المؤلفون: Hartz, Richard A., Ahuja, Vijay T., Luo, Guanglin, Chen, Ling, Sivaprakasam, Prasanna, Xiao, Hong, Krause, Carol M., Clarke, Wendy J., Xu, Songmei, Tokarski, John S., Kish, Kevin, Lewis, Hal, Szapiel, Nicolas, Ravirala, Ramu, Mutalik, Sayali, Nakmode, Deepa, Shah, Devang, Burton, Catherine R., Macor, John E., Dubowchik, Gene M.

المصدر: Journal of Medicinal Chemistry ; volume 66, issue 11, page 7534-7552 ; ISSN 0022-2623 1520-4804

مصطلحات موضوعية: Drug Discovery, Molecular Medicine

الإتاحة: https://doi.org/10.1021/acs.jmedchem.3c00364Test

المؤلفون: Locke, Gregory A., Muckelbauer, Jodi, Tokarski, John S., Barbieri, Christopher M., Belić, Stefan, Falk, Bradley, Tredup, Jeffrey, Wang, Ying-Kai

المصدر: Methods in Enzymology ; Pseudokinases ; page 685-727 ; ISSN 0076-6879 ; ISBN 9780323915410

الإتاحة: https://doi.org/10.1016/bs.mie.2022.03.051Test
https://api.elsevier.com/content/article/PII:S0076687922001422?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0076687922001422?httpAccept=text/plainTest

المؤلفون: Khojasteh, S Cyrus, Argikar, Upendra A, Driscoll, James P, Heck, Carley JS, King, Lloyd, Jackson, Klarissa D, Jian, Wenying, Kalgutkar, Amit S, Miller, Grover P, Kramlinger, Valerie, Rietjens, Ivonne MCM, Teitelbaum, Aaron M, Wang, Kai, Wei, Cong, Johnson, Benjamin M, Shu, Yue-Zhong, Zhuo, Xiaoliang, Meanwell, Nicholas A, Cerny, Matthew A, Obach, R Scott, Sharma, Raman, Spracklin, Douglas K, Walker, Gregory S, Goracci, Laura, Desantis, Jenny, Valeri, Aurora, Castellani, Beatrice, Eleuteri, Michela, Cruciani, Gabriele, Lall, Manjinder S, Bassyouni, Asser, Bradow, James, Brown, Maria, Bundesmann, Mark, Chen, Jinshan, Ciszewski, Gregory, Hagen, Anne E, Hyek, Dennis, Jenkinson, Stephen, Liu, Bo, Pan, Senliang, Reilly, Usa, Sach, Neal, Smaltz, Daniel J, Starr, Jeremy, Wagenaar, Melissa, de Bruyn Kops, Christina, Sicho, Martin, Mazzolari, Angelica, Kirchmair, Johannes, Korprasertthaworn, Porntipa, Chau, Nuy, Nair, Pramod C, Rowland, Andrew, Miners, John O, Wrobleski, Stephen T, Moslin, Ryan, Lin, Shuqun, Zhang, Yanlei, Spergel, Steven, Kempson, James, Tokarski, John S, Strnad, Joann, Zupa-Fernandez, Adriana, Cheng, Lihong, Shuster, David, Gillooly, Kathleen, Yang, Xiaoxia, Heimrich, Elizabeth, McIntyre, Kim W, Chaudhry, Charu, Khan, Javed, Ruzanov, Max, Tredup, Jeffrey, Mulligan, Dawn, Xie, Dianlin, Sun, Huadong, Huang, Christine, D'Arienzo, Celia, Aranibar, Nelly, Chiney, Manoj, Chimalakonda, Anjaneya, Pitts, William J, Lombardo, Louis, Carter, Percy H, Burke, James R, Weinstein, David S, Li, Jing, Liu, Ju, Enders, Jennifer, Arciprete, Michael, Tran, Chris, Aluri, Krishna, Guan, Li-Hua, O'Shea, Jonathan, Bisbe, Anna, Charisse, Klaus, Zlatev, Ivan, Najarian, Diana, Xu, Yuanxin, Kim, Jaeah, El Zahar, Noha M, Bartlett, Michael G, Katyayan, Kishore, Yi, Ping, Monk, Scott, Cassidy, Kenneth, Takahashi, Ryan H, Grandner, Jessica M, Bobba, Sudheer, Liu, Yanzhou, Beroza, Paul, Zhang, Donglu, Ma, Shuguang, Post, Noah, Yu, Rosie, Greenlee, Sarah, Gaus, Hans, Hurh, Eunju, Matson, John, Wang, Yanfeng, Tajima, Yuya, Toyoda, Takeshi, Hirayama, Yuichiro, Matsushita, Kohei, Yamada, Takanori, Ogawa, Kumiko, Watanabe, Kenji, Takamura-Enya, Takeji, Totsuka, Yukari, Wakabayashi, Keiji, Miyoshi, Noriyuki, Zhang, Jiayin, Chan, Chi-Kong, Ham, Yat-Hing, Chan, Wan, Schleiff, Mary Alexandra, Flynn, Noah R, Payakachat, Sasin, Schleiff, Benjamin Mark, Pinson, Anna O, Province, Dennis W, Swamidass, S Joshua, Boysen, Gunnar, Nardone-White, Dasean T, Bissada, Jennifer E, Abouda, Arsany A, Zhang, Zhuming, Connolly, Peter J, Lim, Heng Keang, Pande, Vineet, Meerpoel, Lieven, Teleha, Christopher, Branch, Jonathan R, Ondrus, Janine, Hickson, Ian, Bush, Tammy, Luistro, Leopoldo, Packman, Kathryn, Bischoff, James R, Ibrahim, Salam, Parrett, Christopher, Chong, Yolanda, Gottardis, Marco M, Bignan, Gilles, Mulder, Teresa, Bobba, Sudder, Johnson, Kevin M, Wang, Wei, Zhang, Chenghong, Cai, Jingwei, Choo, Edna F, Crawford, James J, Landry, Matthew L, Chen, Huifen, Kenny, Jane R, Lee, Wendy, Young, Wendy B, Geib, Timon, Thulasingam, Madhuranayaki, Haeggstrom, Jesper Z, Sleno, Lekha, Monroe, James J, Tanis, Keith Q, Podtelezhnikov, Alexei A, Nguyen, Truyen, Machotka, Sam V, Lynch, Donna, Evers, Raymond, Palamanda, Jairam, Miller, Randy R, Pippert, Todd, Cabalu, Tamara D, Johnson, Timothy E, Aslamkhan, Amy G, Kang, Wen, Tamburino, Alex M, Mitra, Kaushik, Agrawal, Nancy GB, Sistare, Frank D

المصدر: Drug Metabolism Reviews 53 (2021) 3
Drug Metabolism Reviews, 53(3), 384-433

مصطلحات موضوعية: METABOLISM, Toxicology, 030226 pharmacology & pharmacy, 03 medical and health sciences, nonp450 enzymes, 0302 clinical medicine, p450 enzymes, Biotransformation, INTRINSIC CLEARANCE, Political science, MASS-BALANCE, Humans, Pharmacology (medical), Pharmacology & Pharmacy, P450 Enzymes, General Pharmacology, Toxicology and Pharmaceutics, ANTISENSE OLIGONUCLEOTIDE, Toxicologie, VLAG, ARISTOLOCHIC ACID, Drug metabolism, Science & Technology, WIMEK, bioactivation, IDENTIFICATION, Year in review, IN-VITRO, NONHEPATOTOXIC DRUGS, Drug metabolizing enzymes, Drug development, 030220 oncology & carcinogenesis, COVALENT BINDING DATA, Engineering ethics, biotransformation, LIVER-MICROSOMES, Life Sciences & Biomedicine

وصف الملف: application/pdf; Print-Electronic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a22a3073b1b8be7c5621703d8a65f67Test
https://doi.org/10.1080/03602532.2021.1916028Test

المؤلفون: Stephen T. Wrobleski, Hart Amy C, Moslin Ryan M, Robert M. Borzilleri, Tokarski John S

المصدر: Burger's Medicinal Chemistry and Drug Discovery. :1-86

مصطلحات موضوعية: business.industry, Immunology, Medicine, JAK Family, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::346314e8fd3ddb9cb747245e50d6ae4fTest
https://doi.org/10.1002/0471266949.bmc279Test

المؤلفون: Hynes, John, Dyckman, Alaric J., Lin, Shuqun, Wrobleski, Stephen T., Wu, Hong, Gillooly, Kathleen M., Kanner, Steven B., Lonial, Herinder, Loo, Derek, McIntyre, Kim W., Pitt, Sidney, Shen, Ding Ren, Shuster, David J., Yang, Xiaoxia, Zhang, Rosemary F., Behnia, Kamelia, Zhang, Hongjian, Marathe, Punit H., Doweyko, Arthur M., Tokarski, John S., Sack, John S., Pokross, Matthew E., Kiefer, Susan E., Newitt, John A., Barrish, Joel C., Dodd, John H., Schieven, Gary L., Leftheris, Katerina

المصدر: Journal of medicinal chemistry (N-cyclopentyl-4-(2-methyl-5-(methoxycarbamoyl)phenylamino)-5-methylpyrrol o(2,1-f)(1,2,4)triazine-6-carboxamide) (N-ethyl-4-(2-methyl-5-(methoxycarbamoyl)phenylamino)-5-methylpyrrolo(2,1- f)(1,2,4)triazine-6-carboxamide) ; 51 ; 1 ; 4-16

مصطلحات موضوعية: Life Sciences, Medicine and Health Sciences

العلاقة: Link to Article in PubMed; http://dx.doi.org/10.1021/jm7009414Test; J Med Chem. 2008 Jan 10;51(1):4-16. Epub 2007 Dec 12. Link to article on publisher's site; 0022-2623 (Print); http://hdl.handle.net/20.500.14038/32868Test; https://escholarship.umassmed.edu/gsbs_sp/1421Test; 727711; gsbs_sp/1421

الإتاحة: https://doi.org/10.1021/jm7009414Test
https://doi.org/20.500.14038/32868Test
https://hdl.handle.net/20.500.14038/32868Test
https://escholarship.umassmed.edu/gsbs_sp/1421Test

المؤلفون: Hill, Matthew D., Fang, Haiquan, Norris, Derek, Delucca, George V., Huang, Hong, DeBenedetto, Mikkel, Quesnelle, Claude, Schmitz, William D., Tokarski, John S., Sheriff, Steven, Yan, Chunhong, Fanslau, Caroline, Haarhoff, Zuzana, Huang, Christine, Kramer, Melissa, Madari, Shilpa, Menard, Krista, Monereau, Laura, Morrison, John, Raghavan, Nirmala, Shields, Eric E., Simmermacher-Mayer, Jean, Sinz, Michael, Tye, Ching Kim, Westhouse, Richard, Xie, Chunshan, Zhang, Haiying, Zhang, Lisa, Zvyaga, Tatyana, Lee, Francis, Gavai, Ashvinikumar V., Degnan, Andrew P.

المصدر: ACS Medicinal Chemistry Letters ; volume 13, issue 7, page 1165-1171 ; ISSN 1948-5875 1948-5875

مصطلحات موضوعية: Organic Chemistry, Drug Discovery, Biochemistry

الإتاحة: https://doi.org/10.1021/acsmedchemlett.2c00219Test

المؤلفون: Tokarski, John S., Zupa-Fernandez, Adriana, Tredup, Jeffrey A., Pike, Kristen, Chang, ChiehYing, Xie, Dianlin, Cheng, Lihong, Pedicord, Donna, Muckelbauer, Jodi, Johnson, Stephen R., Wu, Sophie, Edavettal, Suzanne C., Hong, Yang, Witmer, Mark R., Elkin, Lisa L., Blat, Yuval, Pitts, William J., Weinstein, David S., Burke, James R.

المصدر: Journal of Biological Chemistry ; volume 290, issue 17, page 11061-11074 ; ISSN 0021-9258

مصطلحات موضوعية: Cell Biology, Molecular Biology, Biochemistry

الإتاحة: https://doi.org/10.1074/jbc.m114.619502Test
https://api.elsevier.com/content/article/PII:S0021925820426328?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0021925820426328?httpAccept=text/plainTest

المؤلفون: Chaudhry, Charu, Tebben, Andrew, Tokarski, John S., Borzilleri, Robert, Pitts, William J., Lippy, Jonathan, Zhang, Litao

المصدر: Drug Discovery Today ; volume 26, issue 5, page 1115-1125 ; ISSN 1359-6446

مصطلحات موضوعية: Drug Discovery, Pharmacology

الإتاحة: https://doi.org/10.1016/j.drudis.2021.01.018Test
https://api.elsevier.com/content/article/PII:S1359644621000489?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S1359644621000489?httpAccept=text/plainTest

المؤلفون: Gavai, Ashvinikumar V., Norris, Derek, Delucca, George, Tortolani, David, Tokarski, John S., Dodd, Dharmpal, O’Malley, Daniel, Zhao, Yufen, Quesnelle, Claude, Gill, Patrice, Vaccaro, Wayne, Huynh, Tram, Ahuja, Vijay, Han, Wen-Ching, Mussari, Christopher, Harikrishnan, Lalgudi, Kamau, Muthoni, Poss, Michael, Sheriff, Steven, Yan, Chunhong, Marsilio, Frank, Menard, Krista, Wen, Mei-Li, Rampulla, Richard, Wu, Dauh-Rurng, Li, Jianqing, Zhang, Huiping, Li, Peng, Sun, Dawn, Yip, Henry, Traeger, Sarah C., Zhang, Yingru, Mathur, Arvind, Zhang, Haiying, Huang, Christine, Yang, Zheng, Ranasinghe, Asoka, Everlof, Gerry, Raghavan, Nirmala, Tye, Ching Kim, Wee, Susan, Hunt, John T., Vite, Gregory, Westhouse, Richard, Lee, Francis Y.

المساهمون: Office of Science

المصدر: Journal of Medicinal Chemistry ; volume 64, issue 19, page 14247-14265 ; ISSN 0022-2623 1520-4804

الإتاحة: https://doi.org/10.1021/acs.jmedchem.1c00625Test