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1دورية أكاديمية
المؤلفون: Dillemuth, Pyry, Karskela, Tuomas, Ayo, Abiodun, Ponkamo, Jesse, Kunnas, Jonne, Rajander, Johan, Tynninen, Olli, Roivainen, Anne, Laakkonen, Pirjo, Airaksinen, Anu J., Li, Xiang-Guo
المساهمون: CAN-PRO - Translational Cancer Medicine Program, Medicum, HUSLAB, Department of Pathology, Pirjo Maarit Laakkonen / Principal Investigator, Laboratory Animal Centre, Helsinki Institute of Life Science HiLIFE, Digital Precision Cancer Medicine (iCAN)
مصطلحات موضوعية: ACooP, Autoradiography, Fatty acid binding protein 3, Fluorine-18, Peptide, Peptide radiolabeling, PET, S-acylation, 3111 Biomedicine, 317 Pharmacy, 3126 Surgery, anesthesiology, intensive care, radiology
وصف الملف: application/pdf
العلاقة: Tissue staining was digitized using a 3DHISTECH Pannoramic 250 FLASH II slide scanner at the Genome Biology Unit supported by HiLIFE and the Faculty of Medicine, University of Helsinki and Biocenter Finland. Mass spectrometry analyses were performed at the Turku Proteomics Facility supported by Biocenter Finland. H&E staining was performed at the Histocore unit, University of Turku. NMR analysis was performed in Turku Centre for Chemical and Molecular Analytics, Åbo Akademi University and Univeristy of Turku, Turku, Finland. We thank the research grants from the Finnish Cancer Foundation, the Finnish Cultural Foundation, the Turku University Foundation, Turku University Hospital and Sigrid Jusélius Foundation. This research was partially supported by the Research Council of Finland’s Flagship InFLAMES and the funding Decision Numbers were 337530 and 357910.; Dillemuth , P , Karskela , T , Ayo , A , Ponkamo , J , Kunnas , J , Rajander , J , Tynninen , O , Roivainen , A , Laakkonen , P , Airaksinen , A J & Li , X-G 2024 , ' Radiosynthesis, structural identification and in vitro tissue binding study of [ 18 F]FNA-S-ACooP, a novel radiopeptide for targeted PET imaging of fatty acid binding protein 3 ' , EJNMMI Radiopharmacy and Chemistry , vol. 9 , no. 1 , 16 . https://doi.org/10.1186/s41181-024-00245-3Test; ORCID: /0000-0003-4173-162X/work/157158094; ORCID: /0000-0002-9620-095X/work/157158150; http://hdl.handle.net/10138/574092Test; 94ee9b90-bf9a-4355-96b2-e997f7b01bca; 85186749117; 001173131200002
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2دورية أكاديمية
المؤلفون: Wallgren-Pettersson, Carina, Jokela, Manu, Lehtokari, Vilma-Lotta, Tyynismaa, Henna, Sainio, Markus T., Ylikallio, Emil, Tynninen, Olli, Pelin, Katarina, Auranen, Mari
المساهمون: Medicum, Department of Medical and Clinical Genetics, Faculty Common Matters (Faculty of Medicine), STEMM - Stem Cells and Metabolism Research Program, Centre of Excellence in Stem Cell Metabolism, Research Programs Unit, Henna Tyynismaa / Principal Investigator, Faculty of Medicine, HUS Neurocenter, Neurologian yksikkö, Department of Neurosciences, Clinicum, HUSLAB, Department of Pathology, Katarina Pelin / Principal Investigator, Molecular and Integrative Biosciences Research Programme
مصطلحات موضوعية: Congenital myopathy, Muscle hypertonia, TPM2, TPM3, Trismus, Tropomyosin, 3112 Neurosciences
وصف الملف: application/pdf
العلاقة: The authors thank the patients for their participation in the study, and Marilotta Turunen for excellent technical assistance. The study was funded by the Finska Läkaresällskapet, the Medicinska Understödsföreningen Liv och Hälsa, the Jane and Aatos Erkko Foundation ( 3769–4fd21 ) and the Folkhälsan Research Foundation (101003 and 101004).; Wallgren-Pettersson , C , Jokela , M , Lehtokari , V-L , Tyynismaa , H , Sainio , M T , Ylikallio , E , Tynninen , O , Pelin , K & Auranen , M 2024 , ' Variants in tropomyosins TPM2 and TPM3 causing muscle hypertonia ' , Neuromuscular Disorders , vol. 35 , pp. 29-32 . https://doi.org/10.1016/j.nmd.2023.12.006Test; ORCID: /0000-0002-2493-2422/work/153473747; ORCID: /0000-0001-5178-0703/work/153473925; ORCID: /0000-0002-7040-7266/work/153474193; ORCID: /0000-0002-8276-0972/work/153479793; 85183007503; 488e820b-99c4-4ed8-af25-453fe89ac19a; http://hdl.handle.net/10138/571198Test; 001161106800001
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3دورية أكاديمية
المؤلفون: Auvinen, Eeva, Honkimaa, Anni, Laine, Pia, Passerini, Sara, Moens, Ugo, Pietropaolo, Valeria, Saarela, Mika, Maunula, Leena, Mannonen, Laura, Tynninen, Olli, Haapasalo, Hannu, Rauramaa, Tuomas, Auvinen, Petri, Liimatainen, Hanna
المساهمون: Eeva Auvinen / Principal Investigator, HUSLAB, Medicum, Department of Virology, HUS Helsinki and Uusimaa Hospital District, Institute of Biotechnology, HUS Neurocenter, Neurologian yksikkö, Clinicum, Helsinki One Health (HOH), Leena Maunula / Principal Investigator, Food Hygiene and Environmental Health, Departments of Faculty of Veterinary Medicine, Food and Environmental Virology Research Group, Faculty Common Matters (Faculty of Biology and Environmental Sciences), Mirja Puolakkainen / Principal Investigator, Department of Pathology, DNA Sequencing and Genomics
مصطلحات موضوعية: Diagnostics, JC polyomavirus, Ngs, Pml, Targeted sequencing, 11832 Microbiology and virology
وصف الملف: application/pdf
العلاقة: We thank Anu Kaitonen for valuable technical assistance. We thank the personnel of the DNA Sequencing and Genomics Laboratory, Institute of Biotechnology, University of Helsinki (supported by HiLIFE and Biocenter Finland) , for running the NGS assays.; Auvinen , E , Honkimaa , A , Laine , P , Passerini , S , Moens , U , Pietropaolo , V , Saarela , M , Maunula , L , Mannonen , L , Tynninen , O , Haapasalo , H , Rauramaa , T , Auvinen , P & Liimatainen , H 2024 , ' Differentiation of highly pathogenic strains of human JC polyomavirus in neurological patients by next generation sequencing ' , Journal of Clinical Virology , vol. 171 , 105652 . https://doi.org/10.1016/j.jcv.2024.105652Test; ORCID: /0000-0002-0841-5353/work/156646053; ORCID: /0000-0002-2094-985X/work/156646852; ORCID: /0000-0003-2364-2594/work/156653520; http://hdl.handle.net/10138/573979Test; bea538bc-db6b-4926-a88a-c226100f1140; 001188466000001
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4دورية أكاديمية
المؤلفون: Honkimaa, Anni, Laine, Pia, Suppula, Joni, Tynninen, Olli, Saarela, Mika, Laakso, Sini M, Hetemäki, Iivo, Liimatainen, Hanna, Auvinen, Petri, Auvinen, Eeva
المساهمون: Emil Aaltonen Foundation, Finnish Society for the Study of Infectious Diseases, Maire Taponen Foundation
المصدر: The Journal of Infectious Diseases ; ISSN 0022-1899 1537-6613
مصطلحات موضوعية: Infectious Diseases, Immunology and Allergy
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5
المؤلفون: Pulkka, Olli Pekka, Viisanen, Leevi, Tynninen, Olli, Laaksonen, Maria, Reichardt, Peter, Reichardt, Annette, Eriksson, Mikael, Hall, Kirsten Sundby, Wardelmann, Eva, Nilsson, Bengt, Sihto, Harri, Joensuu, Heikki
المصدر: Journal of Cellular and Molecular Medicine. 26(4):1083-1094
مصطلحات موضوعية: Medicin och hälsovetenskap, Klinisk medicin, Cancer och onkologi, Medical and Health Sciences, Clinical Medicine, Cancer and Oncology
الوصول الحر: https://lup.lub.lu.se/record/a2fa3cba-3a9d-4de2-8bd9-21931dcb3572Test
http://dx.doi.org/10.1111/jcmm.17163Test -
6دورية أكاديمية
المؤلفون: Sievers, Philipp, Sill, Martin, Schrimpf, Daniel, Abdullaev, Zied, Donson, Andrew, Lake, Jessica, Friedel, Dennis, Scheie, David, Tynninen, Olli, Rauramaa, Tuomas, Vepsäläinen, Kaisa, Samuel, David, Chapman, Rebecca, Grundy, Richard, Pajtler, Kristian, Tauziède-Espariat, Arnault, Métais, Alice, Varlet, Pascale, Snuderl, Matija, Jacques, Thomas, Aldape, Kenneth, Reuss, David, Korshunov, Andrey, Wick, Wolfgang, Pfister, Stefan, von Deimling, Andreas, Sahm, Felix, Jones, David
المساهمون: Institut de psychiatrie et neurosciences de Paris (IPNP - U1266 Inserm), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)
المصدر: ISSN: 2397-768X ; npj Precision Oncology ; https://u-paris.hal.science/hal-04086709Test ; npj Precision Oncology, 2023, 7 (30), ⟨10.1038/s41698-023-00372-1⟩.
مصطلحات موضوعية: [SDV]Life Sciences [q-bio]
العلاقة: hal-04086709; https://u-paris.hal.science/hal-04086709Test; https://u-paris.hal.science/hal-04086709/documentTest; https://u-paris.hal.science/hal-04086709/file/Sievers%20et%20al.%20-%202023%20-%20Pediatric-type%20high-grade%20neuroepithelial%20tumors%20w.pdfTest
الإتاحة: https://doi.org/10.1038/s41698-023-00372-1Test
https://u-paris.hal.science/hal-04086709Test
https://u-paris.hal.science/hal-04086709/documentTest
https://u-paris.hal.science/hal-04086709/file/Sievers%20et%20al.%20-%202023%20-%20Pediatric-type%20high-grade%20neuroepithelial%20tumors%20w.pdfTest -
7دورية أكاديمية
المؤلفون: Sihvonen, Aleksi J., Laakso, Sini M., Tynninen, Olli, Saaren-Seppälä, Heikki, Löfberg, Mervi
المساهمون: Centre of Excellence in Music, Mind, Body and Brain, Department of Psychology and Logopedics, Cognitive Brain Research Unit, Music, Ageing and Rehabilitation Team, Brain, Music and Learning, Clinicum, Research Programs Unit, HUS Neurocenter, Neurologian yksikkö, Medicum, HUSLAB, Department of Pathology, HUS Head and Neck Center, Silmäklinikka
مصطلحات موضوعية: IgG4-related disease, Brain, Case report, Pachymeningitis, Parenchymal, Rituximab, Neurosciences, Neurology and psychiatry
وصف الملف: application/pdf
العلاقة: Sihvonen , A J , Laakso , S M , Tynninen , O , Saaren-Seppälä , H & Löfberg , M 2023 , ' Complete remission of central nervous system manifestations of IgG4-related disease with rituximab - a case report ' , Therapeutic advances in neurological disorders , vol. 16 , 17562864231186091 . https://doi.org/10.1177/17562864231186091Test; ORCID: /0000-0002-0104-2849/work/140313905; http://hdl.handle.net/10138/563900Test; cfa8e2aa-3983-45c1-b3de-ac811567ca31; 001028714500001
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8دورية أكاديمية
المؤلفون: Kantonen, Jonas, Mahzabin, Shamita, Mäyränpää, Mikko, Tynninen, Olli, Paetau, Anders, Andersson, Noora, Sajantila, Antti, Vapalahti, Olli, Carpen, Olli, Kekäläinen, Eliisa, Kantele, Anu, Myllykangas, Liisa
المساهمون: HUSLAB, Department of Pathology, Medicum, University of Helsinki, Helsinki University Hospital Area, TRIMM - Translational Immunology Research Program, Faculty of Medicine, Research Programs Unit, HUS Children and Adolescents, Department of Forensic Medicine, Helsinki One Health (HOH), Veterinary Microbiology and Epidemiology, Veterinary Biosciences, Olli Pekka Vapalahti / Principal Investigator, Viral Zoonosis Research Unit, Department of Virology, Precision Cancer Pathology, Olli Mikael Carpen / Principal Investigator, Immunobiology Research Program, Department of Medicine, HUS Inflammation Center, HUMI - Human Microbiome Research, PaleOmics Laboratory
مصطلحات موضوعية: COVID-19, ischemia, neuropathology, Neurosciences, Neurology and psychiatry, Biomedicine
وصف الملف: application/pdf
العلاقة: We thank Kristiina Nokelainen, Katja Lindstrom, Kirsi Kallioheimo, Anne Nummisto and Pirjo Niiniketo for excellent technical assistance. Teemu Smura, Suvi Kuivanen, Jenni M. Virtanen, Eili Huhtamo and Tarja Sironen are acknowledged for setting up and managing the RT-PCRs. We also thank Tomas Strandin for the SARS-CoV2/2019 nCoV anti-Spike antibody, Minna Poyhonen for discussions and Mia Kero for providing the antibody information. The study was funded by the Academy of Finland (294817, 334812, 308913), the Helsinki University Hospital Fund, the Liv och Halsa Foundation, the Finnish Medical Foundation and the Juho Vainio Foundation.; Kantonen , J , Mahzabin , S , Mäyränpää , M , Tynninen , O , Paetau , A , Andersson , N , Sajantila , A , Vapalahti , O , Carpen , O , Kekäläinen , E , Kantele , A & Myllykangas , L 2020 , ' Neuropathologic features of four autopsied COVID-19 patients ' , Brain Pathology , vol. 30 , no. 6 , pp. 1012-1016 . https://doi.org/10.1111/bpa.12889Test; ORCID: /0000-0001-6045-108X/work/127003095; ORCID: /0000-0003-2270-6824/work/127003584; ORCID: /0000-0002-2237-5466/work/127003635; ORCID: /0000-0002-0877-9640/work/127008359; http://hdl.handle.net/10138/353230Test; 5f74960e-ee7a-4e5e-98fc-fb42bebba409; 000563308500001
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9دورية أكاديمية
المؤلفون: Tanner, Laura M., Tynninen, Olli, Piippo, Kirsi, Puhakka, Antti M.
المساهمون: Department of Medical and Clinical Genetics, Medicum, HUS Diagnostic Center, HUS Helsinki and Uusimaa Hospital District, HUSLAB, Department of Pathology, Pregnancy and Genes, HUS Gynecology and Obstetrics, Department of Obstetrics and Gynecology
مصطلحات موضوعية: Spectrum, 3123 Gynaecology and paediatrics
وصف الملف: application/pdf
العلاقة: Tanner , L M , Tynninen , O , Piippo , K & Puhakka , A M 2023 , ' X-linked pyruvate dehydrogenase complex deficiency due to a novel PDHA1 variant associated with structural brain abnormalities in a fetus ' , Prenatal Diagnosis , vol. 43 , no. 6 , pp. 730-733 . https://doi.org/10.1002/pd.6349Test; 480c53e8-e5e5-4a32-84df-0b00e8132439; http://hdl.handle.net/10138/359614Test; 000988188500001
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10دورية أكاديمية
المؤلفون: Honkimaa, Anni, Suppula, Joni, Tynninen, Olli, Saarela, Mika, Liimatainen, Hanna, Laine, Pia, Auvinen, Petri, Auvinen, Eeva
المساهمون: Medicum, Department of Virology, HUSLAB, Department of Pathology, HUS Helsinki and Uusimaa Hospital District, HUS Neurocenter, Neurologian yksikkö, Clinicum, Institute of Biotechnology, DNA Sequencing and Genomics, Eeva Auvinen / Principal Investigator
مصطلحات موضوعية: JC polyomavirus, JCPyV, Pml, miRNA, microRNA, Progressive multifocal leukoencephalopathy, 3121 General medicine, internal medicine and other clinical medicine, 11832 Microbiology and virology
وصف الملف: application/pdf
العلاقة: Honkimaa , A , Suppula , J , Tynninen , O , Saarela , M , Liimatainen , H , Laine , P , Auvinen , P & Auvinen , E 2023 , ' JC Polyomavirus Modifies the Expression of Human microRNAs in Progressive Multifocal Leukoencephalopathy Brain ' , Journal of Infectious Diseases , vol. 228 , no. 7 , pp. 829-833 . https://doi.org/10.1093/infdis/jiad083Test; ORCID: /0000-0002-2094-985X/work/144385698; ORCID: /0000-0003-2364-2594/work/144393713; f672352c-6bad-43d6-a476-c110a48eb172; http://hdl.handle.net/10138/566076Test; 000970753000001