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المؤلفون: Amit M. Oza, Tony W. Ho, J. Carl Barrett, Jonathan Ledermann, Jane D. Robertson, Mark J. O'Connor, C. Blake Gilks, Julia V. Burnier, Katherine Karakasis, Tony Panzarella, Ursula Matulonis, Claire Scott, Elise C. Kohn, David Bowtell, Charlie Gourley, Stan Kaye, Jerry S. Lanchbury, Kirsten M. Timms, Darren R. Hodgson, Sarah Runswick, Brian A. Dougherty, Zhongwu Lai, Stephanie Lheureux
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82f3cf8b7ca62d919c2266027f7eb78dTest
https://doi.org/10.1158/1078-0432.c.6527036.v1Test -
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المؤلفون: Amit M. Oza, Tony W. Ho, J. Carl Barrett, Jonathan Ledermann, Jane D. Robertson, Mark J. O'Connor, C. Blake Gilks, Julia V. Burnier, Katherine Karakasis, Tony Panzarella, Ursula Matulonis, Claire Scott, Elise C. Kohn, David Bowtell, Charlie Gourley, Stan Kaye, Jerry S. Lanchbury, Kirsten M. Timms, Darren R. Hodgson, Sarah Runswick, Brian A. Dougherty, Zhongwu Lai, Stephanie Lheureux
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dce4e67ff8abc1435358f47967de32eTest
https://doi.org/10.1158/1078-0432.22468700.v1Test -
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المؤلفون: Haydar, Frangoul, Tony W, Ho, Selim, Corbacioglu
المصدر: The New England journal of medicine. 384(23)
مصطلحات موضوعية: Genetics, Gene Editing, Anemia, business.industry, Thalassemia, Cell, beta-Thalassemia, MEDLINE, General Medicine, Disease, Anemia, Sickle Cell, medicine.disease, medicine.anatomical_structure, Genome editing, medicine, CRISPR, Humans, Clustered Regularly Interspaced Short Palindromic Repeats, CRISPR-Cas Systems, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7185d2dc04cd039c5aa2a02c7be1d4f5Test
https://pubmed.ncbi.nlm.nih.gov/34107197Test -
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المؤلفون: Angela Yen, Damiano Rondelli, la Fuente Josu de, Amanda M. Li, Jennifer Domm, Montalembert Mariane de, Tony W. Ho, Donna A. Wall, Brenda K. Eustace, Juergen Foell, Sujit Sheth, Haydar Frangoul, Rupert Handgretinger, Akshay Sharma, Sandeep Soni, Antonis Kattamis, Andrew Kernytsky, Franco Locatelli, Stephan A. Grupp, M. Domenica Cappellini, Julie A. Lekstrom-Himes, Selim Corbacioglu, David Altshuler, Markus Y. Mapara, Yi-Shan Chen, Martin H. Steinberg
مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, Anemia, Thalassemia, Cell, CD34, Disease, Biology, 030204 cardiovascular system & hematology, 03 medical and health sciences, 0302 clinical medicine, Genome editing, hemic and lymphatic diseases, Fetal hemoglobin, medicine, CRISPR, 030212 general & internal medicine, Progenitor cell, Enhancer, Genetics, business.industry, Obstetrics and Gynecology, General Medicine, medicine.disease, Haematopoiesis, medicine.anatomical_structure, Settore MED/38 - PEDIATRIA GENERALE E SPECIALISTICA, Immunology, Bone marrow, CRISPR-Cas9, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::294f2984b8848005c8f160412c9178cdTest
https://hdl.handle.net/10807/228473Test -
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المؤلفون: Jon Penterman, Nicole Flanagan, J Mike Toomey, Holly J Whitton, Sarah J Spencer, Tony W. Ho, Aditya S Khedkar, Courtney A Shearer, Thomas J. Cradick, Hemangi G. Chaudhari, Maria C Lei Zhang, John D Kulman, Elaine Huang, Andrew Kernytsky, Alexander W Needham
المصدر: CRISPR J
مصطلحات موضوعية: Gene Editing, Cas9, Genome, Human, Streptococcus pyogenes, Hybrid capture, High-Throughput Nucleotide Sequencing, Correction, Computational biology, Biology, Genome, Homology (biology), Genomic Instability, HEK293 Cells, Genome editing, Assessment methods, Genetics, CRISPR, Humans, Clustered Regularly Interspaced Short Palindromic Repeats, Guide RNA, CRISPR-Cas Systems, Artifacts, Biotechnology, RNA, Guide, Kinetoplastida
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db9eda3e0461ce3a33585625bbdb6c1eTest
https://pubmed.ncbi.nlm.nih.gov/33616443Test -
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المؤلفون: Yimeng Lu, Markus Y. Mapara, Niraj Shanbhag, Damiano Rondelli, Franco Locatelli, C. Fernández, Sandeep Soni, Donna A. Wall, Yael Bobruff, John K. Wu, Stephan A. Grupp, Sarah D. Mulcahey, Sujit Sheth, Haydar Frangoul, Antonis Kattamis, Maria Domenica Cappellini, Tony W. Ho, J Lekstrom-Himes, Mariane de Montalembert, Martin H. Steinberg, Selim Corbacioglu, Josu de la Fuente, Rupert Handgretinger, Michael J. Weinstein, Suzan Imren
المصدر: Transplantation and Cellular Therapy. 27:S72-S73
مصطلحات موضوعية: Transplantation, business.industry, Thalassemia, Cell, CD34, Cell Biology, Hematology, Disease, medicine.disease, Haematopoiesis, medicine.anatomical_structure, Immunology, Molecular Medicine, Immunology and Allergy, Medicine, CRISPR, In patient, Progenitor cell, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::89e261f83fae91cabdc601c32eeadf0eTest
https://doi.org/10.1016/s2666-6367Test(21)00101-9 -
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المؤلفون: David D.L. Bowtell, Sarah Runswick, Tony W. Ho, Clare L. Scott, Kirsten Timms, Mark J. O'Connor, Blake Gilks, Jerry S. Lanchbury, Tony Panzarella, Katherine Karakasis, Elise C. Kohn, Stanley B. Kaye, J. Carl Barrett, Zhongwu Lai, Brian Dougherty, Julia V. Burnier, Darren Hodgson, Amit M. Oza, Charlie Gourley, Stephanie Lheureux, Ursula A. Matulonis, Jane Robertson, Jonathan A. Ledermann
المصدر: Lheureux, S, Lai, Z, Dougherty, B A, Runswick, S, Hodgson, D, Timms, K M, Lanchbury, J S, Kaye, S B, Gourley, C, Bowtell, D D L, Kohn, E C, Scott, C L, Matulonis, U A, Panzarella, T, Karakasis, K, Burnier, J V, Gilks, B, O'connor, M J, Robertson, J D, Ledermann, J, Barrett, J C, Ho, T W & Oza, A M 2017, ' Long-term responders on olaparib maintenance in high-grade serous ovarian cancer: Clinical and molecular characterization ', Clinical Cancer Research, vol. 23, no. 15, pp. clincanres.2615.2016 . https://doi.org/10.1158/1078-0432.CCR-16-2615Test
مصطلحات موضوعية: Adult, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, endocrine system diseases, DNA repair, medicine.medical_treatment, Antineoplastic Agents, Poly(ADP-ribose) Polymerase Inhibitors, Bioinformatics, Placebo, Disease-Free Survival, Piperazines, law.invention, Olaparib, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Randomized controlled trial, Maintenance therapy, law, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Aged, BRCA2 Protein, Ovarian Neoplasms, Chemotherapy, BRCA1 Protein, business.industry, Cancer, Middle Aged, medicine.disease, Clinical trial, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, Mutation, Phthalazines, Female, Neoplasm Grading, Neoplasm Recurrence, Local, Tumor Suppressor Protein p53, business
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18ebb617095ff01ea1c8bb88afab437dTest
https://doi.org/10.1158/1078-0432.ccr-16-2615Test -
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المؤلفون: Antonis Kattamis, Maria Domenica Cappellini, Martin H. Steinberg, Franco Locatelli, Josu de la Fuente, Sandeep Soni, Damiano Rondelli, Suzan Imren, Sujit Sheth, Tony W. Ho, Stephan A. Grupp, Yimeng Lu, Michael J. Weinstein, Donna A. Wall, Markus Y. Mapara, John K. Wu, Yael Bobruff, Haydar Frangoul, Rupert Handgretinger, Selim Corbacioglu, Sarah D. Mulcahey, J Lekstrom-Himes, Mariane de Montalembert, Niraj Shanbhag, C. Fernández
المصدر: Blood. 136:3-4
مصطلحات موضوعية: business.industry, Thalassemia, education, Immunology, Cell, CD34, Cell Biology, Hematology, medicine.disease, Biochemistry, Haematopoiesis, medicine.anatomical_structure, Medicine, Climb, CRISPR, In patient, Progenitor cell, business, health care economics and organizations
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::51825e58e3d346f75b0a6ca5dd93bca1Test
https://doi.org/10.1182/blood-2020-139575Test -
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المؤلفون: Dana Adriana Botesteanu, Elizabeth D. Thompson, Maria I. Harrell, Tony W. Ho, Cody J. Peer, Aleksandra Ogurtsova, Haiying Xu, Janis M. Taube, Ashley Cimino-Mathews, Jung-Min Lee, Christina M. Annunziata, Alexandra Zimmer, Elizabeth M. Swisher, Stanley Lipkowitz, William D. Figg, Jeffers Nguyen, Liang Cao, Nicole D. Houston, Elise C. Kohn
المصدر: Journal of Clinical Oncology. 35:2193-2202
مصطلحات موضوعية: Adult, 0301 basic medicine, Cancer Research, medicine.medical_specialty, Durvalumab, Combination therapy, Genital Neoplasms, Female, Poly(ADP-ribose) Polymerase Inhibitors, Pharmacology, Gastroenterology, B7-H1 Antigen, Piperazines, Olaparib, Cediranib, 03 medical and health sciences, chemistry.chemical_compound, Lymphocytes, Tumor-Infiltrating, 0302 clinical medicine, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Adverse effect, Protein Kinase Inhibitors, Aged, Vascular Endothelial Growth Factor Receptor-1, Dose-Response Relationship, Drug, business.industry, Area under the curve, Antibodies, Monoclonal, ORIGINAL REPORTS, Middle Aged, Dose–response relationship, 030104 developmental biology, Oncology, chemistry, 030220 oncology & carcinogenesis, Toxicity, Quinazolines, Phthalazines, Female, business, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e881cebef7d9615b87f95069c85fdf6Test
https://doi.org/10.1200/jco.2016.72.1340Test -
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المؤلفون: Jane Robertson, Anitra Fielding, Zhongwu Lai, Mark J. O'Connor, Kirsten Timms, Tony W. Ho, Jonathan A. Ledermann, Maria Orr, Stuart Spencer, J. Carl Barrett, Helen Jones, Darren Hodgson, Chris Womack, Jerry S. Lanchbury, Alexander Gutin, Lynda Grinsted, Brian Dougherty, Charlie Gourley, Blake Gilks
المصدر: Hodgson, D R, Dougherty, B A, Lai, Z, Fielding, A, Grinsted, L, Spencer, S, O’connor, M J, Ho, T W, Robertson, J D, Lanchbury, J S, Timms, K M, Gutin, A, Orr, M, Jones, H, Gilks, B, Womack, C, Gourley, C, Ledermann, J & Barrett, J C 2018, ' Candidate biomarkers of PARP inhibitor sensitivity in ovarian cancer beyond the BRCA genes ', British Journal of Cancer . https://doi.org/10.1038/s41416-018-0274-8Test
British Journal of Cancerمصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, DNA repair, Population, Poly(ADP-ribose) Polymerase Inhibitors, medicine.disease_cause, Article, Olaparib, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Double-Blind Method, Internal medicine, medicine, Biomarkers, Tumor, Humans, education, BRCA2 Protein, Ovarian Neoplasms, education.field_of_study, Mutation, business.industry, BRCA1 Protein, Methylation, medicine.disease, Clinical trial, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, PARP inhibitor, Female, business, Ovarian cancer
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b0161853805f94870acd38f5d6cbae5Test
https://www.pure.ed.ac.uk/ws/files/76353096/2018_Oct_CG_Candidate_biomarkers_of_PARP_inhibitor_sensitivity_in_ovarian_cancer_beyond_the_BRCA_genes.pdfTest