Early deaths from ischaemic heart disease in childhood-onset type 1 diabetes
| العنوان: | Early deaths from ischaemic heart disease in childhood-onset type 1 diabetes |
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| المؤلفون: | Richard G. Feltbower, Roger C Parslow, H. Jonathan Bodansky, Trina C Evans-Cheung |
| المصدر: | Archives of Disease in Childhood. 103:981-983 |
| بيانات النشر: | BMJ, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Pediatrics, Adolescent, Population, Myocardial Ischemia, 030209 endocrinology & metabolism, Risk Assessment, Death Certificates, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Cause of Death, Diabetes mellitus, Epidemiology, medicine, Humans, cardiovascular diseases, 030212 general & internal medicine, Age of Onset, education, education.field_of_study, Type 1 diabetes, business.industry, Mortality rate, Middle Aged, medicine.disease, United Kingdom, Early type, Diabetes Mellitus, Type 1, Pediatrics, Perinatology and Child Health, Cohort, Female, Ischaemic heart disease, business |
| الوصف: | AimsThe risk of ischaemic heart disease (IHD) death in early type 1 diabetes onset was assessed using death certification data.MethodsThe Yorkshire Register of type 1 Diabetes in Children and Young People was linked to clinically validated death certification data for those diagnosed under 15 years. Standardised mortality ratios (SMRs) were calculated using the England and Wales population and IHD death rates between 1978 and 2014 by 5-year age group and sex.ResultsThe cohort included 4382 individuals (83 097 person years). Of 156 deaths, nine were classed as IHD deaths before clinical validation. After clinical validation, 14 IHD deaths were classified, with an SMR of 13.8 (95% CI 8.2 to 23.3) and median age at death of 35.1 years (range 21.9–47.9 years).ConclusionsThere is an early emergence of death from IHD in early onset type 1 diabetes. Underascertainment of IHD deaths was present without clinical validation of death certification. |
| وصف الملف: | application/pdf |
| تدمد: | 1468-2044 0003-9888 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c46bdd2014def082c63bc2d8e078f586Test https://doi.org/10.1136/archdischild-2017-314265Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....c46bdd2014def082c63bc2d8e078f586 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14682044 00039888 |
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