834bedd5225382ccTest
https://doi.org/10.1016/s1470-2045Test(16)30098-5